Brand Name: Berirab Contents: Indication / Action:: Rabies
Brand Name: Berirab Contents: Indication / Action:: Rabies
Brand Name: Berirab Contents: Indication / Action:: Rabies
Indication / Action: Rabies prophylaxis after suspected exposure for persons who have no or incomplete vaccine
protection; following all injuries caused by animals, wild or domestic, known or suspected to be rabid, as well as after
contact of the mucous membranes or of the skin, esp of the injured skin w/ saliva of such animals.
Click to view Berirab P detailed prescribing infomation
Contraindications:
Adverse Reaction: Transient tenderness at inj site, cutaneous reactions & elevations in temp. Rarely, nausea,
vomiting & circulatory reactions (tachycardia, bradycardia, hypotension, sweating, vertigo) or anaphylactoid reactions.
In isolated symptoms, shock, particularly if inadvertently injected intravascularly.
Nursing Consideration: Not for multiple administration. Do not inject via intravascular route to prevent shock-like
symptoms. Administer in divided fractions in required comparatively large total doses. Administer in combination w/
rabies vaccine but on different site on the body.
Indication / Action: Pre-Exposure Immunization: Verorab is particularly recommended for: Professional groups
exposed to frequent contamination: Veterinary surgeons including students at veterinary colleges, technical
personnel working with veterinary surgeons, laboratory personnel handling material contaminated with rabies virus,
personnel in abattoirs and knacker's yard, taxidermists, gamekeepers, forestry workers and naturalists in enzootic
areas. Infants particularly exposed to the risk of rabies.
Post-Exposure Immunization: Treatment of subjects bitten by rabid animals or those suspected of being so.
Treatment of contact subjects.
Dosage: Pre-exposure 3 inj D0, D7 & D28, booster 1 yr later, & then 5 yrly (WHO experts). Post-exposure In
subjects unvaccinated against rabies: IM-schedule 5 x 0.5 mL on days D0, D3, D7, D14 & D30. ID-schedule2 x 0.1
mL at different sites on days D0, D3, D7 & 1 x 0.1 mL at a single site on days D30, D90.
Contraindications: Post-Exposure Immunization: All contraindications are secondary in cases of suspected rabid
contamination.
Pre-Exposure and Booster Immunization: In case of pregnancy or acute febrile illness, the vaccination should be
differed.
Side Effects: Local minor reactions eg, redness and slight induration at the injection site. Rare febrile reactions.
Nursing Consideration: Cases of true allergy to streptomycin &/or neomycin. Do not use the intradermal route in
patients receiving long-term corticosteroid or other immunosuppressive therapy or chloroquine, immunocompromised
patients, patients w/ severe wounds esp to head & neck.
Brand Name: Tetanus toxoid
Contents:
Dosage:
It is a contraindication to use this vaccine after anaphylaxis or other serious allergic reaction following a
previous dose of this vaccine, any other tetanus toxoid-containing vaccine, or any component of this
vaccine. Because of uncertainty as to which component of the vaccine may be responsible, no further
vaccination with a tetanus component should be carried out. Alternatively, such individuals may be referred
to an allergist for evaluation if further immunizations are to be considered.
convulsions (seizures)
fever over 103 °F (39.4 °C)
headache (severe or continuing)
sleepiness (excessive)
swelling, blistering, or pain at place of injection (severe or continuing)
swelling of glands in armpit
unusual irritability
vomiting (severe or continuing)
Redness or hard lump at place of injection
Less common
Adverse Reaction:
Nursin
Contents: Tetanus Ig G
Dosage: IM Patients w/ insufficient or unknown immunological status 250 iu. In case of infected wounds or
presence of foreign bodies in the wound, adult >90 kg of severe or continued blood or plasma loss, >24 hr
since the injury 500 iu. Patients not immunized or partially immunized Clean w/ minor wound Begin or
complete immunization as per schedule at standard dose. Clean w/ major &/or tetanus prone250 iu contralaterally
at standard dose & complete immunization as per schedule. Tetanus prone, delayed or incomplete
debridement 500 iu contralaterally at standard dose & complete immunization as per schedule plus antibiotic
therapy. Patients completely immunized since last booster dose 5-10 yr Clean w/ minor wound None. Clean w/
major &/or tetanus prone Standard dose. Tetanus prone, delayed or incomplete debridement Standard dose
plus antibiotic therapy. >10 yr Clean w/ minor wound Standard dose. Clean w/ major &/or tetanus prone 250 iu
contralaterally at standard dose. Tetanus prone, delayed or incomplete debridement 500 iu contralaterally at
standard dose plus antibiotic therapy.
Adverse Reaction: Chills, headache, fever, nausea, vomiting, allergic reactions, dizziness, low BP, arthralgia &
moderate low back pain.
Nursing Consideration: Closely monitor & carefully observe patients for any adverse events for at least 20 min
after administration. Suspicion of allergic or anaphylactic shock requires immediate discontinuation of of the inj.
Pregnancy & lactation.
Brand Name:
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Indication / Action:
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