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5a. Echo Evaluation of Mitral Stenosis, DR Azri

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ECHOCARDIOGRAPHIC EVALUATION

OF MITRAL STENOSIS

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• Echo memaikan peranan penting dalam
evaluasi MS
• Berperan dalam menentukan diagnosis dan
derajat stenosis
Etiologi Mitral Stenosis

 Rheumatic

 Degenerative

 Congenital MS

 Other: Systemic lupus , Infiltrative disease,


Carcinoid heart disease , Drug-induced.
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Gambaran Anatomis
 Rheumatic
Commissural fusion
Leaflet thickening
Chordal shortening and fusion
Superimposed calcification.

 Degenerative
Annular calcification.
Rarely leaflet thickening & calcification at base.

 Congenital
Subvalvular apparatus abnormalities.

 Systemic lupus , Carcinoid & Drug induced

Leaflet thickening & restriction are common here.


Commissures are rarely fused.
2D ECHO
• Normal: AML & PML membuka
dengan maximal excursion pada
leaflet tips.

• Pada rheumatic MS: doming


motion of AML with restriction of
motion at tips – Hockey Stick
appearance.

• Merubah mitral apparatus dari


tubular channel menjadi corong
(funnel-shaped orifice).
2D ECHO
 Commissural fusion
Assessed in PSAX view
Rheumatic etiology
Complete fusion - severe MS.

 Leaflet thickening
Asssessed in PLAX

 Chordal thickening & fusion in


PLAX , Apical 4 Chamber views
M mode of mitral leaflets
M Mode ECHO

• Peningkatan echogenitas leaflets.

• Decreased excursion & reduced


separation of AML dan PML.

• Reduced diastolic E-F slope of mitral


closure
Normal EF slope is > 60mm/sec
If < 10 mm/sec indicate severe MS
Assessment of Mitral Stenosis Severity
Level 1 Recommendations: (metode yang direkomendasikan pada
semua pasien stenosis)
Pressure gradient.
MVA Planimetry.
Pressure half-time.

Level 2 Recommendations: (metode yang dipakai apabila dibutuhkan


informasi tambahan)
Continuity equation.
Proximal isovelocity surface area (PISA).
Stress echocardiography.

EAE/ASE RECOMMENDATIONS
Pressure gradient
• Diastolic pressure gradient dihitung berdasarkan persamaan
Bernoulli : ∆P = 4V2

• Berkorelasi baik dengan pengukuran invasif (transseptal


catheterization)

• Gradient diukur pada apical window.

• Continuous wave doppler lebih disukai

• Color doppler digunakan untuk mengidentifikasi eccentric mitral


jets.
Pressure gradient

• Dihitung maximal & mean gradient.

• Mean gradient is relevant hemodynamic finding.

• Maximal gradient didapat dari peak mitral velocity, yang


dipengaruhi oleh left atrial compliance & fungsi diastolik LV.

• In AF: diambil rata-rata dari 5 pengukuran.

• Dicatat HR saat pengambilan gradients.


PRESSURE GRADIENT

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MVA by Planimetry
• Reference measurement of MVA.
• Dilakukan dengan cara tracing langsung orificium mitral dengan
memasukkan commisura yang terbuka pada PSAX view saat mid-
diastole
• Cross section area (CSA) diukur pada leaflet tips.
MVA by Planimetry

• Gain setting diatur sehingga cukup jelas terlihat kontur dari


orifisium mitral
• Excessive gain setting dapat menyebabkan underestimation area
katup.

• 3D echo imaging dapat meningkatan akurasi planimetri


Both commissures are fused Unicommissural opening

Bicommissural opening
Advantages of planimetry

 Merupakan pengukuran langsung MVA.


 Tidak tergantung pada kondisi flow maupun compliance dari ruang
jantung.

Disadvantage

 Tidak akurat pada poor


acoustic window dan
kalsifikasi katup yang berat
Pressure half-time (PHT) or T1/2
• PHT adalah interval waktu (msec) antara saat gradient mitral
maksimum pada early diastole dengan saat dimana gradient tinggal
setengahnya.
• MVA didapatkan dengan rumus: MVA = 220/PHT
• PHT didapatkan dengan melakukan tracing pada deceleration slope
E-wave pada spectral

display doppler transmitral

flow.
Measuring T1/2 with a bimodal slope of E-
wave

Deceleration slope in mid-diastole rather than early to be traced


MS with AF pts

Tracing should avoid mitral flow from short diastoles and


average of different cardiac cycles to be taken
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Continuity equation
• Continuity equation is based on the conservation of mass.
• Filling volume of diastolic mitral flow is equal to aortic SV.

• MVA = π D2 X VTI aortic


4 VTI mitral
D - diameter of the LVOT (cm)
VTI – Velocity Time Integral (cm)

• SV can also be estimated from


the pulmonary artery.
Disadvantages

 Memerlukan multiple measurements dan and meningkatkan


kemungkinan untuk terjadinya error.

 Tidak bisa dipakai pada AF atau significant MR or AR.


Mitral leaflet separation (MLS) index

• Distance b/w tips of mitral leaflets in PLAX & four-chamber view in


diastole.
• Value < 0.8 cm predict severe mitral stenosis.
• Value > 1.1 to 1.2 cm indicate mild MS.
MITRAL STENOSIS SEVERITY

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Assessment of mitral valve anatomy by
Wilkins score
• Important for choice of intervention.

• Parameters assessed are valve mobility , thickening , calcification ,


subvalvular pathology.

• Each parameter given score 1 to 4.

• Total score is sum of four individual scores.

• Score ≤ 8 are excellent candidates for BMV.

• Score ≥ 12 are less likely to have satisfactory result.


Wilkins score

Wilkins et al. Br Heart J 1988;60:299-308


Secondary features of MS

• Menyebabkan peningkatan LA pressure.

• LA and LA appendage akan mengalami dilatasi.

• Meningkatkan risiko pembentukan trombus thrombus akibat stasi


darah.

• Dilated RA ,RV and paradoxical septal motion dapat terjadi akibat


pulmonary hypertension.
LA clot & spontaneous echo contrast
THANK YOU

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