DIRECTORATE OF NURSING AFFAIRS PSYCHIATRIC NURSING MANUAL

DRUGS USED IN PSYCHIATRIC UNIT

ANTI PSYCHOTIC-DRUGS

Generic Name Trade Name Dosage Range Indications Side Effects Caution
1. Chlorpromazine Largactil 150 - 300 mg daily Schizophrenia, Extra pyramidal Elderly, drivers, C. V.
Related psychoses symptoms like dystonic S. disease, Epilepsy,
Mania. reaction parkinsonism Renal and hepatic
Sever anxiety Hypotension. lessions, prostate
Psychotic depression Drowsiness, jaundice's, enlargement. Narrow
photo-sensitivity, rashes, angle glaucoma.
Excessive salivation
Protrusion of tunge. Wait
gain corneal opacities
retinal pigmentation ,
tardive duskiness.
2. Thiorodazine Melleril 150 to 300 mg daily Schizophrenia Side effects are similar to Similar to the
Related psychoses the chlorpromazine. chlorpromazine.
Psychotic depression Hypotension
Sever Anxiety Delayed ejaculation
Rational pigmentation
3. Trifluoperazine Stelazine 5 to 20 mg daily Schizophrenia and types. More extra pyramidal Similar to the
Sever anxiety symptoms chlorpromazine.
4. Fluphenazine Modecate 12.5 to 25 mg Schizophrenia and types. Side effects similar to the Similar to the
every 2 - 4 weeks Severe anxiety chlorpromazine chlorpromazine.
5. Haloperidol Serenace 5 mg to 100 mg Schizophrenia Similar to chlorpromazine Similar to the
Mania chlorpromazine.
Sever anxiety
Related psychosis

Generic Name Trade Name Dosage Range Indications Side Effects Caution

DRUGS USED IN PSYCHIATRY 5 - 2 -1

 DIRECTORATE OF NURSING AFFAIRS PSYCHIATRIC NURSING MANUAL

6. Flupenthixol Fluanoxl 3 - 12 mg daily Schizophrenia Less extra pyramidal Similar to the

Mania effect chlorpromazine.
Sever Anxiety
Related psychosis
7. Flupethixol Depixol 20 - 40 mg Schizophrenia Less extra pyramidal Similar to the
Decanoate Once in a month Mania effect chlorpromazine.
Sever Anxiety
Related psychosis
8. Pimozide Oral 4 - 10 mg Schizophrenia Less extra pyramidal Similar to the
Mania effect chlorpromazine.
Sever Anxiety
Related psychosis

ANTI- DEPRESSANTS

Generic Name Trade Name Dosage - Range Indications Side - Effects Caution
1. Imipramine Tofranil 75 - 150 mg Depression Dry mouth Drivers
Nocturnal Enuresis Constipation nausea Elderly
Phobic Neurosis Postural hypotension C. V. S. Disease
Obsessional rumination Sedation Glaucoma
Tremor Urinary retention
Blurring Epilepsy
Impaired ejaculation
2. Amitriptyline HCl Tryptizol 75 - 150 mg Depression More sedative Drivers
Nocturnal Enuresis More side effects Elderly
Phobic Neurosis C. V. S. Disease
Obsessional rumination Glaucoma
Urinary retention
Epilepsy

Generic Name Trade Name Dosage - Range Indications Side - Effects Caution

DRUGS USED IN PSYCHIATRY 5 - 2 -2

 DIRECTORATE OF NURSING AFFAIRS PSYCHIATRIC NURSING MANUAL

3. Trimipramine Surmontil 75 - 1560 mg Depression More sedative Drivers

Nocturnal Enuresis More side effects Elderly
Phobic Neurosis C. V. S. Disease
Obsessional rumination Glaucoma
Urinary retention
Epilepsy
4. Maprolitive Ludiomil 50 - 150 mg Depression More sedative Drivers
Nocturnal Enuresis More side effects Elderly
Phobic Neurosis C. V. S. Disease
Obsessional rumination Glaucoma
Urinary retention
Epilepsy

ANTI MANIC-DRUGS

Generic Name Trade Name Dosage - Range Indications Side - Effects Caution
1. Lithium Carbonate Camcolit 400 mg to 2000 mg Mania Nausea Contra indication in
Hypo mania Vomiting case of renal disease
Bi polar Diarrhea
Affective disorders Tremor
Drowsiness
Oedema
Wait gain
Myocloric jerks
Loss of memory
2. Carbamazepine Tegretol Mania Drowsiness
Temporal lobe Lesions
Alcohol withdrawal
Schizo affective
psychoses

DRUGS USED IN PSYCHIATRY 5 - 2 -3

 DIRECTORATE OF NURSING AFFAIRS PSYCHIATRIC NURSING MANUAL

ANTI- ANXIOLYTICS

Generic Name Trade Name Dosage Range Indications Side Effects Caution
1. Diazepam Valium 5 mg to 30 mg Anxiety Drowsiness Driving
Alcohol withdrawal Convulsion Elderly
Panic attacks Headache
Hysterical Neurosis
2. Lorazepam Ativan 3 to 10 mg = = =
3. Nitrazepam Mogadon 5 to 10 mg = = =
4. Chlordiazepoxide Librium 10 mg - 150 mg Alcoholism = =

ANTI-PARKINSONISM DRUGS

Generic Name Trade Name Dosage Range Indications Side Effects Caution
1. Trihexy phendiyl Artane 2 mg to 6 mg In case of side effect.
HCL Any anti psychotic drugs
2. Procychidine HCL Kemadrin 5 mg to 40 mg In case of side effect .
Any anti psychotic drugs

OTHER DRUGS USED IN PSYCHIATRY SETTING - 1

SN Pharmaceutical Group Trade Name Generic Dose Side Ffects

01 Typical neuroleptics. Major ١. Largactil 25, 50, & 100 mgs Chlorpronazine The doses vary according to
tranquilizers or sedatives the severity of condition and EPS
occurrence of side effects
2. Serenace 1.5, 5, and 10 mg Halaperidol
3. Stelazine 1,5 and 10 mg Trifluperazine 5 – 20 mg EPS
4. Melleril 10, 25 and 50 mg Thioridazine 150 – 600 mg EPS lower retinal toxicity
in high doses
5. Fluanzol 1 and 3 mg Flupenthixol 3 – 9 up-to 18 mg EPS more / less sedating
6. Phenergan Promethazine Only as sedative
7. Kemadrin 5 mg Procyclidine Antimuscarinic

DRUGS USED IN PSYCHIATRY 5 - 2 -4

 DIRECTORATE OF NURSING AFFAIRS PSYCHIATRIC NURSING MANUAL

SN Pharmaceutical Group Trade Name Generic Dose Side Ffects

02 Injections / Sedatives 1. Injection Serenace 5 mg Haloperidol 5 – 10 mg Q/D up-to 100 mg
or deporting once monthly
2. Injection Phenergan Promethazine 25 – 50 mg
3. Injection Dopixol Acuphase Clopenthixol 50 – 100 mg
03 Depot injections “Slow 1. Injection Modecate 25 mg/ml Fluphenazine 25 mg every 2 weeks or 4 Higher incidence of EPS
Release” weeks
2. Injection Depixol 40 mg in 2 Olanzepine 20 – 40 mg by deep 1 m Higher incidence of EPS
ml injection every 2 –4 weeks
04 For negative symptoms of a 1. Zyprexa 7,5 and 10 mg Olanzepine 7,5 – 10 mg Nausea
typical antischizophrenic
2. Risperidone 1, 2, 3 mg Risperidal 1 –6 mg Nausea
05 For alcohol withdrawal and for Hemirvin / Diazepam Chloromethiazole 9 – 12 caps tapering dose GI disturbances, nazal
status epileptics 300 mg or maximum for 9 days irritations, drwosiness,
equivalent i.e. base and dependence
Note: Hypnotics should be used only when insomnia is severe, disabling or subjecting the individual to extreme stress.

OTHER DRUGS USED IN PSYCHIATRY SETTING - 2

SN Pharmaceutical Group Trade Name Generic Dose Side Ffects

1 Anxiolytics – Minor 1. Lexotanil 1,5 & 3 mg tables Bromazepam 3 mg – 18 mg Drowsiness, sedation and
tranquilizers – sedative ataxia
2. Diazepam 5 and 2 mgs, Benzodiazepine 6 – 30 mg for anxiety Drowsiness, sedation and
Injection – 10 mg in 2 ml ataxia
2 New anti-anxiety non sedating 1. Buspar 5 and 10 mg Buspirone 5 – 10 up-to 45 mg
2. Inderal 10 and 40 mg Proprandol 5 –10 up-to 160 mg in panic
attacks with other
bBenzodiazepines
Note: Hypnotics should be used only when insomnia is severe, disabling or subjecting the individual to extreme stress.

DRUGS USED IN PSYCHIATRY 5 - 2 -5

 DIRECTORATE OF NURSING AFFAIRS PSYCHIATRIC NURSING MANUAL

ANTIDEPRESSANTS

SN Pharmaceutical Group Trade Name Generic Dose Side Ffects

01 Tricyclic anti-depressants 1. Tryptizol 25 and 25 mg Amitriptyline 25 – 50 mg max. 150 mg Anti-muscarinic e.g. dry
mouth, blurred vision,
constipation, and urine
retention
2. Anafranil 25 mg Clomepramine 10 25 mg max. 150 mg
3. Imiprex Tofranil 25 mg Imipramineoxide 25 – 75 300 Orthostatic hypotention,
Imupramine Hcl tachycardia occationally,
and inappropriate
secretion of ADH
02 Tetracyclic Anti-depressant 1. Ludiomil 25 and 50 mg Maprotylline Hcl 25 – 75 – 150 up-to 225 mg They have effects on all
body systems
2. Athymil Mianserine Hcl 30 – 4- - 90 up-to 200 mg
03 SSRI Selective senetonin 1. Seroxal 20 mg Paroxetine Hcl 20 – 50 mg Nausea, somnolence,
reuptak inhibitors insomina, and dry mouth
2. Prozac 20 mg Fluoxetine 20 – 80 mg GI disturbances,
insomina, drowsiness,
and anorexia
3. Cipram 20 mg Citalopram 20 – 60 mg
04 Antimanic for manic Camacolit 400 mg Lythium Carbonate 0,4 – 1,2 gm Nausea, vertigo, fine
depressive illness tremor, polyuria,
polydipsia, muscle
weakness and lethargy.
ECG changes oedema
05 Mild anxiolytic and anti- Atarax 10 mg Hydroxyzine Hcl 10 – 20 mg Diziness
depressant

Note: Hypnotics should be used only when insomnia is severe, disabling or subjecting the individual to extreme stress.

DRUGS USED IN PSYCHIATRY 5 - 2 -6