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    5 Gene Interaction

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    Prem Shukla
    This document provides an introduction to gene interaction and epistasis. It defines epistasis as when one gene suppresses the expression of another non-allelic gene. It provides examples of recessive and dominant epistasis. Recessive epistasis occurs when a homozygous recessive condition determines the phenotype regardless of other genes. Dominant epistasis occurs when a dominant gene suppresses expression of another gene. The document includes homework questions and references for further reading.

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    5 Gene Interaction

    Uploaded by

    Prem Shukla
    179 views9 pages
    This document provides an introduction to gene interaction and epistasis. It defines epistasis as when one gene suppresses the expression of another non-allelic gene. It provides examples of recessive and dominant epistasis. Recessive epistasis occurs when a homozygous recessive condition determines the phenotype regardless of other genes. Dominant epistasis occurs when a dominant gene suppresses expression of another gene. The document includes homework questions and references for further reading.

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    PPT 5 GENE INTERACTION

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    This document provides an introduction to gene interaction and epistasis. It defines epistasis as when one gene suppresses the expression of another non-allelic gene. It provides examples of recessive and dominant epistasis. Recessive epistasis occurs when a homozygous recessive condition determines the phenotype regardless of other genes. Dominant epistasis occurs when a dominant gene suppresses expression of another gene. The document includes homework questions and references for further reading.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    179 views9 pages

    5 Gene Interaction

    Uploaded by

    Prem Shukla
    This document provides an introduction to gene interaction and epistasis. It defines epistasis as when one gene suppresses the expression of another non-allelic gene. It provides examples of recessive and dominant epistasis. Recessive epistasis occurs when a homozygous recessive condition determines the phenotype regardless of other genes. Dominant epistasis occurs when a dominant gene suppresses expression of another gene. The document includes homework questions and references for further reading.

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    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    of 9

    UNIVERSITY INSTITUTE OF SCIENCES

    Academic Unit I
    Bachelor of Engineering (Computer Science & Engineering)
    Biology For Engineers 20SZ148

    INTRODUCTION DISCOVER . LEARN . EMPOWER


    By Shruti Sharma
    Gene Interaction
    • Mendelian genetics does not explain all kinds of inheritance for which the phenotypic ratios
    in some cases are different from Mendelian ratios (3:1 for monohybrid, 9:3:3:1 for di-hybrid
    in F2).

    • This is because sometimes a particular allele may be partially or equally dom­inant to the
    other or due to existence of more than two alleles or due to lethal alleles.

    • These kinds of genetic interactions between the alleles of a single gene are referred to as
    allelic or intra- allelic interactions.

    • Non-allelic or inter-allelic interactions also occur where the development of single


    character is due to two or more genes affecting the expression of each other in various ways.

    2
    Epistasis (Non-allelic or inter-allelic interactions)

    • When a gene or gene pair masks or prevents the expression of other non-
    allelic gene, called epistasis.
    • The gene which produces the effect called epistatic gene and the gene
    whose expres­sion is suppressed called hypostatic gene.

    • Recessive Epistasis or Supplementary Genes


    • Dominant Epistasis

    3
    Homozygous recessive condi­tion
    of a gene determines the
    phenotype irres­pective of the
    alleles of other gene pairs, i.e.,
    recessive allele hides the effect
    of the other gene. 

    Dominant gene C produces black


    colour, absence of it causes albino.

    Gene A pro­duces agouti colour in


    presence of C, but cannot express in
    absence of it (with cc) resulting in
    albino.

    Thus recessive allele c (cc) is epistatic


    to dominant allele A

    Recessive Epistasis in the coat color of mice. 4


    • Dominant gene C produces black colour, absence of it causes albino.
    • Gene A pro­duces agouti colour in presence of C, but cannot express with cc resulting in albino. Thus
    recessive allele c (cc) is epistatic to dominant allele A
    5
    Dominant Epistasis
    A dominant gene does not allow the
    expression of other non-allelic gene
    called dominant epistasis.

    In summer squash, the fruit colour is


    governed by two genes. The dominant
    gene W for white colour, suppresses the
    expres­sion of the gene G which controls
    yellow colour.
    So yellow colour appears only in
    absence of W. Thus W is epistatic to G.

    In absence of both W and G, green


    colour develops
    6
    HOME WORK

    Q 1. How are the alleles of a gene different from each other? What is its importance?

    Q2. Differentiate between dominance, co-dominance and incomplete dominance.

    Q3. In cucumbers, orange fruit color (R) is dominant over cream fruit color (r). A cucumber plant

    homozygous for orange fruits is crossed with a plant homozygous for cream fruits. The F1 are intercrossed

    to produce the F2.

    (a) Give the genotypes and phenotypes of the parents, the F1, and the F2.
    • Q4. Give the expected genotypic and phenotypic ratios for the following crosses for ABO blood types. (
    a) Iai x Ibi (b) IAIBx Iai (c) IAIB x IAIB (d) ii xIAi (e) IAIB x ii
    7
    REFERENCES

    • Gupta, P.K.. Cytology, Genetics and Molecular Biology, Rastogi Publishers, Meerut, 1993.
    • Roit I.M., Brostoff J. and Male D. Mosby .Immunology (6 th Edition) by, An imprint of Elsevier Sci Ltd.,
    2002.
    • https://nptel.ac.in/courses/121/106/121106008/
    • https://www.utoledo.edu/engineering/bioengineering/undergrad/prospective/whatisbioe.html#:~:text=Bioengi
    neering%20is%20the%20application%20of,health%20care%20and%20other%20fields.
    • https://i.pinimg.com/originals/68/c9/30/68c930e95113ceb2e3dfc9de2f164680.png
    • https://youtu.be/FBUpnG1G4yQ
    • https://www.genome.gov/about-genomics/fact-sheets/Genetic-Mapping-Fact-Sheet

    8/10
    THANK YOU

    For queries
    Email: pardeep.e12145@cumail.in

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