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INTERNAL STRUCTURE
OF SPINAL CORD
Iram Anwar
Anatomyofspinalcord
Gross Appearance
 Cylindrical in shape
 Foramen magnum  L1/L2 (adult)
 L3 (newborn)
 Occupies upper ⅔ of vertebral canal
 Surrounded by 3 layers of meniges :
 dura mater
 arachnoid mater
 pia mater
 CSF in subarachnoid space
 Enlargements: cervical & lumbar
 Conus medullaris
 Filum termniale
 Anterior median fissure
 Posterior median sulcus
 31 pairs of spinal nerves attached to it
by the anterior roots & posterior roots
Anatomyofspinalcord
Gray Matter
 H-shaped pillar with anterior & posterior gray horns
 United by gray commissure containing the central canal
 Lateral gray column (horn) present in thoracic & upper
lumbar segments
 Amount of gray matter related to the amount of muscle
innervated
 Consists of nerve cells, neuroglia, blood vessels
Nerve cells in the anterior gray columns
 Large & multipolar
 Axons pass out in the anterior nerve roots as α-efferents
 Smaller nerve cells are multipolar
 Axons pass out in anterior roots as ɣ-efferents
Nerve cells in the posterior gray columns
 4 nerve cell groups
 Substantia gelatinosa
 situated at the apex
 throughout the length of spinal cord
 composed mainly of Golgi Type II neurons
 Nucleus proprius
 anterior to substantia gelatinosa
 present throughout the whole length of spinal cord
 main bulk of cells in posterior gray column
 Nucleus dorsalis (Clark’s column)
 base of posterior column
 C8 – L3 / L4
 associated with proprioceptive endings (neuromuscular spindles & tendon
spindles)
 Visceral afferent nucleus
 lateral to nucleus dorsalis
 T1 – L3
 receives visceral afferent info
 Nerve cells in the lateral gray columns
 Formed by the intermediolateral group of cells
 T1 – L2 / L3
 Cells give rise to preganglionic sympathetic fibres
 In S2, S3, S4; they give rise to preganglionic parasympathetic fibres
 The gray commissure & central canal
 connects the gray on each side
 central canal in the centre
 posterior gray commissure
 anterior gray commissure
 central canal present throughout
 superiorly continuous with the central canal of medulla oblongata
 inferiorly, expands as terminal ventricle
 terminates within the root of filum terminale
White Matter
 Divided into
 anterior white column
 lateral white column
 posterior white column
 Consists of nerve fibres, neuroglia, blood vessels
 White due to myelinated fibres
TRACTS
 Ascending
 Descending
 Intersegmental
Ascending Tracts
 Fibres that ascend from spinal cord to higher centres
 Conduct afferent information which may or may not reach
consciousness
 Information may be
 exteroceptive (pain, Tº, touch)
Lateral spinothalamic tract
 Pain & temp pathways
 1st-order neurons
 Pain conducted by δ A-type fibres & C-type fibres
 2nd-order neurons
 decussate to the opposite side
 3rd-order neurons
 ends in sensory area in postcentral gyrus
Anterior spinothalamic tracts
 Light (crude) touch & pressure pathways
Posterior spinocerebellar tract
 Muscle joint sense pathways to cerebellum
 Unconscious proprioception
 Muscle joint info from muscle spindles, GTO, joint receptors of the trunk
& lower limbs
 Info is used by the cerebellum in the coordination of movements &
maintenance of posture
Anterior spinocerebellar tract
 Majority of 2nd-order neurons cross to the opposite side
 Enter cerebellum through superior cerebellar peduncle
 Info from trunk, upper & lower limbs
 Also carries info from skin & subcut tissue
Descending Tracts
 Lower motor neurons
 Upper motor neurons
 Corticospinal tracts
 concerned with voluntary, discrete, skilled movements
Meninges
 Dura mater
 Arachnoid mater
 Pia mater
Anatomyofspinalcord
Dura mater
 Dense, strong fibrous membrane
 Encloses the spinal cord & cauda equina
 Separated from wall of vertebral canal by the extradural space
Arachnoid mater
 Delicate impermeable membrane
 Lies between pia and dura mater
 Separated from pia mater by subarachnoid space
Pia mater
 Vascular membrane
 Closely covers spinal cord
 Thickened on either side between nerve roots to form the
ligamentum denticulatum

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Anatomyofspinalcord

  • 3. Gross Appearance  Cylindrical in shape  Foramen magnum  L1/L2 (adult)  L3 (newborn)  Occupies upper ⅔ of vertebral canal  Surrounded by 3 layers of meniges :  dura mater  arachnoid mater  pia mater  CSF in subarachnoid space
  • 4.  Enlargements: cervical & lumbar  Conus medullaris  Filum termniale  Anterior median fissure  Posterior median sulcus  31 pairs of spinal nerves attached to it by the anterior roots & posterior roots
  • 6. Gray Matter  H-shaped pillar with anterior & posterior gray horns  United by gray commissure containing the central canal  Lateral gray column (horn) present in thoracic & upper lumbar segments  Amount of gray matter related to the amount of muscle innervated  Consists of nerve cells, neuroglia, blood vessels Nerve cells in the anterior gray columns  Large & multipolar  Axons pass out in the anterior nerve roots as α-efferents  Smaller nerve cells are multipolar  Axons pass out in anterior roots as ɣ-efferents
  • 7. Nerve cells in the posterior gray columns  4 nerve cell groups  Substantia gelatinosa  situated at the apex  throughout the length of spinal cord  composed mainly of Golgi Type II neurons  Nucleus proprius  anterior to substantia gelatinosa  present throughout the whole length of spinal cord  main bulk of cells in posterior gray column
  • 8.  Nucleus dorsalis (Clark’s column)  base of posterior column  C8 – L3 / L4  associated with proprioceptive endings (neuromuscular spindles & tendon spindles)  Visceral afferent nucleus  lateral to nucleus dorsalis  T1 – L3  receives visceral afferent info
  • 9.  Nerve cells in the lateral gray columns  Formed by the intermediolateral group of cells  T1 – L2 / L3  Cells give rise to preganglionic sympathetic fibres  In S2, S3, S4; they give rise to preganglionic parasympathetic fibres  The gray commissure & central canal  connects the gray on each side  central canal in the centre  posterior gray commissure  anterior gray commissure  central canal present throughout  superiorly continuous with the central canal of medulla oblongata  inferiorly, expands as terminal ventricle  terminates within the root of filum terminale
  • 10. White Matter  Divided into  anterior white column  lateral white column  posterior white column  Consists of nerve fibres, neuroglia, blood vessels  White due to myelinated fibres TRACTS  Ascending  Descending  Intersegmental
  • 11. Ascending Tracts  Fibres that ascend from spinal cord to higher centres  Conduct afferent information which may or may not reach consciousness  Information may be  exteroceptive (pain, Tº, touch) Lateral spinothalamic tract  Pain & temp pathways  1st-order neurons  Pain conducted by δ A-type fibres & C-type fibres  2nd-order neurons  decussate to the opposite side  3rd-order neurons  ends in sensory area in postcentral gyrus Anterior spinothalamic tracts  Light (crude) touch & pressure pathways
  • 12. Posterior spinocerebellar tract  Muscle joint sense pathways to cerebellum  Unconscious proprioception  Muscle joint info from muscle spindles, GTO, joint receptors of the trunk & lower limbs  Info is used by the cerebellum in the coordination of movements & maintenance of posture Anterior spinocerebellar tract  Majority of 2nd-order neurons cross to the opposite side  Enter cerebellum through superior cerebellar peduncle  Info from trunk, upper & lower limbs  Also carries info from skin & subcut tissue
  • 13. Descending Tracts  Lower motor neurons  Upper motor neurons  Corticospinal tracts  concerned with voluntary, discrete, skilled movements Meninges  Dura mater  Arachnoid mater  Pia mater
  • 15. Dura mater  Dense, strong fibrous membrane  Encloses the spinal cord & cauda equina  Separated from wall of vertebral canal by the extradural space Arachnoid mater  Delicate impermeable membrane  Lies between pia and dura mater  Separated from pia mater by subarachnoid space Pia mater  Vascular membrane  Closely covers spinal cord  Thickened on either side between nerve roots to form the ligamentum denticulatum