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    Data Analysis in Preclinical Developement

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    Omkar Kale
    Computers play a significant role in preclinical drug development by helping with data analysis and acting as a storehouse for all information related to a drug, including safety, dosage, and interactions. They make the development process more efficient by aiding in toxicity studies, developing predictive models, and ensuring collection and management of clinical data. Key computer systems used include laboratory information management systems (LIMS) to manage laboratory workflow and data, and text information management systems (TIMS) to facilitate generation and management of text-based reports in a secure and efficient manner.

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    Data Analysis in Preclinical Developement

    Uploaded by

    Omkar Kale
    240 views26 pages
    Computers play a significant role in preclinical drug development by helping with data analysis and acting as a storehouse for all information related to a drug, including safety, dosage, and interactions. They make the development process more efficient by aiding in toxicity studies, developing predictive models, and ensuring collection and management of clinical data. Key computer systems used include laboratory information management systems (LIMS) to manage laboratory workflow and data, and text information management systems (TIMS) to facilitate generation and management of text-based reports in a secure and efficient manner.

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    Computers play a significant role in preclinical drug development by helping with data analysis and acting as a storehouse for all information related to a drug, including safety, dosage, and interactions. They make the development process more efficient by aiding in toxicity studies, developing predictive models, and ensuring collection and management of clinical data. Key computer systems used include laboratory information management systems (LIMS) to manage laboratory workflow and data, and text information management systems (TIMS) to facilitate generation and management of text-based reports in a secure and efficient manner.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    240 views26 pages

    Data Analysis in Preclinical Developement

    Uploaded by

    Omkar Kale
    Computers play a significant role in preclinical drug development by helping with data analysis and acting as a storehouse for all information related to a drug, including safety, dosage, and interactions. They make the development process more efficient by aiding in toxicity studies, developing predictive models, and ensuring collection and management of clinical data. Key computer systems used include laboratory information management systems (LIMS) to manage laboratory workflow and data, and text information management systems (TIMS) to facilitate generation and management of text-based reports in a secure and efficient manner.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    of 26

    Computers as Data Analysis

    in Preclinical Developement
    Chapter 6
    Computers play a significant role in preclinical
    development.
    Computers help a lot in data analysis.
    Preclinical Development refers to development of
    adequate data, facts and figures to ensure that a
    particular drug is safe for human use.
    Main purpose of preclinical studies is to determine
    first safe dose of upcoming drug or medicine for
    human use.
    Before any drug is tested on humans, a lot of
    experiments are conducted on animals to ensure that
    the treatment goes well as per expectation and
    outcome is generated.
    Only then drug is declared safe for human testing.
    All the data related to a drug, its existence, use, safety,
    dosage, outcome, interactions, pharmacological effect,
    preclinical effect, preclinical testing methods, FDA
    approval, safety measures, adverse effects, overdose etc
    are considered well before the launch .
    This crucial information is entered and stored in
    computers that can be further analyzed as and when
    required by scientists, pharmacists, physicians and
    other healthcare professionals.
    Role of Computers in Preclinical
    Development
    Act as a store house of Drug information
    Aids in study of toxicity and risk
    management
    Helps to develop predictive models for
    better decisions
    Makes pharmaceutical development more
    efficient
    Role of Computers in Preclinical
    Development
    Ensures collection and management
    of clinical data.
    Aids in better medical decision
    making.
    Improves quality of healthcare
    management.
    Uses of Computers in clinical Education
    Multimedia: it refers to present
    information in formats other than
    text only. E.g. Sounds, Images,
    Graphics, animations, Videos.
    Computers help in great deal in
    pharmacy training and education.
    Uses of Computers in clinical Education
    X- Rays, Electrocardiograms and other
    interpretations and values with reference to
    cases can be shown on multimedia and
    taught to the students.
    E- books, websites and wikipedia are also a
    great source of help for the clinical
    pharmacists and students to gather
    information and data.
    Uses of Computers in clinical Education
    Computer simulations are helpful
    in teaching techniques i.e
    Demonstration of complete
    physiological or pharmacological
    process.
    Chromatographic Data Analysis
    It refers to software that simplifies entire
    workflow process and saves a lot of time and
    energy.
    It gives better and faster results.
    This Software is used to collect and analyze
    Chromatographic Results i.e. techniques
    used to separate mixtures in a laboratory.
    Cont.
    Thus it is related to effective workflow
    within a laboratory.
    It also can refers to as a workstation
    that controls all the instruments
    present in a laboratory.
    It represents an integrated system with
    all the saved in a central server.
    CDS Products:
    Chromeleon 7.2 CDS Software: It is used to
    simplify lab workflow with unified control
    for effective data management.
    Laboratory Information management
    System: manages all workflow within a
    laboratory. It reduces implementation.
    Training and validation costs of an
    organization.
    CDS Products:
    Scientific Data Management System:
    SECURELY SHARES data across multiple
    users in an organization.
    Integrated solutions: Provides most
    effective lab data by integrating instruments
    and software.
    Importance of CDS
    It can judged from the fact that high
    performance liquid chromatography
    (HPLC) and Gas Chromatography play an
    important role in pharmaceutical analysis.
    Research and Development in
    Pharmaceutical companies is almost
    impossible without these two types of
    chromatography.
    LIMS
    Laboratory information management
    system : refers to a software based data
    management system that supports all
    modern laboratory operations. LIMS
    form an important part of data
    management systems used in
    preclinical development.
    LIMS
    LIMS were designed to automate major
    parts of development like sample
    tracking, sample distribution, work
    assignment, result capturing, data
    processing, data review, report
    generation, and data sharing.
    Thus LIMS fastened the process of
    management in preclinical development.
    Applications of LIMS
    Sample management
    Instrument and application
    Integration.
    Electronic Data Exchange.
    Report Generation.
    Inventory Management.
    Benefits of LIMS
    Thus, LIMS provides full
    application functionality through a
    web browser to ensure generation
    of reliable and accurate results with
    high speed and low maintenance
    costs.
    Benefits LIMS
    Fast reports
    Reduction in paper work
    Improved efficiency
    Improved data quality
    Reduced errors
    Avoids duplicacy
    Simple formulas for calculation
    Better integration with other departments
    TIMS
    Text Information Management System
    Refers to collection and management
    of text information from one or more
    sources that can be shared with
    different users at the right time and
    right place.
    TIMS
    Information is entered, processed and
    stored in the computer and later on,
    can be used as per requirement.
    The information can be stored in any
    format like images, Videos, audios,
    messages, texts, numbers etc.
    TIMS
    TIMS is a type of database
    management system which
    supports an access methods based
    on both Select and search query.
    It is mainly used by scientists a
    report template.
    Benefits of TIMS
    Saves time and energy.
    Faster method of report generation.
    Ensures accuracy.
    Improves efficiency in managing critical data.
    Reduces paper work
    Strict Security
    Smooth and Easy workflow.
    TIMS
    TIMS is one step towards
    encouraging the process of writing,
    reviewing, auditing, approving and
    publishing pharmaceutical text
    reports .
    Thank you

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