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    Eosinophil

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    manognaaaa
    The document describes the key characteristics of various white blood cells and cells involved in immune responses. Eosinophils contain granules that release enzymes and are attracted to sites of allergic reactions. Lymphocytes have minimal cytoplasm and granular chromatin. Neutrophils have lobed nuclei and different types of granules. Monocytes stain positively for lysosomal enzymes and surface molecules. Mast cells contain metachromatic granules and degranulate during hypersensitivity reactions. Histiocytes and macrophages originate from the bone marrow. Epithelioid cells form from fused histiocytes. Langhans giant cells form in tuberculosis granulomas. Touton giant cells contain a foamy central cytoplasm. Plasma cells have abundant

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    Eosinophil

    Uploaded by

    manognaaaa
    115 views24 pages
    The document describes the key characteristics of various white blood cells and cells involved in immune responses. Eosinophils contain granules that release enzymes and are attracted to sites of allergic reactions. Lymphocytes have minimal cytoplasm and granular chromatin. Neutrophils have lobed nuclei and different types of granules. Monocytes stain positively for lysosomal enzymes and surface molecules. Mast cells contain metachromatic granules and degranulate during hypersensitivity reactions. Histiocytes and macrophages originate from the bone marrow. Epithelioid cells form from fused histiocytes. Langhans giant cells form in tuberculosis granulomas. Touton giant cells contain a foamy central cytoplasm. Plasma cells have abundant

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    The document describes the key characteristics of various white blood cells and cells involved in immune responses. Eosinophils contain granules that release enzymes and are attracted to sites of allergic reactions. Lymphocytes have minimal cytoplasm and granular chromatin. Neutrophils have lobed nuclei and different types of granules. Monocytes stain positively for lysosomal enzymes and surface molecules. Mast cells contain metachromatic granules and degranulate during hypersensitivity reactions. Histiocytes and macrophages originate from the bone marrow. Epithelioid cells form from fused histiocytes. Langhans giant cells form in tuberculosis granulomas. Touton giant cells contain a foamy central cytoplasm. Plasma cells have abundant

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    115 views24 pages

    Eosinophil

    Uploaded by

    manognaaaa
    The document describes the key characteristics of various white blood cells and cells involved in immune responses. Eosinophils contain granules that release enzymes and are attracted to sites of allergic reactions. Lymphocytes have minimal cytoplasm and granular chromatin. Neutrophils have lobed nuclei and different types of granules. Monocytes stain positively for lysosomal enzymes and surface molecules. Mast cells contain metachromatic granules and degranulate during hypersensitivity reactions. Histiocytes and macrophages originate from the bone marrow. Epithelioid cells form from fused histiocytes. Langhans giant cells form in tuberculosis granulomas. Touton giant cells contain a foamy central cytoplasm. Plasma cells have abundant

    Copyright:

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    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    of 24

    EOSINOPHIL

    12-17 .

    Strong eosinophilc granules in the cytoplasm and a

    bilobed nucleus. Hydrolytic enzymes in the granules: peroxidase and arylsulphatase. Attracted to th site of anaphylactoid reaction by mast cell degranulation. Eosinophilia seen in pemphigus foliaceous, vegetans and granuloma faciale, mycosis fungoides, urticaria, atopic dermatitis.

    LYMPHOCYTE

    8 .

    Small round deeply basophilic nucleus.


    Chromatin granules. Narrow rim of cytoplasm. Leucocyte common antigen-immunomarker of

    lymphocyte.

    NEUTROPHIL

    10-15 .

    Salt and pepper appearance.


    Lobulated nucleus with several segments connected only

    by a bridge of nucleoplasm. Two types of pale pink granules. a) azurophilic granules (20%) b) specific granules.

    MONOCYTE

    12-15 m.

    Stain for lysosomal enzymes like acid phosphatase.


    Intracytoplasmic molecules(CD 68), detected in paraffin

    sections. Antitrypsin and anti chemotrypsin : immunemarkers.

    MAST CELL

    Bone marrow derived cells seen in dermis.

    Oval to spindle shaped with a centrally located round to

    oval nucleus. Metachromatic granules in the cytoplasm. Stain with toluidine blue, alcian blue, giemsa. Mast cell degranulation in immediate and delayed hypersensitivity

    HISTIOCYTE

    Also called macrophages.

    20-80.
    Bone marrow origin. Clear vesicular light staining nucleus. Clear nuclear

    membrane. Larger and contain more lysososmal enzymes compared monocytes.

    EPITHELOID CELL

    Spindle shaped or elongated cell with Large, vesicular

    nucleus with well defined nuclear membrane and pale cytoplasm. Cells formed by fusion of histiocytes. Cell margins indistinct. Seen in tuberculoid and sarcoid granulomas.

    LANGHANS GIANT CELL

    Formed by fusion of many epitheloid giant cells, under the influence of good host cell immunity. Seen in tuberculoid granulomas.

    TOUTAN GIANT CELL

    Central foamy cytoplasm, floret or wreath-like nuclear

    arrangement at the periphery. Seen in xanthomas and juvenile xanthogranulomas.

    FOAM CELL

    FOREIGN BODY GIANT CELL

    Formed by fusion of many macrophages.

    Seen in suppurative and foreign body granulomas.

    PLASMA CELL

    10.

    Abundant deeply basophilic homogenous cytoplasm.


    Eccentrically placed round nucleus with a deeply

    basophilic coarse, chromatin attached to the nuclear membrane.(cartwheel appearance)

    TUBERCULOID GRANULOMA

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