Rajivgandhi University of Health Sciences, Karnataka: 1. Name of The Candidate and Address
Rajivgandhi University of Health Sciences, Karnataka: 1. Name of The Candidate and Address
Rajivgandhi University of Health Sciences, Karnataka: 1. Name of The Candidate and Address
SCIENCES, KARNATAKA
FOR DISSERTATION
OF NURSING,
MUNNEKOLALA,
MARATHAHALLI,
BANGALORE-560037.
Nursing.
1
3. Course of study and subject M.Sc Nursing I year,
6.0 INTRODUCTION
“Diseases can rarely be eliminated through early diagnosis or good treatment but
2
- DENIS BURKITT
A patient is any person who receives medical attention, care or treatment. There are a
number of problems that effect patients who have to spend prolonged periods in bed. This list
is not exhaustive but the most frequently uncounted problems includes muscle spasm,
The vascular system is vast network of vessels through which blood circulates in the
body. Arteries, arterioles, veins, venules, capillaries and lymphatic constitute the structural
elements of vascular system. Approximately 75% of total blood volume is contained in the
veins. Venous disorders are characterized by stasis, hypercoagulability of the blood and
Deep vein thrombosis (DVT) is a condition in which a blood clot (a blockage) forms
in a deep vein. While these clots most commonly occur in the veins of the leg (the calf or
thigh), they can also develop in other parts of the body. DVT can be very dangerous and is
considered a medical emergency. If the clot (also known as a thrombus) breaks loose and
travels through the bloodstream, it can lodge in the lung. This blockage in the lung, called a
pulmonary embolism, can make it difficult to breathe and may even cause death.8,10,11
3
In the past decade, deep vein thrombosis has increasingly been recognized as an
important and possibly preventable cause of morbidity and mortality in hospitalized patients.
Understanding the natural history of venous thrombosis is important for optimal management
of this condition. Once risk factors are recognized it is possible to avoid these risk factors or
There are several factors that increase the risk of developing Deep vein thrombosis. It
includes major surgeries, immobility, recent injury, certain chronic medical illness such as
stroke, paraplegia, heart diseases, and cancer, pregnancy, increased estrogen, certain
All hospitalized patients should be assessed for clinical risk factors of DVT . The risk
is in surgical and orthopedic patients .Medical patients are also at high risk and should
receive thromboprophylaxis . Nurses can encourage mobilization and leg exercises in at-risk
patients in order to activate the calf muscle pump. Breathing exercises will also help venous
return. Patients should be advised to observe for signs and symptoms that suggest DVT and
Every year Deep vein thrombosis occurs in about 1 in 3000 in those below the age of
40 and 1 in 500 in those over 80years of age. A world wide survey conducted by WHO
showed that Deep vein thrombosis is a common disease with an average incidence
rate of more than one per 1000. Deep vein thrombosis is also a lethal disease mostly owing to
4
Pulmonary embolism. Survivors may experience serious and costly long term
complications.16
An estimated 300,000 individuals are hospitalized annually in the United States for
deep vein thrombosis (DVT) disease. This is especially significant, as up to three quarters of
cases of DVT disease remain silent and do not come to medical attention. The overall
Pulmonary embolism is estimated to be responsible for about 150,000 deaths per year
acute pulmonary emboli. In Canada, it is reported that Pulmonary embolism from Deep vein
thrombosis causes death of more than 1,00,000 patients each year. It remains a leading
Deep vein thrombosis and pulmonary embolism are the major health problems with
two possible serious outcomes. Pulmonary embolism can be fatal. Deep vein thrombosis can
lead to chronic venous insufficiency and affect the ‘Quality of life’ and at the same time
increase the cost of patient’s management. Epidemiological data indicate that annual
frequency in general population is approximately 160 per 100,000 for Deep vein thrombosis
Deep vein thrombosis is a common preventable cause of death; especially who are
considered as high risk for Deep vein thrombosis like Orthopedic, Stroke, Cardiology
5
patients are identified and preventive measures are instituted without delay.
Systematic assessment, early detection, physical and pharmacological prophylaxis are some
Nursing is a balanced art of compassion and science of concern .When science gives
up the art takes over the disease. Nurses should focus on prevention by the early recognition
and adequate prophylaxis of those at increased risk. Patients should be actively involved in
their care wherever possible. An awareness of diagnostic and treatment strategies will enable
nurses to inform patients. This will help to improve both concordance with treatment and
disease outcome. The nurse can observe and assess how the patient is managing her or his
The goals of this study are to promote health, to preserve health, to minimize
suffering and distress of the high risk patients. These goals are embodied in the word
prophylactic or early detection and treatment are the main intervention of disease control.
Deep vein thrombosis is more serious because it presents a greater risk for
hospital are at increased risk of DVT, and it is therefore important for nurses to
6
High risk for developing deep vein thrombosis is found in patients with the
and trauma (40-60%). The five most frequent co-morbidities were hypertention
obesity(27%).4,18
syndrome and death. Approximately 200,000 individuals die annually as result of PE.
Recurrences of VTE account for the minority of causes of deaths. Approximately 25% of
DVT patients remain asymptomatic in the long term but severe signs of post-thrombotic
showed that 70% of acute hospital trusts are now taking steps to risk assess patients for
hospital-acquired Deep vein thrombosis-compared with only 32% in their 2007 report.
These finding demonstrate that more hospitals are now bringing their practices in line.
The majority (74%) of hospital-acquired Deep vein thrombosis cause symptoms after the
patient has left hospital. Hospital-acquired Deep vein thrombosis occur in up to 50% of
patients undergoing major orthopedic surgery who do not receive preventive care.17
World statistics revealed that 25% to 40% of patients over the age of
40years,operated for one or more hours develop Deep vein thrombosis. Therefore
7
practice of preventive measures is needed. Deep vein thrombosis is a complication and
major source of morbidity and mortality in healthy patients above 40years of age
undergoing extensive elective surgery like arthroplasty and cardiac surgeries and cardiac
Many healthcare providers are under the false impression that this life-
threatening illness is not a problem in their hospital or among their patients. While it is
true that an individual doctor will normally see relatively few patients with this disease, it
is clear that DVT is an important public health problem. Each year, 600,000 patients
experience venous thromboembolism. Each year, at least 50,000 and perhaps as many as
200,000 patients die from blood clots that obstruct blood flow to their lungs (pulmonary
measures. Use of modern methods of DVT prophylaxis will reduce the incidence of DVT
during the postoperative period by two-thirds and will prevent death from pulmonary
388 cases between 1996-97,Asian countries 6-75%. Epidemiology indicates that DVT or
PE may occur in almost 2 in 1,000 people each year, with up to 25% of those having a
recurrence. Around 5-15% of people with untreated DVT may die from PE. Male: female
ratio = 1.2 to 1. When not pregnant or using oral contraceptives or HRT, women have a
lower risk than men. Two thirds of patients with proven PE have no symptoms of DVT
8
and, in one third of cases, it is impossible to find the original site of a DVT without an
autopsy. Autopsy studies demonstrate that approximately 80% of all cases of DVT and
PE remain undiagnosed, even when they are the immediate cause of death.14
Prognosis indicates there may well be recurrence of DVT. Recurrence after the
first event can be as high as 60% but halved by compression stockings. Death occurs in
Incidences of DVT in South India (Vellore) revealed that post operative DVT is a well
recognized complication. The reported incidence ranges from 45% to 85% in patients who
have had no prophylaxis. DVT was determined in 50% of patient aged 50years and more. In
patients with malignancy the incidence was 47.6%; 10% had an infusion in to ankle during
operation and three of them developed venous thrombosis in the same day.20
About 80 cases per 100,000 persons annually diagnosed as deep vein thrombosis in world
wide. 600,000 hospitalizations for deep vein thrombosis occur annually in the United States.
200,000 deaths annually in the United States due to pulmonary embolism attributed by deep
vein thrombosis. 80% of pulmonary embolism occurs without signs. 2/3 rd of deaths occur
within 30 minutes due to pulmonary embolism. Variable incidences (20 – 70%) of deep
venous thrombosis in hospitalized patients. Venous alteration and venous insufficiency of the
lower leg, which are long term complications of DVT, affect 0.5% of the entire population.
patient in hospital. If the patient develop complication of DVT, then the cost of
9
management steeply increases. Venous ulcers develop in at least 300 per 100,000
injuries, traction and plaster cast reduces movement and enforce rest and immobility. All
these factors lead to venous stasis and an increased likelihood of thrombosis. It was
stocking., would enable the patient to prevent development of Deep vein thrombosis.12,13
Deep vein thrombosis is a serious problem that affects millions of people annually.
Prophylaxis against DVT can save lives. Proper application of the prophylactic regimen by
nursing and the interdisciplinary team can be a major key in affecting the outcome of the
high risk patient. To obtain successful outcome, the educational needs of each individual in
interdisciplinary team must be met, also the practice pattern and implementing individual
hospitals of Tabria. The result revealed that highest rate of DVT prevention was related to
wards(0%).21
10
A descriptive study was conducted among 159 registered nurses to evaluate the
knowledge level of registered nurse on DVT. The result revealed that there was a significant
relationship between longer years of work experience and the RNs' level of DVT knowledge
levels and area of specialized and non-specialized trained RNs' were found to be
insignificant.22
could be reduced by patient awareness and nursing staff concern with exercise, post-
operative circle-bed turning and use of the Trendelenburg position form the foundation of
prophylaxis of DVT.18
Preventions is better than cure –Having identified patients at high risk of DVT, the
nurses select the most appropriate prophylactic measures. Early mobilization of patients, as
soon as possible after surgery is to reduce the chance of DVT. Graded compression stocking
have been shown to be effective introducing post operative venous thrombosis. Hospital-
acquired deep vein thrombosis (DVT) and pulmonary embolisms (PE) are preventable
problems that can increase mortality. Early assessment and recognition of risk as well as
Nurses are the professionals who deals with patients round the clock and have
adequate knowledge and skill to be competent. DVT is an early preventable but not
ortho and neuron patients. By concentrating on the above statistics and factors the
11
investigator decided to conduct study on assessment of knowledge and practice of staff
nurses regarding prevention of Deep vein thrombosis among high risk hospitalized client.
DVT is a blood cloat that develop in a deep vein usually in the leg.
Venous stasis
12
RISK FACTORS FOR DEEP VEIN THROMBOSIS:-
1)VENOUS STASIS
Advanced age
Atrial fibrillation
Obesity
Orthopedic surgery
Postpartum period
Pregnancy
Prolonged immobility such as bed rest, fractured leg or hip, long trips without adequate
Stroke
Varicose vein
2)ENDOTHELIAL DAMAGE
3)HYPERCOAGULABILITY OF BLOOD
13
Cigarette smoking
Dehydration or malnutrition
Nephrotic syndrome
Malignancies
Oral contraceptives
Pregnancy
Sepsis
CLINICAL MANIFESTATION:-
Extrimity pain
Warm skin
Erythema
Tenderness on palpation
DIAGNOSTIC STUDIES:-
Blood laboratory studies include ACT, a PTT ,bleeding time, Hb, INR ,platelet count,
D-dimer testing
14
Venogram
Early mobilization
Positioning
Rotation of ankles
MANAGEMENT:-
Anticoagulant
1.Vitamin K antagonist
2.Unfractionated heparin
5.Factor Xa inhibitor
Venous thrombectomy
COMPLICATION:-
Pulmonary embolism
PTS
15
STUDIES RELATED TO KNOWLEDGE AND PRACTICE OF STAFF NURSES
thrombosis among 50 patients in South India at a tertiary care hospital. The result
revealed that Most of our patients were male (56%), in age group between
20-40 years. Pain with limb swelling (64.5%) were the most common presenting
symptoms in limb DVT and 9 patients (28.1%) had symptoms of PE. 28% patients
presented with recurrence of venous thrombosis. 78% patients with symptomatic limb
.DVT had involvement of the proximal veins. 34% patients had no evidence of acquired
risk factors, while 66% of patients had one or more acquired risk factors. 14 % had high
serum homocysteine (>15µmol/L) and 12% were positive for APLA test. Among 35
patients, protein C deficiency in 22.9% patients and protein S deficiency in 20% patients
were identified. Among 15 patients anti-thrombin III deficiency was present in 26.7%,
Factor V Leiden mutation in 20% patients and high factor VIII level in 6.7% patients.
thrombosed vein in 45.8%, and partial recanalisation in 54.11%. There was no correlation
between the outcome, i.e. Doppler normalization Sand the duration of symptoms.23
A study conducted to evaluate the effectiveness of an intervention targeting both
France.The result showed that one department to the intervention targeted at physicians
only and 7 departments allocated to the intervention targeted at both physicians and
nurses dropped out of the study.Compared with the intervention targeted at physicians
16
only (n=497 patients),the intervention targeted at both physicians and nurses (n=315
patients) was associated with a higher rate of mobilization and comparable levels of
elastic stockings and anticoagulant use.The rates of deep vein thrombosis ,bleeding and
patients admitted in a tertiary care hospital at Bangalore. The result revealed that the
mean age of the study group was 34 to 96yrs ranging from 18 to 75yrs.Out of the 50
patients,28 were male and 22 were female .The mean age of male and female was
37.43yrs and 31.25 yrs respectively.38 patients resided in Karnataka,7 patients were
embolism in U.S. The result showed that the number of patients who are at risk for
continue to increase in the years to come due to aging of the population, increasing
number of orthopedic procedures performed each year, and increasing prevalence of heart
rate, stroke, and other acute medical illness that place patients at risk for venous thrombo
embolism.26
A study was conducted to determine deep vein thrombosis following ischemic
stroke among Asians. The result revealed that deep vein thrombosis was detected in 30%
of patients at days 7-10 and in 45% of patients at days 25-30.Most thrombosis were
significant associations of age and degree of weakness with the presence of deep vein
17
thrombosis at days 25-30, but not at days 7-10.Deep vein thrombosis in the 1 st month
A study was conducted to evaluate the effectiveness of structured teaching
lower extrimities in selected hospital at Bangalore.The findings revealed that the mean
post test practice score of 24.96 of the mean pre test practice score of 10.66 and was
significant . There exists a significant association between pretest knowledge score and
A prospective randomized study carried out in 104 Indian patients undergoing
venographically proved deep vein thrombosis, the distribution of the thrombi and their
prophylactically with LMWH showed a 43.2% incidence of deep vein thrombosis. Group
postoperatively. The incidence was high in patients undergoing total knee arthroplasty.
Majority of the thrombi were distal, involving a short segment of the ipsilateral leg.
Clinical signs and symptoms proved unreliable for diagnosing this condition.29
A study was conducted to evaluate effectiveness of self instructional module for
patients at selected hospital at Mangalore.The finding of the study revealed that the
difference between mean pretest knowledge score(13.2) and mean post test knowledge
18
score (26.98)was found to be statistically significant p<0.001,suggesting that SIM was
physical prophylaxis can be given to mobilize the muscles and the circulation.One among
stocking.31
A randomized control study was conducted to evaluate the effect of sequentional
foot compression on prevention of VTE after total knee arthroplasty among 48 patients
in India.The result revealed that lower limb swelling and pain were significantly VTE in
A study stated that Venous thromboembolism is a common disease among
hospitalized patients with an average annual incidence of over one per 1000.These are
10% to 30% of surgical ICU who developed DVT with the 1 st week of admission.The
in spinal cord injury patients is in the range of 50% to 80%.To improve the survival rate
19
6.3 PROBLEM STATEMENT
Deep Vein Thrombosis among high risk hospitalized clients in selected hospital at
Bangalore.
6.4 OBJECTIVES
1)To assess the knowledge of staff nurses regarding prevention of DVT among high risk
hospitalized clients.
2)To identify the practice of staff nurses regarding prevention of DVT among high risk
hospitalized clients.
demographic variables.
6.5 HYPOTHESIS
regarding prevention of deep vein thrombosis among high risk hospitalized clients.
20
ASSESSMENT: It is a process of measuring the level of knowledge and
structured questionnaire.
STAFF NURSES: Nurses who have completed Diploma or B.Sc Nursing and
immobilized.
6.7 ASSUMPTION
Staff nurses will have some knowledge and practice regarding prevention of
21
Level of knowledge of staff nurse varies based on their period of experiences
7.1 SOURCE OF DATA: The staff nurses who are working in orthopedic and neurological
technique.
interview technique for assessing practice will be used to collect data. The duration of the
structured questionnaire to determine the level of knowledge and practice of staff nurses
22
RESEARCH DESIGN: It is non-experimental descriptive design using structured
questionnaire to find out the level of knowledge and practice of staff nurses regarding
SAMPLING TECHNIQUE: The sample of 50 staff nurses will be selected using non
questionnaire. Verbal consent will be taken from the sample prior to the study.
SAMPLE AND SAMPLE SIZE: The sample of 50 staff nurses in selected hospitals at
Bangalore.
SETTING OF THE STUDY: The descriptive cross sectional study will be conducted in
INCLUSION CRITERIA:
EXCLUSION CRITERIA:
23
7.2.2 DATA COLLECTION TOOL: A structured questionnaire will be used to determine
the level of knowledge and practice of staff nurses in a selected hospital at Bangalore.
prevention of DVT.
VALIDITY: The structured questionnaire will be prepared to assess the level of knowledge
and practice of staff nurse. The validity of the tool will be done in consultation with guide
7.2.3 DATA ANALYSIS METHODS: Data analysis can be done by descriptive inferential
statistics. The descriptive statistics like frequency distribution, table, mean and standard
deviation to see the association between knowledge and socio demographic variables and
No, the study does not require any investigation to be conducted on the patient / other
24
7.4 HAS ETHICAL CLEARANCE BEEN OBTAINED?
Yes, the confidentiality and anonymity of the subject will be maintained. Concern
8.0 REFERENCE
3. http://www.cdc.gov/features/thrombosis/
4. http://www.ncbi.nih.gov/pubmed/14715365
5. http://www.medicalnewstoday.com/articles/B1624.php
6. http://www.medicalnewstoday.com/articles/10872.php
7. http://content.karger.com/produckte
10. Lewis S.M et.al, “Medical Surgical Nursing”, 6th edition, 2004, Mosby’s
25
11. Suzanee C.S, Brenda G.B, “Textbook of Medical Surgical Nursing”, 10th edition,
12. http://www.uni-duesseldorf.de/
13. www.thrombosisadviser.com
15. http://www.medscape.com/viewarticles/590272-3
16. http://www.who.int.com
17. 2nd annual report of the All Party Parliamentary Thrombosis Groups (APPTG)
18. http://www.dvt.org
http://www.3.interscience.wiley.com/journal/112197402/
21. Aydin Pirzeh et.al, Practice of DVT prophylaxis in teaching hospitals, Tabria,
2003
22. Asma Ahamd et.al, Study on assessment of the knowledge regarding DVT among
23. Vijay Kumar J.R, Assessment of the factors predisposing to thrombosis, South
India, 2008
25. Dr. Santhosh R, Study on DVT profile of patients in tertiary care hospital and risk
analysis,Bangalore,2007.
26
26. Anderson.F.A et.al, Study on acute- care hospital patients at risk for venous
thromboembolism,U.K ,2007
27. Deidre Anne De Silva et.al, Study on DVT following ischemic stroke,Asia,2006
30. Renju Joe, Effectiveness of self instructional module for staff nurses on
31. Nesurker, DVT is the frequent morbidity and mortality in surgical patients,2002.
27
9 SIGNATURE OF CANDIDATE
11.1 GUIDE
11.2 SIGNATURE
11.3 CO-GUIDE
28
11.4 SIGNATURE
DEPARTMENT
11.6 SIGNATURE
CHAIRMAN AND
PRINCIPAL
12.2 SIGNATURE
29