Material Safety Data Sheet

Genetron AZ-50 (R-507)

1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME: Genetron AZ-50 (R-507)

OTHER/GENERIC NAMES: R-125, HFC-125
PRODUCT USE: Refrigerant
MANUFACTURER: Honeywell
101 Columbia Road
Box 1053
Morristown, New Jersey 07962-1053

FOR MORE INFORMATION CALL: IN CASE OF EMERGENCY CALL:

(Monday-Friday, 9:00am-5:00pm) (24 Hours/Day, 7 Days/Week)
1-800-522-8001 1-800-707-4555 or Chemtrec 1-800-424-9300

2. COMPOSITION/INFORMATION ON INGREDIENTS

INGREDIENT NAME CAS NUMBER WEIGHT %

Pentafluoroethane 354-33-6 50
1,1,1-Trifluoroethane 420-46-2 50

Trace impurities and additional material names not listed above may also appear in Section 15 toward the end of the MSDS.
These materials may be listed for local "Right-To-Know" compliance and for other reasons.

3. HAZARDS IDENTIFICATION

EMERGENCY OVERVIEW: Colorless, volatile liquid with ethereal and faint sweetish odor. Non-flammable
material. Overexposure may cause dizziness and loss of concentration. At higher levels, CNS depression and
cardiac arrhythmia may result from exposure. Vapors displace air and can cause asphyxiation in confined
spaces. At higher temperatures, (>250°°C), decomposition products may include Hydrofluoric Acid (HF) and
carbonyl halides

POTENTIAL HEALTH HAZARDS

SKIN: Irritation would result from a defatting action on tissue. Liquid contact could cause frostbite.

EYES: Liquid contact can cause severe irritation and frostbite. Mist may irritate.

INHALATION: Genetron AZ-50 (R-507) is low in acute toxicity in animals. When oxygen levels in air are reduced to
12–14% by displacement, symptoms of asphyxiation, loss of coordination, increased pulse rate and
deeper respiration will occur. At high levels, cardiac arrhythmia may occur.

INGESTION: Ingestion is unlikely because of the low boiling point of the material. Should it occur, discomfort in the
gastrointestinal tract from rapid evaporation of the material and consequent evolution of gas would result.
Some effects of inhalation and skin exposure would be expected.

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Current Issue Date: February, 2003
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Genetron AZ-50 (R-507)

DELAYED EFFECTS: None known

Ingredients found on one of the OSHA designated carcinogen lists are listed below.

INGREDIENT NAME NTP STATUS IARC STATUS OSHA LIST

No ingredients listed in this section

4. FIRST AID MEASURES

SKIN: Promptly flush skin with water until all chemical is removed. If there is evidence of frostbite, bathe (do not rub) with
lukewarm (not hot) water. If water is not available, cover with a clean, soft cloth or similar covering. Get medical
attention if symptoms persist.

EYES: Immediately flush eyes with large amounts of water for at least 15 minutes (in case of frostbite water should be
lukewarm, not hot) lifting eyelids occasionally to facilitate irrigation. Get medical attention if symptoms persist.

INHALATION: Immediately remove to fresh air. If breathing has stopped, give artificial respiration. Use oxygen as
required, provided a qualified operator is available. Get medical attention. Do not give epinephrine
(adrenaline).

INGESTION: Ingestion is unlikely because of the physical properties and is not expected to be hazardous. Do not induce
vomiting unless instructed to do so by a physician.

ADVICE TO PHYSICIAN: Because of the possible disturbances of cardiac rhythm, catecholamine drugs, such as
epinephrine, should be used with special caution and only in situations of emergency life
support. Treatment of overexposure should be directed at the control of symptoms and the
clinical conditions.

5. FIRE FIGHTING MEASURES

FLAMMABLE PROPERTIES

FLASH POINT: Gas, not applicable per DOT regulations

FLASH POINT METHOD: Not applicable
AUTOIGNITION TEMPERATURE: >750°C
UPPER FLAME LIMIT (volume % in air): None by ASTM E681
LOWER FLAME LIMIT (volume % in air): None by ASTM E681
FLAME PROPAGATION RATE (solids): Not applicable
OSHA FLAMMABILITY CLASS: Not applicable

EXTINGUISHING MEDIA:
Use any standard agent – choose the one most appropriate for type of surrounding fire (material itself is not flammable)

UNUSUAL FIRE AND EXPLOSION HAZARDS:

Genetron AZ-50 (R-507) is not flammable at ambient temperatures and atmospheric pressure. However, this material will
become combustible when mixed with air under pressure and exposed to strong ignition sources.
Contact with certain reactive metals may result in formation of explosive or exothermic reactions under specific conditions
(e.g. very high temperatures and/or appropriate pressures).

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Current Issue Date: February, 2003
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Genetron AZ-50 (R-507)

SPECIAL FIRE FIGHTING PRECAUTIONS/INSTRUCTIONS:

Firefighters should wear self-contained, NIOSH-approved breathing apparatus for protection against possible toxic
decomposition products. Proper eye and skin protection should be provided. Use water spray to keep fire-exposed
containers cool.

6. ACCIDENTAL RELEASE MEASURES

IN CASE OF SPILL OR OTHER RELEASE: (Always wear recommended personal protective equipment.)
Evacuate unprotected personnel. Protected personnel should remove ignition sources and shut off leak, if without risk, and
provide ventilation. Unprotected personnel should not return until air has been tested and determined safe, including low-
lying areas.

Spills and releases may have to be reported to Federal and/or local authorities. See Section 15 regarding reporting
requirements.

7. HANDLING AND STORAGE

NORMAL HANDLING: (Always wear recommended personal protective equipment.)

Avoid breathing vapors and liquid contact with eyes, skin or clothing. Do not puncture or drop cylinders, expose them to
open flame or excessive heat. Use authorized cylinders only. Follow standard safety precautions for handling and use of
compressed gas cylinders.

Genetron AZ-50 (R-507) should not be mixed with air above atmospheric pressure for leak testing or any other purpose.

STORAGE RECOMMENDATIONS:
Store in a cool, well-ventilated area of low fire risk and out of direct sunlight. Protect cylinder and its fittings from physical
damage. Storage in subsurface locations should be avoided. Close valve tightly after use and when empty.

8. EXPOSURE CONTROLS/PERSONAL PROTECTION

ENGINEERING CONTROLS:
Provide local ventilation at filling zones and areas where leakage is probable. Mechanical (general) ventilation may be
adequate for other operating and storage areas.

PERSONAL PROTECTIVE EQUIPMENT

SKIN PROTECTION:
Skin contact with refrigerant may cause frostbite. General work clothing and gloves (leather) should provide adequate
protection. If prolonged contact with the liquid or gas is anticipated, insulated gloves constructed of PVA, neoprene or
butyl rubber should be used. Any contaminated clothing should be promptly removed and washed before reuse.

EYE PROTECTION:
For normal conditions, wear safety glasses. Where there is reasonable probability of liquid contact, wear chemical safety
goggles.

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Current Issue Date: February, 2003
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Genetron AZ-50 (R-507)

RESPIRATORY PROTECTION:
None generally required for adequately ventilated work situations. For accidental release or non-ventilated situations, or
release into confined space, where the concentration may be above the PEL of 1,000 ppm, use a self-contained, NIOSH -
approved breathing apparatus or supplied air respirator. For escape: use the former or a NIOSH-approved gas mask
with organic vapor canister.

ADDITIONAL RECOMMENDATIONS:
Where contact with liquid is likely, such as in a spill or leak, impervious boots and clothing should be worn. High dose-
level warning signs are recommended for areas of principle exposure. Provide eyewash stations and quick-drench
shower facilities at convenient locations. For tank cleaning operations, see OSHA regulations, 29 CFR 1910.132 and 29
CFR 1910.133.

EXPOSURE GUIDELINES

INGREDIENT NAME ACGIH TLV OSHA PEL OTHER LIMIT

Pentafluoroethane None None **1000 ppm TWA
(8hr)
1,1,1-Trifluoroethane None None *1000 ppm TWA
(8hr)

* = Limit established by Honeywell.

** = Workplace Environmental Exposure Level (AIHA).
*** = Biological Exposure Index (ACGIH).

OTHER EXPOSURE LIMITS FOR POTENTIAL DECOMPOSITION PRODUCTS:

Hydrogen Fluoride: ACGIH TLV: 3 ppm ceiling

9. PHYSICAL AND CHEMICAL PROPERTIES

APPEARANCE: Clear, colorless liquid and vapor

PHYSICAL STATE: Gas at ambient temperatures
MOLECULAR WEIGHT: 98.8
CHEMICAL FORMULA: CHF2CF3 and CH3CF3
ODOR: Faint ethereal odor
SPECIFIC GRAVITY (water = 1.0): 1.07 @ 21.1°C (70°F)
SOLUBILITY IN WATER (weight %): Unknown
pH: Neutral
BOILING POINT: -46.7°C (-52.0°F)
FREEZING POINT: Not Determined
VAPOR PRESSURE: 153.9 psia @ 70°F
366.8 psia @ 130°F
VAPOR DENSITY (air = 1.0): 3.43
EVAPORATION RATE: >1 COMPARED TO: CCl4 = 1
% VOLATILES: 100 at 68°F (20°C)
FLASH POINT: Not applicable
(Flash point method and additional flammability data are found in Section 5.)

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Current Issue Date: February, 2003
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Genetron AZ-50 (R-507)

10. STABILITY AND REACTIVITY

NORMALLY STABLE? (CONDITIONS TO AVOID):

The product is stable.
Do not mix with oxygen or air above atmospheric pressure. Any source of high temperature, such as lighted cigarettes,
flames, hot spots or welding may yield toxic and/or corrosive decomposition products.

INCOMPATIBILITIES:
(Under specific conditions: e.g. very high temperatures and/or appropriate pressures) – Freshly abraded aluminum surfaces
(may cause strong exothermic reaction). Chemically active metals: potassium, calcium, powdered aluminum, magnesium
and zinc.

HAZARDOUS DECOMPOSITION PRODUCTS:

Halogens, halogen acids and possibly carbonyl halides.

HAZARDOUS POLYMERIZATION:
Will not occur.

11. TOXICOLOGICAL INFORMATION

IMMEDIATE (ACUTE) EFFECTS:

Pentafluoroethane (R-125)
LC50 : 4 hr. (rat) - > 800,000 ppm
Cardiac Sensitization threshold (dog) 75,000 ppm.
Trifluoroethane (R-143a)
LC50 : 4 hr. (rat) - > 540,000 ppm
Cardiac Sensitization NOEL – >250,000 ppm

DELAYED (SUBCHRONIC AND CHRONIC) EFFECTS:

Pentafluoroethane (R-125)
Teratogenic NOEL (rat and rabbit) - 50,000 ppm
Trifluoroethane (R-143a)
Subchronic inhalation (rat) NOEL - ≥50,000 ppm
Chronic NOEL – 10,000 ppm
Teratogenic NOEL (rat) - 40,000 ppm
Subchronic inhalation (rat) NOEL - 40,000 ppm

OTHER DATA:
Pentafluoroethane (R-125) - Not active in four genetic studies
Trifluoroethane (R-143a) - Not active in two genetic tests.

12. ECOLOGICAL INFORMATION

Degradability (BOD): Genetron AZ-50 (R-507) is a gas at room temperature; therefore, it is unlikely to remain in water.
Octanol Water Partition Coefficient: Log Pow = 1.48 (R-125)

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Current Issue Date: February, 2003
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Genetron AZ-50 (R-507)

13. DISPOSAL CONSIDERATIONS

RCRA

Is the unused product a RCRA hazardous waste if discarded? Not a hazardous waste
If yes, the RCRA ID number is: Not applicable

OTHER DISPOSAL CONSIDERATIONS:

Disposal must comply with federal, state, and local disposal or discharge laws. Genetron AZ-50 (R-507) is subject to U.S.
Environmental Protection Agency Clean Air Act Regulations Section 608 in 40 CFR Part 82 regarding refrigerant recycling.

The information offered here is for the product as shipped. Use and/or alterations to the product such as mixing with other
materials may significantly change the characteristics of the material and alter the RCRA classification and the proper disposal
method.

14. TRANSPORT INFORMATION

US DOT HAZARD CLASS: US DOT PROPER SHIPPING NAME: Liquefied gas, n.o.s. (Pentafluoroethane, 1,1,1-
Trifluoroethane)
US DOT HAZARD CLASS: 2.2
US DOT PACKING GROUP: Not applicable

US DOT ID NUMBER: UN3163

For additional information on shipping regulations affecting this material, contact the information number found in Section 1.

15. REGULATORY INFORMATION

TOXIC SUBSTANCES CONTROL ACT (TSCA)

TSCA INVENTORY STATUS: Components listed on the TSCA inventory

OTHER TSCA ISSUES: None

SARA TITLE III/CERCLA

"Reportable Quantities" (RQs) and/or "Threshold Planning Quantities" (TPQs) exist for the following ingredients.

INGREDIENT NAME SARA/CERCLA RQ (lb.) SARA EHS TPQ (lb.)

No ingredients listed in this section

Spills or releases resulting in the loss of any ingredient at or above its RQ requires immediate notification to the
National Response Center [(800) 424-8802] and to your Local Emergency Planning Committee.

SECTION 311 HAZARD CLASS: IMMEDIATE

PRESSURE

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Current Issue Date: February, 2003
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Genetron AZ-50 (R-507)

SARA 313 TOXIC CHEMICALS:

The following ingredients are SARA 313 "Toxic Chemicals". CAS numbers and weight percents are found in Section 2.

INGREDIENT NAME COMMENT

No ingredients listed in this section

STATE RIGHT-TO-KNOW

In addition to the ingredients found in Section 2, the following are listed for state right-to-know purposes.

INGREDIENT NAME WEIGHT % COMMENT

No ingredients listed in this section

ADDITIONAL REGULATORY INFORMATION:

Genetron AZ-50 (R-507) is subject to U.S. Environmental Protection Agency Clean Air Act Regulations at 40 CFR Part 82.

WARNING: Contains pentafluoroethane (HFC-125) and trifluoroethane (HFC-143a), greenhouse gases which may
contribute to global warming
Do Not vent to the atmosphere. To comply with provisions of the U.S. Clean Air Act, any residual must be recovered.

WHMIS CLASSIFICATION (CANADA):

This product has been evaluated in accordance with the hazard criteria of the CPR and the MSDS contains all the information
required by the CPR.

FOREIGN INVENTORY STATUS:

EU – EINECS #: HFC-125 2065578
HFC-143a 2069965

16. OTHER INFORMATION

CURRENT ISSUE DATE: February, 2003

PREVIOUS ISSUE DATE: January, 2000

CHANGES TO MSDS FROM PREVIOUS ISSUE DATE ARE DUE TO THE FOLLOWING:
Section 1: Updated contact information

OTHER INFORMATION: HMIS Classification: Health – 1, Flammability – 1, Reactivity – 0

NFPA Classification: Health – 2, Flammability – 1, Reactivity – 0
ANSI/ASHRAE 34 Safety Group – A1

Regulatory Standards:
1. OSHA regulations for compressed gases: 29 CFR 1910.101
2. DOT classification per 49 CFR 172.101

Toxicity information per PAFT Testing

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Current Issue Date: February, 2003