9.

Cell and Cell Division

1. Which of the following statements is correct with respect to cell cycle?
a) The DNA content of cell remains constant during entire cell cycle
b) A cell G1 phase has double the amount of DNA than a cell in G 2 phase
c) Each chromosome has two chromatic in G1 phase
d) Nerve cell in adult human are in G0 state
2. Given below is a schematic break-up of the phases /stages of cell cycle. Which one of the following is the correct
indication of the stage /phase in the cell cycle?

a) C – Karyokinesis b) D – Synthetic phase c) A – Cytokinesis d) B – Metaphase

3. During mitosis, ER and nucleolus begin to disappear at:
a) Late prophase b) Early metaphase c) Late metaphase d) Early prophase
4. Which stages of cell division do the following figures A and B represent respectively?

a) a) Meta phase – Telophase b) Telophase – Metaphase

c) Late anaphase – Prophase d) Prophase – Anaphase
5. At metaphase, chromosomes are attached to the spindle fibers by their:
a) Satellites b) Secondary constrictions c) Kinetochores d) Centromeres
6. A stage cell division is shown in the figure. Select the answer which gives the correct identification of the stage
with its characteristics.

a) Telophase Nuclear envelope reforms, Golgi complex

reforms,
b) Late anaphase Chromosomes move away from equatorial plate,
Golgi complex not present
c) Cytokinesis Cell plate formed mitochondria distributed
between two daughter cells
d) Telophase Endoplasmic reticulum and nucleolus not
reformed yet.
7. During which phase(s) of cell cycle, the amount of DNA in a cell remains at 4C level if the initial amount is denoted
at 2C?
a) G0 and G1 b) G1 and S c) Only G2 d) G2 and M
8. In ‘S’ phase of the cell cycle:
a) The amount of DNA doubles in each cell b) The amount of DNA remains same in each cell
c) Chromosome number of is increased d) The amount of DNA is reduced to half in each cell
9. A somatic cell that just completed the S phase of its cell cycle as compared to gamete of the same species has.
a) Twice the number of chromosomes and twice the amount of DNA
b) Same number of chromosomes but twice the amount of DNA
c) same number of chromosomes and four times the amount of DNA
d) Four times the number of chromosomes and twice the amount of DNA
10. _______ and ________ coined the term ‘Meiosis’.
a) Van Burin and Hertwig b) Boveri and Stuka
c) Walleye and Hofmeister d) Farmer and Moore
11. Which of the following is not a characteristic feature during mitosis in somatic cells?
a) Spindle fibres b) Disappearance c) Chromosome movement d) Synapsis
12. During cell growth, DNA synthesis takes place in:
a) G1 Phase b) G2 Phase c) M phase d) S phase
13. Which of the following options give the correct sequence of events during mitosis?
a) Condensation → Nuclear membrane dissembles→ Arrangement at equator → Centromere division →
Segregation →Telophase.
b) Condensation → Crossing over → Nuclear membrane disassembly → Segregation → Telophase.
c) Condensation → Arrangement at equator → Centromere division → Segregation → Telophase.
d) Condensation →Nuclear membrane disassembly → Crossing over → Segregation → Telophase.
14. Synapsis occurs between:
a) mRNA and ribosome’s b) Spindle fibres and centromere.
c) Two homologous chromosomes d) A male and a female gamete
15. Identify the meiotic stage in which the homologous chromosomes separate while the sister chromatids remain
associated at their centromeres.
a) Metaphase – II b) Anaphase – I c) Anaphase – II d) Metaphase – I
16. During gamete formation, the enzyme recombinase participates during:
a) Metaphase – I b) Anaphase – II c) Prophase – I d) Prophase – II
17. Given below is the representation of a certain event at a particular stage of a type of cell division. Which is this
stage?

a) Prophase – I during meiosis b) Prophase – II during meiosis

c) Prophase of mitosis d) Both prophase and metaphase of mitosis
18. The enzyme recombinase is required at which state of meiosis?
a) Pachytene b) Zygotene c) Diplotene d) Diakinesis
19. The process of cytokinesis refers to the division of:
a) Cytoplasm b) Chromosomes c) Nucleus d) Organelles
20. Arrange the following events of meiosis in correct sequence.
(A) Crossing over (B) Synapsis (C) Terminalization of chiasmata (D) Disappearance of nucleolus
a) (B) → (A)→ (C) → (D) b) (A) → (B)→ (C) → (D)
c) (B) → (C)→ (D) → (A) d) (B) → (A)→ (D) → (C
21. In meiosis, the crossing over is initiated at:
a) Pachytene b) Leptotene c) Zygotene d) Diplotene
22. Match the stage of meiosis in column – I to their characteristic features in Column – II and select the correct option
using the codes given below:

Column – I Column – II
A) Pachytene 1) Pairing of homologous chromosomes
B) Metaphase – I 2) Terminalization of chiasmata
C) Diakinesis 3) Crossing over takes place
D) Zygotene 4) Chromosomes align at equational plate
Codes:
a) A : 1, B : 4, C : 2, D : 3 b) A : 2, B : 4, C : 3, D : 1
c) A : 4, B : 3, C : 2, D : 1 d) A : 3, B : 4, C : 2, D : 1
23. At what phase of meiosis, homologous chromosomes are separated?
a) Anaphase – II b) Prophase – I c) Prophase – II d) Anaphase – I
24. All organisms start their life with:
a) Single cell b) Many cells c) Few cells d) Few organs
25. Cell growth (increase in cytoplasm) is a/an:
a) Continuous process b) Discontinuous process
c) Irregular process d) Retrogressive process
26. Human cell can divide itself once approximately in:
a) 24 hours b) 24 minutes c) 24 seconds d) 24 days
27. The duration of cell cycle in yeast is approximately:
a) 90 seconds b) 90 minutes c) 20 minutes d) 45 minutes
28. The M phase in human cells lasts for:
a) 1-hour b) 2 hours c) 23 hours d) 4 hours
29. Which of the following is correct about interphase?
a) It is the phase present between two successive M phases.
b) It lasts for more than 95% in the duration of cell cycle in human cell.
c) It is also known as resting phase.
d) All of the above.
30. The G1 phase is not characterized by:
a) Continuous growth b) Active metabolism
c) DNA replication d) Non-replication of DNA
31. S phase is not characterized by:
a) DNA duplication b) No increase in chromosome number
c) DNA replication d) Duplication of centriole in nucleus of eukaryotic animal cell
32. Which of the following is continuously occurring in dividing G 1, S and G2 phase?
a) DNA replication b) DNA duplication
c) Centriole duplication d) Growth of cells
33. If a cell has 2n number of chromosomes in G1 phase, then what is the number of chromosomes in cell after S
phase?
a) n b) 4n c) 2n d) 8n
34. Anaphase is characterized by:
a) Splitting of centromere b) separation of chromatids
c) Movement of chromatid to opposite poles d) All of the above
35. Mitosis helps:
a) Growth b) Repair c) Both (a) and (b) d) None of these
36. Plant shows continuous growth of plant throughout their life due to:
a) Mitosis b) Amitosis c) Meiosis d) All of these
37. Terminalization occurs during:
a) Mitosis b) Diakinesis c) Cytokinesis d) Meiosis-II
38. The number of chromosome groups at equatorial plate of metaphase – I of a plant having 2n = 50 chromosomes
shall be:
a) 100 b) 75 c)50 d) 25
39. In meiosis I, the centromere undergoes:
a) No division
b) Division between anaphase and inter phase
c) Division between prophase and metaphase
d) Division but the daughter chromosomes do not separate.
40. Meiosis II performs:
a) Synthesis of DNA and centromere b) Separation of sex chromosomes
c) Separation of chromatids d) Separation of homologous chromosomes
41. Significance of meiosis lies in:
a) Reduction of chromosome number to one half.
b) Maintaining constancy of chromosome number during sexual reproduction.
c) Production of genetic variability.
d) All of the above.
42. During meiosis, crossing over occurs between:
a) Sister chromatids of homologous chromosomes.
b) Non- sister chromatids of homologous chromosome
c) Sister chromatids of non-homologous chromosomes
d) Non-homologous chromatids of homologous chromosomes
43. Which of the following is not true for anaphase?
a) Golgi body and ER are reformed b) Spindle poles move farther apart
c) Chromosome move to opposite poles d) Centromere split ad chromatid separate
44. In cell cycle which of the following is the correct sequence?
a) S – G1 – G2 – M b) G1 – S – G2 – M c) S – G2 – G1 – M d) M – S – G1 – G2
45. ‘G0’ State of cells in eukaryotes cell cycle denotes:
a) Check point before entering the next phase.
b) Pausing in the middle of a cycle to cope with temporary delay.
c) Death of cell.
d) Exit of cells from cell cycle.
46. Chromatin fiber condense in:
a) Prophase stage b) Metaphase stage
c) Anaphase stage d) Telophase stage
47. Which spindle fibre has smallest size?
a) chromosomal fibre b) Supporting fibre
c) Interzonal fibre d) Continuous fibre
48. Which statement is false?
a) Cells that do not divide are usually arrested in the G 2 phase
b) Within the centrosome of an animal cell there are pair of centrioles
c) The kinetochore is the point of attachment of the spindle fibre to the chromaitid
d) In anaphase stage the sister chromatids begins to separate.
49. Anastral mitosis is found in:
a) Animals b) Higher plants c) Bacteria d) Cyanobacteria
50. Which of the following represents the best stage to view the shape, size and number of chromosomes?
a) Prophase b) Metaphase c) Interphase d) Telophase
51. Cells which are not dividing are likely to be at:
a) G1 b) G2 c) G0 d) S phase
52. Select the correct statement about G 1 phase:
a) Cell is metabolically inactive
b) DNA in the cell does not replicate
c) It is not a phase of synthesis of macromolecules
d) Cell stops growing
53. Which of the events listed below is not observed during mitosis?
a) Chromatin condensation
b) Movement of centrioles to opposite poles
c) Appearance of chromosomes with two chromatids joined together at the centromere
d) Crossing over
54. Meiosis results in diploid organisms:
a) Production of gametes b) Reduction in the number of chromosomes
c) Introduction of variation d) All of the above
55. At which stage of meiosis does the genetic constitution of gametes is finally decides?
a) Metaphase – I b) Anaphase – II c) Metaphase – II d) Anaphase – I
56. Meiosis occurs to organisms during:
a) Sexual reproduction b) Vegetative reproduction
c) Both sexual and vegetative reproduction d) None of the above
57. During Anaphase – I of meiosis:
a) Homologous chromosomes separate b) Non- homologous chromosomes separate
c) Sister chromatids separate d) Non-sister chromatids separate
58. Mitosis is characterized by:
a) Reduction division b) Equal division
c) Both reduction and equal division d) Pairing of homologous chromosomes
59. A bivalent of meiosis – I consists of:
a) Two chromatids and one centromere b) Two chromatids and two centromere
c) Four chromatids and two centromere d) Four chromatids and four centromere
60. In which phase of the cell cycle, the proteins for spindle formation are synthesized?
a) G1 Phase b) G2 Phase c) S-Phase d) Anaphase
61. When does pairing occur in chromosome (meiosis)?
a) Leptotene b) Zygotene c) pachytene d) Diakinesis
62. The most active stage of cell cycle is:
a) Prophase b) Metaphase c) Telophase d) Interphase
63. Which of the following is the method of cytokinesis in plant cell?
a) By cell plate formation b) By constriction
c) By phragmoplast d) Both (a) and (c)
64. In which stage of cell cycle, nucleus becomes bigger?
a) G1 b) G2 c) S D) M
65. What happens in interkinesis?
a) DNA replication b) Chromosome duplication
c) Preparation of second meiotic division d) Resting stage
66. The drug colchicine has inhibitory effect in which stage of the cell cycle?
a) G1 b) S c) M d) G2
67. How much part of cell cycle is formed by interphase?
a) 50% b) 70% c) 10% d) 90%
68. How many chromosomes will be in cells of human produced by meiosis?
a) 46 b) 69 c) 23 d) 100
69. Which division maintains genetic similarity?
a) Mitosis b) Meiosis c) Amitosis d) Reduction division
70. Ribonuclease, a mitotic poison, inhibits cell cycle in:
a) Interphase b) Prophase c) Metaphase d) Anaphase
71. The most primitive type of mitosis is:
a) Amitosis b) Crypto mitosis c) Endomitosis d) Zygotic mitosis
72. Dinomitosis occurs in:
a) Prokaryotes b) Mesokaryotes c) Eukaryotes d) Akaryotes
73. Genetic information is transferred from zygote to all body cells by:
a) Meiosis b) Amitosis c) Endomitosis d) Mitosis
74. Division of cell without recognizable chromosomes is:
a) Amitosis b) Mitosis c) Meiosis d) Meiosis-II
75. Meiosis does not occurs in:
a) Ovule b) Anther c) Microsporangium d) Shoot tip
76. Which of the two events restore the normal number of chromosomes in life cycle?
a) Mitosis and meiosis b) Meiosis and fertilization
c) Fertilization and mitosis d) Only meiosis
77. Division of nucleus is indirect in:
a) Mitosis b) Meiosis c) Amitosis d) Both (a) and (b)
78. The number of meiosis required to produce 100 megaspore in angiosperm is:
a) 125 b) 100 c) 25 d) 75
79. Meiosis which occurs at the time of spore formation is called:
a) Zygotic meiosis b)Haplontic meiosis
c) Terminal meiosis d) Intermediate meiosis
80. Tetrad formation in meiosis occurs in:
a) Leptotene b) Zygotene c) Pachytene d) Diplotene
81. The longest phase in meiotic division is:
a) Prophase – I b) Metaphase – I c) Prophase – II d)Anaphase – I
82. Separation of homologous chromosomes during Anaphase – I is called:
a) Synapsis b) Disjunction c) Non-disjunction d) Crossing over
83. Cell plate formation starts from:
a) Phragmoplast b) Epiplast c) Tonoplast d) Protoplast
84. The time period between meiotic I and meiotic II cell division is known as:
a) Growth phase b) First gap period c) Interkinesis d) Interphase
85. Which of the following statements is not correct regarding colchicines?
a) It prevents assembly of microtubules c) It inhibits chromosome replication
c) It is an alkaloid d) It is called as mitotic poison
86. The spindle fibre unite with which structure of the chromosomes:
a) Chromocenter segregate b) Chromomere
c) Centromere d) Centriole
87. During diplotene stage of meiosis:
a) Chromosomes replicate b) Chromosome segregate
c) Homologous chromosomes pair d) Chiasmata are observed
88. In pachytene stage of meiosis, the chromosomes appear.
a) Three – stranded b) Four –stranded c) Single – stranded d) Double – stranded
89. Which of the following is the longest phase of meiosis?
a) Prophase – I b) Anaphase – I c) Prophase – II d) Metaphase – II
90. Which of the following can be classified as G0 cells?
a) Neurons b) Fibroblasts c) Monocytes d) Lymphocytes

Answer Key
1– d 2– b 3– a 4– c 5 – c 6– a 7– c 8– a 9– c 10 – d
11 – d 12 – d 13 – a 14 – c 15 – b 16 – c 17 – a 18 – a 19 – a 20 – a
21 – a 22 – d 23 – d 24 – a 25 – a 26 – a 27 – b 28 – a 29 – d 30 – c
31 – d 32 – d 33 – c 34 – d 35 – c 36 – a 37 – b 38 – d 39 – a 40 – c
41 – d 42 – b 43 – a 44 – b 45 – d 46 – a 47 – c 48 – a 49 – b 50 – b
51 – c 52 – b 53 – d 54 – d 55 – d 56 – a 57 – a 58 – b 59– c 60 – b
61 – b 62 – d 63 – d 64 – c 65 – c 66 – c 67 – d 68 – a 69 – a 70 – a
71 – b 72 – b 73 - d 74 – a 75 – d 76 – b 77 – d 78 – b 79 – d 80 – c
81 – a 82 – b 83 – a 84 – c 85 – b 86 – c 87 – d 88 – b 89 – a 90 – a