MSDS

CYCLOHEXANONE

1. Product Identification
Synonyms: Pimelic ketone; Cyclohexyl ketone; Ketohexamethylene
CAS No.: 108-94-1
Molecular Weight: 98.14
Chemical Formula: C6H10O

2. Composition/Information on Ingredients

Ingredient CAS No Percent

Hazardous
--------------------------------------- ------------

Cyclohexanone 108-94-1 98 - 100%

Yes

3. Hazards Identification
Emergency Overview
--------------------------
WARNING! FLAMMABLE LIQUID AND VAPOR. HARMFUL IF SWALLOWED, INHALED OR
ABSORBED THROUGH SKIN. AFFECTS CENTRAL NERVOUS SYSTEM, LIVER AND KIDNEYS.
CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT.

(tm)
SAF-T-DATA Ratings (Provided here for your convenience)
---------------------------------------------------------------------
Health Rating: 2 - Moderate (Life)
Flammability Rating: 2 - Moderate
Reactivity Rating: 1 - Slight
Contact Rating: 3 - Severe (Life)
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER
GLOVES; CLASS B EXTINGUISHER
Storage Color Code: Red (Flammable)
---------------------------------------------------------------------

Potential Health Effects

----------------------------------

Inhalation:
Causes irritation to the respiratory tract. Symptoms may include coughing,
shortness of breath. High concentrations have a narcotic effect.
Irritation effects normally prevent exposures high enough to cause
systemic effects.
Ingestion:
May produce abdominal pain, nausea. Aspiration into lungs can produce
severe lung damage and is a medical emergency. Other symptoms expected
to parallel inhalation.
Skin Contact:
Causes irritation to skin. Symptoms include redness, itching, and pain.
May be absorbed through the skin with possible systemic effects.
Eye Contact:
Vapors may cause irritation. Contact may cause corneal injury.
Chronic Exposure:
Prolonged or repeated exposure may cause skin rash or dermatitis. Damage
to the liver and kidneys may occur.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin, eye or central nervous system disorders,
or impaired liver, kidney, or pulmonary function may be more susceptible
to the effects of this substance.

4. First Aid Measures

Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Call a physician.
Ingestion:
Give large amounts of water to drink. Never give anything by mouth to an
unconscious person. Get medical attention.
Skin Contact:
In case of contact, immediately flush skin with plenty of water for at
least 15 minutes while removing contaminated clothing and shoes. Wash
clothing before reuse. Call a physician.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes,
lifting lower and upper eyelids occasionally. Get medical attention
immediately.

Note to Physician:
In small ingestions the major concern is aspiration and gastrointestinal
decontamination is not recommended. With larger ingestions there is
potential for systemic toxicity from gastrointestinal absorption and
decontamination is suggested, keeping in mind that aspiration is still
a concern.

5. Fire Fighting Measures

Fire:
Flash point: 43.9C (111F)
Autoignition temperature: 420C (788F)
Flammable limits in air % by volume:
lel: 1.1; uel: 9.4
Flammable. ( lel @ 100C )
Explosion:
Above flash point, vapor-air mixtures are explosive within flammable
limits noted above. Vapors can flow along surfaces to distant ignition
source and flash back. Contact with strong oxidizers may cause fire.
Sealed containers may rupture when heated. Sensitive to static discharge.
Fire Extinguishing Media:
Dry chemical, foam or carbon dioxide. Water spray may be used to keep fire
exposed containers cool, dilute spills to nonflammable mixtures, protect
personnel attempting to stop leak and disperse vapors.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved
self-contained breathing apparatus with full facepiece operated in the
pressure demand or other positive pressure mode.

6. Accidental Release Measures

Ventilate area of leak or spill. Remove all sources of ignition. Wear
appropriate personal protective equipment as specified in Section 8.
Isolate hazard area. Keep unnecessary and unprotected personnel from
entering. Contain and recover liquid when possible. Use non-sparking
tools and equipment. Collect liquid in an appropriate container or absorb
with an inert material (e. g., vermiculite, dry sand, earth), and place
in a chemical waste container. Do not use combustible materials, such as
saw dust. Do not flush to sewer! If a leak or spill has not ignited, use
water spray to disperse the vapors, to protect personnel attempting to
stop leak, and to flush spills away from exposures.

7. Handling and Storage

Protect against physical damage. Store in a cool, dry well-ventilated
location, away from any area where the fire hazard may be acute. Outside
or detached storage is preferred. Separate from incompatibles. Containers
should be bonded and grounded for transfers to avoid static sparks.
Storage and use areas should be No Smoking areas. Use non-sparking type
tools and equipment, including explosion proof ventilation. Containers
of this material may be hazardous when empty since they retain product
residues (vapors, liquid); observe all warnings and precautions listed
for the product.

8. Exposure Controls/Personal Protection

Airborne Exposure Limits:
-OSHA Permissible Exposure Limit (PEL): 50 ppm

-ACGIH Threshold Limit Value (TLV): 20 ppm (TWA) 50 ppm (STEL), skin, A3
- Confirmed animal carcinogen with unknown relevance to humans
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee
exposures below the Airborne Exposure Limits. Local exhaust ventilation
is generally preferred because it can control the emissions of the
contaminant at its source, preventing dispersion of it into the general
work area. Please refer to the ACGIH document, Industrial Ventilation,
A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded and engineering controls are not
feasible, a half-face organic vapor respirator may be worn for up to ten
times the exposure limit, or the maximum use concentration specified by
the appropriate regulatory agency or respirator supplier, whichever is
lowest. A full-face piece organic vapor respirator may be worn up to 50
times the exposure limit, or the maximum use concentration specified by
the appropriate regulatory agency or respirator supplier, whichever is
lowest. For emergencies or instances where the exposure levels are not
known, use a full-face piece positive-pressure, air-supplied respirator.
WARNING: Air-purifying respirators do not protect workers in
oxygen-deficient atmospheres.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat,
apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is
possible. Maintain eye wash fountain and quick-drench facilities in work
area.

9. Physical and Chemical Properties

Appearance:
Clear, colorless to slightly yellow, oily liquid.
Odor:
Odor is like acetone and peppermint.
Solubility:
15% in water @ 10C (50F).
Specific Gravity:
0.94 @ 25C/4C
pH:
No information found.
% Volatiles by volume @ 21C (70F):
100
Boiling Point:
155C (311F)
Melting Point:
-31C (-24F)
Vapor Density (Air=1):
3.4
Vapor Pressure (mm Hg):
5 @ 26C (79F)
Evaporation Rate (BuAc=1):
0.29
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizing agents. May cause spontaneous ignition and violent
reaction. May attack plastics, resins, and rubber.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.

11. Toxicological Information

Oral rat LD50: 1800 mg/kg; Inhalation rat LC50: 8000ppm/4-hour; Skin
rabbit LD50: 1 mL/kg; Irritation: eye rabbit, Standard Draize: 20 mg,
severe; skin rabbit, Open Draize: 500 mg, mild. Investigated as a
tumorigen, mutagen and reproductive effector.
--------\Cancer
Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC
Category
------------------------------------ ----- -----------
-------------
Cyclohexanone (108-94-1) No No
3

12. Ecological Information

Environmental Fate:
When released into the soil, this material is expected to readily
biodegrade. When released into the soil, this material is expected to
quickly evaporate. When released into the soil, this material is expected
to leach into groundwater. When released into water, this material may
evaporate to a moderate extent. When released into water, this material
may biodegrade to a moderate extent. This material has an estimated
bioconcentration factor (BCF) of less than 100. This material is not
expected to significantly bioaccumulate. When released into the air, this
material is expected to be readily degraded by reaction with
photochemically produced hydroxyl radicals. When released into the air,
this material is expected to have a half-life between 1 and 10 days.
Environmental Toxicity:
The LC50/96-hour values for fish are over 100 mg/l.

13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be handled as
hazardous waste and sent to a RCRA approved incinerator or disposed in
a RCRA approved waste facility. Processing, use or contamination of this
product may change the waste management options. State and local disposal
regulations may differ from federal disposal regulations. Dispose of
container and unused contents in accordance with federal, state and local
requirements.

14. Transport Information

Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: CYCLOHEXANONE
Hazard Class: 3
UN/NA: UN1915
Packing Group: III
Information reported for product/size: 4L

International (Water, I.M.O.)

-----------------------------
Proper Shipping Name: CYCLOHEXANONE
Hazard Class: 3
UN/NA: UN1915
Packing Group: III
Information reported for product/size: 4L

15. Regulatory Information

Xn,
R10 - Flammable
R20 - Harmful by inhalation
S2 - Keep out of the reach of children
S25 - Avoid contact with eyes

--------\Chemical Inventory Status - Part

1\---------------------------------
Ingredient TSCA EC Japan
Australia
----------------------------------------------- ---- --- -----
---------
Cyclohexanone (108-94-1) Yes Yes Yes
Yes

--------\Chemical Inventory Status - Part

2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL
Phil.
----------------------------------------------- ----- --- ----
-----
Cyclohexanone (108-94-1) Yes Yes No
Yes

--------\Federal, State & International Regulations - Part

1\----------------
-SARA 302- ------SARA
313------
Ingredient RQ TPQ List
Chemical Catg.
----------------------------------------- --- ----- ----
--------------
Cyclohexanone (108-94-1) No No No
No

--------\Federal, State & International Regulations - Part

2\----------------
-RCRA-
-TSCA-
Ingredient CERCLA 261.33
8(d)
----------------------------------------- ------ ------
Cyclohexanone (108-94-1) 5000 U057 No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: Yes Pressure: No
Reactivity: No (Pure / Liquid)

Poison Schedule: None allocated.

WHMIS:
This MSDS has been prepared according to the hazard criteria of the
Controlled Products Regulations (CPR) and the MSDS contains all of the
information required by the CPR.

16. Other Information

NFPA Ratings: Health: 1 Flammability: 2 Reactivity: 0
Label Hazard Warning:
WARNING! FLAMMABLE LIQUID AND VAPOR. HARMFUL IF SWALLOWED, INHALED OR
ABSORBED THROUGH SKIN. AFFECTS CENTRAL NERVOUS SYSTEM, LIVER AND KIDNEYS.
CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT.
Label Precautions:
Avoid contact with eyes, skin and clothing.
Avoid breathing vapor or mist.
Keep container closed.
Keep away from heat, sparks and flame.
Wash thoroughly after handling.
Use only with adequate ventilation.
Label First Aid:
If swallowed, give large amounts of water to drink. Never give anything
by mouth to an unconscious person. If inhaled, remove to fresh air. If
not breathing, give artificial respiration. If breathing is difficult,
give oxygen. In case of contact, immediately flush eyes or skin with plenty
of water for at least 15 minutes while removing contaminated clothing and
shoes. Wash clothing before reuse. In all cases call a physician.
Product Use:
Laboratory Reagent.
Revision Information:
MSDS Section(s) changed since last revision of document include: 15.

Shandong Haili Chemical Industry Co., Ltd

Address: Maqiao Town, Huantai County, Zibo, Shandong Tel: 0533-8539366
0533-8534456 Fax: 0533-8538361