2- ONCOLOGY4
2- ONCOLOGY4
2- ONCOLOGY4
Prepared by
Abdelrady Mohamed elsayed
Mahmoud Reda Mahmoud
Under supervision
Prof.Dr- Zeinab Hussein Ali
Professor and Head of Adult Health
Nursing Department
Code of Conduct
objectives
At the end of this lecture the learner will
be able to:
1. Compare the function and behavior of
normal and cancer cells.
2. Differentiate between benign and
malignant tumors.
3. Identify agents and factors that have
been found to be carcinogenic.
4. Describe the role of nurses in health
education and prevention in decreasing
the incidence of cancer.
5. Differentiate among the goals of cancer
Cont. Objectives
8- Identify potential
complications for the
patient with cancer and
discuss associated nursing
care.
9- Identify assessment
parameters and nursing
INTRODUCTION
Cancer is a family of complex
diseases with manifestations that vary
according to the body system affected
and the type of tumor cells involved.
This disease can affect people of any
age, gender, ethnicity, or geographic
region. Although the incidence and
mortality rates of cancer have
continued to decline since 1990, it
remains one of the most feared
What Is Cancer?
neoplasms.
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Key Terms
Plasias" , refer to cancerous or pre-cancerous cells.
1. Hyperplasia is any abnormal multiplication of cells.
Hyperplasia refers to an abnormal increase in cellular
quantity (i.e., constantly dividing cells).
2. Metaplasia is the transformation of one type of tissue
into another.
Metaplasia ("change in form") refers to the exchanging
of one type of differentiated cell type for another mature
differentiated cell type.
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Key Terms
Dysplasia (from the Greek "malformation“. This
generally consists of an expansion of immature cells, with
a corresponding decrease in the number and location of
mature cells.
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The Four Major Categories of Cancer
• Carcinoma: Cancer arising from epithelial
tissue (for example, basal cell carcinoma)
• Sarcoma: Cancer arising from connective
tissue, muscle, or bone (for example,
osteosarcoma)
• Lymphoma: Cancer arising from lymphoid
tissue (for example, lymphoma)
• Leukemia: Cancer of the blood-forming cells
in the bone marrow (for example,acute
lymphocytic leukemia)
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Tumor
Benign Tumor
Tumor
Malignant
Tumor
(Cancer)
Classification of Cancer
According to Behavior of Tumor
Cells are undifferentiated and often bear little Well-differentiated cells that Cell
resemblance to the normal cells of the tissue resemble normal cells of the
from which they arose tissue from which the tumor characteristics
originated
Grows at the periphery and sends out Tumor grows by expansion Mode of growth
processes that and does not infiltrate
infiltrate and destroy the surrounding tissues the surrounding tissues;
usually encapsulated
Rate of growth is variable and depends on Rate of growth is usually Rate of growth
level of differentiation; the more anaplastic slow
the tumor, the faster its growth
Gains access to the blood and lymphatic Does not spread by Metastasis
channels metastasis
and metastasizes to other areas of the body 20
Invasion & Metastasis
2. CHEMICAL AGENTS
• Smoking is strongly associated
with cancers of the lung, head and
neck, esophagus, pancreas, cervix,
and bladder.
• Dietary ingredients
• Drugs
Etiology of cancer
4. Dietary Habits
Low-Fiber
High-fat
Processed foods
alcohol
Etiology of cancer
•
• The bacterium Helicobacter pylori
has been associated with an
increased incidence of gastric
malignancy,
• 6. Hormonal agents
disturbances in hormonal balance either
by the body’s own (endogenous)
hormone production or by
administration of exogenous hormones.
• 7. Immune Disease
• When the immune system fails to identify and stop
the growth of malignant cells, clinical cancer
develops.
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Etiology
36
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Risk Factors con.
3- Gender is a risk factor for certain types of cancer, rather
than for acquiring cancer in general (thyroid cancer occurs
more commonly among females, whereas bladder cancer is
seen more often among male patients).
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Clinical Manifestation
It is possible to present symptoms such as:
started (metastasized).
Clinical Manifestation
(gastrointestinal cancers)
• Direct Visualization:
– Sigmoidoscopy
– Cystoscopy
– Endoscopy
– Bronchoscopy
– Exploratory surgery; lymph
node biopsies to determine
metastases
Mammography
Begin annual mammography at age 40
• For women in their 20s and 30s, it is
recommended that CBE be part of a
periodic health examination, preferably
at least every 3 years.
• Asymptomatic women age 40 years and
over should continue to receive a CBE
as part of a periodic health
examination, preferably annually
Breast self exam
• Remember the alphabet A-B-C-D when assessing
skin lesions.
If the answer is yes to any questions listed here, it
could indicate a possible malignant lesion: .
• A—Is the lesion Asymmetrical in shape? .
• B—Are the Borders of the lesion irregular? .
• C—Are there different Colors within the lesion? .
• D—Is the Diameter of the lesion more than 5mm?
Which is a correct guideline for
performance of self breast exams (SBE) in
a 22year-old female client?
Staging:
a number (usually on a scale of 4) established by the
oncologist to describe the degree of invasion of the
body by the tumor.
Grading:
a number (usually on a scale of 3) established by a
pathologist to describe the degree of resemblance of the
tumor to the surrounding benign tissue.
Tumor Staging and Grading
• Staging: determines size of tumor, existence of
metastasis
– TNM
• T: size of primary tumor
• N: lymph node involvement
• M: degree of metastasis
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Chemotherapy
Systemic chemotherapy is the main treatment
available for disseminated malignant diseases.
Progress in chemotherapy resulted in cure for
several tumors.
Chemotherapy usually require multiple
cycles.
Chemotherapy: Treatment with drugs that kill
cancer cells or make them less active.
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Chemotherapy
The drugs used in cancer treatment vary in
their chemical structure , biological side
effects and toxicities. Some are effective in
treating one specific types of cancer while
others are utilized in the treatment of wide
variety of malignancies. The methods of
administration also vary according to the
chemotherapeutic and new techniques for
safer and more effective administration.
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There are different ways of chemotherapy may be
used:
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ROLE OF A NURSE
Prior to chemotherapy administration
Review- The chemotherapy drugs prescription which
should have
-Name of anti-neoplastic agent.
-Dosage -Route of administration.
-Date and time that each agent to be administered.
2. Accurately identify the client
3.Medications to be administered in conjunction with the
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ROLE OF A NURSE
Prior to chemotherapy administration
-Psychological status.
The following guidelines to be kept in mind:
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Alopecia..
Alopecia is descried as the loss of hair that
can occur with the radiation of the brain
Nursing Care
* Gently brush and comb, infrequently shampoo
* Avoid the use of hair coloring and chemical
* Give psychological support for change of body
image
* Give advice for using wig if necessary
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Skin Reactions
materials
* Open to fresh air but not direct to sunlight
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Nausea & Vomiting..
Nursing Care
* Eat small, frequent meals
* Eat salty foods, add salt in foods
• Drink clear or cool beverages
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How to take care the treated area?
and deodorant
Wear loose-fitting cloths
Shave with an electric razor only
Protect the skin from direct sunlight, and
extreme temperature
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Detection and Prevention of
Cancer
Primary and secondary prevention of cancer.
Primary prevention is concerned with reducing the
risks of cancer in healthy people.
Secondary prevention involves detection and
screening to achieve early diagnosis and prompt
intervention to halt the cancer process.
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PRIMARY PREVENTION
“The American Cancer Society public education program”
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SECONDARY PREVENTION
Detection efforts as suggested by the American Cancer Society
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Assessment:
BLEEDING.
SKIN PROBLEMS.
Alopecia (hair loss).
NUTRITIONAL CONCERNS.
PAIN.
FATIGUE.
PSYCHOSOCIAL STATUS.
BODY IMAGE
INFECTION 104
NURSING DIAGNOSES
Impaired oral mucous membrane
Impaired tissue integrity
Impaired tissue integrity: alopecia
Impaired tissue integrity: malignant skin lesions
Imbalanced nutrition, less than body requirements
Anorexia, Malabsorption, Cachexia
Chronic pain
Fatigue
Disturbed body image
Anticipatory grieving
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Nursing intervention
” Relieving pain“
Treat the risk factor or the cause
Give pain killer
Adjuvant medications are also administered to manage other
symptoms include : Antiemetic, antidepressants, antiseizure
agents, and corticosteroids.
Nonpharmacological such as relaxations, massage.
Be active listener
Nursing intervention
IMPROVING BODY IMAGE AND SELF-
ESTEEM:
Encourage independence and continued
participation in self-care and decision making.
Any negative feelings that the patient has or
threats to body image should be identified and
discussed.
The nurse serves as a listener and counselor to
both the patient and the family. 107
ASSISTING IN THE GRIEVING PROCESS:
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