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Stem Cells Information

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Stem Cells Information

Embryonic Stem cells


Many stem cells are available in embryos. These can grow into any
type of cell found in the body. All tissues and organs could
potentially be grown. Embryos can be produced specifically for
making stem cells and then discarded. This raises ethical issues.
There is no guarantee how successful these therapies will be.
Transplanted tissues and organs may be rejected by the immune
system of patients. It can be difficult to obtain and store a
patient’s embryonic stem cells. Patients could be exploited by
paying for expensive treatments and being given false hope of a
cure as stem cell therapies are only in their developmental stages.
They could be used to replace cells that have been damaged or
destroyed e.g. diabetes and paralysis

Adult Stem Cells


Some stem cells remain in the bodies of adults as adult stem cells.
Their role is to replace body cells that die through injury and
disease. The adult stem cells can only differentiate into cells from
the type of tissue where they are found e.g. blood stem cells make
only blood, and brain stem cells make only brain cell. As the cells are
from the same body they would not reject their own cells. There are
no embryos involved. Adults give permission for their own bone
marrow to be collected. Some human stem cells growing in labs that
researchers have used in experiments to treat serious diseases
contain serious cancer-causing mutations.
Stem Cells Information
Therapeutic Cloning
The process involves the nucleus of a body cell from the patient being
transferred to an egg cell that has had its nucleus removed.  Embryos are
produced specifically making stem cells and then discarded. This raises
ethical issues. There is only a small chance that cells will be rejected by
the patient’s body as the stem cells from the patient are used. Organs
would have an exact match of the patient's DNA.
Therapeutic cloning can help create vital organs. This would be helpful for
people suffering from kidney and other disorders, who are forced to wait
years for a replacement organ. Therapeutic cloning may be helpful for
preventing diseases, research in this area of therapeutic cloning is still
ongoing. The stem cells kept in culture in a lab can show similarities to
cancer cells. The stem cells have undergone about 60 cell divisions and
mutations have been observed. It is also possible for viruses to be
transferred with stem cells, leading to infection.

Extracting eggs from a female is costly and painful for the woman. The
cost of therapeutic cloning is very high.

Umbilical Cord Stem Cells

After a baby is born, stem cells may be collected from blood left in the
umbilical cord. This is a rich source of stem cells that are formed from
the placenta after a child is born and the structure is no longer needed.
These can be frozen and stored for possible use in the future to treat a
medical condition later in that child’s life e.g. a family history of a genetic
disorder. The stem cells are from the same patient so there would be no
rejection. Private cord blood banks let families store the blood for a fee.

There are no ethical issues relating to the use of these stem cells as
embryos aren’t used, but consent from the mother is needed. They could
be used to replace blood cells that have been damaged or destroyed, for
example: blood cell cancer e.g. leukaemia and lymphoma, when blood cells
have been destroyed, e.g during chemotherapy for cancer treatment.

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