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    Composition of Blood

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    Jalajarani Aridass
    The document discusses the composition of blood. It states that blood consists of plasma and cellular components, with plasma making up 55% of blood and cellular components making up 45%. The main cellular components are red blood cells (99%), white blood cells, and platelets. Plasma contains water, proteins, nutrients, wastes, and gases. The document provides details on the components and functions of plasma, red blood cells, white blood cells, and platelets. It also lists normal reference ranges for components of a complete blood count.

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    Composition of Blood

    Uploaded by

    Jalajarani Aridass
    244 views21 pages
    The document discusses the composition of blood. It states that blood consists of plasma and cellular components, with plasma making up 55% of blood and cellular components making up 45%. The main cellular components are red blood cells (99%), white blood cells, and platelets. Plasma contains water, proteins, nutrients, wastes, and gases. The document provides details on the components and functions of plasma, red blood cells, white blood cells, and platelets. It also lists normal reference ranges for components of a complete blood count.

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    The document discusses the composition of blood. It states that blood consists of plasma and cellular components, with plasma making up 55% of blood and cellular components making up 45%. The main cellular components are red blood cells (99%), white blood cells, and platelets. Plasma contains water, proteins, nutrients, wastes, and gases. The document provides details on the components and functions of plasma, red blood cells, white blood cells, and platelets. It also lists normal reference ranges for components of a complete blood count.

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd
    Download as ppt, pdf, or txt
    244 views21 pages

    Composition of Blood

    Uploaded by

    Jalajarani Aridass
    The document discusses the composition of blood. It states that blood consists of plasma and cellular components, with plasma making up 55% of blood and cellular components making up 45%. The main cellular components are red blood cells (99%), white blood cells, and platelets. Plasma contains water, proteins, nutrients, wastes, and gases. The document provides details on the components and functions of plasma, red blood cells, white blood cells, and platelets. It also lists normal reference ranges for components of a complete blood count.

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    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd
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    COMPOSITION OF BLOOD

    DR. AYESHA JUNAID

    MBBS,MCPS,FCPS.
    Professor of Pathology
    Consultant Haematology
    Incharge Blood Transfusion Services SIH

    OBJECTIVES: COMPOSITION OF BLOOD


    Composition of blood.
    Little bit of functions of blood.
    Plasma and its composition.
    CELLULAR COMPONENTS:
    RBCs: their structure, function and
    count.
    WBCs: their types, structure, function &
    count.
    Platelets: their structure, function and
    count.

    COMPOSITION OF BLOOD
    5 LITRE
    55% PLASMA
    45% CELLULAR
    COMPONENTS

    COMPOSITION OF BLOOD
    Blood is slightly denser and approximately 3-4
    times more viscous than water, blood consists of
    cells which are suspended in a liquid.
    Cellular Components
    99% red blood cells, with
    white blood cells and
    platelets making up the remainder.
    Water, of blood has amino acids, proteins,
    carbohydrates, lipids, hormones, vitamins,
    electrolytes, dissolved gases, and cellular
    wastes.

    COMPOSITION OF BLOOD
    By volume.
    Plasma is about 92% water, with plasma
    proteins as the most abundant solutes.
    The main plasma protein groups are
    albumin
    globulin
    fibrinogen
    The primary blood gases are
    oxygen, carbon dioxide, and
    nitrogen.

    COMPOSITION OF BLOOD
    Centrifuged blood:
    Plasma 55%
    Buffy coat
    WBCs
    <1%
    Erythrocytes
    Hematocrit
    45%.


    Plasma.
    COMPOSITION
    90% water
    10% solutes

    OF BLOOD

    Ions, e.g., Na+, Cl-, Ca++


    Nutrients, e.g., simple sugars, amino
    acids, lipids
    Wastes, e.g., urea, ammonia, CO2
    Miscellaneous: O2, hormones, vitamins,
    plasma proteins.

    COMPOSITION OF BLOOD
    Plasma Proteins.
    Albumin
    Helps control osmotic pressure
    Helps control diffusion of water
    Globulin
    Includes antibodies
    Transport proteins (lipids, iron, copper, etc.)
    Fibrinogen
    Involved in clotting

    COMPOSITION OF BLOOD
    Serum: Blood plasma from which the
    protein fibrinogen, which causes clotting
    of the blood, has been removed.
    For all blood chemistry serum of blood is
    preferred over plasma

    COMPOSITION OF BLOOD
    WBC, Total.............(4000/L -11000/L)
    RBC, Total......M(4.5 - 6.5)m/L, F(3.85.8)m/L.
    Hemoglobin... M(13.0-18.0)g/dL F(11.6-16.5)g/dL
    HCT......................... M(40 - 54)% F(38 - 47)%
    MCV..................... (80 - 90)fL
    MCH....................... (27 - 32)pg
    MCHC..................... (33 - 38)g/dL
    Platelet Count....................(150,000-400,000)/L

    COMPOSITION
    Red
    cell indices

    MCV
    MCH
    MCHC
    RDW

    OF BLOOD

    COMPOSITION OF BLOOD
    MCV
    is a measure of the average red
    cell volume
    HCT/RBC
    Normocytic 75-95 fl
    Macrocytic >95fl
    Microcytic <75fl

    PERIPHERAL FILM

    COMPOSITION OF BLOOD
    MCH
    Is the average mass of Hemoglobin
    per red blood cell.
    HB/RBC
    MCH:27 -31 pg
    Anemia : low MCH
    Cannot increase than normal

    COMPOSITION OF BLOOD
    MCHC
    is a measure of the concentration of
    Hemoglobin in a given volume of
    packed red blood cells.
    MCHC:32 to 36 g/dl
    Decreases in anemia

    COMPOSITION OF BLOOD
    RDW
    is an index of the variation in cell
    volume within the red cell population
    RDW = (Standard deviation mean
    cell volume) x 100

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