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2006-2007 Meiosis & Sexual Reproduction
Cell division / Asexual reproduction Mitosis produce cells with same information identical daughter cells exact copies clones same number of chromosomes same genetic information Aaaargh! I ’ m seeing double!
Asexual reproduction Single-celled eukaryotes yeast Paramecium Amoeba Simple  multicellular  eukaryotes Hydra budding What are the disadvantages of asexual reproduction? What are the  advantages?
How about the rest of us? What if a complex multicellular organism (like us) wants to reproduce? joining of egg + sperm Do we make egg & sperm by mitosis? 46 46 + 92 egg sperm zygote What if we did, then…. Doesn’t work! No!   
Human female  karyotype 46 chromosomes 23 pairs XX diploid = 2 copies 2n
Human male  karyotype 46 chromosomes 23 pairs XY diploid = 2 copies 2n
How do we make sperm & eggs? Must reduce 46 chromosomes    23 must  half  the number of chromosomes haploid gametes egg sperm meiosis fertilization zygote 23 23 46 46 46 23 23
Meiosis makes sperm & eggs 46 chromosomes to 23 chromosomes half the number of chromosomes egg sperm meiosis haploid diploid 23 23 46 46
Paired chromosomes Homologous chromosomes both chromosomes of a pair carry “matching” genes  control same inherited characters homo logous  =  same   information diploid 2n 2n = 4 homologous chromosomes double stranded homologous chromosomes eye color (brown?) eye color (blue?)
Meiosis 1 overview 1st division of meiosis 4 chromosomes diploid 2n 2 chromosomes haploid 1n double stranded Copy DNA Line Up 1 Divide 1 gamete prophase 1 metaphase 1 telophase 1
2nd division of meiosis looks like mitosis Meiosis 2 overview 2 chromosomes haploid 1n gametes Line Up 2 Bye Bye 2 telophase 1 metaphase 2 telophase 2 4
Meiosis = reduction division Meiosis special cell division in sexually reproducing organisms reduce number of chromosomes 2n    1n  diploid    haploid  half makes  gametes   sperm, eggs
Meiosis & mitosis Meiosis to make gametes sperm & egg  Mitosis to make copies of cells growth repair development
Sexual reproduction lifecycle 1 copy haploid 1n 2 copies diploid 2n 1 copy haploid 1n meiosis fertilization We ’ re mixing things up here ! A good thing?
Putting it all together… meiosis    fertilization    mitosis + development mitosis zygote egg sperm meiosis fertilization mitosis & development gametes 23 23 46 46 46 23 23 46 46 46 46 46 46 46 46
The value of meiosis 1 Consistency over time meiosis keeps chromosome number same from generation to generation from Mom from Dad offspring Dad Mom
The value of meiosis 2 Change over time meiosis introduces genetic variation gametes of offspring do not have  same genes as gametes from parents new combinations of traits from Mom from Dad new gametes made by offspring offspring We ’ re mixing things up here ! variation
How does this explain: family resemblance & differences! Why are the kids so similar to    the parents but    not exact? Martin & Charlie Sheen, Emilio Estevez Michael & Kirk Douglas Baldwin brothers
Any Questions?? 2006-2007 What are the DIS advantages of asexual  reproduction? What are the DIS advantages of sexual  reproduction? What are the advantages of sexual  reproduction? What are the advantages of asexual  reproduction?

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25meiosis

  • 1. 2006-2007 Meiosis & Sexual Reproduction
  • 2. Cell division / Asexual reproduction Mitosis produce cells with same information identical daughter cells exact copies clones same number of chromosomes same genetic information Aaaargh! I ’ m seeing double!
  • 3. Asexual reproduction Single-celled eukaryotes yeast Paramecium Amoeba Simple multicellular eukaryotes Hydra budding What are the disadvantages of asexual reproduction? What are the advantages?
  • 4. How about the rest of us? What if a complex multicellular organism (like us) wants to reproduce? joining of egg + sperm Do we make egg & sperm by mitosis? 46 46 + 92 egg sperm zygote What if we did, then…. Doesn’t work! No!   
  • 5. Human female karyotype 46 chromosomes 23 pairs XX diploid = 2 copies 2n
  • 6. Human male karyotype 46 chromosomes 23 pairs XY diploid = 2 copies 2n
  • 7. How do we make sperm & eggs? Must reduce 46 chromosomes  23 must half the number of chromosomes haploid gametes egg sperm meiosis fertilization zygote 23 23 46 46 46 23 23
  • 8. Meiosis makes sperm & eggs 46 chromosomes to 23 chromosomes half the number of chromosomes egg sperm meiosis haploid diploid 23 23 46 46
  • 9. Paired chromosomes Homologous chromosomes both chromosomes of a pair carry “matching” genes control same inherited characters homo logous = same information diploid 2n 2n = 4 homologous chromosomes double stranded homologous chromosomes eye color (brown?) eye color (blue?)
  • 10. Meiosis 1 overview 1st division of meiosis 4 chromosomes diploid 2n 2 chromosomes haploid 1n double stranded Copy DNA Line Up 1 Divide 1 gamete prophase 1 metaphase 1 telophase 1
  • 11. 2nd division of meiosis looks like mitosis Meiosis 2 overview 2 chromosomes haploid 1n gametes Line Up 2 Bye Bye 2 telophase 1 metaphase 2 telophase 2 4
  • 12. Meiosis = reduction division Meiosis special cell division in sexually reproducing organisms reduce number of chromosomes 2n  1n diploid  haploid half makes gametes sperm, eggs
  • 13. Meiosis & mitosis Meiosis to make gametes sperm & egg Mitosis to make copies of cells growth repair development
  • 14. Sexual reproduction lifecycle 1 copy haploid 1n 2 copies diploid 2n 1 copy haploid 1n meiosis fertilization We ’ re mixing things up here ! A good thing?
  • 15. Putting it all together… meiosis  fertilization  mitosis + development mitosis zygote egg sperm meiosis fertilization mitosis & development gametes 23 23 46 46 46 23 23 46 46 46 46 46 46 46 46
  • 16. The value of meiosis 1 Consistency over time meiosis keeps chromosome number same from generation to generation from Mom from Dad offspring Dad Mom
  • 17. The value of meiosis 2 Change over time meiosis introduces genetic variation gametes of offspring do not have same genes as gametes from parents new combinations of traits from Mom from Dad new gametes made by offspring offspring We ’ re mixing things up here ! variation
  • 18. How does this explain: family resemblance & differences! Why are the kids so similar to the parents but not exact? Martin & Charlie Sheen, Emilio Estevez Michael & Kirk Douglas Baldwin brothers
  • 19. Any Questions?? 2006-2007 What are the DIS advantages of asexual reproduction? What are the DIS advantages of sexual reproduction? What are the advantages of sexual reproduction? What are the advantages of asexual reproduction?

Editor's Notes

  1. Consider the greater variation with 23 pairs of chromosomes = mixing and matching
  2. Consider the greater variation with 23 pairs of chromosomes = mixing and matching