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    Current Concepts in The Pathogenesis and Treatment of Chronic Suppurative Otitis Media

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    furqon al
    Chronic suppurative otitis media (CSOM) is a common chronic ear infection worldwide characterized by a perforated eardrum and persistent drainage from the ear. The most common pathogens that cause CSOM are Pseudomonas aeruginosa and Staphylococcus aureus. Treatment involves regular cleaning of the infected ear, topical antibiotic drops, and sometimes systemic antibiotics or surgery. Complications can include conductive or sensorineural hearing loss. Future treatments may involve using bacteriophages as they are considered safe and effective against resistant bacterial strains.

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    Current Concepts in The Pathogenesis and Treatment of Chronic Suppurative Otitis Media

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    furqon al
    65 views31 pages
    Chronic suppurative otitis media (CSOM) is a common chronic ear infection worldwide characterized by a perforated eardrum and persistent drainage from the ear. The most common pathogens that cause CSOM are Pseudomonas aeruginosa and Staphylococcus aureus. Treatment involves regular cleaning of the infected ear, topical antibiotic drops, and sometimes systemic antibiotics or surgery. Complications can include conductive or sensorineural hearing loss. Future treatments may involve using bacteriophages as they are considered safe and effective against resistant bacterial strains.

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    Chronic suppurative otitis media (CSOM) is a common chronic ear infection worldwide characterized by a perforated eardrum and persistent drainage from the ear. The most common pathogens that cause CSOM are Pseudomonas aeruginosa and Staphylococcus aureus. Treatment involves regular cleaning of the infected ear, topical antibiotic drops, and sometimes systemic antibiotics or surgery. Complications can include conductive or sensorineural hearing loss. Future treatments may involve using bacteriophages as they are considered safe and effective against resistant bacterial strains.

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    Download as pptx, pdf, or txt
    65 views31 pages

    Current Concepts in The Pathogenesis and Treatment of Chronic Suppurative Otitis Media

    Uploaded by

    furqon al
    Chronic suppurative otitis media (CSOM) is a common chronic ear infection worldwide characterized by a perforated eardrum and persistent drainage from the ear. The most common pathogens that cause CSOM are Pseudomonas aeruginosa and Staphylococcus aureus. Treatment involves regular cleaning of the infected ear, topical antibiotic drops, and sometimes systemic antibiotics or surgery. Complications can include conductive or sensorineural hearing loss. Future treatments may involve using bacteriophages as they are considered safe and effective against resistant bacterial strains.

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    Current concepts in the

    pathogenesis and treatment of


    chronic suppurative otitis media

    dr. Afif Zjauhari, Sp.THT-KL


    http://www.free-powerpoint-templates-design.com
    INTRODUCTION
    • No inflammation
    • No perforated
    Tympanic
    Membrane (TM)
    • No fluid
    INFECTION
    ALLPPT
    Layout
    Clean Text
    Slide
    for your Acute Otits Media:
    Presentation • Sign of
    inflammation
    • Presence of fluid
    Chronic Suppurative
    Otitis Media:
    Acute Otits Media
    Inadequate • Perforated TM
    medication • Presistent
    drainage
    INSIDENCE AND
    EPIDEMIOLOGY
    Get a modern PowerPoint Presentation
    that is beautifully designed.

    Get a modern PowerPoint Presentation


    that is beautifully designed.

    Get a modern PowerPoint Presentation


    that is beautifully designed.
    Greenland
    • 0 – 4 yr 14 %
    • 3-8 yr 19 -20%
    MIKROBIOLOGY
    The most common AOM is
    cause of OM is predominantly
    bacterial infection caused by
    India

    P. aeruginosa
    Nepal
    The most common
    pathogen that Followed by
    cause CSOM are
    Singap
    ore

    Nigeria
    S. aureus
    Pakist
    an
    P. aeruginosa

    The most common


    Iran pathogen that Followed by
    cause CSOM are

    Saudi
    Arabia

    S. aureus
    The differences in
    the various
    studies could be
    due to

    The differences in
    the patient Geographical
    population variation
    studied
    More than
    one type
    of
    bacterial

    CSOM can also


    be characterized Viral
    pathogen
    by co-
    infections

    Fungi
    enter

    External
    canal Middle
    P. aeruginosa ear

    Bacteria damage
    tissues
    1

    Inactivayes antibiotics Interferes with


    by various enzymes and normal body
    toxins 3 defences 2
    HEARING LOSS
    Hearing loss is the most common
    sequela of CSOM

    can cause

    CHL (conductive SNHL (sensorineural


    hearing loss) hearing loss)
    obstruction in the inner ear damage
    transmission of sound waves (cochlea)
    CHL,
    result
    from :

    Effusion Tympanic
    membrane
    (pus) perforation

    Can hinder the conductance of sound to the inner ear


    SNHL
    Toxins

    Can cause
    Infection of Penetrate the cochlear
    the middle Inflammatory round window
    mediators damage
    ear membrane and
    pass into the
    inner ear

    Nitrit oxide, arachidonic


    acid, histamine,
    cytokines
    The cochlea has 3 rows of outer
    hair cells (OHCs) and 1 row of
    inner hair cells (IHCs)

    OHC help in the amplification and


    tuning of sound waves

    IHC help to converting mechanical energy of


    sound into an electrical impuls
    Any damage to outer or inner hair cells can cause severe
    hearing impairment, which can be irreversible and permanent
    THERAPY
    Aural Toilet Topical antibiotics
    Otic insufflation powder

    Keeping draining (chloramphenicol,


    sulfamethoxazol, and
    ear clean and dry
    amphotericin B)

    2-3x/ weeks
    OTOTOPICAL ANTIBIOTICS
    Quinolones
    +
    Corticosteroids
    When ???
    Antibiotic
    drops + aural -Inflammation of the external
    toilet auditory canal or middle ear
    mucosa
    -Granulation tissue is present

    Therapy CSOM
    SYSTEMIC ANTIBIOTICS
    Primary treatment
    (3 weeks)

    Failure

    P. aeruginosa &
    Oral Antibiotic MRSA:
    • Quinolones
    • Trimetropin-
    Sulfametoxazole
    Amoxiclav Sulfafurazole

    Erythromycin
    SURGERY

    Tympanomastoidectomy: Mastoidectomy:
    • Chronic Cholesteatomatous OM • Abscess formation in the mastoid

    Tympanoplasty:
    • 6 to 12 months after resolution of the infection.
    Recurrent Disease

    Cholesteatoma
    Oral Antibiotics Only
    Non Antibiotic Drops

    Non-compliance with the treatment


    P. aeruginosa or MRSA regimen
    CONCLUSIONS
    • CSOM  common chronic infectious disease worldwide.
    • Topical antibiotics, (limited to non ototoxic).
    • Surgery  risks of worsening hearing

    Bacteriophages
     Safe
     Economical Resistant bacteria
     Self-replicating
     Effective
    bactericidal
    Thank You

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