The document summarizes key aspects of human digestion. It begins with an overview of nutrition and the two main parts - ingestion and digestion. It then describes the major components of the human digestive system from mouth to anus. Key functions and processes at each stage are highlighted, including mechanical and chemical breakdown of food. Absorption of nutrients primarily occurs in the small intestine. Undigested material then passes to the large intestine where water is absorbed before waste is excreted.
2. Nutrition
Process by which organisms obtain and utilize their food.
There are two parts to Nutrition:
1. Ingestion- process of taking food into the
digestive system so that it may be
hydrolized or digested.
2. Digestion- the breakdown of food (either
chemically or mechanically) in order to
utilize nutrients
3. Types of Nutrients
• Micronutrients- vitamins, minerals, & water
• Macronutrients- proteins, lipids,
carbohydrates, etc…
9. Swallowing (& not choking)
• Epiglottis
– flap of cartilage
– closes trachea (windpipe) when swallowing
– food travels down esophagus
• Peristalsis
– involuntary muscle contractions to move food along
10. Which type of digestion is the
following?
1. Chewing a saltine? -
2. Saliva breaking the saltine down into molecules of
glucose? -
3. Your tongue breaking pieces of a hamburger apart?
4. Pepsin (an enzyme) in your stomach breaking the
hamburger into amino acids?
11. Pharynx
• The back of the
throat.
• Larynx-
passage for air,
closes when we
swallow.
• Is approximately
15cm long.
12. Digestive Glands
• Groups of
specialized
secretory
cells.
• Found in the
lining of the
alimentary
canal or
accessory
organs.
13. • series of involuntary
wave-like muscle
contractions which
move food along the
digestive tract
Peristalsis
14. Stomach
• Food is temporarily
stored here.
• Gastric juices are
secreted.
• Has layers of
muscle that line the
inside.
• Mechanically and
chemically breaks
down food.
15. Stomach
• Functions
– food storage
• can stretch to fit ~2L food
– disinfect food
• HCl = pH 2
– kills bacteria
– chemical digestion
• pepsin
– enzyme breaks down proteins
But the stomach is made out of protein!
What stops the stomach from digesting itself?
mucus secreted by stomach cells protects
stomach lining
17. Gastric Juices
• Secreted by the
stomach.
• Acidic (pH 1.5-2.5)
(HCl).
• Pepsin- an enzyme that
breaks down large
proteins into amino
acids.
• Food is further broken
down into a thin liquid
called chyme.
20. Gall bladder
• Pouch structure located near the liver
which concentrates and stores bile
• Bile duct – a long tube that carries BILE.
The top half of the common bile duct is
associated with the liver, while the bottom
half of the common bile duct is associated
with the pancreas, through which it passes
on its way to the intestine.
21. BILE
• Bile emulsifies lipids (physically breaks
apart FATS)
• Bile is a bitter, greenish-yellow alkaline
fluid, stored in the gallbladder between
meals and upon eating is discharged into
the duodenum where it aids the process of
digestion.
22. Pancreas
• An organ which secretes both digestive
enzymes (exocrine) and hormones (endocrine)
• ** Pancreatic juice digests all major nutrient
types.
• Nearly all digestion occurs in the small intestine
& all digestion is completed in the SI.
25. Liver
• Function
– produces bile
• bile stored in gallbladder until needed
• breaks up fats
– act like detergents to break up fats
bile contains
colors from old
red blood cells
collected in liver =
iron in RBC rusts &
makes feces brown
bile contains
colors from old
red blood cells
collected in liver =
iron in RBC rusts &
makes feces brown
26. pancreas
produces enzymes to
digest proteins & starch
stomach
kills germs
break up food
digest proteins
store food
mouth
break up food
digest starch
kill germs
moisten food
liver
produces bile
- stored in gall bladder
break up fats
27. Small Intestine
• Most chemical
digestion takes place
here.
• Simple sugars and
proteins are absorbed
into the inner lining.
• Fatty acids and
glycerol go to lymphatic
system.
• Lined with villi, which
increase surface area for
absorption, one cell
thick.
28. Small intestine
• Function
– chemical digestion
• major organ of digestion & absorption
– absorption through lining
• over 6 meters!
• small intestine has huge surface area = 300m2
(~size of tennis court)
• Structure
– 3 sections
• duodenum = most digestion
• jejunum = absorption of nutrients & water
• ileum = absorption of nutrients & water
29. Duodenum
• 1st section of small intestines
– acid food from stomach
– mixes with digestive juices from:
pancreas
liver
gall
bladder
30. stomach
kills germs
break up food
digest proteins
store food
mouth
break up food
digest starch
kill germs
moisten food
pancreas
produces enzymes to
digest proteins & starch
31. Absorption in the SI
• Much absorption is thought to occur directly through the wall
without the need for special adaptations
• Almost 90% of our daily fluid intake is absorbed in the small
intestine.
• Villi - increase the surface area of the small intestines, thus
providing better absorption of materials
32. Absorption by Small Intestines
• Absorption through villi & microvilli
– finger-like projections
– increase surface area for absorption
34. Large intestines
(colon)
• Function
– re-absorb water
• use ~9 liters of water every
day in digestive juices
• > 90% of water reabsorbed
– not enough water absorbed
» diarrhea
– too much water absorbed
» constipation
35. Large Intestine
• Solid materials pass
through the large
intestine.
• These are undigestible
solids (fibers).
• Water is absorbed.
• Vitamins K and B are
reabsorbed with the
water.
• Rectum- solid wastes
exit the body.
36. You’ve got company!
• Living in the large intestine is a
community of helpful bacteria
– Escherichia coli (E. coli)
• produce vitamins
– vitamin K; B vitamins
• generate gases
– by-product of bacterial metabolism
– methane, hydrogen sulfide
38. Rectum
• Last section of colon
(large intestines)
– eliminate feces
• undigested materials
– extracellular waste
» mainly cellulose
from plants
» roughage or fiber
– masses of bacteria
39. Digestive Homeostasis Disorders
• ULCERS – erosion of the surface of
the alimentary canal generally
associated with some kind of irritant
40. • CONSTIPATIONCONSTIPATION – a
condition in which the
large intestine is
emptied with difficulty.
• Too much water is
reabsorbed
• and the solid waste
hardens
Digestive Homeostasis Disorders
41. Digestive Homeostasis
Disorders
• DIARRHEA – a gastrointestinal
disturbance characterized by
decreased water absorption and
increased peristaltic activity of
the large intestine.
• This results in increased,
multiple, watery feces.
• This condition may result in
severe dehydration, especially in
infants
43. Digestive Homeostasis
Disorders
• GALLSTONES – an accumulation of
hardened cholesterol and/or calcium
deposits in the gallbladder
• Can either be “passed” (OUCH!!) or
surgically removed
44. Digestive Homeostasis
Disorders
• ANOREXIA NERVOSA - a psychological
condition where an individual thinks they
appear overweight and refuses to eat.
• Weighs 85% or less than what is
developmentally expected for age and
height
• Young girls do not begin to menstruate at
the appropriate age.
After chewing and swallowing, it takes 5 to 10 seconds for food to pass down the esophagus to the stomach, where it spends 2 to 6 hours being partially digested.
Final digestion and nutrient absorption occur in the small intestine over a period of 5 to 6 hours.
In 12 to 24 hours, any undigested material passes through the large intestine, and feces are expelled through the anus.
Still, the epithelium is continually eroded, and the epithelium is completely replaced by mitosis every three days.
Gastric ulcers, lesions in the stomach lining, are caused by the acid-tolerant bacterium Heliobacter pylori.
Ulcers are often treated with antibiotics.
Pepsin is secreted in an inactive form, called pepsinogen by specialized chief cells in gastric pits.
Parietal cells, also in the pits, secrete hydrochloric acid which converts pepsinogen to the active pepsin only when both reach the lumen of the stomach, minimizing self-digestion.
Also, in a positive-feedback system, activated pepsin can activate more pepsinogen molecules.
About every 20 seconds, the stomach contents are mixed by the churning action of smooth muscles.
As a result of mixing and enzyme action, what begins in the stomach as a recently swallowed meal becomes a nutrient-rich broth known as acid chyme.
At the opening from the stomach to the small intestine is the pyloric sphincter, which helps regulate the passage of chyme into the intestine.
A squirt at a time, it takes about 2 to 6 hours after a meal for the stomach to empty.