MS Antigen

MATERIAL SAFETY DATA SHEET
SPAFAS MS Plate Antigen for Plate Agglutination Test
1. PRODUCT AND COMPANY INFORMATION
Product Name Mycoplasma Synoviae Antigen

Trade Name SPAFAS MS Plate Antigen for Plate Agglutination
Test
Other Identification NA
Manufacturer/Supplier Charles River Laboratories, Inc
Address 251 Ballardvale Street, Wilmington, MA 01887
Phone 781-222-6000
Emergency Phone Number INFOTRAC (800) 535-5053
MSDS First Issued February 23, 2006

MSDS Data Revised September 13, 2010
2. HAZARDS IDENTIFICATION
Routes of Entry Inhalation, skin contact, ingestion, eye contact

Health Effects – Eyes Direct contact with liquid may cause irritation,
redness, pain and conjunctivitis.
Health Effects – Skin Direct contact with liquid may cause irritation to
skin. Symptoms include redness, itching, and
pain.
Health Effects – Ingestion May produce abdominal pain, nausea.
Health Effects – Inhalation There is negligible risk of inhalation when used
and handled as directed by the product insert.
CARCINOGENIC EFFECTS: Not considered carcinogenic by NTP, IARC, and
OSHA
MUTAGENIC EFFECTS: Not available
TERATOGENIC EFFECTS: Not available
DEVELOPMENTAL TOXICITY: Not available
3. COMPOSITION AND INFORMATION ON INGREDIENTS

Component Name CAS # Concentration (%)
Mycoplasma synoviae, WVU1853 NA <5
Crystal Violet, biological stain 548-62-9 <1
Potassium phosphate, monobasic 7778-77-0 <2
Sodium phosphate, dibasic 7558-79-4 <2
Sodium chloride 7647-14-5 <2
Bovine serum albumen, Fraction V NA < 10
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Tween 80 9005-64-5 <2
Neomycin sulfate 1405-10-3 <1
Deionized water 7732-18-5 Balance
4. FIRST AID MEASURES
Fist Aid – Eyes Immediately flush eyes with large quantities of

water for at least 15 minutes. Contact a
physician.
First Aid – Skin Remove contaminated clothing and wash affected

areas with soap and water. Contact a physician if
irritation persists. Launder clothing prior to
reuse.
First Aid – Ingestion Do not induce vomiting unless directed by a

medical professional. Never give anything by
mouth to an unconscious or convulsing person. If
conscious, have victim rinse mouth with water,
but do not swallow. Contact a physician
immediately.
5. FIRE FIGHTING MEASURES
Extinguishing Media Water, Water Mist, Dry Chemical, CO2, or Foam.
Unusual Fire and

Explosive Hazards None
Special Fire Fighting Procedures For large fires, fire fighters should be equipped
with self-contained breathing apparatus.
6. ACCIDENTAL RELEASE MEASURES
Absorb spilled material using appropriate absorbent material such as spill pads,
speedi-dry, or paper towels. Dispose of spill clean-up debris as Biohazardous Waste.
Page 2 of 5
7. HANDLING AND STORAGE
Protect against physical damage. Store in a cool, dry well-ventilated location.

Separate from incompatible. For disposal, see Section 13.
8. EXPOSURE CONTROL AND PERSONAL PROTECTION
OSHA Threshold Limit Value: NA

ACGIH Threshold Limit Value: NA
Engineering Control Measures Not required if product is used as directed by

product insert. Follow typical laboratory safety
practices.
Respiratory Protection Not required if product is used as directed by

product insert.
Hand Protection Use impervious nitrile gloves where prolonged or

repeated contact with skin may occur.
Eye Protection Safety glasses
Body Protection No special protective clothing is necessary when

used as directed by product insert.
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance Blue
Odor Minimal
Odor Threshold Not available
Physical State Liquid
pH 6.8 – 7.2
Melting Point Not available
Freezing Point Not available
Boiling Point 100 to 110
Flash Point ›200
Evaporation Rate Not available
Flammability Not available
Upper Explosive Limit Not available
Lower Explosive Limit Not available
Vapor Pressure Not determined, assumed similar to water.
Specific Gravity 1.0 to 1.1
Solubility in Water Miscible
Auto-Ignition Temperature Not available
Decomposition Temperature Not available
Vapor Density (Air=1) Not determined, assumed similar to water.
Page 3 of 5
10. STABILITY AND REACTIVITY
Chemical Stability Material is stable

Conditions to Avoid Material is Stable
Incompatible Materials Strong oxidizers
Hazardous Polymerization Hazardous polymerization will not occur
Hazardous Decomposition Products C0, C02
Possibility of Hazardous Reactions NA
11. TOXICOLOGICAL INFORMATION
Toxicity not tested as a mixture, toxicity data for relevant ingredients provided
below.
Crystal Violet ORL-RAT LD 50:420 MG/KG
12. ECOLOGICAL INFORMATION
Environmental Fate If released to the environment, material is

expected to biodegrade rapidly.
Environmental Toxicity When used as directed by the product insert, this

material is expected to post a negligible risk to
the environment.
13. DISPOSAL CONSIDERATIONS
Dispose of in accordance with all applicable local, state and national regulations.
Labels should not be removed from containers until they have been cleaned. Rinse
empty containers with water and dispose with ordinary trash.
14. TRANSPORTATION INFORMATION
DOT CFR 172.101 Data Not regulated by DOT
15. REGULATORY INFORMATION
TSCA Listing All components have been verified for inclusion

on the EPA Toxic Substances Control Act
Chemical Substance Inventory
State No significant risk level: None of the chemicals in

this product are listed.
SARA Title III Section 311/312 Crystal Violet: Categorized as an Immediate

(Acute) Health Hazard
Page 4 of 5
Citric Acid: Categorized as an Immediate (Acute)

Health Hazard
Clean Air Act – Ozone This product does not contain a Class I or II
ozone depleting substance (ODS) as defined by
the US Clean Air Act Section 602 at 40 CFR 82.
VOC Content This product does not contain VOC’s.
16. OTHER INFORMATION
Disclaimer: The data contained herein is based on information that Charles River
Laboratories believes to be reliable, but no expressed or implied
warranty is made with regard to the accuracy of such data or its
suitability for a given situation. Such data relates only to the specific
product described and not to such products in combination with any
other product and no agent of Charles River Laboratories is authorized
to vary any such data. Charles River Laboratories and its agents
disclaim all liability for any action taken or foregone on reliance upon
such data.
Page 5 of 5

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MATERIAL SAFETY DATA SHEET

SPAFAS MS Plate Antigen for Plate Agglutination Test

1. PRODUCT AND COMPANY INFORMATION

Product Name Mycoplasma Synoviae Antigen

MSDS First Issued February 23, 2006

Routes of Entry Inhalation, skin contact, ingestion, eye contact

3. COMPOSITION AND INFORMATION ON INGREDIENTS

Mycoplasma synoviae, WVU1853 NA <5

Crystal Violet, biological stain 548-62-9 <1

Potassium phosphate, monobasic 7778-77-0 <2

Sodium phosphate, dibasic 7558-79-4 <2

Sodium chloride 7647-14-5 <2

Bovine serum albumen, Fraction V NA < 10

Tween 80 9005-64-5 <2

Neomycin sulfate 1405-10-3 <1

Deionized water 7732-18-5 Balance

4. FIRST AID MEASURES

Fist Aid – Eyes Immediately flush eyes with large quantities of

First Aid – Skin Remove contaminated clothing and wash affected

First Aid – Ingestion Do not induce vomiting unless directed by a

5. FIRE FIGHTING MEASURES

Extinguishing Media Water, Water Mist, Dry Chemical, CO2, or Foam.

Unusual Fire and

6. ACCIDENTAL RELEASE MEASURES

7. HANDLING AND STORAGE

Protect against physical damage. Store in a cool, dry well-ventilated location.

8. EXPOSURE CONTROL AND PERSONAL PROTECTION

OSHA Threshold Limit Value: NA

Engineering Control Measures Not required if product is used as directed by

Respiratory Protection Not required if product is used as directed by

Hand Protection Use impervious nitrile gloves where prolonged or

Eye Protection Safety glasses

Body Protection No special protective clothing is necessary when

9. PHYSICAL AND CHEMICAL PROPERTIES

10. STABILITY AND REACTIVITY

Chemical Stability Material is stable

11. TOXICOLOGICAL INFORMATION

Crystal Violet ORL-RAT LD 50:420 MG/KG

12. ECOLOGICAL INFORMATION

Environmental Fate If released to the environment, material is

Environmental Toxicity When used as directed by the product insert, this

13. DISPOSAL CONSIDERATIONS

14. TRANSPORTATION INFORMATION

DOT CFR 172.101 Data Not regulated by DOT

15. REGULATORY INFORMATION

TSCA Listing All components have been verified for inclusion

State No significant risk level: None of the chemicals in

SARA Title III Section 311/312 Crystal Violet: Categorized as an Immediate

Citric Acid: Categorized as an Immediate (Acute)

VOC Content This product does not contain VOC’s.

16. OTHER INFORMATION

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