Protocol For A Systematic Review of Policies Programs or Interventions Designed To Improve Health and
Protocol For A Systematic Review of Policies Programs or Interventions Designed To Improve Health and
Protocol For A Systematic Review of Policies Programs or Interventions Designed To Improve Health and
Abstract
Background: Relative to their counterparts in the general population, young people who leave, or transition out of,
out-of-home (OOHC) arrangements commonly experience poorer outcomes across a range of indicators, including
higher rates of homelessness, unemployment, reliance on public assistance, physical and mental health problems
and contact with the criminal justice system. The age at which young people transition from OOHC varies between
and within some countries, but for most, formal support ceases between the ages of 18 and 21.
Programs designed to support transitions are generally available to young people toward the end of their OOHC
placement, although some can extend beyond. They often encourage the development of skills required for
continued engagement in education, obtaining employment, maintaining housing and general life skills. Little is
known about the effectiveness of these programs or of extended care policies that raise the age at which support
remains available to young people after leaving OOHC. This systematic review will seek to identify programs and/or
interventions that improve outcomes for youth transitioning from the OOHC system into adult living arrangements.
* Correspondence: david.taylor@monash.edu
1
Department of Social Work, Monash University, 900 Dandenong Road,
Caulfield East, VIC 3145, Australia
2
Centre for Evidence and Implementation, 33 Lincoln Square South, Carlton,
VIC 3053, Australia
Full list of author information is available at the end of the article
© The Author(s). 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License,
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The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the
data made available in this article, unless otherwise stated in a credit line to the data.
Taylor et al. Systematic Reviews (2021) 10:240 Page 2 of 9
Methods: This review will identify programs, interventions and policies that seek to improve health and wellbeing
of this population that have been tested using robust controlled methods. Primary outcomes of interest are
homelessness, health, education, employment, exposure to violence and risky behaviour. Secondary outcomes are
relationships and life skills. We will search, from January 1990 onwards, MEDLINE, EMBASE, PsycINFO, ERIC, CINAHL,
Cochrane CENTRAL, SocINDEX, Sociological Abstracts, Social Services Abstracts, NHS Economic Evaluation Database
and Health Technology Assessment. Grey literature will be identified through searching websites and databases, e.g.
clearing houses, government agencies and organisations known to be undertaking or consolidating research on
this topic area. Two reviewers will independently screen all title and abstracts and full text articles with conflicts to
be resolved by a third reviewer. Data extraction will be undertaken by pairs of review authors, with one reviewer
checking the results of the other. If more than one study with suitable data can be identified, we plan to undertake
both fixed-effects and random-effects meta-analyses and intend to present the random-effects result if there is no
indication of funnel plot asymmetry. Risk of bias will be assessed using tools appropriate to the study methodology.
Quality of evidence across studies will be assessed using the Grading of Recommendations, Assessment,
Development and Evaluation (GRADE) methodology.
Discussion: Previous reviews were unable to identify any programs or interventions, backed by methodologically
rigorous research, that improve outcomes for this population. This review seeks to update this previous work, taking
into account changes in the provision of extended care, which is now available in some jurisdictions.
Systematic review registration: PROSPERO CRD42020146999
Keywords: Systematic review, Transitions, Out-of-home care, Aftercare, Leaving Care, Ageing out
22]. Considering this, in some jurisdictions, one policy Criteria for considering studies for this review
response has been to raise the age at which young Studies will be selected according to the following cri-
people can transition, thereby extending the support teria: population, intervention, comparator, outcome and
available [4, 23, 24]. study design.
Transition support programs are generally available to
young people toward the end of their care placement, al- Population
though some extend beyond. They often encourage the Youth aged between 16 and 25 who are:
development of skills required for continued engage-
ment in education, obtaining employment, maintaining Not living with their birth parents/family; AND
housing and general life skills [17, 20]. Are in foster care/out-of-home care/public care/
Fifteen years ago, Donkoh et al. conducted the first looked after (UK)/state care/government care; AND
methodologically rigorous systematic review of inde- Have been placed in care due to concerns related to
pendent living programs for young people leaving out- child maltreatment, neglect or risk of child
of-home care and were unable to find any studies that maltreatment, relinquishment, or lack of provision
met their inclusion criteria [17]. In the intervening of support; AND
period, a number of reviews have explored various as- Who are transitioning from care into adult living
pects of policies, programs or interventions for youth arrangements.
transitioning from care but have suffered from a range
of weaknesses in either methodology or scope. Intervention
Some reviews have limited their scope, either to par- Policies, programs or interventions that:
ticular geographies [20], or to interventions delivered
whilst youth were in care [17, 25], or to independent liv- Provide support and/or assistance to help youth
ing programs [17, 26, 27]. Some focused on a narrow prior to leaving care and/or as they transition and/or
range of outcomes [27, 28]. Others have methodological after they leave care;
weaknesses, such as not conducting a systematic search Are delivered in the community;
[22], not applying a methodological filter or addressing Support young people transition from their
the risk of bias of included studies [25, 29], or they failed country’s statutory out-of-home care systems into
to critically appraise the effectiveness of the policy or adult living.
practice interventions included [26, 27, 30–32]. This re-
view seeks to update and build upon this previous work Comparator
by additionally investigating the effectiveness of policies The following comparisons will be included: interven-
that provide the option to extend out-of-home care be- tion/services as usual (i.e. what an individual would have
yond 18 years old, thereby increasing the age at which received in the absence of the intervention), another
young people transition. intervention (i.e. another policy, program or intervention
The aim of this systematic review is to assess the ef- for young people leaving out-of-home care), no interven-
fectiveness of programs and/or interventions designed to tion or wait-list control (i.e. individuals waiting to be in-
improve outcomes for youth transitioning from the out- cluded in the intervention).
of-home care system into adult living arrangements. The
proposed systematic review question is: Outcome(s)
What programs, interventions or services are effective Outcomes of interest include the following, which must
at improving health and psychosocial outcomes for be measured at least three months following the age at
young people leaving the out-of-home care system? which eligibility for standard out-of-home care termi-
nates in the jurisdiction in which the study took place.
Methods Outcomes will be considered if they were obtained from
The systematic review has been registered with the Inter- linked administrative data sources (i.e. employment,
national Prospective Register of Systematic Reviews (PROS- health or other records), validated measures (e.g. conflict
PERO, http://www.crd.york.ac.uk/PROSPERO, registration tactics scale) and non-validated measures (e.g. self-
number: CRD42020146999). reported homelessness) administered by interview or
The present protocol is being reported in accordance survey.
with the reporting guidance provided in the Preferred
Reporting Items for Systematic Reviews and Meta- Primary
Analyses Protocol (PRISMA-P) [33] (see Additional file
1). The final review will be reported in accordance with Homelessness—we will include any homelessness/
the updated PRISMA 2020 statement [34] . housing-related outcomes, including any
Taylor et al. Systematic Reviews (2021) 10:240 Page 4 of 9
measurement that allows us to determine whether difference estimation, synthetic control group methods,
or not an individual has or does not have a studies based on covariate matching, propensity score-
permanent place to live; based methods, doubly robust methods, regression ad-
Health—we will include any health-related outcomes justment, regression discontinuity designs and instru-
or measures of service usage, including but not lim- mental variable estimation; and economic evaluation
ited to emergency department presentations, hospi- methodologies including cost-benefit analysis, cost-
talisations and any measure of mental health utility analysis, cost-effectiveness analysis and cost-
conditions or symptoms; analysis.
Education—we will include any education-related Economic evaluations and qualitative studies will be
outcomes, including but not limited to measurement included if they are conducted as part of a qualifying
of high school or equivalent completion, high school study and will be used only to inform or deepen our un-
grades, enrolment in or attainment of a trade/voca- derstanding of the quantitative findings.
tional qualification and enrolment in or attainment
of a university qualification; Information sources and search strategy
Employment—we will include any employment- The following databases will be searched for studies
related outcomes, including but not limited to meas- published from January 1990 onward using strategies in-
urement of whether an individual is employed, their cluded in (Additional file 2):
wages or utilises unemployment benefits;
Exposure to violence (as either victim or Cochrane CENTRAL
perpetrator)—we will include any exposure to CINAHL
violence-related outcomes, including but not limited ERIC
to measurement of crime perpetration (i.e. whether PsycINFO
or not an individual has been arrested, convicted, or MEDLINE
spent time in a locked setting, e.g. jail/prison) or EMBASE
crime victimisation (i.e. where the individual was the Sociological Abstracts
victim); Social Services Abstracts
Risky behaviour—we will include any risky SocINDEX
behaviour-related outcomes, including but not lim- NHS Economic Evaluation Database
ited to measurement of illicit drug use, alcohol Health Technology Assessment
abuse, risky sexual behaviour, positive sexually trans-
mitted infection tests and either the onset or delay Supplementary searches
of teen pregnancy. Websites and databases from clearinghouses, govern-
ment agencies and organisations known to be undertak-
Secondary ing or consolidating research in this area from the USA,
Europe, Australia, Canada and New Zealand will be ex-
Relationships—we will include any relationships- amined for unpublished material, including but not lim-
related outcomes, including but not limited to meas- ited to:
urement of whether an individual has attained or
maintained supportive relationships with others, in- Social Care Online (SCIE)
cluding mentors, peer mentors or supportive peers; International Research Network on Transitions to
Life skills—we will include any life skills-related out- Adulthood from Care
comes, including but not limited to measurement of Analysis and Policy Observatory
the attainment of competencies required for inde- Australian Institute of Family Studies
pendent living; these include, but are not limited to, Chapin Hall at the University of Chicago
learning how to budget, attain essential services and California Evidence-Based Clearinghouse for Child
perform essential household tasks. Welfare
Washington State Institute for Public Policy
Study design(s)
The following experimental and quasi-experimental In addition to the organisations listed above, we will
study designs will be included: randomised controlled search the websites of organisations affiliated with au-
trials (RCTs) including individual RCTs, cluster RCTs, thors or included studies.
Step-Wedge designs with random time allocation and The reference lists of previous systematic reviews iden-
non-equivalent control group designs using parallel co- tified in the search process will be reviewed alongside
horts that adjust for baseline equivalence; difference-in- those reviews already known to the authors. References
Taylor et al. Systematic Reviews (2021) 10:240 Page 5 of 9
of included studies will also be screened for eligibility. mean difference. Where different measures are used to
Additionally, authors of included studies will be con- examine primary outcomes, we will calculate the stan-
tacted by email to ascertain if they are aware of any add- dardised mean difference if possible. Where data from
itional unpublished literature that may meet the the same outcome are reported in different studies as di-
inclusion criteria for this review. chotomous or continuous data, we will transform these
(if appropriate) to enable pooled estimates of effect.
Language of publication If effect sizes are missing or displayed in ways that do
No restrictions will be placed on the language of not allow us to determine a pooled estimate, we will use
publication. the Campbell Collaboration effect size calculator [36]. If
we are not able to calculate an effect size in this manner,
Data collection and management we will contact the authors and seek to obtain the infor-
Citations identified from the search strategy will be mation required for us to do so.
imported into the online systematic review application In accordance with the Cochrane Handbook for System-
Covidence [35] for screening. Following PRISMA guide- atic Reviews of Interventions, we will try to maximise the
lines, a flowchart will be provided demonstrating the in- likelihood of being able to quantitatively synthesise primary
puts and results of each stage of the review process. and secondary outcomes across studies using a meta-analysis
[37]. If more than one study with suitable data can be identi-
Study selection fied, we intend to perform a meta-analysis if the population,
Title and abstracts will be reviewed independently by intervention, comparison and outcomes are similar enough
two review authors, with a third reviewer resolving con- to be reasonably combined or can be standardised for com-
flicts when they arise. Two review authors will inde- parison. To make this judgement, we will group included
pendently read the full-text versions of all potentially studies by outcome domain and study design, whilst consid-
eligible studies that they have selected, and a third re- ering the intervention type, population, comparator, outcome
viewer will resolve conflicts when necessary. The eligibil- measure and timing of outcome measurement.
ity criteria are included in Table 1. We plan to undertake both fixed-effects and random-
effects meta-analyses and intend to present the random-
Data extraction effects result if there is no indication of funnel plot
Data extraction will be undertaken by pairs of review au- asymmetry. These models will allow us to estimate the
thors, with one reviewer checking the results of the pooled effect size and its 95% confidence interval for
other. Data will be extracted into an online form devel- each outcome. For both approaches, we will perform a
oped for this review. The following information will be meta-analysis using the longest follow-up period possible
obtained: study design, study outcomes, sample size, lo- for each outcome.
cation, study timeframe, study population, population Data from randomised and non-randomised trial de-
demographics, intervention details, effect sizes, imple- signs will not be pooled. We will also not pool data from
mentation outcomes as well as information required to non-randomised studies of different study designs. We
conduct risk of bias assessments. Authors of included will seek to undertake sensitivity analysis, if appropriate
studies will be contacted by email to request any re- based on decisions made during the review process.
quired information that is unavailable in print. For each outcome, we will explore heterogeneity by pre-
paring box plots, forest plots and examining the I2 statistic.
Data analysis Evidence of heterogeneity—where the p value < 0.1 and I2
We will synthesise data around each of our primary out- statistic is greater than 75%—will be highlighted in the
come domains (as defined in the “Criteria for consider- reporting of that outcome. Thresholds of low, medium and
ing studies for this review” section) as well as high heterogeneity will be assigned to I2 values of 25%, 50%
considering author affiliation, funding sources, conflicts and 75% [38]. This analysis will be conducted using the R
of interest, individual versus group delivery and setting. Project for Statistical Computing [39].
If sufficient studies are identified, subgroup analysis will If the conditions for conducting a meta-analysis are
be undertaken based upon the following characteristics: not met, we will describe and synthesise study findings
(a) study design: randomised control trials vs. non- narratively in line with guidance from the SWiM report-
randomised control trials, (b) age at which statutory out- ing guideline [40]. The data from each included study
of-home care support ceases: 18 vs. greater than 18 and (e.g. study characteristics, context, exposures, outcomes
(c) gender. and findings) will be used to build summary of findings/
For binary outcomes, we will calculate a risk ratio and evidence tables including an overall description of in-
a 95% confidence interval. For continuous data, if a con- cluded studies. Studies will be grouped, and results syn-
sistent outcome measure is used, we will calculate the thesised by outcome domain, stratified by study design,
Taylor et al. Systematic Reviews (2021) 10:240 Page 6 of 9
guidelines suggested by the Cochrane and Campbell international studies of out-of-home care systems and
Economics Methods Group [44]. The quality of evidence policies have emphasised that studies conducted in dif-
across outcomes that can be synthesised in a meta- ferent welfare state regimes may represent different ways
analysis will be assessed as either very low, low, moder- of defining and conceptualising out-of-home care, its
ate or high using the GRADE methodology [45]. key target population and key aspects of the care experi-
ence [4, 16, 46]. In synthesising these as part of this re-
Discussion view, detailed information on the context dependence of
Reflecting its place as an emergent policy issue, the vol- findings may therefore get lost, highlighting the need for
ume of research published on care leavers has increased a locally driven translation process of results and their
substantially in the last 20 years, but this literature has potential implications for policy and practice in specific
not been the subject of high-quality synthesis. Therefore, locations.
it is an appropriate time for a systematic review to in- The results of this review will be disseminated though
form ongoing policy and practice discussions about how publication in a report by the funder, conference presen-
best to support young people transitioning from care tations and in peer reviewed publications. Any future
and to shape future research. amendments to this protocol in the course of the review
This review has a number of advantages over previ- will be updated in PROSPERO and reported in the pub-
ously published work on this topic, including (a) a sys- lished review.
tematic search of a wide range of databases with no
language restrictions, (b) the use of inclusion criteria Abbreviations
GRADE: Grading of Recommendations, Assessment, Development and
that prioritise studies with high-quality methodologies, Evaluation; OOHC: Out-of-home care; QED: Quasi-experimental design;
(c) the selection of outcomes that reflect health and psy- RCT: Randomised control trial; SWiM: Synthesis without meta-analysis
chosocial wellbeing, (d) the inclusion of policy alongside
individual or group-level interventions and (e) the use of Supplementary Information
the GRADE approach to assess the quality of evidence, The online version contains supplementary material available at https://doi.
report results and support knowledge translation. org/10.1186/s13643-021-01792-5.
Author details 17. Donkoh C, Underhill K, Montgomery P. Independent living programmes for
1
Department of Social Work, Monash University, 900 Dandenong Road, improving outcomes for young people leaving the care system. Cochrane
Caulfield East, VIC 3145, Australia. 2Centre for Evidence and Implementation, Database Syst Rev. 2006;8 Available from: http://doi.wiley.com/10.1002/14
33 Lincoln Square South, Carlton, VIC 3053, Australia. 3Institute for 651858.CD005558.pub2.
Implementation Science in Health Care, University of Zurich, 18. Havlicek J, Garcia A, Smith DC. Mental health and substance use disorders
Universitätstrasse 84, 8006 Zurich, Switzerland. 4School for Policy Studies, among foster youth transitioning to adulthood: past research and future
University of Bristol, 8 Priory Rd, Bristol BS8 1TZ, UK. 5The Fostering Network, directions. Child Youth Serv Rev. 2013;35(1):194–203. Available from: https://
87 Blackfriars Road, London SE1 8HA, UK. www.ncbi.nlm.nih.gov/pmc/articles/PMC3677527/pdf/nihms414350.pdf.
https://doi.org/10.1016/j.childyouth.2012.10.003.
Received: 3 December 2020 Accepted: 13 August 2021 19. Gypen L, Vanderfaeillie J, De Maeyer S, Belenger L, Van Holen F. Outcomes
of children who grew up in foster care: systematic-review. Child Youth Serv
Rev. 2017;76:74–83. Available from:. https://doi.org/10.1016/j.childyouth.2017.
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