Safety Data Sheet

acc. to NOM-018-STPS-2015 and NMX-R-019-SFCI-2011

MALEIC ANHYDRIDE
Version number: GHS 1.0 Date of compilation: 2017-06-05

SECTION 1: Identification
1.1 Product identifier
Identification of the substance MALEIC ANHYDRIDE
CAS number 108-31-6
Synonyms: cis-butenodioic anhydride, Dihydro - 2,5 - dioxofuran, 2,5 - furandiona,
Maleic Acid anhydride, MAA, MALA, Toxílc anhydride, Maleic Abhydride.
1.2 Relevant identified uses of the substance or mixture and uses advised against
Relevant identified uses Industrial use
1.3 Details of the supplier of the safety data sheet
RETER Comercializadora de Productos Petroquímicos S.A. de C.V.
Km. 154 Carr. México - Veracruz
90640 San Cosme Xaloztoc, Tlaxcala
Mexico
 
Telephone: +52 241 413 0000
Website: www.grupoidesa.com
e-mail (competent person) jalvarez@idesa.com.mx (Juan Carlos Alvarez)
1.4 Emergency telephone number
Emergency information service 01-800-00-214-00
Tel. (55) 5559 1588 Cd. de México.
SETIQ

SECTION 2: Hazard(s) identification

2.1 Classification of the substance or mixture
Classification acc. to GHS

Section Hazard class Category Hazard class and Hazard state-

category ment

3.1O acute toxicity (oral) 4 Acute Tox. 4 H302

3.1D acute toxicity (dermal) 5 Acute Tox. 5 H313

3.2 skin corrosion/irritation 1B Skin Corr. 1B H314

3.3 serious eye damage/eye irritation 1 Eye Dam. 1 H318

3.4R respiratory sensitization 1 Resp. Sens. 1 H334

3.4S skin sensitization 1 Skin Sens. 1 H317

3.9 specific target organ toxicity - repeated exposure 1 STOT RE 1 H372

4.1A hazardous to the aquatic environment - acute hazard 3 Aquatic Acute 3 H402

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Version number: GHS 1.0 Date of compilation: 2017-06-05

For full text of abbreviations: see SECTION 16.

The most important adverse physicochemical, human health and environmental effects
Skin corrosion produces an irreversible damage to the skin; namely, visible necrosis through the epidermis and into the dermis.
Delayed or immediate effects can be expected after short or long-term exposure. Spillage and fire water can cause pollution of
watercourses.

2.2 Label elements

Labeling
- Signal word danger
- Pictograms
GHS05, GHS07,
GHS08

- Hazard statements
H302 Harmful if swallowed.
H313 May be harmful in contact with skin.
H314 Causes severe skin burns and eye damage.
H317 May cause an allergic skin reaction.
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H372 Causes damage to organs through prolonged or repeated exposure.
H402 Harmful to aquatic life.

- Precautionary statements
P260 Do not breathe dust/fume/gas/mist/vapors/spray.
P280 Wear protective gloves/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and
easy to do. Continue rinsing.
P342+P311 If experiencing respiratory symptoms: Call a POISON CENTER/doctor.
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/container to industrial combustion plant.

2.3 Other hazards

Results of PBT and vPvB assessment
According to the results of its assessment, this substance is not a PBT or a vPvB.

SECTION 3: Composition/information on ingredients

3.1 Substances
Name of substance MALEIC ANHYDRIDE
Identifiers
CAS No 108-31-6
Molecular formula C4H2O3
Molar mass 98.06 g/mol

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MALEIC ANHYDRIDE
Version number: GHS 1.0 Date of compilation: 2017-06-05

SECTION 4: First-aid measures

4.1 Description of first- aid measures
General notes
Do not leave affected person unattended. Remove victim out of the danger area. Keep affected person warm, still and covered.
Take off immediately all contaminated clothing. In all cases of doubt, or when symptoms persist, seek medical advice. In case
of unconsciousness place person in the recovery position. Never give anything by mouth.
Following inhalation
If breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. In case of respiratory tract ir-
ritation, consult a physician. Provide fresh air.
Following skin contact
Wash with plenty of soap and water.
Following eye contact
Remove contact lenses, if present and easy to do. Continue rinsing. Irrigate copiously with clean, fresh water for at least 10
minutes, holding the eyelids apart.
Following ingestion
Rinse mouth with water (only if the person is conscious). Do NOT induce vomiting.

4.2 Most important symptoms and effects, both acute and delayed
Symptoms and effects are not known to date.

4.3 Indication of any immediate medical attention and special treatment needed
none

SECTION 5: Fire-fighting measures

5.1 Extinguishing media
Suitable extinguishing media
Water, Foam, Alcohol resistant foam, ABC-powder
Unsuitable extinguishing media
Water jet

5.2 Special hazards arising from the substance or mixture

Hazardous combustion products
Nitrogen oxides (NOx), Carbon monoxide (CO), Carbon dioxide (CO2)

5.3 Advice for firefighters

In case of fire and/or explosion do not breathe fumes. Co-ordinate firefighting measures to the fire surroundings. Do not allow
firefighting water to enter drains or water courses. Collect contaminated firefighting water separately. Fight fire with normal pre-
cautions from a reasonable distance.

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SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures
For non-emergency personnel
Remove persons to safety.
For emergency responders
Wear breathing apparatus if exposed to vapors/dust/aerosols/gases.

6.2 Environmental precautions

Keep away from drains, surface and ground water. Retain contaminated washing water and dispose of it.

6.3 Methods and material for containment and cleaning up

Advices on how to contain a spill
Covering of drains, Take up mechanically
Advices on how to clean up a spill
Take up mechanically.
Other information relating to spills and releases
Place in appropriate containers for disposal. Ventilate affected area.

6.4 Reference to other sections

Hazardous combustion products: see section 5. Personal protective equipment: see section 9. Incompatible materials: see sec-
tion 10. Disposal considerations: see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling
Recommendations
- Measures to prevent fire as well as aerosol and dust generation
Use local and general ventilation. Use only in well-ventilated areas. Ground/bond container and receiving equipment.
- Specific notes/details
Dust deposits may accumulate on all deposition surfaces in a technical room. The product in the delivered form is not dust ex-
plosion capable; the enrichment of fine dust however leads to the danger of dust explosion.
Advice on general occupational hygiene
Wash hands after use. Do not eat, drink and smoke in work areas. Remove contaminated clothing and protective equipment be-
fore entering eating areas. Never keep food or drink in the vicinity of chemicals. Never place chemicals in containers that are
normally used for food or drink. Keep away from food, drink and animal feedingstuffs.

7.2 Conditions for safe storage, including any incompatibilities

Managing of associated risks
- Explosive atmospheres
Removal of dust deposits.
- Packaging compatibilities
Only packagings which are approved (e.g. acc. to the Dangerous Goods Regulations) may be used.

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7.3 Specific end use(s)

See section 16 for a general overview.

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Occupational exposure limit values (Workplace Exposure Limits)

Coun Name of agent CAS No Identifi- TWA TWA STEL STEL Source
try er [ppm] [mg/m³] [ppm] [mg/m³]

MX maleic anhydride 108-31-6 VLE 0.01 NOM-010-

STPS
Notation
STEL short-term exposure limit: a limit value above which exposure should not occur and which is related to a 15-minute period unless oth-
erwise specified
TWA time-weighted average (long-term exposure limit): measured or calculated in relation to a reference period of 8 hours time-weighted
average

Human health values

Relevant DNELs and other threshold levels

Endpoint Threshold Protection goal, Used in Exposure time

level route of exposure

DNEL 0.4 mg/m³ human, inhalatory worker (industry) chronic - systemic effects
DNEL 0.8 mg/m³ human, inhalatory worker (industry) acute - systemic effects

DNEL 0.4 mg/m³ human, inhalatory worker (industry) chronic - local effects
DNEL 0.8 mg/m³ human, inhalatory worker (industry) acute - local effects

Environment values

Relevant PNECs and other threshold levels

Endpoint Threshold Organism Environmental compart- Exposure time

level ment

PNEC 0.1 mg/l aquatic organisms freshwater short-term (single instance)

PNEC 0.01 mg/ aquatic organisms marine water short-term (single instance)
l

mg/
PNEC 44.6 l aquatic organisms sewage treatment plant (STP) short-term (single instance)
PNEC 0.334 mg/ aquatic organisms freshwater sediment short-term (single instance)
kg

PNEC 0.033 mg/kg aquatic organisms marine sediment short-term (single instance)
mg/
PNEC 0.042 kg terrestrial organisms soil short-term (single instance)

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Version number: GHS 1.0 Date of compilation: 2017-06-05

8.2 Exposure controls

Appropriate engineering controls
General ventilation.
Individual protection measures (personal protective equipment)
Eye/face protection
Wear eye/face protection.
Skin protection
- Hand protection
In the case of wanting to use the gloves again, clean them before taking off and air them well.
- Other protection measures
Take recovery periods for skin regeneration. Preventive skin protection (barrier creams/ointments) is recommended. Wash
hands thoroughly after handling.
Respiratory protection
In case of inadequate ventilation wear respiratory protection.
Environmental exposure controls
Use appropriate container to avoid environmental contamination. Keep away from drains, surface and ground water.

SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties
Appearance

Physical state solid Crystaline.

Color Colourless or White.

Odor Irritant, Acre, Asphyxiant.

Other safety parameters

pH (value) not applicable

Melting point/freezing point 53 °C

Initial boiling point and boiling range 200.1 °C at 1,014 hPa

Flash point 103 °C

Evaporation rate not determined

Flammability (solid, gas) this material is combustible, but will not ignite readily

Lower explosion limit (LEL) 57 g/m³ , 1.4%.

Upper explosion limit (UEL) 290 g/m³ , 7.1%.

Vapor pressure 15.1 Pa at 22 °C

Density 0.93 g/cm³ at 20 °C

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Vapor density this information is not available

Solubility(ies)

- Water solubility 400 g/l at 20 °C

Partition coefficient

- n-octanol/water (log KOW) -2.61 (19.8 °C) (ECHA)

- Soil organic carbon/water (log KOC) 1.624 (ECHA)

Auto-ignition temperature not determined

Decomposition temperature 290 °C (ECHA)

Viscosity not relevant (solid matter)

Explosive properties none

Oxidizing properties none

9.2 Other information

SECTION 10: Stability and reactivity

10.1 Reactivity
Strong oxidizing agents (perchlorates, peroxides, chromates, sodium hypochlorite) - may react violently or explosively.
Increased risk of fire and explosion.
Water: reacts slowly with cold water, quickly with hot water, producing heat. It forms maleic acid. Warm water may cause foam. .

10.2 Chemical stability

See below "Conditions to avoid".

10.3 Possibility of hazardous reactions

No known hazardous reactions.

10.4 Conditions to avoid

Metals of alkali (sodium or potassium), alkalis (eg sodium hydroxide or potassium hydroxide), alkaline earth metals, (Calcium,
magnesium or barium), alkaline earth hydroxides (calcium hydroxide), amines (eg dimethylamine, triethylamine), pyridine,
Quinoline, sodium or potassium carbonates, aqueous ammonia, ammonium hydroxide or ammonium salts-at temperatures over
150 DEG c, mixtures can react to produce carbon dioxide, heat and pressure. Under these conditions, a mixture can be explos-
ive. Small amounts as low as 200 ppm of the above chemicals are sufficient to begin decomposition.
Olefins (eg, ethylene, propylene or diethylene) and the catalyst mixtures may be subjected to a copolymerization uncontrolled.
Strong reducing agents (eg, phosphorus, tin (II) chloride, metal hydrides) may react vigorously or violently. Increased risk of fire.
Alcohols-react to the esters of the form.
Static load, sparks, heat, other sources of ignition, generation of dust and moisture.

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Hints to prevent fire or explosion

The product in the delivered form is not dust explosion capable; the enrichment of fine dust however leads to the danger of dust
explosion.

10.5 Incompatible materials

Oxidizers

10.6 Hazardous decomposition products

Reasonably anticipated hazardous decomposition products produced as a result of use, storage, spill and heating are not
known. Hazardous combustion products: see section 5.

SECTION 11: Toxicological information

11.1 Information on toxicological effects
Classification acc. to GHS
Acute toxicity
Harmful if swallowed. May be harmful in contact with skin.

- Acute toxicity estimate (ATE)

Oral 1,090 mg/kg
Dermal 2,620 mg/kg

Skin corrosion/irritation
Causes severe skin burns and eye damage.
Serious eye damage/eye irritation
Causes serious eye damage.
Respiratory or skin sensitization
May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.
Germ cell mutagenicity
Shall not be classified as germ cell mutagenic.
Carcinogenicity
Shall not be classified as carcinogenic.
Reproductive toxicity
Shall not be classified as a reproductive toxicant.
Specific target organ toxicity - single exposure
Shall not be classified as a specific target organ toxicant (single exposure).
Specific target organ toxicity - repeated exposure
Causes damage to organs through prolonged or repeated exposure.
Aspiration hazard
Shall not be classified as presenting an aspiration hazard.

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SECTION 12: Ecological information

12.1 Toxicity
Harmful to aquatic life.

Aquatic toxicity (acute)

Endpoint Value Species Exposure time

LC50 75 mg/l fish 96 h

mg
EC50 42.81 /l aquatic invertebrates 48 h

ErC50 74.35 mg/l algae 72 h

12.2 Persistence and degradability

Data are not available.

12.3 Bioaccumulative potential

Data are not available.

n-octanol/water (log KOW) -2.61 (19.8 °C) (ECHA)

12.4 Mobility in soil

Data are not available.

Henry's law constant 0 Pa m³/mol at 25 °C

The Organic Carbon normalised adsorption 1.624 (ECHA)

coefficient

12.5 Results of PBT and vPvB assessment

Data are not available.

12.6 Other adverse effects

Data are not available.

SECTION 13: Disposal considerations

13.1 Waste treatment methods
Sewage disposal-relevant information
Do not empty into drains. Avoid release to the environment. Refer to special instructions/safety data sheets.
Waste treatment of containers/packages
Only packagings which are approved (e.g. acc. to the Dangerous Goods Regulations) may be used. Completely emptied pack-
ages can be recycled. Handle contaminated packages in the same way as the substance itself.

Remarks
Please consider the relevant national or regional provisions. Waste shall be separated into the categories that can be handled
separately by the local or national waste management facilities.

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SECTION 14: Transport information

14.1 UN number 2215
14.2 UN proper shipping name MALEIC ANHYDRIDE
14.3 Transport hazard class(es)
Class 8 (corrosive substances)
14.4 Packing group III (substance presenting low danger)
14.5 Environmental hazards non-environmentally hazardous acc. to the dangerous
goods regulations
14.6 Special precautions for user
There is no additional information.

14.7 Transport in bulk according to Annex II of MARPOL and the IBC Code
The cargo is not intended to be carried in bulk.

Information for each of the UN Model Regulations

Transport information - National regulations - Additional information (UN RTDG)
UN number 2215
Proper shipping name MALEIC ANHYDRIDE
Class 8
Packing group III
Danger label(s) 8

Special provisions (SP) - (UN RTDG)

Excepted quantities (EQ) E0 (UN RTDG)
Limited quantities (LQ) 0 (UN RTDG)
International Maritime Dangerous Goods Code (IMDG)
UN number 2215
Proper shipping name MALEIC ANHYDRIDE
Class 8
Packing group III
Danger label(s) 8

Special provisions (SP) -

Excepted quantities (EQ) E0
Limited quantities (LQ) 0
EmS F-A, S-B
Stowage category A

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Segregation group 1 - Acids

International Civil Aviation Organization (ICAO-IATA/DGR)
UN number 2215
Proper shipping name Maleic anhydride
Class 8
Packing group III
Danger label(s) 8

Excepted quantities (EQ) E1

Limited quantities (LQ) 5 kg

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question
There is no additional information.
National regulations (United States)
Toxic Substance Control Act (TSCA) substance is listed
SARA TITLE III (Superfund Amendment and Reauthorization Act)
- List of Extremely Hazardous Substances (40 CFR 355) (EPCRA Section 302 and 304)
not listed
- Specific Toxic Chemical Listings (40 CFR 372) (EPCRA Section 313)

Toxics Release Inventory: Specific Toxic Chemical Listings

Name acc. to inventory CAS No Remarks Effective date

maleic anhydride 108-31-6 1986-12-31

CERCLA (Comprehensive Environmental Response, Compensation, and Liability Act)

- Section 102(A) Hazardous Substances (40 CFR 302.4)

Name of substance CAS No Remarks Statutory Final RQ pounds

code (Kg)

maleic anhydride 108-31-6 1 5000 (2270)

3
4
Legend
1 "1" indicates that the statutory source is section 311(b)(2) of the Clean Water Act
3 "3" indicates that the source is section 112 of the Clean Air Act
4 "4" indicates that the source is section 3001 of the Resource Conservation and Recovery Act (RCRA)

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Clean Air Act

not listed
New Jersey Worker and Community Right to Know Act N.J.S.A. 34:5A-1 et. seq.

Right to Know Hazardous Substance List

Name acc. to inventory CAS No Remarks Classifications

maleic anhydride 108-31-6 CO

R1
Legend
CO Corrosive
R1 Reactive - First Degree

California Environmental Protection Agency (Cal/EPA): Proposition 65 Chemicals known to the

State to cause cancer or reproductive toxicity
not listed

15.2 Chemical Safety Assessment

No Chemical Safety Assessment has been carried out for this substance.

SECTION 16: Other information, including date of preparation or last revision

Abbreviations and acronyms

Abbr. Descriptions of used abbreviations

CAS Chemical Abstracts Service (service that maintains the most comprehensive list of chemical substances)
DGR Dangerous Goods Regulations (see IATA/DGR)

DNEL Derived No-Effect Level

EmS Emergency Schedule

GHS "Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Nations
IATA International Air Transport Association

IATA/DGR Dangerous Goods Regulations (DGR) for the air transport (IATA)
ICAO International Civil Aviation Organization

IMDG International Maritime Dangerous Goods Code

MARPOL International Convention for the Prevention of Pollution from Ships (abbr. of "Marine Pollutant")

NOM-010-STPS NORMA Oficial Mexicana NOM-010-STPS: Agentes químicos contaminantes del ambiente laboral-Reconocimi-
ento, evaluación y control
PBT Persistent, Bioaccumulative and Toxic

PNEC Predicted No-Effect Concentration

ppm Parts per million

STEL Short-term exposure limit

TWA Time-weighted average

VLE Permissible exposure limit

vPvB Very Persistent and very Bioaccumulative

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Key literature references and sources for data

Norma Oficial Mexicana NOM-018-STPS-2015, Sistema armonizado para la identificación y comunicación de peligros y riesgos
por sustancias químicas peligrosas en los centros de trabajo y NMX-R-019-SCFI-2011 Sistema Armonizado de Clasificación y
Comunicación de Peligros de los Productos Químicos.
.
UN Recommendations on the Transport of Dangerous Good. International Maritime Dangerous Goods Code (IMDG).
Dangerous Goods Regulations (DGR) for the air transport (IATA).

List of relevant phrases (code and full text as stated in chapter 2 and 3)

Code Text

H302 Harmful if swallowed.

H313 May be harmful in contact with skin.

H314 Causes severe skin burns and eye damage.

H317 May cause an allergic skin reaction.

H318 Causes serious eye damage.

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.

H372 Causes damage to organs through prolonged or repeated exposure.

H402 Harmful to aquatic life.

Disclaimer
THIS INFORMATION IS BASED UPON CALCULATED DATA. THE COMPANY HAS NO LIABILITY FOR DAMAGES
SUFFERED BY THE PURCHASER OR OTHER PERSONS IN HANDLING OF THESE MATERIALS IF SAFETY INSTRUC-
TIONS WERE NOT FOLLOWED. THE COMPANY HAS NO LIABILITY FOR MISUSE OF THIS MATERIAL, EVEN IF THE
SAFETY INSTRUCTIONS WERE FOLLOWED. PURCHASER IS RESPONSIBLE FOR THE USE OF THIS MATERIAL. THIS
SAFETY DATA SHEET IS PREPARED IN ACCORDANCE WITH THE GUIDELINES OF THE CURRENT MEXICAN OFFICIAL
STANDARD.CONFIDENTIAL INFORMATION ABOUT THE COMPOSITION WAS OMITTED.

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