1

RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES,

KARNATAKA, BANGALORE.

COMPLETED PROFORMA FOR REGISTRATION OF SUBJECT FOR DISSERTATION

“A COMPARATIVE STUDY OF BHRINGARAJADYA TAILA NASYA AND

KUMARIKA VARTI ANJANA IN TIMIRA W.S.R TO IMMATURE
CATARACT”

BY

RENU V.T
PG SCHOLAR
DEPT., OF PG STUDIES IN SHALAKYATANTRA
SKAMCH & RC, VIJAYANAGAR, BANGALORE – 560 104

GUIDE
DR. HAMSAVENI V. MS (AYU)
READER
DEPT., OF PG STUDIES IN SHALAKYATANTRA
SKAMCH & RC, VIJAYANAGAR, BANGALORE – 560 104

CO-GUIDE
DR. MAMATHA K.V. MS (AYU)
READER
DEPT., OF P G STUDIES IN SHALAKYATANTRA
SKAMCH & RC, VIJAYANAGAR, BANGALORE – 560 104

2012 - 2013

SRI KALABYRAVESHWARASWAMY AYURVEDIC MEDICAL COLLEGE, HOSPITAL &

RESEARCH CENTRE, VIJAYANAGAR, BANGALORE – 560 104
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From,
RENU V.T
PG SCHOLAR
DEPT., OF P G STUDIES IN SHALAKYATANTRA,
SKAMCH & RC,
VIJAYANAGAR, BANGALORE – 560 104

To,
THE REGISTRAR,
RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES,
KARNATAKA, BANGALORE.

Through,
THE PRINCIPAL,
DEAN OF PG STUDIES AND HOD OF PG STUDIES IN SHALAKYATANTRA
SKAMCH & RC,
VIJAYANAGAR, BANGALORE – 560 104

Respected Sir,

Subject: Submission of completed proforma for registration of the subject for dissertation

I request you to kindly register the below mentioned subject against my name for the submission of
dissertation to Rajiv Gandhi University of Health Sciences, Bangalore for the partial fulfilment of MS(Ayu) in
Shalakyatantra.

TITLE OF THE DISSERTATION

“A COMPARATIVE STUDY OF BHRINGARAJADYA TAILA NASYA AND

KUMARIKA VARTI ANJANA IN TIMIRA W.S.R TO IMMATURE CATARACT”

Herewith I am enclosing the completed proforma for registration of subject for dissertation.
Thanking You,

Yours faithfully,
Date:
Place: Bangalore (RENU V.T)
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RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES,

KARNATAKA, BANGALORE.

ANNEXURE – II

PROFORMA FOR REGISTRATION OF SUBJECTS FOR DISSERTATION

1) NAME OF THE CANDIDATE RENU V.T
AND ADDRESS PG SCHOLAR
DEPT., OF P G STUDIES
IN SHALAKYATANTRA
SKAMCH & RC,
#10, PIPELINE ROAD, R.P.C. LAYOUT,
VIJAYANAGAR, BANGALORE – 560 104

2) PERMANENT ADDRESS D/O V.T. JAYAPRAKASH

THOTTATHIL HOUSE
PO AYILAKKAD, VIA.EDAPPAL
DIST. MALAPPURAM,
KERALA – 679 576

3) NAME OF THE INSTITUTION SRI KALABYRAVESHWARASWAMY

AYURVEDIC MEDICAL COLLEGE, HOSPITAL &
RESEARCH CENTRE,
#10, PIPELINE ROAD, R.P.C. LAYOUT,
VIJAYANAGAR, BANGALORE – 560 104

4) COURSE OF STUDY AND MS (AYU) IN SHALAKYATANTRA

SUBJECT

5) DATE OF ADMISSION 28th OCTOBER 2012

TO COURSE

TITLE OF THE TOPIC

“A COMPARATIVE STUDY OF BHRINGARAJADYA TAILA NASYA AND
KUMARIKA VARTI ANJANA IN TIMIRA W.S.R TO IMMATURE CATARACT”
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6) BRIEF RESUME OF THE INTENDED WORK

6.1) Need for the Study:

Any opacity in the lens or its capsule, whether developmental or acquired is called as Cataract. 1 Age
related cataracts are responsible for 51% of world blindness, about 21million people 2 and the condition is almost
universal in varying degree in persons over 40 years of age. It occurs equally in men and women.

Ayurveda has explained Timira roga under drishtirogas.3 Clinical features of dwitheeya patalagatha timira
such as vihwala drushti, dooram sukshmam cha na eekshathe etc. can be correlated to that of immature cataract.

In conventional system of medicine, the only definite management is lens extraction once it reaches matured
stage or complete opacification. Over 90% cataract surgeries are successful 4 but complications though rare are
more serious which includes sensitivity to anaesthesia, uveitis, retinal detachment, subluxation of lens etc.5

The study of immature cataract bears importance because it can be reversible in the stage of lamellar
separation and prophylactic measures in the other stages of immature cataract can delay and prevent leading to
complete opacification.6 Medicines and procedures administered should be cost effective and easily applicable,
without any adverse reactions. Nasya7 and Anjana karma8 are described among the procedures mentioned in
Timira roga. Hence the present study is being taken up to evaluate the efficacy of Bhringarajadya taila Nasya 9
and Kumarika varti Anjana10 which can effectively arrest the progression of lens opacity, as per Ayurvedic texts.

6.2) Review of literature:


Dristigata rogas are explained depending upon the vitiation of doshas in various patalas. According to
Sushruta, vitiation of doshas in prathama, dwitheeya and tritheeya patalas is described as Timira 11; where
as Vagbhata mentions that Timira is occurring in prathama and dwitheeya patalas.12

Description of lakshanas of timira explained in Susruta samhitha13 and Ashtanga hridaya.14
 Description of chikitsa of timira explained in Susruta samhitha15 and Ashtanga hridaya.16


Description of drugs used and method of preparation of Bhringarajadya taila explained in Vangasena.

Description of drugs used and method of preparation of Kumarika varti explained in Chakradatta.

Detailed description of clinical features of cataract and immature cataract explained in allied science.

Previous work done

 Prasad Rao – Management of Timira with Anutaila nasya; Dr BKRR Govt. Ayurveda college,
Andhrapradesh University, Vijayawada; 1991.
 Janardan Rao – Management of Timira with Nasya, with or without Saptamrutha Lauha;
Dr BKRR Govt. Ayurveda college, Andhrapradesh University, Vijayawada; 1994.
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 Gupta A M – Role of Swarnagyrikanjana in Timira w.s.r. to Immature Cataract; IPGTRA, Gujarat

Ayurveda University, Jamnagar; 1997.
 Manjusha R – Role of Manahshiladi Anjana and Jeevantyadi Ghrita on Linganasha (Cataract); IPGTRA,
Gujarat Ayurveda University, Jamnagar; 2004.
 Sandya Ganesh K – Role of Lekhana Putapaka and Lekhananjana in the Management of Kaphajakacha,
A Comparative Clinical Study, GAMC Bangalore, Rajiv Gandhi University of Health Sciences; 2004.
 Chaithanya M – A Clinical Study of Kusumika Varthi Anjana and Eye Exercises in the Management of
Prathama Patalagatha Timira w.s.r. to Simple myopia; SDM College of Ayurveda and Hospital, Hassan,
Rajiv Gandhi University of Health Sciences; 2007.
 Divya Stuvert – Role of Abhijith taila nasya in the management of Prathama patalagatha timira w.s.r. to
Simple myopia; SDM College of Ayurveda and Hospital, Hassan, Rajiv Gandhi University of Health
Sciences; 2008.

6.3) Objectives of the Study

 To evaluate the efficacy of Bhringarajadya taila Nasya in the management of Timira.
 To evaluate the efficacy of Kumarika varti Anjana in the management of Timira.
 To compare the efficacy of Bhringarajadya taila Nasya and Kumarika Varti Anjana in Timira.

7) MATERIALS AND METHODS:

7.1) Source of data
The patients with clinical features of Timira will be selected from OPD and IPD of Shalakya Tantra
Department of Sri Kalabyraveshwara Swamy Ayurvedic Medical College, Hospital and Research Centre,
Bangalore.

7.2) Method of collection of data

 It is a comparative clinical study, where in 40 patients of either sex, diagnosed as Timira, will be
randomly assigned into 2groups, each comprising of 20 patients.
 A case proforma will be specially designed with all points of history-taking, physical signs and
symptoms.
 The parameters of signs and symptoms will be scored as mentioned in the proforma.
 The data obtained in both groups will be recorded, tabulated and statistically analysed using suitable
statistical methods.
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Diagnostic Criteria
 Patients presenting with clinical features of Timira.
 Diminished Visual acuity up to 6/36
 Immature cataract confirmed by ophthalmoscopy, slit lamp biomicroscopy and presence of iris shadow.
Inclusion Criteria
 Patients with signs and symptoms of Timira.
 Patients fulfilling diagnostic criteria.
 Age above 40 years.
 Disturbance in vision (diplopia, polyopia, halos)

Exclusion Criteria
 Post surgical Cataract.
 Mature Cataract
 Sluggish pupil reaction
 Complicated Cataract ie.cataract secondary to other ocular diseases like Glaucoma,
Optic atrophy, Macular degeneration, Posterior segment disorders.
 Nasya anarhas
 Anjana anarhas

Study design
 This is a comparative clinical study with pre test and post test design will be conducted on 40patients
with signs and symptoms of Timira or Immature cataract.

Intervention
40 patients of Timira will be selected randomly and divided into 2 groups, Group-A and Group-B.
Group Chikitsa Vidhi Avadhi
A Nasya with Sthanika 3 Sittings of 7days Nasya karma
Bhringarajadya taila abhyanga and with an interval of 9days- total
Bashpa sweda 48days
followed by
Nasya- Once
daily in the
morning, 8drops
in each nostril.
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B Anjana with Once daily in 48 consecutive days.

Kumarika varti the morning

Duration
Total duration of treatment shall be 48days in each group.

Assessment Criteria:
Assesment of the clinical study will be done on subjective and objective parameters based on the proforma.

7.3) Does this study require any investigations or interventions to be conducted on the
patients or other humans or animals?
YES

Investigation
 Blood for RBS.

7.4) Has ethical clearance been obtained from your institution in case of 7.3?
YES

8) List of References:
1) Stephen J H Miller, Parsons’ diseases of the eye, Churchill Livingstone International Student Editions,
18thEdition, 1990, Chapter19, pp - 442, pg - 195.
2) WHO, http://www.who.int/blindness/causes/priority/en/index1.html.
3) Susruta, SusrutaSamhita, Nibandhasamgrahatika of Dalhana and Nyaya Chandrikatika of Gayadasa,
Chowkhamba Krishnadas Academy Varanasi, Edition – 2009, Uthara Sthana, Chapter 7 , Verse-5, pp -
824, pg – 606.
4) College of Medicine at Chicago, (University of Illinois)
http://chicago.medicine.uic.edu/departments___programs/departments/eye.
5) A K Khurana, Comprehensive Ophthalmology, New age international (P) Limited, Publishers, 4 th
Edition-2007, Reprint-2011,chapter-8, pp-605, pg- 197-204.
6) A K Khurana, Comprehensive Ophthalmology, New age international (P) Limited, Publishers, 4 th
Edition-2007, Reprint-2011,chapter-8, pp-605, pg- 176.
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7) Vagbhata, Astangahrdaya, Sarvangasundara of Arunadatta and Ayurvedarasayana of Hemadri,

Chowkhamba Sanskrit Series Office Varanasi, Edition – 2009, Suthra sthana, Chapter 20, Verse- 9,10,
pp -956, pg -289.
8) Susruta, SusrutaSamhita, Nibandhasamgrahatika of Dalhana and Nyaya Chandrikatika of Gayadasa,
Chowkhamba Krishnadas Academy Varanasi, Edition – 2009, Uthara tantra, Chapter 18 , Verse 51-65,
pp - 824, pg -636, 637.
9) Kavivara Shri Shaligramaji Vaishya, Vangasena Hindi Tika sahitha, Khemraj Srikrishnadaass
publication, Edition: 1996, verse-428, pp-1096, pg-790.
10) Chakrapanidatta, Chakradatta, Sanskrit text with English translation, Edited and translated by P V
Sharma, Chaukhamba publishers Varanasi, Edition 2007,Chapter-59, Verse-114, pp-731, pg-497.
11) Susruta, SusrutaSamhita, Nibandhasamgrahatika of Dalhana and Nyaya Chandrikatika of Gayadasa,
Chowkhamba Krishnadas Academy Varanasi, Edition – 2009, Uthara tantra, Chapter 7 , Verse-6-14, pp -
824, pg – 606.
12) Vagbhata, Astangahrdaya, Sarvangasundara of Arunadatta and Ayurvedarasayana of Hemadri,
Chowkhamba Sanskrit Series Office Varanasi, Edition – 2009, Uthara sthana, Chapter 12, Verse- 1-5, pp
-956, pg- 816,817.
13) Susruta, SusrutaSamhita, Nibandhasamgrahatika of Dalhana and Nyaya Chandrikatika of Gayadasa,
Chowkhamba Krishnadas Academy Varanasi, Edition – 2009, Uthara tantra, Chapter 7 , Verse-6-24, pp -
824, pg – 606.
14) Vagbhata, Astangahrdaya, Sarvangasundara of Arunadatta and Ayurvedarasayana of Hemadri,
Chowkhamba Sanskrit Series Office Varanasi, Edition – 2009, Uthara sthana, Chapter 12, Verse- 1-16,
pp -956, pg- 816,817.
15) Susruta, SusrutaSamhita, Nibandhasamgrahatika of Dalhana and Nyaya Chandrikatika of Gayadasa,
Chowkhamba Krishnadas Academy Varanasi, Edition – 2009, Uthara tantra, Chapter 17 , Verse- 29-43,
pp - 824, pg – 624.
16) Vagbhata, Astangahrdaya, Sarvangasundara of Arunadatta and Ayurvedarasayana of Hemadri,
Chowkhamba Sanskrit Series Office Varanasi, Edition – 2009, Uthara sthana, Chapter13, Verse- 2-80,
pp -956, pg- 818-824.
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9) SIGNATURE OF THE CANDIDATE:

10) REMARKS OF GUIDE:

11) NAME AND DESIGNATION OF (IN BLOCK LETTERS):

11.1) GUIDE DR. HAMSAVENI V. MS (AYU)

READER
DEPT., OF PG STUDIES IN SHALAKYATANTRA
SKAMCH & RC,
VIJAYANAGAR, BANGALORE – 560 104
11.2) SIGNATURE

11.3) CO-GUIDE DR. MAMATHA K.V. MS (AYU)

READER
DEPT., OF PG STUDIES IN SHALAKYATANTRA
SKAMCH & RC,
VIJAYANAGAR, BANGALORE- 560 104

11.4) SIGNATURE

11.5) HEAD OF THE DR. SUJATHAMMA K. MD (AYU)

DEPARTMENT PROFESSOR&HOD
DEPT., OF PG STUDIES INSHALAKYATANTRA
SKAMCH & RC,
VIJAYANAGAR, BANGALORE–560 104

11.6) SIGNATURE

12)

12.1) REMARKS OF THE CHAIRMAN&PRINCIPAL

12.2) SIGNATURE