M.SC Integrated Biotechnology AY 2019 2020
M.SC Integrated Biotechnology AY 2019 2020
M.SC Integrated Biotechnology AY 2019 2020
TECHNOLOGY
PO_06: Having problem solving ability- to assess social issues (societal, health,
safety, legal and cultural) and engineering problems
PO_12: Having interest and recognise the need for independent and lifelong
learning
APO_06: Having an ability to use the social media effectively for productive
use
CREDIT STRUCTURE
Category Credits
University core (UC) 66
Programme core (PC) 70
Programmme elective (PE) 62
University elective (UE) 12
Bridge course (BC) 0
Total credits 210
DETAILED CURRICULUM
University Core
Programme Core
Programme Elective
Humanities courses
Sl.No Code Title L T P J C
1 HUM1001 Fundamentals of Cyber Laws 3 0 0 0 3
2 HUM1002 Business Laws 3 0 0 0 3
3 HUM1003 Basic Taxation for Engineers 3 0 0 0 3
4 HUM1004 Corporate Law for Engineers 3 0 0 0 3
5 HUM1005 Cost Accounting for Engineers 3 0 0 0 3
6 HUM1006 Business Accounting for Engineers 3 0 0 0 3
7 HUM1007 Contemporary Legal Framework for Business 3 0 0 0 3
8 HUM1009 International Business 3 0 0 0 3
9 HUM1010 Foreign Trade Environment 3 0 0 0 3
10 HUM1011 Export Business 3 0 0 0 3
11 HUM1012 Introduction to Sociology 3 0 0 0 3
12 HUM1013 Population Studies 3 0 0 0 3
13 HUM1021 Ethics and Values 2 0 0 0 2
14 HUM1022 Psychology in Everyday Life 2 0 0 4 2
15 HUM1023 Indian Heritage and Culture 2 0 0 4 2
16 HUM1024 India and Contemporary World 2 0 0 4 2
17 HUM1025 Indian Classical Music 1 0 2 4 1
18 HUM1033 Micro Economics 3 0 0 0 3
19 HUM1034 Macro Economics 3 0 0 0 3
Contents
1. It can be a theoretical analysis, modeling & simulation, experimentation & analysis,
prototype design, correlation and analysis of data, software development, applied
research, and any other related activities.
2. The project can be for one or two semesters based on the completion of the required
number of credits as per the academic regulations.
4. Carried out inside or outside the university, in any relevant industry or research
institution.
Mode of Evaluation: Periodic reviews, Presentation, Final oral viva, Poster submission
Recommended by Board of 04.03.2016
Studies
Approved by Academic Council 40th AC Date 18.03.2016
Module 1:
Biochemistry: Foundation of biochemistry, Carbohydrates, Amino acids and Proteins, Lipids and
Nucleic acids. Analytical Techniques in Biotechnology: Lab Practices and Sampling, Analytical
Lab, Standard Operating Procedures, Physico-chemical analyses, Spectrometry, Electrophoresis
and chromatography, Mass Spectrometry and NMR.
Module 2:
Cell Biology and Genetics: Cell structure and function, Transport across cell membranes, Cell
signalling, motility and integration, Mechanisms of inheritance, Evolution and genetic
applications. Molecular Biology: Chromosomes, DNA, Transcription, translation, Retroviruses
and recombination - transformation, conjugation, transduction.
Module 3:
Immunology: The Immune System, Humoral Immune responses, Cellular Immune responses,
Immunity to infection, Immunology of transplantation. Genetic Engineering: Concepts of
Recombinant DNA technology, Tool enzymes, Vectors, Gene cloning strategies, Polymerase
chain reaction.
Module 4:
Animal Biotechnology: Introduction to Physiology, Neurotransmitters and Nervous system,
Animal Cell Technology and its applications, Animal Reproductive Biotechnology, Transgenic
animals & transgenic engineering.
Module 5:
Microbiology: Tools in Microbiology, Morphology and Taxonomy, metabolisms of
microorganism, Microbial growth, Applied Microbiology. Plant Biotechnology: Plant growth and
development, Plant genome Organization and Tissue culture, Plant transformation, transgenic
plants, Marker technology.
Module 7
Plant Biotechnology: Plant growth and development, Plant genome Organization and Tissue
culture, Plant transformation, transgenic plants, Marker technology.
Recommended by Board of Studies 04.03.2016
Approved by Academic Council 40th AC 40th AC 18-03-2016
Text Book(s)
1. Peter Norton, 2017, Introduction to Computers, 7th Edition, Tata McGraw Hill Publications.
2. Joan Lambert, and Curtis Frye, 2017 Microsoft Office 2016 Step by Step, Microsoft Press
Reference Books
1. Rajaraman V, and Adabala N, 2014, Fundamentals of Computers, PHI Publication
Mode of Evaluation: Assignments, Continuous assessment tests and Final assessment test.
List of Experiments SLO: 2,8
1. Unix and DOS commands
2. Creating and Formatting Word document
3. Creating and Manipulating Tables in a document
4. Inserting any Graphics in a document
5. Create a Personal Resume
6. Using the Excel Formula and Functions
7. Representing Data in a Chart
8. Excel Using Pivot Table
9. Excel Using Functions
10. Working with Design Templates and Auto Content wizards by using
PowerPoint
11. Formatting and editing slides
12. PowerPoint Slide design
13. Slide transition effects
Reading text from files, file content and file name, dealing with newlines, writing text to files,
closing files.
Text Book(s)
1. Jason Cannon, 2014, Command Line Kung Fu: Bash Scripting Tricks, Linux Shell
Programming, First edition, Create Space Independent Publishing Platform.
2. Dr. Martin Jones, 2013, Python for Biologists: A complete programming course for
beginners, First edition, Create Space Independent Publishing Platform.
Reference Books
1. Martin C, 2018, Python: The Complete Reference, 4 edition, McGraw Hill Publisher.
2. Richard Blum & Christine Bresnahan, 2015, Linux Command Line and Shell Scripting
Bible, 3ed Wiley publisher.
List of Challenging Experiments
1. Basic Bash Shell commands
2. Creating Bash Script
3. Understanding Shell configuration files
4. Control Statements
5. Conditional Statements
6. Python program to calculate AT content and Complement of a DNA
Sequence.
7. Splitting of Genomic DNA
8. Processing DNA in a file
THEORY
Textbook/ Workbook
THEORY
PRACTICE SESSIONS:
Reference Books
1. Maclean Joan and Lynch Tony (2013) Study Speaking, CUP.
2. Thill John and L. Bove Courtland (2016) Excellence in Business Communication, Pearson
Publications
3 Khera Shiv 2013 (Reprint 2019) You Can Win: New Delhi, Bloomsbury India, New Delhi
Mode of Evaluation: Quizzes, Presentation, Discussion, Role play, Assignments and FAT
List of Challenging Experiments (Indicative)
1 Error detection in paragraph 6 hours
2 Role plays on professional situations 10 hours
3 Discussing a Case on communication skills 7 hours
4 Academic listening and note taking 7 hours
5 Report Writing 10 hours
6 Guessing unfamiliar words from the prescribed text 5 hours
Total Laboratory Hours 45 hours
Mode of Evaluation: Quizzes, Presentation, Discussion, Role Play, Assignments & FAT
Recommended by Board of Studies 08-06-2019
Approved by Academic Council No. 55 Date 13-06-2019
THEORY
Module:1 Verbal-Logic & Reasoning 4 hours
Verbal reasoning tests assess the learner’s understanding and comprehension skills.
Activity: Interpreting short texts.
Module:2 The Art of Paraphrasing 2 hours
A restatement of the meaning of a text or passage using other words.
Activity: Paraphrasing different articles & Research papers
Module:3 Text-based Analysis 6 hours
The Thousand Faces of Night by Githa Hariharan
Activity: Summarizing/ note making & drawing inferences from the text
Module:4 Research Paper Writing 3 hours
Structure of a Research paper; Plagiarism
Activity: Practice on Research Paper writing.
PRACTICE-SESSIONS
Activity-1 Vocalics 4 hours
The learners will undergo training in vocalics which are rate, or speed at which the person speaks,
pitch, inflection and variety in the voice, volume, being loud or soft, and articulation and
pronunciation, or how correctly and clearly the person speaks.
Session: Type the learners will undergo training in vocalics
Activity-2 Travel blogs / E-Travel Diary 6 hours
Briefing on the art of writing travel blogs.
Session: The learners will engage in writing relevant blogs
Reference Books
1. Githa Hariharan (2013) The Thousand Faces of Night, Royal New Zealand Foundation of the
Blind
2. O’ Brien, Terry, (2011) Effective English Skills, Nd: Rupa
3. Kumar, Sanjay & Puspalata, (2015-2nd Ed) Communication Skills,Nd: OUP
Mode of Evaluation: Quizzes, Presentation, Discussion, Role play, Assignments & FAT
List of Challenging Experiments (Indicative)
1 Interpreting short texts and writing a paragraph 8 hours
2 Writing an abstracts 10 hours
3 Mock Interviews through video conferencing 12 hours
Reference Books
1. Dhaliwal, K.K, “Gandhian Philosophy of Ethics: A Study of Relationship between his
Presupposition and Precepts,2016, Writers Choice, New Delhi, India.
2. Vittal, N, “Ending Corruption? - How to Clean up India?” 2012, Penguin Publishers, UK.
3. Pagliaro, L.A., and Pagliaro, A.M, “Handbook of Child and Adolescent Drug and
Substance Abuse: Pharmacological, Developmental and Clinical Considerations,”
4. 2012Wiley Publishers, U.S.A.
Pandey, P. K (2012), “Sexual Harassment and Law in India,” 2012, Lambert Publishers,
Germany.
Course Outcomes
At the end of the course, the student should be able to
[1] Solve a system of linear equations by matrix method
[2] Apply the techniques of differentiation to find maxima and minima, and techniques of
integration to evaluate areas and volumes of revolution
[3] Understand the concept of ordinary differential equations, and first and second-order linear
differential equations
[4] Have a clear understanding of analytic geometry and vector algebra
[5] Apply concepts of mathematical logic and elementary probability to real-life problems
• A minimum of 10 problems to be
worked out by students in every
Tutorial Class
• Another 5 problems per Tutorial Class
Tutorial 30 hours
to be given as homework
Reference Books
• Elementary Engineering Mathematics, B. S. Grewal, 43rd edition, Khanna Publications, (2015).
• Discrete Mathematics, Seymour Lipschutz and Marc Lipson, 6th Edition, Tata McGraw -Hill (2017).
• Introduction to Probability and Statistics, Seymour Lipschutz and John Schiller, 3rd Indian Edition,
Tata McGraw -Hill (2017).
Mode of Evaluation
Digital Assignments (Solutions by using a soft skill), Quiz, Continuous Assessments, Final
Assessment Test
Recommended by Board of Studies 25-02-2017
Approved by Academic Council No. 47 Date 05-10-2017
Expected Course Outcome: On the completion of this course, the student will be able to:
1. Understand developing business models and growth drivers
2. Use the business model canvas to map out key components of the enterprise
3. Analyze market size, cost structure, revenue streams, and value chain
4. Understand build-measure-learn principles
Foreseeing and quantifying business and financial risks
Module:1 2 Hours
Creativity and Design Thinking (identify the vertical for business opportunity, understand your
customers, accurately assess market opportunity)
Module:2 3 Hours
Minimum Viable Product (Value Proposition, Customer Segments, Build- measure-learn process)
Module:3 3 Hours
Business Model Development(Channels and Partners, Revenue Model and streams, Key
Resources, Activities and Costs, Customer Relationships and Customer Development Processes,
Business model canvas –the lean model- templates)
Module:4 3 Hours
Business Plan and Access to Funding(visioning your venture, taking the product/ service to
market, a Market plan including Digital & Viral Marketing, start-up finance - Costs/Profits &
Losses/cash flow, Angel/VC,/Bank Loans and Key elements of raising money)
Module:5 3 Hours
Legal, Regulatory, CSR, Standards, Taxes
Module:6 2 Hours
Lectures by Entrepreneurs
M.Sc Intg Biotechnology (5yr.) Page 45
Total Lecture 15 hours
Text Book(s)
1. The Startup Owner's Manual: The Step-By-Step Guide for Building a Great Company, Steve
Blank, K & S Ranch; 1st edition (March 1, 2012)
2
The Four Steps to the Epiphany, Steve Blank, K&S Ranch; 2nd edition (July 17, 2013)
3 The Lean Startup: How Today's Entrepreneurs Use Continuous Innovation to Create Radically
Successful Businesses, Eric Ries, Crown Business; (13 September 2011)
Reference Books
1. Holding a Cat by the Tail, Steve Blank, K&S Ranch Publishing LLC (August 14, 2014)
2 Product Design and Development, Karal T Ulrich, SD Eppinger, McGraw Hill
3 Zero to One: Notes on Startups, or How to Build the Future, Peter Thiel, Crown
Business(2014)
4 Lean Analytics: Use Data to Build a Better Startup Faster (Lean Series), Alistair Croll &
Benjamin Yoskovitz, O'Reilly Media; 1st Edition (March 21, 2013)
5 Inspired: How To Create Products Customers Love, Marty Cagan, SVPG Press; 1st edition
(June 18, 2008)
6 Website References:
1. http://theleanstartup.com/
2. https://www.kickstarter.com/projects/881308232/only-on-kickstarter-the-leaders-guide-
by-eric-ries
3. http://businessmodelgeneration.com/
4. https://www.leanstartupmachine.com/
5. https://www.youtube.com/watch?v=fEvKo90qBns
6. http://thenextweb.com/entrepreneur/2015/07/05/whats-wrong-with-the-lean-startup-
methodology/#gref
7. http://www.businessinsider.in/Whats-Lean-about-Lean-Startup/articleshow/53615661.cms
8. https://steveblank.com/tools-and-blogs-for-entrepreneurs/
9. https://hbr.org/2013/05/why-the-lean-start-up-changes-everything
10. chventures.blogspot.in/ platformsandnetworks.blogspot.in/p/saas-model.html
Mode of Evaluation: Assignments; Field Trips, Case Studies; e-learning; Learning through
research, TED Talks
Project
1. Project 60 hours
Total Project 60 hours
Recommended by Board of Studies 08-06-2015
Approved by Academic Council 37 Date 16-06-2015
Text Book(s)
1. Text Book:“Aula Internacional 1”, Jaime Corpas, Eva Garcia, Agustin Garmendia,
Carmen Soriano Goyal Publication ; reprinted Edition, (2010)
Reference Books
1 “¡AcciónGramática!”, Phil Turk and Mike Zollo, Hodder Murray, London 2006.
“Practice makes perfect: Spanish Vocabulary,” Dorothy Richmond, McGraw Hill
Contemporary, USA,2012.
2 “Practice makes perfect: Basic Spanish,” Dorothy Richmond, McGraw Hill Contemporary,
USA 2009.
3 “Pasaporte A1 Foundation”, Matilde Cerrolaza Aragón, Óscar Cerrolaza Gili, Begoña Llovet
Barquero, Edelsa Grupo, España, 2010.
Text Book(s)
Module:1 3 hours
Begrüssung, Landeskunde, Alphabet, Personalpronomen, Verben- heissen, kommen, wohnen,
lernen, Zahlen (1-100), W-Fragen, Aussagesätze, Nomen- Singular und Plural, der Artikel -
Bestimmter- Unbestimmter Artikel)
Lernziel :
Sich vorstellen, Grundlegendes Verständnis von Deutsch, Deutschland in Europa
Module:2 3 hours
Konjugation der Verben (regelmässig /unregelmässig),das Jahr- Monate, Jahreszeiten und die
Woche, Hobbys, Berufe, Artikel, Zahlen (Hundert bis eine Million), Ja-/Nein- Frage, Imperativ
mit ,,Sie’’
Lernziel:
Sätze schreiben, über Hobbys, Berufe erzählen, usw
Module:3 6 hours
Possessivpronomen, Negation, Kasus (Bestimmter- Unbestimmter Artikel) Trennbareverben,
Modalverben, Uhrzeit, Präpositionen, Lebensmittel, Getränkeund Essen, Farben, Tiere
Lernziel :
Sätze mit Modalverben, Verwendung von Artikel, Adjektiv beim Verb
Module:5 5 hours
Leserverständnis. Mindmap machen, Korrespondenz- Briefe und Email
Lernziel:
Übung der Sprache, Wortschatzbildung
Module:6 5 hours
Aufsätze :Die Familie, Bundesländer in Deutschland, Ein Fest in Deutschland,
Lernziel :
Aktiver, selbständiger Gebrauch der Sprache
Module:7 4 hours
Dialoge:
a) Gespräche mit einem/einer Freund /Freundin.
b) Gespräche beim Einkaufen ; in einem Supermarkt ; in einer Buchhandlung ;
c) in einem Hotel - an der Rezeption ; ein Termin beim Arzt.
d) Ein Telefongespräch ; Einladung–Abendessen
Module:8 2 hours
Guest Lectures/ Native Speakers ( Einleitung in die deustche Kultur und Politik
Total Lecture hours: 30 hours
Text Book(s)
1. Netzwerk Deutsch als Fremdsprache A1, Stefanie Dengler, Paul Rusch, Helen Schmtiz, Tanja
Sieber, Klett-Langenscheidt Verlag, München : 2013
Reference Books
1. Lagune, Hartmut Aufderstrasse, Jutta Müller, Thomas Storz, 2012.
2 Deutsche Sprachlehre für Ausländer, Heinz Griesbach, Dora Schulz, 2013
3 Studio d A1, Hermann Funk, Christina Kuhn, CorneslenVerlag, Berlin :2010
4 Tangram Aktuell-I, Maria-Rosa, SchoenherrTil, Max Hueber Verlag, Muenchen :2012
www.goethe.de
wirtschaftsdeutsch.de
hueber.de
klett-sprachen.de
www.deutschtraning.org
Mode of Evaluation: CAT / Assignment / Quiz / FAT
Recommended by Board of Studies DD-MM-YYYY
Approved by Academic Council No. xx Date DD-MM-YYYY
Text Book(s)
1. “Aula Internacional 1”, Jaime Corpas, Eva Garcia, Agustin Garmendia, Carmen Soriano
Goyal Publication; reprinted Edition, Delhi (2010)
Reference Books
1. “¡AcciónGramática!”, Phil Turk and Mike Zollo, Hodder Murray, London 2006.
2. “Practice makes perfect: Spanish Vocabulary”, Dorothy Richmond, McGraw Hill
Contemporary, USA,2012.
3. “Practice makes perfect: Basic Spanish”, Dorothy Richmond, McGraw Hill Contemporary,
USA 2009.
4. “Pasaporte A1 Foundation”, Matilde Cerrolaza Aragón, Óscar Cerrolaza Gili, Begoña Llovet
Barquero, Edelsa Grupo, España, 2010.
Authors, book title, year of publication, edition number, press, place
Recommended by Board of Studies DD-MM-YYYY
Approved by Academic Council No. xx Date DD-MM-YYYY
Course Objectives:
• To enhance critical thinking and innovative skills
• To have a working knowledge of communicating in English
• To have critical thinking and innovative skills
Transactional Analysis
Introduction, Contracting, Ego states, Life positions
Brain storming
Individual Brainstorming, Group Brainstorming, Stepladder Technique, Brain writing, Crawford's
Slip writing approach, Reverse brainstorming, Star bursting, Charlette procedure, Round robin
brainstorming
Psychometric Analysis
Skill Test, Personality Test
Rebus Puzzles/Problem Solving
More than one answer, Unique ways
Theatrix
Motion Picture, Drama, Role Play, Different kinds of expressions
Creative expression
Writing, Graphic Arts, Music, Art and Dance
Flexibility of thought
The 5'P' framework (Profiling, prioritizing, problem analysis, problem-solving, planning)
Adapt to changes(tolerance of change and uncertainty)
Adaptability Curve, Survivor syndrome
Text Book(s)
1. Chip Heath, How to Change Things When Change Is Hard (Hardcover), 2010, First Edition,
Crown Business.
Karen Hough, The Improvisation Edge: Secrets to Building Trust and Radical Collaboration
3. at Work, 2011, Berrett-Koehler Publishers
Reference Books
Mode of Evaluation: FAT, Assignments, Projects, Case studies, Roleplays,3 Assessments with
Term End FAT (Computer Based Test)
10 Tips to prepare PowerPoint presentation, Outlining the content, Passing the Elevator Test, Blue
sky thinking, Introduction, body and conclusion, Use of Font, Use of Color, Strategic presentation,
Importance and types of visual aids, Animation to captivate your audience, Design of posters,
Setting out the ground rules, Dealing with interruptions, Staying in control of the questions,
Handling difficult questions
Write a short, catchy headline, Get to the Point –summarize your subject in the first paragraph,
Body – Make it relevant to your audience
Module:4 Listening and speaking skills 10 hours
Debate, Idea generation, Research, Articulating, Style, Preparation of arguments –Rebuttal, Use of
statistics, Types of Listening, Hearing, Focus, Voice, Verbal and Non-verbal messages Practice
rounds, How to present a JAM, Public speaking.
Reference Books
1. Dale Carnegie,(1936) How to Win Friends and Influence People. New York City. Gallery
Books
2. Joyce Aemstrong and Carroll(1992) Integrated Teaching of Reading, Writing, Listening,
Speaking, Viewing and Thinking. Korea. Libraries Unlimited Inc.
3. Theo Theobald(2011) Develop your Presentation Skills. New Delhi. Kogan Page Limited.
Websites:
1. www.chalkstreet.com
2. www.skillsyouneed.com
3. www.mindtools.com
4. www.thebalance.com
Coding & decoding, Series, Analogy, Odd man out and Visual reasoning
• Coding and Decoding
• Series
• Analogy
• Odd Man Out
• Visual Reasoning
Sudoku puzzles
Attention to detail
Picture and word driven Qs to develop attention to detail as a skill
Mode of Evaluation: FAT, Assignments, 3 Assessments with Term End FAT (Computer Based
Test)
Text Book(s):
Mode of Evaluation: FAT, Assignments, 3 Assessments with Term End FAT (Computer Based Test)
Text Book(s):
5. FACE, Aptipedia Aptitude Encyclopedia, 2016, 1st Edition, Wiley Publications, Delhi.
6. ETHNUS, Aptimithra, 2013, 1st Edition, McGraw-Hill Education Pvt.Ltd.
7. SMART, PlaceMentor, 2018, 1st Edition, Oxford University Press.
8. R S Aggarwal, Quantitative Aptitude For Competitive Examinations, 2017, 3rd Edition, S.
Chand Publishing, Delhi.
Reference Book(s):
Arun Sharma, Quantitative Aptitude, 2016, 7th Edition, McGraw Hill Education Pvt. Ltd.
Mode of Evaluation: FAT, Assignments, 3 Assessments with Term End FAT (Computer
Based Test)
Text Book(s):
9. FACE, Aptipedia Aptitude Encyclopedia, 2016, 1st Edition, Wiley Publications, Delhi.
10. ETHNUS, Aptimithra, 2013, 1st Edition, McGraw-Hill Education Pvt.Ltd.
11. SMART, PlaceMentor, 2018, 1st Edition, Oxford University Press.
12. R S Aggarwal, Quantitative Aptitude For Competitive Examinations, 2017, 3rd Edition,
S. Chand Publishing, Delhi.
Reference Book(s):
Arun Sharma, Quantitative Aptitude, 2016, 7th Edition, McGraw Hill Education Pvt. Ltd.
Mode of Evaluation: FAT, Assignments, Mock interviews, 3 Assessments with Term End FAT
(Computer Based Test)
Text Book(s):
13. FACE, Aptipedia Aptitude Encyclopedia, 2016, 1st Edition, Wiley Publications, Delhi.
14. ETHNUS, Aptimithra, 2013, 1st Edition, McGraw-Hill Education Pvt.Ltd.
15. SMART, PlaceMentor, 2018, 1st Edition, Oxford University Press.
16. R S Aggarwal, Quantitative Aptitude For Competitive Examinations, 2017, 3rd Edition,
S. Chand Publishing, Delhi.
Reference Book(s):
Arun Sharma, Quantitative Aptitude, 2016, 7th Edition, McGraw Hill Education Pvt. Ltd.
Reference Books
1. Java The Complete Reference, 2014, 9th Edition by By Herbert Schildt, McGraw-Hill
Education Pvt Ltd
2. Introduction to Programming with Java: A Problem-Solving Approach
by John Dean
Mode of Evaluation: FAT, Assignments, 3 Assessments with Term End FAT (Computer Based
Test)
Printing
Getting input from the user during run time
Command-line arguments
Solving programming questions based on CLA
Reference Books
1. Java The Complete Reference, 2014, 9th Edition by By Herbert Schildt, McGraw-Hill
Education Pvt Ltd
2. Introduction to Programming with Java: A Problem-Solving Approach
by John Dean
Mode of Evaluation: FAT, Assignments, 3 Assessments with Term End FAT (Computer Based
Test)
Text Book(s)
1. Nelson DL and Cox MM (2012) Lehninger’s Principles of Biochemistry, Sixth Edition, WH
Freeman, New York.
Cell theory, diversity, and commonalty of cells and evolutionary relations between organisms.
Structure of prokaryotic and eukaryotic cells; plant and animal cells.
Biomembrane: lipid and protein constituents, cytoskeleton, cell wall, nucleus, mitochondria,
chloroplast, endoplasmic reticulum, Golgi apparatus, peroxisome, vacuole, lysosome, ribosome,
centrosome, and glyoxisome.
Cell division in prokaryotes and eukaryotes, mitosis and meiosis, and regulation of cell cycle
by mitogens, cyclins, and Cdks. Apoptosis in multicellular organisms.
Text Book(s)
1. Lodish H, Berk A Kaiser CA Krieger M, Bretscher A, Ploegh H, Amon A, Martin KC
(2012) Molecular Cell Biology, 7th edition, W.H. Freeman. USA.
Reference Books
1. Lynne B. Jorde, John C. Carey, Michael, J. Bamshad, and Raymond, L. White (2010)
Medical genetics. 4th edition, Mosby. USA.
2. Cooper GM and Hausman RE (2013) The Cell: A Molecular Approach. 6th edition. Sinauer
Associates, Inc. USA.
Text Book(s)
1. Krishnamurthy KV (2017) An advanced textbook on Biodiversity, Principle and Practice,
Oxford and IBH publishing Co. Pvt.
Frankham (2010), Jonathan D. Ballou, David A. Briscoe. Introduction to Conservation
2.
Genetics, 2nd edition, Cambridge.
3.
Richard BP (2016) Principles of Conservation Biology, 4th edition, Sinauer Associates, Inc.
Reference Books
1. Reddy GV, Karanth KU, Samba Kumar N, Krishnaswamy J and Karanth KK (2016)
Recovering biodiversity in Indian forests, Springer
Talent JA (2012) Earth and Life, Springer
Prokaryotic and eukaryotic chromosome structure, variations in structure and number. Giant
chromosomes - sex determination in plants and animals, dosage compensation. Sex chromosomes
and sex-linked inheritance, Extrachromosomal inheritance.
Module:3 Model systems to study genetics 4 hours
Hardy – Weinberg law and its applications, Factors affecting allele frequencies, selection,
mutation, migration and genetic drift, inbreeding and outbreeding, Quantitative Genetics, C-
value.
Module:5 Mutation 4 hours
Spontaneous and Induced mutations, and its role in evolution, Radiation injury and DNA repair
mechanisms, Relationship between Mutations and Phenotypes, genetic toxicity testing.
Module:6 Biochemical Genetics 4 hours
Text Book(s)
1. Snustad DP, Simmons MJ (2011) Principles of Genetics (6th Edition) John Wiley
publications
Bhaskar (2012) Textbook of genetics, Campus book international.
Reference Books
1. T A Brown (2011) Introduction to Genetics: A Molecular Approach Garland Science.
‘J’ component: Experiments
Mode of Evaluation: CAT / Assignment / Quiz / FAT / Project / Seminar
Recommended by Board of Studies 03-08-2017
Approved by Academic Council No. 46 Date 24-08-2017
Microscopes (light microscope, phase contrast microscope, dark ground microscope, fluorescent
microscope, and electron microscope). Staining methods and identification of Bacteria. Different
culture methods, techniques of pure culture and preservation of cultures
Module:3 Microbial Nutrition, transport and 4 hours
Growth
Text Book(s)
1. Tortora GJ, Funke BR, Case CL (2015) Microbiology: An Introduction / 12th Edition
2. Willey JM, Sherwood LM, and Woolverton CJ (2016) Prescott's Microbiology 10thedition
McGraw Hill
2. Tille PM (2016) Bailey & Scott's Diagnostic Microbiology, 14thEdition Mosby Elsevier
Project: ‘J’ component
Mode of Evaluation: CAT / Assignment / Quiz / FAT / Project / Seminar
List of Challenging Experiments (Indicative)
1. Different methods to sterilization 2 hours
2. Staining: Simple staining, differential staining, Capsule staining, Spore 4 hours
staining, acid-fast staining, and Lacto phenol cotton blue (LPCB).
3. Microbial specific media preparation: Solid and liquid media 2 hours
4. Techniques to culture microbes on solid media: Pour plate, Spread plate, 6 hours
Streak plate, and Dilution techniques.
5. Biochemical test for identification of bacteria: Catalase test, Oxidase test, 6 hours
Urease test, IMViC test, LAO test, Gelatin liquefaction test, Starch
degradation test, Carbohydrate fermentation.
6. Isolation of antibiotics producing microorganisms from soil 4 hours
7. Kirby-Bauer method of antibiotic susceptibility test 4 hours
8. Growth curve 2 hours
Total Laboratory Hours 30 hours
Mode of evaluation: CAT / Assignments / FAT / Quiz
Recommended by Board of Studies 03-08-2017
Approved by Academic Council No. 46 Date 24-08-2017
Introduction to human anatomy and physiology. Anatomical and medical terminology. Osteology,
joints, and muscle cells. Body fluids and homeostasis
Module:2 Blood and its components 6 hours
Composition and functions of blood. Plasma proteins. Red blood cells, White blood cells, and
platelets. Blood groups and blood clotting.
Module:3 Digestive and excretory system 7 hours
Organs of the digestive system. Salivary secretion, gastric secretion, and pancreatic secretion.
Bile secretion and functions of bile. Absorption of food substances. Movements of the
digestive tract. Structure and function of excretory organs such as kidney, skin, and liver.
Module:4 Endocrine and reproductive systems 7 hours
Organs of the respiratory system. Structure of the lungs. Mechanics of respiration. Lung volumes
and capacities. Transport of oxygen in the blood. Transport of carbon dioxide in the blood.
Regulation of respiration
Module:6 Cardiovascular system 6 hours
Structure of neuron. Resting membrane potential and action potential. Brain and spinal cord,
reflex action. Functions of the cerebral cortex, Basal ganglia, Thalamus, hypothalamus, and
cerebellum.
Module:8 Contemporary issues: Lectures form 2 hours
industry/Hospital
Text Book(s)
1. Ross JS, Wilson KJ, and Waugh A (2014) Ross and Wilson Anatomy and Physiology in
Health and Illness: Allison Grant: Books, 11th Edition, IRL press (Oxford University
Press, USA)
Reference Books
1. Richard S. Snell (2011) Clinical Anatomy 9th edition Lippincott Williams
2. Keele CA, Neil E, Joels N (2015) Samson Wright’s Applied Physiology, 13th edn Oxford
University Press, Hong Kong
Text Book(s)
1. Alberts B, Johnson A, Lewis J, Morgan D, Raff M, Roberts K, and Walter P (2014)
Molecular Biology of the Cell. 6th edition. Garland Science, USA.
2. Cooper G M and Hausman R E (2013) The Cell: A Molecular Approach. 6th edition. Sinauer
Associates, Inc. The USA.
Text Book(s)
1. Kothari C.R. (2013) Research Methodology – Methods and Techniques – 3rd edition.
New age international publishers. New Delhi
2. Kothari C.R. and Gaurav Garg (2019) Research Methodology: Methods and Techniques
Reference Books
1. Trochim W, Donnelly JP, Arora K 2015. Research Methods: the essential knowledge base.
Cengage Learning. USA
Types of the solution- molarity, percent solutions, buffers- Henderson hasselbach equation, types
of buffers. Preparation of buffers, pH meter.
Module:3 Advanced microscopy 6 hours
Principle, construction, and working of Bright-field, SEM, and TEM – image formation,
resolving power and magnification.
Module:4 Chromatography 6 hours
Principle and working of Gel Electrophoresis, Pulse field, Zone, Isoelectric focussing, Capillary,
Gel filtration, and Affinity.
Module:6 Spectrophotometry 6 hours
Text Book(s)
1. Rajan Katoch (2011) Analytical Techniques in Biochemistry and Molecular Biology
Springer Science & Business Media
2.
Wilson K and Walker J (2016) Principles and Techniques of Biochemistry and Molecular
Biology 8th Ed. Cambridge University Press.
Reference Books
1. Boyer RF (2012) Biochemistry Laboratory: Modern Theory and Techniques, Prentice-
Hall.
Overview of the immune system, innate immunity, acquired immunity, cells, and organs of the
immune system, antigens, structure of antigen, and its different types.
Module:2 Immune cells 6 hours
Biology of T and B lymphocytes, functions of T cells, and B cells. Antibodies, structure, types,
and their functions. TCR structure. Antibody structure and types. Molecular basis of TCR and
antibody diversity.
Module:3 Defense strategies in immune system 6 hours
Major Histocompatibility Complex, Class-I, II, and III, Antigen processing and presentation.
Transplantation immunology
Module:5 Immune related disorders 6 hours
Text Book(s)
1. Janis Kuby (2013), Immunology, 7th edition. W.H Freeman and company.
2. Abbas AK, Lichtman AH, and Pillai S (2012) Basic immunology: functions and disorders
of the immune system. 4th edition Elsevier health sciences.
Reference Books
1. Chapel H, Haeney M, Misbah S and Snowden N,(2014) Essentials of Clinical Immunology
6th Edition, Wiley Blackwell.
Text Book(s)
1. Bhatt B. I and Thakore S B. (2017) Stoichiometry, 5th edition, Tata McGraw Hill.
2. McCabe W, Smith J, and Harriott P, (2017) Unit operations of Chemical Engineering, 7th
Edn, McGraw Hill International Editions.
Reference Books
1. Himmelblau D.M. and Riggs JB (2015) Basic Principles and Calculations in Chemical
Engineering, 8th Edn, Pearson education India
2. White F.M. Fluid Mechanics in S I units, 2017, 8th Edition, McGraw Hill Inc.
Text Book(s)
1. Pevsner J (2015) Bioinformatics and functional genomics 3rd edition John Wiley, UK
2. Higgs PG and Attwood TK (2013) Bioinformatics and molecular evolution. John Wiley UK
Bioresource – Plant and Animal: Aquatic and terrestrial, Natural resources and human populations
Genetics resources, human resources – biosystematics, productivity, and working practices.
Module:2 Ecological Values, Economic value 4 hours
Species, habitats, and ecosystem, poverty, cultural values, ethics, and equity. Living plant
(produce) collections, botanical gardens, zoo and aquaria, marine stations.
Module:3 Biodiversity loss, causes of Biodiversity loss 4 hours
Biological Resources – rules, property rights, and intellectual resource rights; Fair and
Equitable benefits sharing. Legal measures – traditional, national, and international laws.
Biodiversity Act, 2002, and Biodiversity Rules 2004.
Module:4 Sustainable use of biodiversity 4 hours
Biodiversity information management -data collection, tools and techniques, Protected Area
Network (PAN), Measures for conservation and sustainable use of biodiversity in natural
resource management; Biodiversity and Biotechnology – sustainable use of bioresources.
Module:5 Socio-economic Dimensions of Environmental 4 hours
Management
Population explosion and social factors are affecting development. Impact of development on the
environment - changing patterns of land use, land reclamation, deforestation, resource depletion,
pollution, and environmental degradation.
Text Book(s)
1. umar D, Rajendran KV and Jahageerdar S (2011) Bioresource Management and Climate
Change Studium Press (India) Pvt. Ltd.
2. Raju NJ, Gossel W, Ramanathan AL, and Sudhakar M (2014) Management of water,
energy, and Bioresources in the era of climate change: emerging issues and challenges.
Springer.
Reference Books
1. Thangadurai D and Sangeetha J (2017) Industrial Biotechnology: Sustainable production and
Bioresource utilization, Apple Academic Press.
2. Etingoff K (2014) Agricultural resource use and management Apple academic press NJ.
Group Project Presentation: Case studies of different business models and IPR, eg. Biocon is
protecting cancer medicine.
Text Book(s)
1. Principles of gene manipulation and Genomics - Primrose S.B. and Twyman R.M.
Blackwell
Scientific Publications, 2008.
2. Genes IX - Benjamin Lewis. Oxford University & Cell Press, 2008.
3. Shahi, G. BioBusiness in Asia: How Asian Countries Can Capitalize on the
Life Science Revolution. Pearson Prentice Hall. 2004.
4. Hirsch RD & Peters MP, “Entrepreneurship,” Tata McGraw Hill Publishers, New Delhi,
2002.
5. Holt DH, “Entrepreneurship – New Venture Creation,” Prentice Hall of India, 1999.
Reference Books
Module content
Homologous Recombination, enzymes, and models (Double-stranded invasion model and
Meselson and Radding model). Site-specific recombination (Bacteriophage lambda). Short
sequence recombination
Module:6 Transposition 4 hours
Module content
Transposons, structure ,types and mechanism
Module:7 Bacteriophage and Natural Plasmids 6 hours
Module content
Text Book(s)
1. Chaudhuri K (2012) Microbial Genetics The Energy and Resources Institute, TERI
2. Snyder L, Peters JE, Henkin TM, Champness W (2013) Molecular Genetics of Bacteria,
4thEdition ASM press
Reference Books
1. Krebs JE Lewin B, Goldstein ES and Kilpatrick ST (2014) Lewin's GENES XI Jones &
Bartlett Publishers
Text Book(s)
1. Old RW and Primrose SB (2014) Principles of gene manipulation, 7th edn Wiley
Blackwell Scientific Publications.
2. Jogdand SN (2016) GENE biotechnology 4th Edn Himalaya publishing group
Reference Books
1. Somnath De (2016) Basic Concept of Recombinant DNA Technology Createspace
Independent Publications India
2. Sambrook and Russel. Molecular cloning Vol. 1-3, CSH Press (from 2001 till date updated
protocols)
Mode of Evaluation: CAT / Assignment / Quiz / FAT / Project / Seminar
List of Challenging Experiments (Indicative)
1. Preparation of competent cells (BL -21). 4 hours
2. Transformation of BL-21 competent cells with pGEX 4T-1 vector. 4 hours
3. IPTG induction of BL-21 cells containing pGEX 4T – 1 and isolation of 4 hours
proteins from control and induced cells.
4. Analysis of the protein profile of 3rd experiment on SDS-PAGE 4 hours
5. Purification of GST protein from whole cell lysate obtained from 3rd 4 hours
experiment
6. Cloning of the PCR product in TA cloning vector – transformation in DH5 a 4 hours
bacteria.
7. Screening for recombinant plasmid for experiment 6 by i) colony PCR ii) 4 hours
Restriction digestion.
Total Laboratory Hours 30 hours
Mode of evaluation: Assignments, Continuous assessment tests and Final assessment test.
Recommended by Board of Studies 03-08-2017
Approved by Academic Council No. 46 Date 24-08-2017
Text Book(s)
1. Stanbury P.F., Whitaker A, Hall S.J (2016) Principles of Fermentation Technology,
Butterworth Heinemann, 3rd edition. UK
2. Shuler M.L and Kargi F (2017) Bioprocess Engineering: Basic concepts Prentice Hall, 2nd
edition.
Reference Books
1. Doran PM (2013) Bioprocess Engineering Principles Elsevier, 2nd edition.
2. Cornish-Bowden A, (2012) Fundamentals of Enzyme Kinetics, Butterworth group, 4th
edition.
3. Okafor N (2016) Modern Industrial Microbiology and Biotechnology, SP publishers.
Mode of Evaluation: Assignments, Continuous assessment tests and Final assessment test.
Recommended by Board of Studies 03-08-2017
Approved by Academic Council No.46 Date 24-08-2017
Text Book(s)
1. S. C. Rastogi N. Mendiratta P. Rastogi (2013) Bioinformatics: Methods And Applications:
(Genomics, Proteomics And Drug Discovery), Edition 4, PHI Learning Pvt. Ltd
Reference Books
1. Schmidt D (2014) Using the Biological Literature: A Practical Guide, Fourth Edition by CRC
Press
Primrose SB, Twyman R (2013) Principles of Gene Manipulation and Genomics, 7th Edition:
2.
2013, Wiley-Blackwell
Mode of Evaluation: Assignments, Continuous assessment tests and Final assessment test.
Recommended by Board of Studies 03-08-2017
Approved by Academic Council No. 46 Date 24-08-2017
Text Book(s)
1. Lesk AM (2014) Introduction to Bioinformatics, 4th Edition, Oxford University Press UK
2. R.M. Twyman (2013) Principles of Proteomics, Taylor and Francis, Garland Science, UK
Reference Books
1. Mirzaei H and Carrasco M (2016) Modern Proteomics – sample preparation, analysis and
practical applications. Springer publications
Mode of Evaluation: Assignments, Continuous assessment tests and Final assessment test.
Recommended by Board of Studies 03-08-2017
Approved by Academic Council No.46 Date 24-08-2017
Text Book(s)
1. Wilson K and Walker J (2010) Principles and Techniques of Biochemistry and Molecular
Biology 7th Edn Cambridge University Press
2. Roe S (2010) Protein Purification Techniques: A Practical Approach 2nd edition Oxford
University Press
Reference Books
1. Belter PA, Cussler EL, and Hu WS (2011) Bioseparations: Downstream Processing for
Biotechnology Paperback Wiley
Mode of Evaluation: Written examinations, assignments, and quizzes.
List of Challenging Experiments (Indicative)
1. Protein estimation 2 Hours
2. Cell lysis followed by protein estimation 2 Hours
3. Precipitation of proteins (ammonium sulfate) 2 Hours
4. Precipitation of proteins (Acetone) 2 Hours
5. Aqueous two-phase extraction 2 Hours
6. Reverse micelle extraction 2 Hours
7. Size Exclusion Chromatography 2 Hours
8. Affinity chromatography 2 Hours
9. Dialysis 2 Hours
10 Crystallization 2 Hours
11 HPLC (Demonstration) 2 Hours
12 Fraction collector used in chromatography (Demonstration) 2 Hours
13 Lyophilization (Demonstration) 2 Hours
Total Laboratory Hours 30 hours
2. Khar RK and Vyas SP ( 2013) Lachman/Liebermans: The Theory and Practice of Industrial
Pharmacy, Publisher: CBS; 4th edition.
Text Book(s)
1. Peter F Stanbury, Allan Whitaker, Stephen J Hall, “Principles of Fermentation Technology”
Butterworth Heinemann, Third Edition,2016.
2. WulfCrueger, AnnelieseCrueger, K.R.Aneja, “ Biotechnology -A textbook of Industrial
Biotechnology” Medtech,2017
Reference Books
1. Colin Ratledge, Bjorn Kristiansen, “Basic Biotechnology” Cambridge University Press, Third
Edition,2006
2. Thangadurai D and Sangeetha J (2017) Industrial Biotechnology: Sustainable production and
Bioresource Utilization. CRC press
3. Michael L Shuler, FikretKargi, Mathew DeLisa (2017) Bioprocess Engineering, Third
Edition, Prentice-Hall International Series
Authors, book title, year of publication, edition number, press, place
Mode of Evaluation: CAT / Assignments / FAT
Project: ‘J’ component
Recommended by Board of Studies 03-08-2017
Approved by Academic Council No. 46 Date 24-08-2017
Optical techniques like UV-Vis and fluorescence spectroscopy; FTIR spectroscopy; electron
microscopy (TEM and SEM); Atomic Force Microscopy, dynamic light scattering, zeta potential
measurement, XRD (with emphasis on how these techniques to aid in characterizing
nanoparticles).
Routes of exposure; Fate of nanoparticles- short and long term; Cellular interaction;
environmental safety; Risk assessment and regulatory mechanisms.
Text Book(s)
1. Bhushan B (2010) Handbook of Nanotechnology, Springer-Verlag, Berlin,
Heidelberg,Germany
Reference Books
1. Xie Y (2012) The Nanobiotechnology Handbook CRC Press
2. Eddy G and Poinern J (2014) A Laboratory Course in Nanoscience and Nanotechnology by
CRC Press
Authors, book title, year of publication, edition number, press, place
Mode of Evaluation: CAT / Assignments / FAT
Recommended by Board of Studies 03-08-2017
Approved by Academic Council No. 46 Date 24-08-2017
Text Book(s)
1. John W, Morrow W, Sheikh NA, Schmidt CS and Davies DH (2012) Vaccinology: principles
and practice Wiley Blackwell
2. Karstak E (2010) Modern Vaccinology Springer US
Reference Books
1. Barrett A (2015) Vaccinology: an essential guide Wiley Blackwell
Mode of Evaluation: CAT / Assignments / FAT
Recommended by Board of Studies 03-08-2017
Approved by Academic Council No.46 Date 24-08-2017
Nutraceuticals for- cardiovascular health, HIV and cancer risk reduction, bone and joint health,
diabetes, hypertension, hypercholesterolemia, immune system, oxidative stress, cognitive
function, anti-aging, maternal and infant health, gut health, reproductive health.
Text Book(s)
1. Paul Insel , Don Ross, Kimberley McMahon, Melissa Bernstein 4rth edition. 2012.
Discovering Nutrition. Jones and Bartlett Publishers, Inc;
Reference Books
1. Catherine Sanderson and Mark Zelman. 2015. E s s e n t I a l H e a l t h, 1 s t E d I t I o n .G - W
publIshers
Mode of Evaluation: CAT / AssignmentS / FAT /
Recommended by Board of Studies 03-08-2017
Approved by Academic Council No. 46 Date 24-08-2017
Text Book(s)
1. Criminalistics: An Introduction to Forensic Science, 11/E, Richard Saferstein, ISBN-
10:0133458822 • ISBN-13: 9780133458824, 2015 • Prentice Hall.
Reference Books
1. Forensic DNA Typing, 2nd Edition, Biology, Technology, and Genetics of STR Markers, J
Butler, 2005, Imprint: Academic Press, eBook ISBN: 9780080470610, Print Book ISBN:
9780121479527, Pages: 688
3. Hendry Lee’s Crime Scene Handbook, H.C. Lee, T. Palmbach, M.T. Miller (Academic
Press), Published: June 2001, ISBN: 978-0-12-440830-2
Mode of Evaluation: Assignments, Continuous assessment tests and Final assessment test.
Text Book(s)
1. Nelson P (2013) Biological Physics with New Art. First edition, MacMillan Higher
Education.
Reference Books
1. Buxbaum E (2011) Biophysical Chemistry of Proteins: An Introduction to Laboratory
Methods, Springer
Text Book(s)
1. Singh SP (2015) Textbook of Biochemistry, Sixth Edition, CBS Publishers.
2. Lapsley M W, Day A and Ayling R (2014) Clinical Biochemistry: Metabolic and Clinical
Aspects. Churchill Livingstone, UK
Reference Books
1. Berg JM, Tymoczko JL, Gatto GJ, Jr Stryer L (2015) Biochemistry, Eighth Edition,
Macmillan learning.
Text Book(s)
1. Gilbert S F (2016) Developmental Biology, Illustrated edition, Sinauer Associates.
Reference Books
1. Hillis S and Berenbaum H (2014) LIFE: The Science of Biology, Tenth Edition. Sinauer
Associates Inc
Mode of Evaluation: Assignments, Continuous assessment tests and Final assessment test.
Text Book(s)
1. Attwood TK and Parry-Smith DJ (2014) Introduction to bioinformatics, Pearson
Education.
Reference Books
1. Mount D (2014) Bioinformatics: Sequence and Genome Analysis, Cold Spring Harbor
Laboratory Press, New York.
2. Most of the topics will be covered using online resources
Mode of Evaluation: CAT / Assignment / Quiz / FAT / Project / Seminar
List of Challenging Experiments (Indicative)
1. Conversion of sequence from one database format to another using file 3 hours
format converter
2. Extraction of real matrices and identification of promoter motifs by 3 hours
TRANSFAC
3. Identification of protein domains using Pfam 3 hours
4. MMDB- Molecular Modeling Database 3 hours
5. Evaluation of comparative protein structure models by Mod Base 2 hours
6. Comparing genes and genomes with Ensembl 2 hours
7. Variation data in Ensembl 2 hours
8. Finding features that regulate genes – the Ensembl Regulatory Build 2 hours
9. Determining Protein Physico-Chemical Properties using PDBsum 2 hours
10 Analysis of inherited and complex disease using HGMD 2 hours
11 Understanding high-level functions and utilities of the biological 2 hours
systemKyotoEncyclopedia of Genes and Genomes
12 Reactions took from KEGG ENZYME and additional reactions taken from 2 hours
the metabolic pathway maps in KEGG PATHWAY using KEGG
REACTION
13 Visualization of protein-protein interaction using STRING 2 hours
Total Laboratory Hours 30 hours
Mode of evaluation: Assignments, Continuous assessment tests and Final assessment test.
Recommended by Board of Studies 03-08-2017
Approved by Academic Council No. 46 Date 24-08-2017
Text Book(s)
1. Adrian Slater, N W Scott, M Fowler, Plant Biotechnology: The Genetic Manipulation of
Plants, Second Edition, 2014, Oxford University Press.
2. M.K. Razdan. 2014. Introduction to Plant Tissue Culture. 2nd Edition, Oxford and IBH
Publishing Company, India.
Reference Books
1. Wang, Aiming, and Ma, Shengwu. 2014. Molecular Farming in Plants: Recent Advances and
Future Prospects. Springer, New York, USA.
2. Gamborg OL and Phillips GC. 2013. Plant Cell, Tissue, and Organ Culture: Fundamental
Methods. Springer-Verlag.
Mode of Evaluation: CAT / Assignment / Quiz / FAT / Project / Seminar
List of Challenging Experiments (Indicative)
1. Media preparation for plant cell culture 4 Hours
2. Preparation of media for bacterial culture 4 Hours
3. Sterilization techniques 2 Hours
4. Instruments required for plant cell culture 2 Hours
5. Explant isolation methods 2 Hours
6. Different methods of sterilization for explants 2 Hours
7. Callus induction 2 Hours
8. Co-culturing of Agrobacterium containing an engineered plasmid 2 Hours
9. Agrobacterium-mediated transformation 2 Hours
10 Screening of transformed plant cells with the help of a marker assay 2 Hours
11 Protoplast isolation and fusion techniques 2 Hours
12 Shoot induction 2 Hours
13 Root induction and Hardening 2 Hours
Total Laboratory Hours 30 hours
Project ‘J’ Component
Mode of evaluation: Assignments, Quiz, Continuous assessment tests and Final assessment test
Recommended by Board of Studies 03-08-2017
Approved by Academic Council No. 46 Date 24-08-2017
2. Nelson, D.L., and Cox MM. (2012) Lehninger’s Principles of Biochemistry, Sixth Edition,
WH Freeman, New York.
Reference Books
1. Shanmugam S, Sathishkumar T, and Shanmugaprakash M (2012) Enzyme technology 2nd
edition IK international publishing House Pvt. Ltd
Text Book(s)
1. Bolander FF (2010) Molecular Endocrinology, 3rd edn Elsevier Academic Press
Reference Books
1. Park-Sarge OK and Curry Jr TE (2010) Molecular Endocrinology: Methods and protocols
springer protocols
2. .Leonard F (2010) Molecular Biology of steroid and nuclear hormone receptors Birkhauser
Mode of Evaluation: Written examinations, Projects, and assignments
Recommended by Board of Studies 03-08-2017
Approved by Academic Council No.46 Date 24-08-2017
Text Book(s)
1. Lucas JS, and Paul C. (2012) Aquaculture: Farming aquatic animals and plants.
Southgate, eds. John Wiley & Sons.
Reference Books
1. Dunham, RA (2011) Aquaculture and fisheries biotechnology: genetic approaches. CABI,
Manual of Diagnostic Tests for Aquatic Animals, 7th edition 2015 Renouf Publishing
2.
Company Limited
Mode of Evaluation: Assignments, Continuous assessment tests and Final assessment test.
Recommended by Board of Studies 03-08-2017
Approved by Academic Council No.46 Date 24-08-2017
Text Book(s)
1. Atkins P and de Paula J Atkins' Physical Chemistry, 10th edition, (2014).Oxford University
Press, UK.
Reference Books
1. Marques M.P., de Carvalho B, L.A.E., Haris, P.I (2013) Spectroscopy of Biological
Molecules IOS Press, Netherlands.
Text Book(s)
1. Cherian E (2011) Stem cells JP brothers medical publishers
Reference Books
1. Atala A (2012) Progenitor and Stem Cell Technologies and Therapies Woodhead publishing
2. Phinney DG (2011) Adult stem cells: Biology and methods of analysis Humana press
Mode of Evaluation: Assignments, Continuous assessment tests and Final assessment test.
Recommended by Board of Studies 03-08-2017
Approved by Academic Council No. 46 Date 24-08-2017
Text Book(s)
1. Purves D, Augustine GJ, Fitzpatrick D, Hall WC, LaMantia AS, and White LE
(2012)Neuroscience.Sinauerpublications Fifth Edition.
2. Zupanc, G. K. H. (2010) Behavioral Neurobiology: An Integrative Approach, Oxford
University Press. 2nd edition
Reference Books
1. Ropper AH, Samuels MA, and Klein JP (2014) Adams and Victor’s principle of neurology
McGraw Hill Education 10 Edn
Mode of Evaluation: Assignments, Continuous assessment tests and Final assessment test.
Recommended by Board of Studies 03-08-2017
Approved by Academic Council No. 46 Date 24-08-2017
Text Book(s)
1. Thankur IS (2011) Environmental biotechnology: Basic concepts and applications. Second
Edition (revised), I.K. International.
Reference Books
1. Maier RM, Pepper IL, Gerba CP (2011) Environmental Microbiology, Second Edition,
Academic Press.
Text Book(s)
1. Bromham L (2016) An Introduction to Molecular Evolution and Phylogenetics 2nd Edn
oxford
University press
Graur D and Li WH (2010) Fundamentals of Molecular Evolution,., three eds. Sinauer
2. Associates,
Reference Books
1. Pevsner J (2015) Bioinformatics and Functional Genomics, 3rd Edition Wiley-Blackwell.
Page R, and Holmes EC (2010) Molecular evolution, A phylogenetic approach, Blackwell
2. Science Inc;
Text Book(s)
1. Hayes AW, Kruger CL(2014) Haye’sPrinciples and Methods of Toxicology, Sixth Edition,
CRC Press.
Reference Books
1. Kilbey BJ, Legator M, Nichols W, and Ramel C (2012) Handbook of Mutagenicity test
procedures, Elsevier, Amsterdam.
2. Scott Hawley.R, Michelle Walker 2003 Advanced Genetic Analysis Finding Meaning in a
Genome, Wiley-Blackwell Publishing.
3.
Philip Meneely 2009 Advanced Genetic Analysis: Genes, Genomes, and Networks in
Eukaryotes 1st Edition, Oxford University Press.
Mode of Evaluation: Assignments, Continuous assessment tests and Final assessment test.
Text Book(s)
1. Cleland JL and Craik CS (2010) Protein Engineering: Principles and Practice, Wiley
publishers
2. Ramya M and Ponmurugan P (2015) Protein Engineering Narosa publishing house
Reference Books
1. Park S and Cochran J (2010) Protein Engineering and Design CRC Press
.
2. Creighton TE (2010) Protein Function – A Practical Approach (2nd ed.,), Oxford University
Press, Oxford, UK
Authors, book title, year of publication, edition number, press, place
Projects: ‘J’ Components
Mode of Evaluation: Assignments, Continuous assessment tests and Final assessment test.
Recommended by Board of Studies 03-08-2017
Approved by Academic Council No. 46 Date 24-08-2017
Text Book(s)
1. Leach AR (2010) Molecular Modeling, Principles & Applications, (Dorling Kindersley(India)
(P)Ltd with Pearson education Ltd, UK.
2. Arjun S (2103) Drug Discovery, Design & Development Lambert Academic publishing.
Reference Books
1. Clark T, Thurston DE, and Banting L (2012) Drug Design Strategies: Computational
Techniques& Applications Royal society of chemistry
Authors, book title, year of publication, edition number, press, place
Mode of Evaluation: Assignments, Continuous assessment tests and Final assessment test.
List of Challenging Experiments (Indicative)
1. Exploration of small molecule and macromolecule database 3 hours
2. Small molecule drawing and optimization using Chem Sketch 2 hours
3. Macromolecular visualization using PyMOL 3 hours
4. Macromolecular visualization using SPDBV 2 hours
5. Homology modeling of the drug target protein 2 hours
6. Protein structure exploration with active site prediction 2 hours
7. Protein-Protein interaction using HADDOCK 2 hours
8. Protein-Ligand interaction using Autodock 3 hours
9. Quantitative structure-activity relationships modeling tools 3 hours
10. Molecular Mechanics for small molecules 2 hours
11. Avogadro for molecular mechanics 2 hours
12. Pharmacophore screening of small molecules 2 hours
13. Quantitative structure-activity relationship 2 hours
Total Laboratory Hours 30 hours
Recommended by Board of Studies 03-08-2017
Approved by Academic Council No. 46 Date 24-08-2017
M.Sc Intg Biotechnology (5yr.) Page 186
Course code Course title L T P J C
BIY4001 Cancer Biology 3 0 0 0 3
Pre-requisite None Syllabus version
v. 1
Course Objectives:
1. Illustrate the cellular and molecular mechanisms that are dysregulated in cancerous cells.
2. Summarize the genomic technologies and develop critical thinking skills in cancer research
3. Analyze traditional chemotherapy and novel targeted therapeutic approaches
Cell cycle and molecular players involved in the cell cycle. Deregulation of cell cycle and causes
for deregulation of cell cycle. Role of an oncogene, proto-oncogene, tumor suppressor proteins,
and oncoviruses in cancer. Cancer and its types. Molecular mechanisms of mutagens such as
Chemical carcinogen and radiation. Types of carcinogen and their mode of action with an example.
Module 2 Evading apoptosis in cancer 6 hours
The apoptotic mechanism, altered pathways in cancer cells that can evade apoptosis. Pathways are
regulating tumor initiation and/or its progression.
Text Book(s)
1. . The Biology of Cancer – Robert Weinberg. Edition – 2nd ISBN:9780815342205 - 2013
Reference Books
1. Textbook readings; primary literature; in-class discussion. The Molecular Biology of
Cancer: A Bridge from Bench to Bedside. Stella Pelengaris, Mike Khan -2nd Edition - 2013
2. Molecular Biology of Cancer. Lauren Pecorina, 4th edition. Oxford University Press – 2016.
Mode of Evaluation: Assignments, Continuous assessment tests and Final assessment test.
Recommended by Board of Studies 03-08-2017
Approved by Academic Council No.46 Date 24-08-2017
Text Book(s)
1. Ward JD(2013) Principles of food science, 3rd edition. G-W Publishers
2. Jay JM, Loessner MJ, and Golden DA (2012) Modern food microbiology. Fifth Edition, An
Aspen Publication.
Reference Books
1. Jeantet R, Croguennec T, Schuck P, and Brule G (2016) Handbook of Food Science and
Technology 3: Food Biochemistry and Technology. Wiley and Sons Publishers.
Text Book(s)
1. Singh B, Gautam SK, and Chauhan M S (2015) Textbook of Animal Biotechnology, TERI.
New Delhi
2. Panno J(2014) Animal Cloning: The Science of Nuclear Transfer.
Reference Books
1. Freshney RI (2010) Culture of Animal Cells: A Manual of Basic Technique and Specialized
applications John Wiley & Sons, Inc.
Gene therapy for severe combined immune deficiencies, X-SCID and ADA-SCID; Gene therapy
for cystic fibrosis; Gene therapy for muscular dystrophies; Gene therapy for hemophilia A and B
Gene therapy for cancer; Gene therapy for neurodegenerative disorders, Alzheimer’s and
Parkinson’s diseases; Gene therapy for eye diseases, retinitis pigmentosa, and Leber’s
congenital amaurosis; Gene therapy for HIV infection
Text Book(s)
1. Giacca M (2010) Gene Therapy First Edition, Springer Press, USA
2. Elsersawel A (2016) Gene Editing, Epigenetic, Cloning, and Therapy. Author house
publishing
Reference Books
1. Herzog RW and Zolotukhin S (2010) A Guide to Human Gene Therapy (First Edition)
World Scientific Publishing Co, UK
2. Daniel S (2013) Advanced Textbook On Gene Transfer, Gene Therapy And Genetic
Pharmacology: Principles, Delivery And Pharmacological And Biomedical Applications Of
Nucleotide-based Therapies(Volume 1 of Icp Textbooks In Biomolecular Sciences) World
Scientific publishers, Singapore
3. Jayandharan GR (2018)Gene and Cell Therapy: Biology and Applications (First Edition)
Springer Nature, Singapore
Mode of Evaluation: Assignments, Continuous assessment tests and Final assessment test.
Text Book(s)
1. Khan MY and Khan F (2015) Principles of Enzyme `Technology PHI learning India
Text Book(s)
1. Joshi VK, Singh RS (2013) Food Biotechnology: Principles and Practices.
I K International Publishing House Pvt. Ltd; First Edition.
Reference Books
1. Lee BH (2014) Fundamentals of Food Biotechnology, 2nd Edition.John Wiley & Sons.
2. Pometto A, Shetty K, Paliyath G, and Levin RE (2005) Food Biotechnology. Second edition.
CRC Press.
Authors, book title, year of publication, edition number, press, place
Mode of Evaluation: Assignments, Continuous assessment tests and Final assessment test.
Project: ‘J’ Component
Text Book(s)
1. Ansari AA, Gill SS, Gill R, Lanza G, Newman L (2017) Phytoremediation Management of
Environmental Contaminants. Springer international publication
Text Book(s)
1. Amanullah M (2012) Medical Biochemistry and Biotechnology LAP Lambert Academic
Publishing
Orlicki R, Cieńciala C, Krylova LP, Pielichowski J, and Zaikov GE (2013) Pharmaceutical
2.
and Medical Biotechnology: New Perspectives Nova publishers UK Ed.
Reference Books
1. Wilson BA, Salyers AA (2011) Bacterial Pathogenesis: A molecular approach ASM Press,
3rd edition.
Delves PJ, Martin SJ, Burton DR, Roitt IM (2011) Roitt's Essential Immunology Wiley-
2.
Blackwell 12th Edition
Authors, book title, year of publication, edition number, press, place
Mode of Evaluation: Assignments, Continuous assessment tests and Final assessment test.