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CLINICAL EVIDENCE AND GUIDELINES FOR CANCER PATIENTS

Recommended Protein Intake:

 Cancer patients need 1.2 to 2.0 g/kg/day of protein, depending on health, cancer type,
treatment stage, and nutritional status.

Rationale for Increased Protein Needs:

 Cancer Cachexia: Prevents muscle wasting and preserves lean body mass.

 Treatment Effects: Surgery, chemotherapy, and radiation increase protein needs for tissue
repair and immune function.

 Immune Function: Adequate protein intake supports immune health, reducing infection risks.

Protein Sources:

 Animal Sources: Lean meats, poultry, fish, eggs, dairy.

 Plant-Based Sources: Legumes, soy products, tofu, tempeh, whole grains.

 Supplements: Protein shakes, powders, or oral nutritional supplements.

 Leucine-Rich Foods: Dairy, eggs, soy—important for muscle synthesis.

Protein Intake Across Cancer Stages:

 Pre-treatment & Early Treatment: Higher end of the range (1.5–2.0 g/kg/day) to maintain
muscle mass.

 During Treatment: Small, frequent meals may be needed due to nausea or appetite loss.

 Post-treatment/Recovery: Protein remains essential to rebuild muscle.

 Palliative Care: Focus on comfort, but adequate nutrition can improve quality of life.

Considerations for Special Cancer Types:

 Head & Neck Cancer: May require enteral nutrition due to swallowing issues.

 Gastrointestinal Cancers: Digestive issues may necessitate easily digestible protein sources and
supplements.

Special Guidelines & Clinical Trials:

 ESPEN Guidelines: Recommend early screening for malnutrition and individualized nutritional
plans.

 Clinical Trials: Investigate higher protein intake and leucine's role in muscle preservation.

Potential Risks & Monitoring:

 Monitor kidney function and nutritional status, especially in patients with coexisting conditions
(e.g., renal impairment).

 Regularly assess muscle mass, weight, and overall energy intake.


CLINICAL EVIDENCE AND GUIDELINES FOR CANCER PATIENTS

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