Proxel GXL Antimicrobial: Arch® Biocides

PROXEL™ GXL Antimicrobial TECHNICAL
INFORMATION BULLETIN
Table 1: Minimum Inhibitory Concentrations (MIC)

O Micro-organism PROXEL GXL (ppm)
Bacteria
Bacillus subtilis 40
Burkholderia cepacia 80
NH Enterobacter cloacae 80
Escherichia coli 40
S Proteus vulgaris 125
Pseudomonas aeruginosa 250
Pseudomonas putida 250
PROXEL GXL is a broad spectrum biocide for the Staphylococcus aureus 40
preservation of industrial water-based products against Streptococcus faecalis 40
spoilage from bacteria, yeasts and fungi. Streptococcus lactis 15
PROXEL GXL is a 20% aqueous dipropylene glycol Fungi

solution of 1,2-benzisothiazolin-3-one. Alternaria alternata 700
Aspergillus niger 350
Applications Aureobasidium pullulans 350
PROXEL GXL is effective in a wide range of industrial Chaetomium globosum 400
aqueous-based products. Application areas include: Cladosporium cladosporoides 400
• Synthetic polymer emulsions Penicillium notatum 125
• Emulsion paints
• Water-based adhesives Yeasts
• Household products Candida albicans 200
• Printing inks Rhodotorula rubra 400
• Paper coating compositions Saccharomyces cerevisiae (turbidans) 250
• Metal working fluids
• Agricultural pesticide dispersions
• Aqueous mineral and pigment slurries
• Tape joint compounds
• Leather processing solutions
Antimicrobial Properties
The levels of PROXEL GXL needed to prevent the growth
of problem micro-organisms are listed in Table 1.
MICs do not represent effective use levels but do indicate

the broad spectrum of activity of PROXEL GXL.
PROXEL GXL has a non-specific mode of action which

means that bacterial resistance is very unlikely to occur.
Detailed information on the mode of action of PROXEL
GXL is available on request.
(continued on next page)
Arch® Biocides
Table 2: Typical Physical Properties Amount to Use

Composition A solution of 1,2-benzisothiazolin- PROXEL GXL should be added to the system as early in
3-one in dipropylene glycol and the process as possible. The concentration of PROXEL
water. GXL required to adequately preserve your product depends
on several factors. These include the susceptibility of the
Active agent 20% w/w system to microbiological degradation, the extent to which
micro-organisms can gain access, the species involved,
Physical form Yellow-light brown solution pH, temperature, and length of time for which protection
is required.
Viscosity at 10/25°C 2000/400 mPa s (Newtonian)
A range of concentrations and applications is recommended
pH at 25°C 13.5 in Table 3; however, it is recommended that a testing
programme be undertaken to determine the most cost-
Boiling point 100°C effective dose for your application.
Storage stability Stable under normal conditions of Testing should take into account chemical
storage down to -10°C. If frozen, compatibility/stability, plant hygiene conditions,
allow to thaw and stir well before susceptibility of the product to contamination, and the
use. Active agent is heat-stable and typical organisms involved.
non-volatile.
Technical Service
Flash point Boils without flashing All of these tests can be provided by Arch Biocides’
technical laboratories as part of our customer support
Density at 25°C 1.14 programme. Please contact your nearest technical
department to take advantage of these customised services.
Compatibility Compatible and effective over pH
range 4-12. Stable in the presence
of amines. Incompatible with some
oxidising and reducing agents
e.g. persalts, sulphites.
Arch® Biocides
Table 3: Applications Risk Assessment and Management

Product % PROXEL GXL (w/w) Highly qualified Arch Safety, Health and Environment
(SHE) professionals are available to help define and
Synthetic polymer emulsions: 0.05-0.15 manage any potential risks to human health or to the
environment when using PROXEL preservative products.
Emulsion paints: 0.05-0.15 In addition, Arch Biocides is committed to understanding
the suitability of PROXEL GXL for specific applications.
Water-based adhesives: 0.05-0.25 Please contact your local Arch sales office should you have
questions in this area.
Household products: 0.05-0.15
Including Health and Safety
Laundry detergents, Fabric softeners, Arch Biocides maintains Material Safety Data Sheets on all
Dish-washing liquids, Floor and wall of its products. These are regularly updated to incorporate
cleaning solutions, Surface cleaning new data under our continuous programme to improve our
products, Window cleaners, health and safety advice needed to protect your employees
Floor polishes and waxes, Shoe polishes and customers.
Tape joint compounds: 0.05-0.25 The PROXEL GXL Material Safety Data Sheet is provided
with every sample and product shipment and is also
Printing inks: 0.05-0.15 supplied upon request. It should be read and understood by
all supervisory personnel and employees before using this
Paper coating compositions: 0.05-0.15 product. If there is any doubt please contact your local
Arch sales office for advice.
Metal working fluids: 0.05-0.18
Total Quality
Agricultural pesticide products: 0.05-0.25 Arch Biocides has ISO 9002 registration at its Business
Centre and manufacturing sites.
Aqueous mineral and pigment slurries: 0.05-0.15
Leather processing solutions: 0.05-0.25

For the short term preservation of
freshly flayed skins & hides during
processing.
Arch® Biocides
Regulatory Information
PROXEL GXL has many worldwide regulatory approvals.
For example, it is cleared by the German BgVV and US
EPA registration.
Since approvals are regularly being gained, we are

constantly updating our records. A full, up to date list is
available on request.
The components of PROXEL GXL are listed on the

following inventories:
EINECS (Europe)
TSCA (USA)
ACOIN/AICS (Australia)
MITI (Japan)
DSL (Canada)
Korean inventory
Philippine inventory
Enquiries for further information and samples should be

addressed to your local sales office: Use biocides safely. Always read the label and product
information before use.
Some Arch Chemicals, Inc. biocides may not be registered

for certain uses in your country.
Arch® Biocides is a business unit of Arch Chemicals Inc.
Any data relating to test organisms included in this

publication relates to standard laboratory test species and is
provided for information only. No claim of controlling
organisms in public health applications is made by the
inclusion of such data nor should it be implied.
No statement herein is intended as a representation or

warranty regarding PROXEL or any other product of Arch
Chemicals, Inc.
PROXEL is a trademark, the property of Arch UK Biocides Ltd., a subsidiary of Arch Chemicals, Inc.
SAFE HANDLING INFORMATION

Refer to the Material Safety Data Sheet (MSDS) available from Arch Chemicals, Inc. for information on the safe use, handling and
disposal of this product.
Arch® Biocides
Phone: (800) 523-7391 FAX: (866) 705-0465
1955 Lake Park Drive, Suite 100, Smyrna, GA 30080 ©2007 Arch Chemicals, Inc.
www.archbiocides.com 2-00170-R3

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PROXEL™ GXL Antimicrobial TECHNICAL

Table 1: Minimum Inhibitory Concentrations (MIC)

PROXEL GXL is a 20% aqueous dipropylene glycol Fungi

MICs do not represent effective use levels but do indicate

PROXEL GXL has a non-specific mode of action which

(continued on next page)

Table 2: Typical Physical Properties Amount to Use

(continued on next page)

Table 3: Applications Risk Assessment and Management

Leather processing solutions: 0.05-0.25

(continued on next page)

Since approvals are regularly being gained, we are

The components of PROXEL GXL are listed on the

Enquiries for further information and samples should be

Some Arch Chemicals, Inc. biocides may not be registered

Arch® Biocides is a business unit of Arch Chemicals Inc.

Any data relating to test organisms included in this

No statement herein is intended as a representation or

SAFE HANDLING INFORMATION

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