A 38-year-old female was admitted with worsening cough, shortness of breath, and chest pain. Laboratory tests revealed elevated inflammatory markers and sputum culture grew Klebsiella pneumoniae resistant to several antibiotics. She was started on meropenem and levofloxacin to treat the multi-drug resistant pneumonia. The pharmacist recommended adding levofloxacin due to resistance of the pathogen to standard antibiotics for community-acquired pneumonia.
2. GROUP MEMBER ID
Jenet binyam .................................
Jenifer apet .................................... RU 5164/12
Jiregna hailu................................... RU 1168/12
kalid ahmed.................................... RU 1467/12
3. OUTLINE
• Case identification
• Subjective findings
• Objective findings
• Physician’s assessment
• Medications given
• Pharmacists Assessment
• Drug therapy problem identified
• pharmaceutical care plan and follow up
• Patient education
• References
5. Subjective findings
• C/C: Worsing of cough with blood sputum,SoB
• HPI :This is a 38 years old female patient admitted
for the above Dx after she presented with worsing
of cough and Sob of 1 week duration with chest
pain of 2 week duration she has also hemipetesis
which is bright red in clour 2 weeks duration the
cough was productive with whitish sputum for past
1 year
• associated with HGIF, whight loss and night sweet
for the same duration. She has also 2 episode of
vomiting and diharria .
6. • she has no other chronic illness like
HTN,DM…
• No Hx of smoking
• No Hx ABM or LOC
• No HX of ortopena or PND
• No Hx of GBS
• No Hx of previous TB treatment
• No Hx of known medical illness
7. P/E:
• G/A :Acute sick looking
• V/S: BP;-110/70 PR;112 RR;48 T;38.1 SPO2:91% With
INo2 5L/M
• HEENT : PC,NIS
• LGS:NSLAP
• Chest : diffused crepitation all over the lung field ,and
left inter scapular area
• CVS;S1 and S2 well heard no murmur no gallop
• Abd: flat moves with respiration
no mass, no organomegaly
• CVS:NCVAT
• MSS/IS:no edema
8. date Time PR RR BP TO
SPO2
20/04/1
6
10:30a
m
98 36 118/76 37.5 94%INO2
21/4/16 12:30a
m
118 32 121/70 37.3 94% off
INO2
22/4/16 1:00am 108 30 120/85 37.5 93%INO2
22/4/16 3:30pm 120 38 115/80 37.2 88%INO2
23/4/16 6:00am 130 30 112/86 37.9 91%INO2
16. Pharmacist’s assessment
Past medical history
No PMH
Past medication history
No Past medications history
Drug allergy
NKDA
Family History
No family hx of the same illness
Substance use
No
Vaccination Hx
unknown
16
18. Pharmaceutical care plan and follow up
Medical
condition
DTP
identified
Goal of
therapy
Intervention Status of
intervention
Paramet
ers to be
monitor
ed
Severe
community
acquired
pneumonia
Need
additional
drug
To treat multiple
drug resistance
klebsiella
pneumonia
To start
levofloxacin 750
mg IV daily
pending • Sputem
cultur
Serum
electrol
yte
clinical
assesse
ment
18
19. Evidence for intervention
• In patient who infected with gram negative pathogen
not covered by standard CAP regimen
• include combination therapy with an antipseudomonal
carbapenam /antipnemococcal beta lactam antibiotics
and antipsedomonal fluroquinolone