WATER SOLULE (2) V
WATER SOLULE (2) V
WATER SOLULE (2) V
by
Prof. Dr . Ahmed Ameen
Prof . Of Nutrition
B-5 Pantothenic Acid
1998 adequate intake (AI)
Adults: 5 mg/day
Chief functions in the body
Part of coenzyme A, used in energy
metabolism
Significant sources
Widespread in foods
Organ meats, mushrooms, avocados, broccoli,
whole grains
Easily destroyed by food processing
Pantothenic Acid
Deficiency symptoms
Vomiting, nausea, stomach cramps
Insomnia, fatigue, depression, irritability,
restlessness, apathy
Hypoglycemia, increased sensitivity to
insulin
Toxicity symptoms: none reported
B-7 Biotin
Fortified
grains
Leafy green
vegetables,
legumes,
seeds
Liver
Folate
Deficiency symptoms
Spina bifida
Anemia (macrocytic or large-cell
type)
Smooth, red tongue
Mental confusion, weakness,
fatigue, irritability, headache
Vitamin B12
Other names: cobalamin (and related
forms)
Chief functions in the body
Part of coenzymes methylcobalamin and
deoxyadenosylcobalamin used in new cell
synthesis
Helps to maintain nerve cells
Helps to break down some fatty acids and
amino acids
B-12 Cobalamin
Important in:
proper nerve function
production of red blood cells
metabolizing fats and proteins
prevention of anemia
DNA reproduction
energy production?
Vitamin B12
1998 RDA
Adults: 2.4 g/day
Absorption
Vitamin B12 is absorbed from ileum,for its
proper absorption it requires:
Presence of HCL, and Intrinsic factor(IF)
Vitamin B12
Significant sources
Vitamin B12, or cobalamin, is naturally found in
animal foods.
Animal products (meat, fish,
poultry, shellfish, milk, cheese,
eggs)
Fortified cereals
Easily destroyed by microwave cooking
Deficiency due to vegan diet or
lack of intrinsic factor
Vitamin B12
Deficiency symptoms
pernicious anemia (Deficiency of
folate or B12 produces pernicious
anemia)
Anemia (large-cell type)
Fatigue, degeneration of peripheral
nerves progressing to paralysis
Toxicity symptoms: none reported
Warnings
Deficiency
May be due to dietary factors, gastric factors as in post
gastrostomy and in strict vegetarians .
If absorption is prevented by lack of intrinsic factor it will
cause pernicious anemia.
Megaloblastic anemia appears due to B12 deficiency
Vegetarians need to look for fortified sources (soy
milk, supplements).
Elderly often have trouble absorbing.
Vitamin C
Vitamin C
Other name: ascorbic acid
Unlike most mammals, humans do not have the ability to make
their own vitamin C. Therefore, we must obtain vitamin C through
our diet. Chief functions in the body
Collagen synthesis ,Strengthens blood vessel walls, provides
matrix for bone growth
Antioxidant
Thyroxin synthesis
Amino acid metabolism
Strengthens resistance to infection
Helps in absorption of iron
Ascorbic acid (Toxic to viruses,bacteria, and some malignant
tumor cells)
Vitamin C
2000 RDA
Men: 90 mg/day
Women: 75 mg/day
Smokers: + 35 mg/day
Upper level for adults: 2000 mg/day
Needs increase with
infection, burns, surgery & smokers
Easily destroyed by heat and oxygen
Vitamin C
Sources
Citrus fruits
Cabbage-type vegetables,
dark green vegetables (such
as bell peppers and broccoli)
Cantaloupe, strawberries
Lettuce, tomatoes, potatoes
Papayas, mangoes
Vitamin C
Deficiency disease: scurvy
Deficiency symptoms
Anemia (small-cell type)
Atherosclerotic plaques
Hemorrhages under the skin, bone
fragility, joint pain
Poor wound healing, frequent infections,
bleeding gums, loosened teeth
Muscle degeneration and pain, hysteria,
depression, rough skin, blotchy bruises
Vitamin C
Toxicity symptoms - >2 gms/day
Nausea, abdominal cramps, diarrhea
Headache, fatigue, insomnia, rashes
Interference with medical tests (false-
negative urine glucose test),
aggravation of gout symptoms, urinary
tract problems, kidney stones (oxalate)