Cancer of Reproductive System
Cancer of Reproductive System
Cancer of Reproductive System
Mariane S. Montemayor
BREAST CANCER
• A cancer that starts in the
cells of the breast in
women and men
BREAST CANCER
Risk factors you cannot Risk Factor you can change
change lifestyle choices
• Gender- • Nullipara
• Age • Use of birth control
• Genetic risk factors pills
• Race • Postmenopausal
hormone therapy (PHT)
• Personal history of
breast cancer • Use of alcohol
• Menstrual periods • Being overweight or
obese
• Treatment with DES
BREAST CANCER
Cause: Study
• Lesions to DNA
• Exact causes such as genetic
of Cancer is mutations
UNKNOWN • Abnormal growth
factor- signaling
• Inherited defects
in DNA repair
genes
Paget's disease
• named after Sir James
Paget
• include redness and
mild scaling and flaking
of the nipple skin and
resembles eczema, and
can be itchy
Male Breast Cancer
• Men with breast cancer
usually have lumps that
can be felt
• men have breast tissue
and that they can
develop breast cancer.
BREAST CANCER
SYMPTOMS
• a “lump” in the surrounding breast tissue.
• changes in breast size or shape, skin dimpling,
nipple inversion, or spontaneous single-nipple
discharge
• “Mastodynia” – breast pain
• peau d'orange- pain, swelling, warmth and
redness throughout the breast, as well as an
orange-peel texture to the skin- inflammatory
breast cancer (IBC)
• Paget's disease of the breast
BREAST CANCER
Diagnostic Test
common methods
screening are:
self and clinical breast
exams
Incision and biopsy)
mammography
Magnetic Resonance
Imaging (MRI)
Genetic testing may also
used
BREAST CANCER
Treatment
surgery when the tumor is
localized
adjuvant hormonal
therapy (with tamoxifen
or an aromatase inhibitor)
Adjuvant therapy
Hormone Therapy
Chemotherapy
Radiotherapy
Interstitial laser
thermotherapy (ILT)
Cancer of the Reproductive
System
Female
Reproductive System
Ovary
Uterus
Endometrial
Uterus – Cervical
Vagina/Vulva
Ovarian Cancer
• is a cancerous growth arising
from different parts of the
ovary
• most cases, there are no
known causes
• called a “silent killer”
• Ovarian cancer can develop
at any age
Ovarian Cancer
• Risk factors
• Genetic risk factors
• Increasing age- menopausal women
• Nullipara
• Early menstrual cycles- start before 12
years old and late menopausal
• Use of estrogens or hormone replacement
therapy
• Use of Talc, High fat diet
Ovarian Cancer
Symptoms
• pelvic pressure or • pain or swelling in the
frequent urination abdomen
• pain during intercourse
• unexplained changes in • vaginal bleeding in post-
bowel habits menopausal women
Ovarian Cancer
Diagnostic Exams
• PE
• pelvic examination
• CA-125 assay
• one or more various imaging procedures
(MRI, CT’s scan, UTZ)
• a lower GI series, or barium enema
• diagnostic laparoscopy
Treatment Ovarian Cancer
Treatment
• Surgery- oophorectomy, bilateral
oophorectomy,TAHBSO
• Chemotherapy- via the lymphatic
system or the blood stream
• Radiation
UTERINE CANCER
• Cancer of uterine cavity
• Divided into two primary forms
Endometrial Cancer
Cervical Cancer
Endometrial Cancer
• develops when the cells that make up the
endometrium become abnormal and grow
uncontrollably
• exact cause of endometrial cancer is
unknown
Endometrial Cancer
Endometrial cancer
• Risk Factor
• CAUSES Age- age of 50 and above
Obesity
• high levels of
Estrogen replacement
estrogen
therapy
Diabetes Hypertension
Early first menstruation or
late menopause
Tamoxifen
Genetic factors
Nullipara women
Symptoms of Endometrial
cancer
• Vaginal bleeding • Anemia
menorrhagia
metrorrhagia • Lower abdominal
in premenopausal women pain or pelvic
in women older than 40: cramping
extremely long, heavy, • Thin white or
or frequent episodes of clear vaginal
bleeding (may indicate
premalignant changes) discharge in
postmenopausal
women.
Diagnostic Exams for
Endometrial cancer
• Pap smear
• Endometrial curettage
• Hysteroscopy
• Endometrial biopsy or aspiration
• Transvaginal ultrasound
• TruTest- uses the small flexible Tao
Brush to brush the entire lining of the
uterus
Treatment for Endometrial
cancer
• Surgical treatment – TAHBSO
Abdominal hysterectomy more prefer than
vaginal hysterectomy
• Radiation therapy
• Chemotherapy
• Hormone therapy
CERVICAL TUMOR/CANCER
•
• a disease in which the cells
of the cervix become
abnormal and start to grow
uncontrollably, forming
tumors.
• third most common cancer
of the female reproductive
tract
CERVICAL TUMOR/CANCER
• RISK FACTOR:
Male
• TESTICULAR
CANCER
• PENILE CANCER
TESTICULAR CANCER
• cancer that develops
in the testicles
• Rare but usually
occur between ages
15-35
• No known
etiology/cause
TESTICULAR CANCER
Risk Factor
• major risk factor for the
development of testis cancer is
cryptorchidism
• inguinal hernia
• mumps orchitis
• sedentary lifestyle
• hormones
TESTICULAR CANCER
SYMPTOMS
• A burning sensation
3 times the original size.