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Psychiatric Disorders in Pregnancy

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Some of the key takeaways from the document are that mood disorders like depression and anxiety are among the most common psychiatric disorders during pregnancy. Major depression, dysthymia, and bipolar disorder are also discussed in detail. Risk factors for depression include stressful life events, family history, abuse or trauma exposure. Treatment options discussed include counseling, psychotherapy, and various psychotropic medications.

The document states that the most common psychiatric disorders in pregnancy are mood disorders (depression) and anxiety disorders. Depression, major depressive disorder, dysthymia, and bipolar disorder are specifically mentioned.

The document lists several risk factors for depression during pregnancy on pages 3 and 4, including stressful life events, recent death of a loved one, family history, history of abuse or trauma, exposure to traumatic events, intimate partner violence, serious or chronic medical conditions, alcohol or drug abuse, and prior episodes of depression.

PSYCHIATRIC DISORDERS IN

PREGNANCY
SHARON TREESA ANTONY 2ND YEAR M.SC
NURSING
Most common disorders
• Mood disorders ( Depression)

• Anxiety disorders
Depression
• Major depressive disorder
• Dysthymia
• Bipolardisorder
Depression: risk factors
• Stressful life events
• Recent death of a loved one
• Family history
• History of abuse or trauma
• Exposure to traumatic events
• Intimate partner violence
• A serious or chronic medical condition
• Alcohol or drug abuse
• Prior episodes of depression
Major depression: symptoms
• Depressed mood + anhedonia+ any 3 of the
following:
• Sleep disorders
• Interest deficit or lack of feeling pleasure
• Guilt
• Energy deficit
• Concentration deficit
• Appetite disorder
• Psychomotor retardation or agitation
• Suicidality
Dysthymia ( American Psychiatric
Association)
• Depressed mood for most of the day* 2years

• Presence of 2 or more of the symptoms listed

under major depression

• Never any mania/hypomania


Bipolar disorder

• MAJOR DEPRESSION+

• HISTORY OF MANIA OR

• HYPOMANIA
Symptoms of mania
• Inflated self esteem

• Decreased need for sleep

• Talkative

• Flight of ideas

• High energy or irritability


Symptoms of hypomania
• Lasts a minimum of 4 days

• Briefer duration

• Less severe symptoms


• Change in functioning

• Not severe to cause marked impairment in social


or occupational functioning

• No psychosis
Screening for depression
• Patient health questionnaire-2

• Patient health questionnaire-9

• Beck depression inventory

• The centre for epidemiologic studies- depression

scale
Treatment
• Cognitive behavioural therapy

• Counselling

• Faith based therapy

• Group therapy

• Psychotropic medications

• Yoga and acupuncture


Pharmacotherapy
• SSRI

• NDRI

• SNRI
• Fluoxetine :10-20mg

• Sertraline:m5omg

• Escitalopram:10mg

• Bupropion :200mg

• Venlafaxine:37.5mg
Teratogenicity
• Paroxetine:CVS malformations, persistent
pulmonary hypertension, VSD
• SSRI: VSD, right ventricular outfloew tract
lesions, preterm birth, Low birth weight, RDS
Nursing management
• Disturbed self esteem related to lack of positive
reinforcement of one’s values and worth
• Hopelessness r/t lack of energy to mobilize
resources
• Risk for fetal injury related to lack of interest in
self care
• Disturbed sleep pattern r/t internal stress

• Social isolation r/t inability to engage in

satisfying personal relationships

• Powerlessness related to lack of inability to exert

control
Mania
• Antipsychotics: EPS in neonates
• Lithium: CVS defects, neonatal cyanosis, lethargy,
flaccidity, and non toxic goiter: contraindicated for
1st 3 months
• Benzodiazepiines: oral clefts
• Carbamazepine and valproate: NTDs
• ECT: safest
Anxiety, stress and obsessive
compulsive disorder
Phobia
s• Cognitive behavioural therapy
• Hypnotherapy
• Antidepressants
• Beta blockers
• Benzodiazepines
Generalized anxiety disorder
• Excessive and uncontrollable anxiety and worry
about activities or events + 3 of the following:
• Restlessness
• Muscle tension
• Difficulty with concentration
• Sleep disturbance
• Fatigue
• Irritability
Treatment
• Antidepressants
Panic attack
• Unexpected or triggered period of intense
anxiety or fear
Symptoms
• Sweating
• Trembling or shaking
• Nausea
• Abdominal pain
• Chest discomfort/pain
• Dizziness
• Light headedness
• Unsteadiness
• Fainting
• Fear of losing control / dying
• parasthesias
Treatment
• SSRI
• Cognitive behavioural therapy
• Meditation
• Anti anxiety drugs
Screening
• GAD screening tool-7
• <5: mild
• 5-10: moderate
• 10 -15: severe
Risks of untreated depression and
anxiety during pregnancy
• Burden of disability

• Prematurity/IUGR

• Risk for postpartum depression/ postpartum

psychosis, postpartum OCD/ suicide or

infanticide
Substance dependence
Cocaine
• Effect on CNS

• Sudden vasoconstriction

• Increased RR,HR,BP
• Vasoconstriction: compromise placental

circulation, premature placental separation,

preterm labour and fetal death


Infants born to cocaine dependent
mother
• Intracranial hemorrhage

• Withdrawal syndrome
Diagnosis
• Urinalysis
Treatment
• Counselliing
Amphetamines
• High concentration in maternal circulation

• Newborn shows jitteriness and poor feeding at


birth, growth restriction
Marijuana and Hashish
• Tachycardia

• A sense of well being

• Excreted in breast milk

• Reduced milk production

• Loss of short term memory


Phencyclidin
e
• Crosses placenta
• Hallucinations
Narcotic agonists
• Euphoria followed by sedation
• Can result in PIH
• Withdrawal symptoms
Effects on infant
• Small for gestational age

• Fetal distress

• Meconium aspiration

• Withdrawal symptoms
Inhalants
• Cardiac irregularities
• Respiratory depression
• Limit fetal O2 supply
Alcohol
• Fetal alcohol syndrome
• Cognitive challenges
Nursing diagnoses
• Risk for injury to self and fetus r/t chronic
substance abuse
POSTPARTUM PSYCHIATRIC DISORDERS
Etiology
• Endocrinal changes

• Change in body image

• Activation of unconscious psychological conflicts

• Intrapsychic recognition of becoming a mother


Biological factors
• Genetic factors
• Endocrine
• Biochemical
• Sleep patterns
Psychological factors
• Psychodynamic explanations
• Personality factors
Social and interpersonal factors
• Society’s attitudes
• Husband’s support
• low social class
• Unmarried status
• Early sexual and marital problems
• Previous abortions
• Unstable, unsupportive husband
Type
s• Postpartum blues
• Postpartum psychoses
• Postpartum depression
Postnatal blues
• Transient state of mental illness occuring 3-10
days after birth
Symptoms
• Weepiness
• Mood lability
• Feeling overwhelmed
• Sadness
• Frustration
• Fatigue/exhaustion
• A negative feeling towards child
• Helplessness
• Insomnia
Treatment
• Psychological support
• Self limiting
• Her fear and anxiety is dealt with calm and quiet
approach
• Reassurance
• Family support
Postpartum depression
• It develops within 6 months of child birth.
5 of the symptoms* 2 weeks
• Depressed mood
• Significant change in weight
• Sleep disorders
• Psychomotor agitation or retardation
• Fatigue
• Inappropriate feelings of guilt or worthlessness
• Impaired concentration
• Recurrent suicidal thoughts
Strong Risk factors
• Anxiety during pregnancy
• Depression during pregnancy
• Stressful life events during pregnancy
• Low level of social support; single marital status
• History of depression
• Postpartum depression after a prior pregnancy
Additional risk factors
• Biologic vulnerability
• Family history
• Unplanned pregnancy
• Young maternal age
• Lower socioeconomic status
• History of interpersonal violence
• Thyroid dysfunction
Screening for postpartum depression
• The Edinburgh postnatal depression scale
>12: require evaluation and possible referral to a
mental health specialist
10-12: presence of symptoms of distress
Repeat test in 1-2 week
Consider referral
0-9: if symptoms persist for more tha 1-2 weeks,
further evaluation
Treatment
• Psychotherapy
• Pharmacotherapy
• SSRIs are 1st line drugs ( fluoxetine and
citalopram are safe for breast fed infants)
Early predictive signs of postnatal
depression
• No visitors, not sharing news about birth with
relatives
• Unsupportive family
• Maternal rejection or ambivalence to pregnancy,
child birth or newborn
• Aggressiveness to newborn
• Sleep disturbance or severe nightmares
• Lack of interest in newborn care
• Intense feelings of loss
• Extreme feelings of sadness, anxiety, guilt and
anger
Nursing diagnoses
• Ineffective individual coping r/t stress of child
birth, negative self concept
• Impaired social interaction r/t severe
depression
• Impaired family processes r/t post partum
psychosis
• Impaired parenting r/t postpartum blues
,feelings of inadequacy
• Risk for injury r/t postpartum psychosis
• Ineffective family coping r/t maternal
depression
Postpartum psychosis
• Develops within 1st month after delivery
Risk factors
• Primipara
• Women with underlying psychiatric disorders
Symptoms
• Auditory hallucinations
• Delusions
• Disorientation
• Strong feelings of anger towards self and baby
• Paranoidstrong obsessive reaction
• Unipolar or bipolar
Treatment
• Lithium
• ECT
• Support and guidance
• Reintroduce mother and baby as soon as
possible
• Hospitalization and supportive
psychotherapy
Post partum PTSD
Risk factors
• Childhood trauma
• Sexual abuse
• Depression
• PTSD preceding the pregnancy
• Depression , anxiety or a fear of child birth
• Lack of support from care providers or partner
Treatment
• Debriefing and counselling
• Cognitive behavioural therapy
• Eye movement desensitization and
reprocessing
THANK YOU

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