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DrugStudy Metformin

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Ateneo de Davao University CRITERIA

E. Jacinto Street, 8016


Content: 35% ____
Davao City
Nursing Responsibilities: 35% ____
Picture: 10% ____
Format: 5% ____
Name of Student: Ashknee Khainna A. Alejo Course/Year/Section: BSN 2B Subject: NCM 2144/ Pharmacology Date: 09-23- 2020 Promptness: 5% ____
Reference: 10% ____

DRUG STUDY FORM

Drug Name Classification Mechanism of Action Side Effects/ Nursing Responsibilities/


Adverse Effects Patient and Family Health Teachings

Generic Name Pharmacotherapeutic It improves the glycemic control of the SE: 1. Tell the patient that Metformin helps in controlling
Metformin Class: body by decreasing the hepatic (Occasional) Diarrhea, nausea, hyperglycemia and does not cure diabetes therefore, the
Biguanide production of glucose. It also vomiting, abdominal bloating, therapy is usually for long term.
Antihyperglycemic. decreases the intestinal absorption of flatulence, anorexia (Rare) R: To enhance patient knowledge about the medication
Brand Name glucose and improves insulin Unpleasant/metallic taste that
Glucophage sensitivity, stabilizes body weight and
Clinical Class: resolves spontaneously during 2. Ask the patient to report discomfort such as sore throat, fever,
improves lipid profile.
Antidiabetic Agent. therapy. rash, dark urine or light colored stools.
R: These signs and symptoms are manifestations of possible
AE: side effects of the medication
Lactic acidosis which may progress
to cardiovascular collapse (shock), 3. Instruct the patient to report chills, diarrhea, dizziness, low BP,
acute HF, acute MI, or prerenal muscle pain, sleepiness, abdominal pains, nausea and
azotemia. vomiting anorexia.
R: These are signs and symptoms of increased risk of lactic
acidosis.

4. Assess for hepatic impairment or advanced cirrhosis.


R: Advanced cirrhosis heightens the risk of developing lactic
acidosis.
Drawing/ Picture Indication Pharmacokinetics Pharmacodynamics 5. Assess for renal function before initiating the medication.
Discontinue if renal impairment occurs.
R: Metformin is contraindicated for patients with renal
Oral Absorption PO
impairment due to concerns of lactic acidosis.
It is indicated for the It is slowly and incompletely absorbed Onset: Less that 1 hr
management of type 2 after PO administration. Its absorption Peak: 1-3 hr
6. Monitor serum glucose and glycosylated hemoglobin
diabetes mellitus. may also be allowed due to food Duration: 24 hr
periodically during therapy
delays.
R: To evaluate effectiveness of therapy.

Distribution
7. Encourage patient to follow prescribed diet, medication, and
PB: Negligible
exercise regimen
R: To promote patient wellness and prevent hyperglycemic or
Metabolism
hypoglycemic episodes
t ½: 1.5-5 hr

8. Counsel female patients to notify health care professional if


Excretion
breastfeeding
It is primarily excreted in the urine and
R: Metformin may pass into breast milk in very small
can also be removed from the body
quantities.
through hemodialysis.

9. Monitor serum folic acid and vitamin B12 every 1 to 2 years in


long-term therapy
R: Metformin therapy may deplete vitamin B12 and folic acid
in the body.

10. Emphasize the importance of attending follow-up exams and


regular testing of blood glucose, glycosylated hemoglobin,
renal function, and hematologic parameters.
R: To closely monitor the changes in the condition of the
patient.
References:
Kee, MS, RN, Hayes, PhD, MPH, FNP-BC; McCuistion PhD, RN, CNS . (2015.). Pharmacology: A Patient-Centered Nursing Process Action (8th ed.).
Kizior, R., BS, RPh, & Hodgson, K., RN, BSN, CCRN. (2019). Saunders Nursing Drug Handbook 2019. Elsevier.
Lilley, RN, PhD, Collins,PharmD & Snyder , MSN, RN-BC. (2007). PHARMACOLOGY AND THE NURSING PROCESS (7th ed.). Elsevier Mosby.

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