HESI Dosage Calculation Practice Exam
HESI Dosage Calculation Practice Exam
HESI Dosage Calculation Practice Exam
1. A client with cardiogenic shock weighs 220 lb and is receiving dopamine at the rate of 3
mcg/kg/minute. The solution strength available is dopamine 400 mg in 250 ml of D5W.
The nurse should set the infusion pump to deliver how many ml/hour? (Enter numeric
value only. If rounding is required, round to the nearest tenth.)
4. A client is receiving an IV solution of sodium chloride 0.9% (Normal Saline) 250 ml with
amiodarone (Cordarone) 1 gram at 17 ml/hour. How many mg/minute of amiodarone is
infusing? (Enter numeric value only. If rounding is required, round to the nearest tenth.)
5. A client who weighs 176 pounds is receiving an IV infusion with esmolol hydrochloride
(Brevibloc) at 48 ml/hour. The IV solution is labeled with the concentration of Brevibloc
10 mg/ml. How many mcg/kg/minute is the client receiving? (Enter numeric value only.)
6. The nurse is preparing the change-of-shift report for a client who has a 265 ml secondary
infusion that was started 2 hours ago at a rate of 85 ml/hour via an infusion pump. The
nurse should report that how many ml remain to be infused by the on-coming nurse?
(Enter numeric value only.)
11. The nurse is administering a 250 milliliter (ml) intravenous solution to be infused over 2
hours. How many ml/hour should the nurse program the infusion pump? (Enter numeric
value only.)
12. The nurse is preparing to administer 0.25 mg of bumetanide (Bumex) IV. The medication
is available in a vial labeled 1 mg/4 ml. How many ml of medication should the nurse
administer? (Enter numeric value only.)
13. A client with hypertension receives a prescription for carteolol (Cartel) 7.5 mg PO daily.
The drug is available in 2.5 mg tablets. How many tablets should the nurse administer?
(Enter numeric value only.)
16. The healthcare provider prescribes acetazolamide (Diamox) 600 mg/m2/day divided into
3 doses. The nurse calculates the child's body surface area (BSA) as 0.7 m2. How many
mg should the child receive per dose? (Enter numeric value only.)
18. A child who weighs 55 pounds receives a prescription for atovaquone with proguanil
(Malarone Pediatric) 125 mg/50 mg PO daily. A drug reference states that children 11 to
20 kg should receive 1 pediatric tablet daily; 21 to 30 kg should receive 2 pediatric tablets
daily; 31 to 40 kg should receive 3 pediatric tablets daily; and greater than 40 kg should
receive 1 adult tablet daily with food. The drug is available as atovaquone 62.5
mg/proguanil 25 mg pediatric tablets. How many tablets should the nurse administer?
19. A client receives a prescription for azithromycin (Zithromax) 500 mg PO x 3 days.
Azithromycin is available as 250 mg scored tablets. How many tablets should the nurse
administer per dose? (Enter numeric value only.
20. A child who is scheduled for a kidney transplant receives a prescription for basiliximab
(Simulect) 20 mg IV 2 hours prior to surgery. The medication is available in a 20 mg vial
that is reconstituted by adding 5 ml sterile water for injection, and administered in a 50
ml bag of normal saline over 30 minutes. The nurse should program the infusion pump to
deliver how many ml/hour? (Enter numeric value only.
21. A client with a gastrostomy tube (GT) receives a prescription for Osmolite® 1/2 strength
enteral formula at 80 ml/hour. To prepare a 4 hour solution, the nurse should dilute the
full-strength formula with how many ml of water? (Enter numeric value only.)
22. The nurse notes that a client is receiving an oxytocin (Pitocin) infusion via a pump that is
programmed to deliver 30 ml/hour. The available solution is Ringer's Lactated 1,000 ml
with Pitocin 20 units. How many milliunits/minute is the client receiving? (Enter numeric
value only.)
23. A client is receiving Heparin Sodium 25,000 Units in 5% Dextrose Injection 500 ml IV at
1,000 unit/hour per protocol for acute coronary syndrome (ACS). The client's partial
thromboplastin time (PTT) is 76 seconds. Based on the ACS protocol, the infusion should
be decreased by 100 units/hour for a PTT between 71 to 80 seconds. The nurse should
program the pump to deliver how many ml/hour? (Enter numeric value only.)
24. The healthcare provider prescribes oxytocin (Pitocin) 0.5 milliunits/minute for a client in
labor. One liter Ringer's Lactate with 10 units of oxytocin (Pitocin) is infusing. The nurse
should program the infusion pump at how many ml/hour? (Enter numeric value only.)
25. Docusate sodium (Colace) 0.3 grams is prescribed for a client who has frequent
constipation. Each capsule contains 100 mg. How many capsules should the nurse
administer?
26. A client who has a sinus infection is receiving a prescription for amoxicillin/clavulanate
potassium (Augmentin) 500 mg PO q8 hours. The available form is 250 mg
amoxicillin/125mg clavulanate tablets. How many tablets should the nurse administer for
each dose? (Enter numeric value only.)
27. The healthcare provider prescribes acetaminophen elixir (Tylenol elixir) 600 mg PO q6
hours for an adult client experiencing pain associated with maxillofacial surgery. The
bottle is labeled 500 mg/15 ml. How many ml should the nurse administer? (Enter
numeric value only. If rounding is required, round to the nearest tenth.)
28. A client who has AIDS is receiving octreotide (Sandostatin) 1,200 mcg by subcutaneous
injection every day for symptoms of diarrhea. Octreotide is available for injection in 1
mg/ml vials. How many ml should the nurse administer? (Enter numeric value only. If
rounding is required, round to the nearest tenth.)
29. A client is receiving dantrolene sodium (Dantrium) PO for malignant hyperthermia. The
maximum safe dose is 8 mg/kg/day in 4 divided doses. The client currently weighs 48.5
kg. What is the maximum safe dose the nurse should administer? (Enter numeric value
only. If rounding is required, round to the nearest whole number.)
30. A child with a urinary tract infection is receiving Cephalexin (Keflex) 100 mg suspension
PO QID. Keflex oral suspension is labeled 125 mg in 5 ml. How many ml should the
nurse administer? (Enter numeric value only. If rounding is required, round to the nearest
tenth.)
31. The healthcare provider prescribes a continuous intravenous infusion of dextrose 5% and
0.45% sodium chloride with KCl 20 mEq/1000 ml to be delivered over 8 hours. The
nurse should program the infusion pump to deliver how many ml/hour? (Enter numeric
value only. If rounding is required, round to the nearest whole number.)
32. A client receives a prescription for an intravenous infusion 0.45% sodium chloride 500
ml to be infused over 6 hours. The nurse should program the infusion pump to deliver
how many ml/hour? (Enter numeric value only. If rounding is required, round to the
nearest whole number.)
33. A client returns to the nursing unit from surgery with a prescription for Lactated Ringer's
solution 1,000 ml to be infused over 10 hours. The IV administration set delivers 60
gtts/ml. The nurse should regulate the infusion to deliver how many gtts/minute?
34. An IV infusion of dextrose 5% in normal saline with oxytocin (Pitocin) 20 units in 1,000
ml is prescribed for a client to control postpartum bleeding. The solution is to be
administered at a rate of 2 mu/minute. The nurse should program the infusion pump to
administer how many ml/hour? (Enter numeric value only. If rounding is required, round
to the nearest whole number.)
36. A client who has a gastrostomy feeding tube is receiving 3/4 strength Ensure 240 ml
every 6 hours. Full strength Ensure is available in a 240 ml can. The nurse should use
how many ml of Ensure to prepare the feeding? (Enter numeric value only. If needed,
round to the nearest whole number.)
37. 0.9% normal saline with inamrinone (Inocor) 0.1 grams/100 ml is prescribed for a client
with heart failure. The medication is to be delivered at a rate of 400 mcg/minute. The
nurse should program the infusion pump to deliver how many ml/hour? (Enter numeric
value only. If rounding is required, round to the nearest whole number.)
39. A client with septic shock receives a prescription for dextrose 5% in water with dopamine
(Intropin) 0.6 grams/250 ml at a rate of 5 mcg/kg/minute. The client's weight is 148 lbs.
The nurse should set the infusion pump to deliver how many ml/hour? (Enter numeric
value only. If rounding is required, round to the nearest whole number.)
40. A client with type 2 diabetes is receiving metformin (Glucophage) 1 gram PO twice daily.
The medication is available in 500 mg tablets. How many tablets should the nurse
administer? (Enter numeric value only.)
42. A client with pericardial effusion has phrenic nerve compression resulting in recurrent
hiccups. The healthcare provider prescribes metoclopramide (Reglan) liquid 10 mg PO q
6 hours. Reglan is available as 5 mg/5 ml. A measuring device marked in teaspoons is
being used. How many teaspoons should the nurse administer?
43. A client is receiving alprazolam (Xanax) 0.75 mg PO BID for anxiety. Alprazolam is
available in 0.5 mg scored tablets. How many tablets should the nurse administer? (Enter
numeric value only.)
44. A client with multiple sclerosis is prescribed Dantrolene (Dantrium) 0.1 grams PO BID
for spasticity. Dantrolene is available in 100 mg capsules. How many capsules should the
nurse administer? (Enter numeric value only.)
45. A client has a prescription for inamrinone (Inocor) 0.75 mg/kg IV bolus to be delivered
over 3 minutes. The client weighs 80 kg. Inamrinone is available for injection 100 mg/20
ml. How many ml of inamrinone should the nurse administer? (Enter numeric value only.
If rounding is required, round to the nearest tenth.)
46. A client who had mitral valve replacement surgery receives a prescription for dextrose
5% in water with 0.5 grams of dobutamine in 250 ml for IV infusion at a rate of 5
mcg/kg/minute. The client weighs 75 kg. The nurse should program the infusion pump to
deliver how many ml/hr? (Enter numeric value only. If rounding is required, round to the
nearest tenth.)
47. A healthcare provider prescribes a continuous infusion of 0.9% sodium chloride with
pancuronium (Pavulon) 25 mg/250 ml at a rate of 0.1 mg/kg/hr for a client with coronary
artery bypass grafting. The client weighs 78 kg. The nurse should program the infusion
pump to deliver how many ml/hour? (Enter numeric value only. If rounding is required,
round to the nearest tenth.
48. A client scheduled for surgery is to receive an IV infusion of 0.9% sodium chloride with
prochlorperazine edisylate (Compazine) 10 mg/50 ml over 30 minutes. The nurse should
program the infusion pump to deliver how many ml/hour? (Enter numeric value only.)
49. The healthcare provider prescribes an IV infusion of 0.9% sodium chloride with 40 mEq
KCl/500 ml to infuse over 3 hours for a client with hypokalemia. The nurse should
program the infusion pump to deliver how many ml/hour? (Enter numeric value only. If
rounding is required, round to the nearest whole number.)
Answer Key
1. Answer: 11.3
Rationale: First, convert pounds to kg, 220 lb : X = 2.2 lb : 1 kg = 100 kg. Next,
calculate the dosage per minute, 3 mcg/kg/min x 100 kg = 300 mcg/min. Convert
mcg/min to mcg/hour, 300 mcg/min x 60 min=18,000 mcg/hour. Convert mcg/hr to
mg/hour, 18,000 mcg/hr = 18.0 mg/hour. Calculate the rate, 400 mg : 250 ml = 18 mg : X
ml 400X = 4500 X = 11.25 = 11.3 ml. So, 18 mg/11.3 ml should be infused at 11.3
ml/hour.
2. Answer: 3.5
3. Answer: 1.9
Rationale: To change ml/hour to mcg/kg/minute, use the formula: desired rate (5
ml/hour) / volume available (500 ml) x dose available (800 mg) = 8 mg/hour. Next,
convert milligrams/hour to mcg/kg/minute: mg (8) x 1000 / kg (70) / 60 minutes = 1.904
= 1.9 mcg/kg/minute.Convert grams to mg, 1 gram equals 1,000 mg. Using ratio and
proportion - 1,000 mg : 250 ml :: X mg : 1ml 250X= 1,000 so X = 4 mg/ml is the solution
concentration of amiodarone. The infusion rate (ml/hour) x concentration (mg/ml)
divided by 60 minutes/hour 17 ml/hour x 4 mg/ml = 68/60 = 1.13 = 1.1 mg/minute.
4. Answer: 1.1
Rationale: Convert grams to mg, 1 gram equals 1,000 mg. Using ratio and proportion -
1,000 mg : 250 ml :: X mg : 1ml 250X= 1,000 so X = 4 mg/ml is the solution
concentration of amiodarone. The infusion rate (ml/hour) x concentration (mg/ml)
divided by 60 minutes/hour 17 ml/hour x 4 mg/ml = 68/60 = 1.13 = 1.1 mg/minute.
5. Answer: 100
Rationale: Convert pounds to kg by dividing 176 pounds by 2.2 pounds = 80 kg. Convert
the IV concentration from mg to mcg. 1 mg : 1000 mcg :: 10 mg : 10,000 mcg. Infusion
rate (48 ml/hour) x concentration (10,000 mcg/ml) divided by 60 minutes/hour x 80 kg =
48 x 10,000 divided by 60 x 80 = 480,000 / 4800 = 100 mcg/kg/minute.
6. Answer: 95
Rationale: 85 ml x 2 hours = 170 ml has infused. 265 ml (total amount to be infused) -
170 ml (amount infused) = 95 ml remain to be infused.
7. Answer: 2
8. Answer: 1 or 0.5
9. Answer: 1
Rationale: The tube feeding is administered at 75 ml/hour for 11 hours (0700 - 1800) and
then turned off for one hour because the residual is greater than 200 ml. 11 hours x 75
ml/hr = 825 ml. Three doses of 20 ml of medication are administered, with 10 ml of
water used to flush the GT before and after each dose. 20 ml x 3 doses = 60 ml; 10 ml
(flush) x 2 x 3 doses = 60 ml; so 825 ml + 60 ml + 60 ml = 945 ml. 250 ml of residual is
removed and not replaced. 945 ml - 250 ml = 695 ml total fluid balance (Intake - output).
12. Answer: 1
13. Answer: 3
14. Answer: 3
Rationale: Using the child's BSA, 0.7 m2, calculate the mg/dose, 600 mg x 0.7 m2 = 420
mg/day/3 doses = 140 mg/dose
18. Answer: 2
Rationale: Calculate each drug component dose, using the formula, D/H 125 mg / 62.5
mg (atovaquone) = 2 combined with 50 mg / 25 mg (proguanil) = 2. The child should
receive 2 tablets.
19. Answer: 2
Rationale: After reconstituting the medication vial, the nurse adds the 5 ml of medication
to the 50 ml of sterile water to result in a 55 ml volume to infuse in 30 minutes. Using the
formula, Volume/Time = 55 ml / 0.5 hours = 110 ml/hour
Rationale: Determine the total volume needed at 80 ml/hour x 4 hours = 320 ml. Use the
formula, Desired strength/strength on Hand x Volume = 50/100 x 320 = 160 ml of
Osmolite® enteral formula, which must be diluted to half strength. Or use ratio and
proportion, Desired strength (1/2 = 1 part : 2 parts) :: Volume of full strength : Total
Desire volume 1 : 2 :: X : 320 ml 2X = 320, and X = 160 ml of Osmolite® enteral
formula, full strength 320 ml total volume - 160 ml of full-strength formula = 160 ml of
water to create 1/2 strength or 50% concentration.
22. Answer: 10
23. Answer: 18
Rationale: Adjust the infusion to 900 units/hour (1,000 units/hour minus 100 units/hour
per protocol). Using the formula, D/H x Q, 900 units/1 hour divided by 25,000 units x
500 ml = 90/5= 18 ml/hour.
24. Answer: 3
Rationale: Using the formula, D/H x Q, 0.5 milliunits / 10,000 milliunits x 1000 ml =
0.05 ml/minute. Multiply by 60 minutes = 3 ml/hour.
25. Answer: 3
Rationale: Using the known equivalent, 1 gram = 1000 mg, the nurse should first
convert the dose to the same unit of measurement, which is 0.3 gram = 300 milligram.
Using the formula, Desired / Available x 1 capsule = 300/100 x 1 = 3 capsules.
26. Answer: 2
29. Answer: 97
Rationale: Determine the maximum number of mg this client should receive in a day:
48.5 kg x 8 mg/kg/day = 388 mg/day. Next determine how many mg the nurse should
deliver each dose: 388 mg/4 doses = 97 mg.
30. Answer: 4
32. Answer: 83
Rationale: First convert hours to minutes: 10 hrs x 60 = 600 minutes. Using the formula
Volume/Time x drop factor: 1000 ml /600 minutes = 1.66666 x 60 = 100 gtts minute.
34. Answer: 6
37. Answer: 24
Rationale: First calculate the number of mcg/hour: 400 mcg x 60 minutes = 24000
mcg/hour. Next calculate the number of ml/hour needed to administer 24,000 mcg/hour:
100,000 mcg: 100ml :: 24,000 mcg : X 100,000/24,000 :: 100/X 100,000X = 2,400,000 X
= 24 ml/hour.
38. Answer: 28
39. Answer: 8
Rationale: First convert the weight into kilograms: 148 pounds/2.2 kg = 67 kg. Next
calculate the number of mcg/kg/minute: 5 x 67 x 1 minute = 335 mcg/min. Calculate the
number of mcg/hour: 335 x 60 minutes = 20,100 mcg/hour. Now calculate the number of
ml/hour needed to administer 20,100 mcg/hour: 600,000 mcg : 250 ml :: 20,100 mcg : X
ml 600,000/20100 :: 250/X 600,000X = 5,02500 X = 8.375 (rounded to) 8 ml/hour.
40. Answer: 2
Rationale: Using the known equivalent, 1 gram = 1000 mg, the nurse should first
convert the dose to the same unit of measurement, which is 1 gram = 1000 mg. Using the
formula, Desired / Available x 1 tablets: 1000 mg / 500 mg x 1 = 2 tablets
Rationale: First convert gram to milligram: 1 gm = 1000mg .572 gram x 1000 = 572 mg.
Next use the formula D/H x Q: 572/250 x 1 = 2.288 (rounded to) 2.3 ml.
42. Answer: 2
Rationale: First, using the formula, Desired dose/dose on Hand x Quantity of volume on
hand (D/H x Q), 10 mg / 5 mg x 5ml = 10 ml. Next using the known conversion of 5 ml =
1 tsp: 5 ml : 1 tsp :: 10 ml : X 5 / 10 : 1 / X 5X = 10 X = 2
Rationale: Using the conversion of 1 gram = 1000 mg: 0.1 gram = 100 mg 100 mg = 1
capsule
44. Answer: 1
Rationale: Using the conversion of 1 gram = 1000 mg: 0.1 gram = 100 mg 100 mg = 1
capsule
45. Answer: 12
Rationale: First calculate the mg/kg dosage needed: 0.75 mg x 80 kg = 60 mg needed.
Then calculate Desired / Have x ml 60 mg / 100 mg x 20 ml = 12 ml.
47. Answer: 78
Rationale: First calculate the number of mg the client will receive in 1 hour: 0.1 mg x 78
kg = 7.8 mg/hour. Next calculate the number of ml containing 7.8 mg of medication: 25
mg : 250 ml :: 7.8 mg : X 25 mg/ 7.8 mg :: 250 ml/X 25X = 1950 X = 78 ml/hour.
50. Answer: 14
Rationale: Volume/Time (minutes) x drop factor (gtt/ml) = 85 ml/ 60 minutes x 10 gtt/ml
= 14.16 = 14 gtt/minute