ANAPHY
ANAPHY
ANAPHY
1.Systemic Anatomy – study of structures of specific 1. Autoregulation – cells lack oxygen ,chemicals
body systems would be released to dilate blood vessels
e.g. nervous and circulatory systems. 2. Extrinsic regulation - during exercise nervous
system commands inc of heart rate so blood will circulate
2. Regional Anatomy – study of structures by body faster
regions.
1. Cytology – chemical and microscopic study of cells 3. Movement – motion occurring inside the human
body, either the whole body or individual cells or
2. Histology – study of normal tissues of the body even the organelles within these cells.
C. Embryology 4. Growth – an increase in body size that results from
-study of development of the human body from an increase in the size or number of cells.
• Muscle - movement
• Hemopoietic
1. Head
2. Neck
3. Trunk
a) Thorax
b) Abdomen
c) Pelvic cavity
d) Perineum
4. Upper extremities
5. Lower extremities
Ventral- thoracic, abdominopelvic
ANATOMICAL PLANES
4. Median plane
-saggital plane through the midline of the body
-from front to the back dividing it into right and left
halves
THE ANATOMICAL TERMS OF RELATIONSHIP
9. Superficial / External
SECTIONS OF THE BODY
10. Deep / Internal
Longitudinal section - vertical
11. Central
Section
12. Peripheral
Transverse sections -cross
13. Parietal
section
14. Visceral
Oblique sections: Cut the body not along any body
planes (slant)
TYPES OF CELL
PROKARYOTES EUKARYOTES
ORGANISM Bacteria protest,fungi,plants
Animals
ORGANELLES few /none nucleus,
mitochondria,
endoplasmic
reticulum, etc
DNA Circular / in the Linear / circular
cytoplasm Bounded by a
membrane
RNA and RNA and protein RNA synthesized in
PROTEIN synthesize in the the nucleus / protein
same in the cytoplasm
compartment
CELL DIVISION Binary fission Mitosis / meiosis
-Basic composition
Protoplasm/cytoplasm
cell membrane
TERMS OF MOVEMENT nucleus
Cytoskeleton- support
3. NUCLEUS Movement of solute from an area of high solute
- with DNA in the form of: concentration to an area of low solute concentration
with a CARRIER
a. heterochromatin (inactive)
b. euchromatin (active) OSMOSIS
FILTRATION
ACTIVE TRANSPORT
ISOTONIC- EQUAL
HYPERTONIC- SHRINKING
Osmosis
protein channels
active transport
fluid mosaic model
SIMPLE DIFFUSION
- Mostly water with chemical compounds in solution or Solution: atoms or ions distributed in medium
Polar compounds go into solution 3. ENDOPLASMIC RETICULUM
Nonpolar compounds go into colloidal System of membranes that makes up channels
suspension
Connects with outer nuclear and cell membranes
With organelles, inclusions, Cytoskeleton
ORGANELLES
TYPES OF ER:
Membrane bound organells - MEGLP M
– Mitochondria
Rough / Granular ER- for protein synthesis
E – Endoplasmic reticulum attached ribosomeS
(protein-EXTRACELLULAR USE)
G- Golgi Complex Smooth / Non-granular ER- fat transport and sex
hormone synthesis,HCL synthesis, release and
L- Lysosomes
recapture Ca+ in skeletal muslces.
P- Peroxisomes / micorbodies
4. GOLGI COMPLEX/
APPARATUS (Dictyosomes)
Newly Discovered / Temporary to your cells Collection of flat saclike cisternae
Concentration and collection of cellular
MELANOSOMES compounds
Storage warehouses of the cell
SECRETORY GRANULLES
Carbohydrate synthesis site
“packaging”
2. RIBOSOMES
Distributed throughout Cytoplasm
Attached to rough Endoplasmic Reticulum INCLUSIONS
No membrane covering
Site of protein synthesis 1. GLYCOGEN
free ribosomes- protein for INTRACELLULAR 2. LIPID
USE 3. PIGMENTS
a. Exogenous
b. Endogenous
1) lipofuscin
2) melanin
3) hemoglobin
4) bilirubin
4. CRYSTALS 35-45% of length of interphase
a.Crystals of Reinke b.Crystals 4. G2 phase
of Charcot-Bottcher phase before onset of mitosis
10-20% of length of interphase
CYTOSKELETON
MITOSIS
1. MICROFILAMENTS (7 nm in dia.)
2. INTEMEDIATE FILAMENTS (10 nm in dia.) Prophase
a. Keratin- epithelial cells Metaphase
b. Vimentin- mesenchymal cells Anaphase
c. Desmin- muscle cells Telophase
d. Glial fibrillary protein- glial cells of nervous
system
e. Neurofilaments- neurons
Centrioles
The Nucleus
INTERPHASE
18-24 hours
inactive / resting phase
1. . G1 (gap 1) phase
(-) DNA synthesis
(+) RNA and protein synthesis
30-50% of length of interphase KARYOTYPE
2. G0 phase
cells pull out of the cycle 23 PAIRS
3. S (synthesis) phase 22 pairs: autosomes
DNA synthesis/replication 1 pair: sex chromosome
XX : female Comparison of Mitosis and Meiosis
XY : male
MITOSIS layers of cells; not all apices of cells reach
Two daughter cells with exactly the same the surface (different heights of columnar
genetic material cells)
Cellular division for growth, maintenance and b.
repair 2. Stratified – more than one layer
a. Transitional (UROTHELIUM – found in
MEISOS urinary system) – several layer of cells
where the shape changes according to
Four daughter cells with half the genetic material functional status of the organ
Cellular division for Reproduction
SHAPES OF THE CELLS
1. SQUAMOUS
TISSUES
2. CUBOIDAL
3. COLUMNAR
CLASSIFICATION OF EPITHELIAL TISSUES
SPECIFIC SUBTYPES:
1. LINING/SURFACE EPITHELIUM - protection
ACCORDING TO NUMBER OF CELL LAYER +
2. GLANDULAR EPITHELIUM – Secretion
SHAPE OP THE CELL AND ITS SPECIAL
functions of epithelial tissues: FEATURE LIKE PRESENCE/ABSENCE OF CILIA
OR KERATIN
1. Protection 1. SIMPLE
A. Simple squamous
2. Secretion
Blood vessels- single layer of flat cell for easier
EPITHELIAL TISSUE diffusion of substances
Lungs(alveoli)- have only single layer of cells so
One of the fundamental types of tissue of the that oxygen and carbondioxide can easily pass through
body B. Simple cuboidal and C. Simple
Columnar
Secretion (secretory) or absorption
LINING / SURFACE EPITHELIUM
C. columnar
COMPOSITION:
1) non-ciliated
Epithelial Cells
2) ciliated
Extra Intercellular Substance
CHARACTERISTICS
2. STRATIFIED
Contiguous cells -closely packed together
A. Stratified Squamous
Basal lamina
If it needs to be moist in the mouth or vocal
Avascular
activity you have stratified squamous non -
Sheet or layers
keratinized
SUBTYPE OF LINING/SURFACE In the skin where it is dry there is a presence of
EPITHELIUM TISSUE keratin so you have stratified keratinized
B. Stratified cuboidal
Based on the number of : Sweat glands and sebaceous gland were you have
a secretory function
layers of cells:
C. Stratified Columnar
Lining cells of the ducts of salivary and mammary
gland
D. Pseudostratified Columnar
lining of the respiratory tract GLANDULAR
EPITHELIUM
1. UNICELLLULAR – 1 cell
ACCORDING TO MORPHOLOGY
1. TUBULAR- elongated
a. SIMPLE
1) simple tubular
b. COMPOUND
1) compound tubular Bone - compact, spongy
Elastic
Embryonic
Mesenchymal
Mucous
Mucus
- found only in MUSCLE TISSUE
the umbilical
cord. main characteristic is its ability to contract or
Wharton’s shorten
jelly.
TYPES OF MUSCLE TISSUE
SKELETAL
CARDIAC thermal damage and also bacteria
SMOOTH
6. Regulates heat loss from body surface
INTEGUMENTARY SYSTEM
composed of:
1. SKIN
2.SKIN APPENDAGES:
A.sweat gland
B. sebaceous gland
C. hairs
D. nails
SKIN
FUNCTIONS:
10. Contains cutaneous receptors that serve as • All but the deepest layers of epidermis are
sensors for touch, pressure, temperature composed of dead cells
and pain.
• Composed of 4-5 layers, depending on its
2 PRINCIPLE LAYER location within the body
1. STRATUM BASALE
Composed of single layer of cells in contact with the
dermis
4 types of cells:
A) keratinocytes
- produce keratin which toughens &
waterproofs skin
B) melanocytes
- synthesize the pigment melanin providing a protective
barrier to UV radiation in sunlight
2. STRATUM SPINOSUM
- cuboidal or slightly flattened cells
-Contains several layers of cells
-Spiny appearance due to changed shape of
EPIDERMIS keratinocytes
-With limited mitosis
• Superficial protective layer of the skin -This layer plus stratum basale are collectively
called Stratum Germinativum
3. STATUM GRANULOSUM - Brown-black pigment produced by the
- Consists of only 3-4 flattened rows of melanocytes of stratum basale
cells -Guards skin against damaging effect of UV rays of
- Cells here appear granular due to the presence of sunlight
keratohyaline granules -Gradual exposure to sunlight promotes increased
production of melanin; hence tanning of skin
4. STRATUM LUCIDUM (Clear Layer) -In albino, there is a normal number of melanocytes but
-Nuclei,organelles,and cell membranes are no longer lacks enzyme tyrosinase, that converts the amino acid
visible so this layer appears clear tyrosine to melanin
-Exists only in the lips and the thickened skin of soles -“freckles”- caused by aggregated patch of melanin
& palms -“vitiligo”- lack of melanocytes in localized areas of the
-Contains a transluscent substance called eleidin skin causing distinct white spots
COLORATION OF SKIN
- caused by expression of a combination of 3 pigments
(melanin, carotene, hemoglbin)
1. MELANIN
-Oxygenated blood flowing Shallow Flexion Lines - seen on knuckles and
through the dermis gives the skin surface of other joints
its pinkish tones Furrows in the forehead and face (wrinkles) - acquired
from continual contraction of facial muscles, such as from
SURFACE PATTERN
smiling or squinting in bright light or against the wind; facial
1. CONGENITAL PATTERNS lines become more strongly delineated as one ages
DERMIS - found all over the skin, except on palms and soles
- ducts usually empty into a hair follicle but some open directly
- Deeper and thicker than the epidermis onto skin surface
- secretion is called sebum, a mixture of oily substance and
- A strong and stretchy envelope that helps to hold the body
fragmented cells that keep skin soft and moist and prevents hair
together
from becoming brittle
- Blood vessels within the dermis nourish the living - if the drainage pathway for sebaceous glands becomes blocked for
portion of the epidermis some reason, the glands may become infected, resulting in acne
- sebum also contains chemicals that kill bacteria
- With numerous collagenous, elastic and reticular fibers that - become very active when sex hormones are produced in increased
give support to the skin amounts during adolescence, thus skin is oilier during this period of
life
- Highly vascular and glandular
LAYERS OF DERMIS
1. PAPILLARY LAYER
2.RETICULAR LAYER
CUTANEOUS GLANDS
2. SWEAT GLANDS secrete milk during lactation
- Under the stimulus of pituitary gland
- also called sudoriferous glands
- widely distributed in the skin; numerous in palms,
soles, axillary and pubic regions
- secretion evaporates and cools in the body 4. HAIR
4. NAILS
Consists of:
COMPONENTS;
1. BONE CELLS
OSTEOBLASTS – embryonic bone cells & active in
bone formation
OSTEOCYTES – mature osteoblasts
OSTEOCLASTS – bone reabsorption/resorption and
remodeling.
2. MATRIX
COLLAGENOUS FIBERS – give resilience to bones
CALCIFIED GROUND SUBSTANCES -give
hardness to bones, Calcium Phosphate, Calcium Carbonate
According to shapes
According to development
According to location
H- shape union of:FRONTAL, Suture
PAREITAL, SPHENOID, CORONAL
TEMPORAL SAGITTAL
LAMBOIDAL
*related to the middle meningeal artery common
cause of EPIDURAL HEMORRHAGE
CRANIAL BONES
CRANIAL BONES
CALVARIUM
Frontal
Parietal
Temporal
Sphenoid
occipital
FACIAL BONE
HYOID
Facial bones– 14
STERNUM
Parts;
- Manubrium
- Body
-Xiphoid Process
Landmarks:
OSSICLES
- three bones in either middle ear that are among the smallest
bones in the human body. They serve to transmit sounds from
the air to the fluid-filled labyrinth (cochlea).
Malleus (Hammer)
Incus(Anvil) Stapes
(stirrup)
RIBS
Vertebra
Cervical
typical
- C3-C6
-Quadrangular Body
-Transverse Foramen
-Bifid Spine
-Triangular vertebral foramen
Atypical
– C1(Atlas)(-)body & spine
-C2(Axis)(+)dens/odontoid process
-C7(Vertebra Prominens)bifid spine
Thoracic
-heart shaped body
-costal facets on body and transverse processes
-long pointe spine obliquely going down
typical-T3-T10
Radius (thumb)(lateral)
Carpals(wrist bone)/Metacarpals/Phalanges
D. Lower Extremities
Femur- Thigh bone – Longest bone
Tibia (medial leg bone) & Fibula (lateral leg bone)
Patella – kneecap (sesamoid bone)
Tarsals/Metatarsal/Phalanges
Synovial
-with a fibrous capsule around a synovial cavity between the
articulating bones.