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Drug Study Room 301 Telarma

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Alfred V.

Telarma

Name of Classification Dose Mechanism of Action Indications Contra Indications Adverse Effects Nursing Responsibility
Drug
Magnesium Antidysrhythmics 2 grams To trigger cerebral - Constipation - Hypersensitivity - Flushing - Observe constantly when
Sulfate IV Drip vasodilation, thus - Hypomagnesemia - Myocardial damage, - sweating given IV. Check BP and
q12 reducing ischemia - Prevention of diabetic coma, heart - sharply lowered pulse q10–15 min or more
generated by cerebral seizures in block blood pressure often if indicated.
vasospasm during an eclampsia/preecla - Hypermagnesemia - hypothermia - Lab tests: Monitor plasma
eclamptic event. The mpsia - Hypercalcemia - stupor magnesium levels in
substance also acts - Cardiac - respiratory patients receiving drug
competitively in blocking arrhythmias depression parenterally (normal: 1.8–
the entry of calcium into secondary to 3.0 mEq/L).
synaptic endings, thereby hypomagnesemia - Monitor respiratory rate
altering neuromuscular - Soaking minor closely. Report
transmission. cuts or bruises immediately if rate falls
below 12.
- Test patellar reflex before
each repeated parenteral
dose.
- Check urinary output,
especially in patients with
impaired kidney function.
- Observe patients
receiving drug for
hypomagnesemia for
improvement in signs of
deficiency.
- Have calcium gluconate
readily available in case of
magnesium sulfate toxicity.
Name of Classification Dose Mechanism of Action Indications Contra Adverse Effects Nursing Responsibility
Drug Indications
Cefuroxime Antiinfective; 750 mg Cefuroxime is a Susceptible mild to Hypersensitivity Body as a Whole: - Determine history of
antibiotic; IVTT bactericidal agent that moderate infections to Thrombophlebitis (IV hypersensitivity reactions to
second- ANST acts by inhibition of including cephalosporins site); pain, burning, cephalosporins, penicillins, and
generation bacterial cell wall pharyngitis/tonsillitis and related cellulitis (IM site); history of allergies, particularly
cephalosporin synthesis. Cefuroxime , acute maxillary antibiotics; superinfections, to drugs, before therapy is
has activity in the sinusitis, chronic positive Coombs' initiated.
presence of some bronchitis, acute test. - Lab tests: Perform culture and
beta-lactamases, both otitis media, sensitivity tests before initiation
penicillinases and uncomplicated skin GI: Diarrhea, nausea, of therapy and periodically
cephalosporinases, of and skin structure, antibiotic-associated during therapy if indicated.
Gram-negative and UTIs, gonorrhea, colitis. Skin: Rash, Therapy may be instituted
Gram-positive early Lyme disease pruritus, urticaria. pending test results. Monitor
bacteria. periodically BUN and creatinine
Urogenital: Increased clearance.
serum creatinine and - Inspect IM and IV injection
BUN, decreased sites frequently for signs of
creatinine clearance. phlebitis.
- Report onset of loose stools or
diarrhea.
- Monitor for manifestations of
hypersensitivity. Discontinue
drug and report their
appearance promptly.
- Monitor I&O rates and pattern:
Especially important in severely
ill patients receiving high doses.
Report any significant changes.
Name of Classification Dose Mechanism of Action Indications Contra Indications Adverse Effects Nursing Responsibility
Drug
Montelukast Bronchodilator 100 mg Blocks binding of Approved for Hypersensitivity to Body as a Whole: Asthenia, - Monitor effectiveness
(respiratory at HS leukotriene D4 to its treating chronic montelukast; fever, trauma. carefully when used in
smooth muscle receptor; alters asthma and severe asthma combination with
relaxant); pathophysiology prophylaxis and the attacks; CNS: Dizziness, headache. phenobarbital or other
leukotriene associated with prevention of bronchoconstrictio potent cytochrome
receptor inflammatory exercise-induced n due to asthma or GI: Abdominal pain, P450 enzyme inducers.
antagonist process that bronchoconstriction. NSAIDs; status dyspepsia, gastroenteritis,
contributes to signs It is also approved for asthmaticus; dental pain, abnormal liver - Lab test: Periodic liver
and symptoms of the relief of lactation. function tests (ALT, AST), function tests.
asthma symptoms of both diarrhea, nausea.
seasonal and
perennial allergic Respiratory: Nasal
rhinitis. congestion, cough,
influenza, laryngitis,
pharyngitis, sinusitis.

Skin: Rash.

Urogenital: Pyuria.
Name of Classification Dose Mechanism of Action Indications Contra Indications Adverse Effects Nursing Responsibility
Drug
Salbutamol bronchodilators 1 neb Salbutamol is a selective Indicated for the Hypersensitivity to the Tremor, - Check and verify with
nebulizations q4 β2-agonist providing symptomatic relief active substance headache, doctor’s order and Kardex.
short-acting (4-6 hour) and prevention of salbutamol (Sodium Tachycardia - Observe rights in
bronchodilation with a bronchospasm due chloride, Water for medication administration
fast onset (within 5 to bronchial injections, Sulfuric acid such as giving the right
minutes) in reversible asthma, chronic for pH adjustment) drug to the right patient
airways obstruction. At bronchitis, using the right route and at
therapeutic doses it acts reversible the right time.
on the β2-adrenoceptors obstructive airway - Monitor ECG, serum
of bronchial muscle. disease, and other electrolytes and thyroid
chronic function test results.
bronchopulmonary - Administer accurately
disorders in which because adverse reactions
bronchospasm is a and tolerance might occur.
complicating factor,
the acute
prophylaxis against
exercise-induced
bronchospasm and
other stimuli
known to induce
bronchospasm.

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