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    CLM Presentation

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    HSC UNITED
    1. Sickle cell anemia is a hereditary blood disorder where red blood cells become rigid and sticky and form into a sickle or crescent moon shape, which can cause pain and organ damage. 2. It is caused by a genetic defect that changes the shape of hemoglobin and red blood cells. There is no cure, but treatments can help manage pain and prevent complications. 3. Management involves medications, supplements, vaccines, transfusions or surgery depending on severity. Preventing transmission involves genetic counseling and testing partners for sickle cell trait before having children.

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    CLM Presentation

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    1. Sickle cell anemia is a hereditary blood disorder where red blood cells become rigid and sticky and form into a sickle or crescent moon shape, which can cause pain and organ damage. 2. It is caused by a genetic defect that changes the shape of hemoglobin and red blood cells. There is no cure, but treatments can help manage pain and prevent complications. 3. Management involves medications, supplements, vaccines, transfusions or surgery depending on severity. Preventing transmission involves genetic counseling and testing partners for sickle cell trait before having children.

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    1. Sickle cell anemia is a hereditary blood disorder where red blood cells become rigid and sticky and form into a sickle or crescent moon shape, which can cause pain and organ damage. 2. It is caused by a genetic defect that changes the shape of hemoglobin and red blood cells. There is no cure, but treatments can help manage pain and prevent complications. 3. Management involves medications, supplements, vaccines, transfusions or surgery depending on severity. Preventing transmission involves genetic counseling and testing partners for sickle cell trait before having children.

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    42 views13 pages

    CLM Presentation

    Uploaded by

    HSC UNITED
    1. Sickle cell anemia is a hereditary blood disorder where red blood cells become rigid and sticky and form into a sickle or crescent moon shape, which can cause pain and organ damage. 2. It is caused by a genetic defect that changes the shape of hemoglobin and red blood cells. There is no cure, but treatments can help manage pain and prevent complications. 3. Management involves medications, supplements, vaccines, transfusions or surgery depending on severity. Preventing transmission involves genetic counseling and testing partners for sickle cell trait before having children.

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    Harar Health Science College

    Assessment of MLS
    Group four
    Public Health

    Submit by Anumein
    Group Four
     Students Name..............ID...........
    1 Nejib Yusuf................0132/13
    2 Jibril Abdurahman.........0116/3
    3 Muaz Abdi..................0127/13
    4 Ana Mohamed...............0101/13
    5 Lina Mohamed..............1213/12
    6 Abrahim Ahmed............0099/12
    7 Saladin Abdusamed.......0135/13
    8 Alamudin Abdulaziz......0100/13
    9 Mohamed Siraj.........0120/13
    10 Abdi Ahmed...........0096/13
    11 Ziyad Abdi.............0347/13
    12 Ayub Baker.............0237/12
    13 Abdala Aliy..............0095/13
    • Sickle cell anemia is a disease where the body produces abnormal red
    blood cells looking like a crescent or sickle.

    The body produces normal red blood cells that are flexible and round and
    can easily move through the blood vessels.

    In sickle cell anemia, red blood cells become rigid and sticky and form like a
    sickle or crescent moon
     These irregularly shaped cells can get stuck in small blood vessels, which
    can slow or inhibit the flow of blood and oxygen to parts of the body.
     Red blood cells live for 120 days before the body needs to be replaced; but
    sickle cells usually die within 10 to 20 days, causing a red blood cell
    deficiency that leads to (anemia).
     Sickle cell anemia is a hereditary type that is transmitted by genes from
    parents to their children, that is, it is not contagious and cannot be picked
    up by a person(like: (cold or infection) to another.
    Causes:
     A defect in the gene responsible for the formation of hemoglobin in
    the body, which changes the shape of red blood cells to become
    inflexible and sticky.
     Symptoms:
     • Pale skin
     • Fatigue and exhaustion
     • Severe pains
     • Vision problems
     • painful swelling in feet and hands
     • chronic pain episodes
     • delayed growth
     • Repetitive bacterial infections.


     Diagnosis:
     Diagnosis is done by a doctor after studying the symptoms and
    pathological history of adults and children and conducting blood tests
    to examine hemoglobin. If the patient has the disease, the doctor may
    suggest additionaltests to check for possible complications.

    Complications:
    • brain stroke.
    • Acute chest syndrome that causes chest pain, fever and difficulty
    • Hypertension in the lungs (pulmonary hypertension).
    • Organ damage including kidney, liver and spleen.
    • Blindness.
    • Leg blisters.
    • Gallstones.
    • Sexual dysfunction.

     Treatment:
     There is no definitive cure; however, there are medications that can
    helpprevent problems associated with the disease.
     • Drugs to relieve the pain
     • Folic acid supplements to strengthen healthy blood cells.
     • Vaccination and antibiotics to prevent infection.
     • In severe cases the patient may need blood transfusion or surgery.
    Prevention:
    • Abidance by a comprehensive pre-marital medical examination helps toreduce
    intergenerational transmission of sickle cell disease.

     • If you are pregnant, you should see a genetic counselor before decidingto have
    children.

     If you have sickle cell anemia, you should:


     • Drink plenty of fluids and follow a healthy diet.


     • Avoid exposure to extreme cold or heat.


     • Avoid high places such as aircraft and others.


     • Make sure you have enough oxygen during exercising and when you are in the
    mountains.
    Frequently Asked Questions:
    1. What is the difference between sickle cell anemia and iron deficiency
    anemia?
    Sickle cell anemia breaks red blood cells, whereas in anemia, red blood cells
    are healthy; but their number is less than normal.

     2. Is there a difference between the carrier and the patient?


     Yes, sickle cell carriers are caused by inheriting one copy of the gene from a
    parent. Having Sickle cell disease is caused by inheriting the gene from both
    parents.

     3. Can a person develop from a sickle cell carrier to an infected person?


     No, a person cannot develop from a carrier to an infected person; but
    sicklecell carriers can pass the gene to their children.
    4. What precautions should a carrier take when exercising?
    They should take into account the same precautions that can prevent injuriesand
    diseases associated with exercise, including heat and moisture
     considerations, drinking adequate fluids, resting as needed, and not
    exceedingthe current level of fitness.
    Misconceptions:

     • There is a definitive treatment for sickle cell anemia.


     There is none; however, research is underway on bone marrow transplantation,
    gene therapy, and new medicines for sickle cell anemia.

     • Sickle cell anemia patients are recommended to use iron supplements.


     Iron supplements should not be used to treat sickle cell anemia without consulting
    your doctor as they may cause harm.

     • There is vaccination for the prevention of sickle cell anemia.


     There is none, because it is transmitted by the parents' genes.

     • Any sickle cell anemia carrier must refrain from marriage because ofthe risk of
    transmission to children
     It is possible for a carrier to marry a healthy person (not a carrier) and have
    healthy children.
    Thank You

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