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    Pragya Devi
    Question bank on Biostatistics on random variables and distributions

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    Question bank on Biostatistics on random variables and distributions

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    Question bank on Biostatistics on random variables and distributions

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    9 views2 pages

    Quiz

    Uploaded by

    Pragya Devi
    Question bank on Biostatistics on random variables and distributions

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 2

    BBL772: Data Analytics and Informatics in Biotechnology

    Quiz I

    Total: 10 Marks; 30 minutes 16/10/2023

    Multiple choice questions: 1x6


    1. The variability of the mean of a sampling distribution increases with sample size. True/False

    2. The best description of the sampling distribution of a sample statistic is the distribution of the values of the statistic
    a. for all individuals of the sample,
    b. for some samples of the fixed size chosen from the population,
    c. for some samples of different sizes chosen from the population,
    d. for all possible samples of the fixed size chosen from the population.

    3. The mean and standard deviation of a population is 250 and 20, respectively. What is the probability of selecting a
    sample of size 25 with a mean of 240?
    a. 0.69 b. 0.009
    c. 0.31 d. 0.006

    4. What happens to a sampling distribution if the sample size increases?


    a. It becomes narrower and approaches normal,
    b. It becomes wider and approaches normal,
    c. It becomes narrower and deviates from normal,
    d. It becomes wider and deviates from normal.

    5. In a mouse-model testing for a particular skin cancer, 78% of all mice develops some change in pigmentation. A
    student selects a random sample of 32 mice and 72% of them show change in pigmentation. Which of the following
    is true?
    a. 72% is a population and 78% is a sample,
    b. 78% is a parameter and 72% is a statistic,
    c. 78% is a population and 72% is a sample,
    d. 72% is a parameter and 78% is a statistic.

    6. From a population of N = 15, what is the probability of choosing any unique simple random sample of n = 3?
    a. 0.0007 b. 0.0095
    c. 0.0003 d. 0.0022

    15
    The number of ways you can choose unique samples of size 3 from a population of size 15 is: ! %. Therefore, the
    3
    ! !
    probability of making such a choice = !# = &## = 0.0022.
    " %
    $

    7. A recent article by Pedroletti et al reported the maximal nitric oxide diffusion rate in a sample of 35 asthmatic
    schoolchildren and 40 controls as mean ± standard error of the mean. For asthmatic children, they reported
    3.5± 0.4 nL/s, while for the control group they reported 0.7 ± 0.1 nL/s. For each group answer the following:
    a. What was the sample standard deviation?
    b. What is the 95% confidence interval for the mean maximal nitric oxide diffusion rate of the population?
    c. What assumptions are necessary for the validity of the confidence interval you constructed?

    1+2+1 = 4
    '
    a. Formula for standard error: 𝑆𝐸 = where 𝑠 is the sample standard deviation and 𝑛 is the sample size.
    √)

    Therefore, we have the sample standard deviation as: 𝑠 = 𝑆𝐸 × √𝑛

    For the asthmatic group we have: 𝑠* = 𝑆𝐸* × √𝑛 = 0.4 × √35 = 2.37 𝑛𝐿/𝑠

    For the control group we have: 𝑠+ = 𝑆𝐸+ × √𝑛 = 0.1 × √40 = 0.63 𝑛𝐿/𝑠

    b. Formula for 95% confidence interval: sample mean ± 𝑟𝑒𝑙𝑖𝑎𝑏𝑖𝑙𝑖𝑡𝑦 𝑐𝑜𝑒𝑓𝑓𝑖𝑐𝑖𝑒𝑛𝑡 × 𝑆𝐸


    Here, the sample sizes are 35 and 40 for the two groups, both of which are bigger than 30. So, we assume
    normal distributions. Thus, we can use the Z-table to estimate the reliability coefficient. We know for 95%
    confidence interval this number is 1.96.

    Therefore, for the asthmatic group, the 95% confidence interval is: 3.5 ± 1.96 × 𝑆𝐸* = 3.5 ± 1.96 × 0.4 = 3.5 ±
    0.78 𝑛𝐿/𝑠

    For the control group, the 95% confidence interval is: 0.7 ± 1.96 × 𝑆𝐸+ = 0.7 ± 1.96 × 0.1 = 0.7 ± 0.196 𝑛𝐿/𝑠

    c. The assumptions here are:

    (i) The sample standard deviation is an approximate measure of the population standard deviation

    (ii) The sample sizes are big enough so that the central limit theorem is applicable. The sampling distribution of
    maximal nitric oxide diffusion rate is approximately a normal distribution.

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