Symptomatic presence of micro-organisms within the urinary tract i.e., kidney, ureters, bladder and urethra.
• Associated with inflammation of urinary tract.
2. CONTENT
• Introduction
• Classification of UTI
• Etiology & Risk factors
• Pathophysiology
• Clinical manifestation
• Diagnosis
• Medical management
• Conclusion
3. INTRODUCTION
Symptomatic presence of micro-
organisms within the urinary tract i.e.,
kidney, ureters, bladder and urethra.
• Associated with inflammation of
urinary tract.
4. Significant bacteriuria
Asymptomatic bacteriuria : bacteriuria with no
symptoms.
• Urethritis: infection of anterior urethral tract -
dysuria, urgency and frequency of urination.
• Cystitis: infection to urinary bladder -dysuria,
frequency and urgency, pyuria and haematuria.
5. • Acute pyelonephritis: infection of
one/both kidneys; sometimes lower tract
also-pyuria, fever, painful micturition
• Chronic pyelonephritis: particular
type of pathology of kidney; may/may
not be due to infection.
7. Etiology and risk factors
• Urethra-verticular reflux(from urethra to bladder)
• Uretero-vesical or vesico-urethral reflux-flowing urine
from the bladder and into one or both ureters.
• Feceal contamination of urethral meatus.
• Sexual intercourse
• Instrumentation of urinary tract
• Stasis of urine
• Obstruction of urinary flow.
• Prevalence is 8 times higher in the females then males.
8. Pathophysiology
• 4 routes of bacterial entry to urinary
tract.
1) Ascending infection
2) Blood borne spread
3) Lymphatogenous spread
4) Direct extension from other organs
11. • Pelvic inflammatory
diseases
• Genito-urinary tract
fistulas
• Men- through rectal
and colonic lymphatic
vessels to prostrate
and bladder.
• Women- through
periuterine lymphatics
to urinary tract.
Lymphatogenous
spread:
Direct extension
from other organs:
12. LOWER URINARY TRACT INFECTION
(CYSTITIS)
• Frequent pain and burning on urination.
• Spasms in the region of bladder and
suprapubic area.
• Hematuria and back pain.
CLINICAL MANIFESTATIONS OF URINARY
TRACT INFECTION
13. UPPER URINARY TRACT INFECTION
(PYELONEPHRITIS)
• Fever, chills, flank pain, painful
urination, pain and tenderness in the
area of costovertebrae (CVA).
• Renal failure at late stage can occur,
sign and symptoms can be –nausea,
vomiting, pruritus, weight loss, edema,
fatigue.
14. SIGN AND SYMPTOMS-
Urgency, frequency, burning, pain on urination, nocturia.
Pain and spasms in the region of bladder.
Pyuria (WBC in urine).
Haematuria, bacterial colony count increases.
15. DIAGNOSTIC TESTS OF URINARY TRACT
INFECTION
Colony-count – at least 1,00,000 colonies per millilitre of urine on
clean catch urine.
Cellular finding, microscopic hematuria, WBC increased
Urine culture, E.coli.
Test for sexually transmitted disease.
Other tests- intravenous urogram (IVU), intravenous pyelography
(IVP), ultrasound.
Cystitis (LUTI) - inflammation of urinary bladder and most often
caused by ascending infection from the urethra occurs more in
women.
16. UTI - MANAGEMENT
• Symptomatic UTI- antibiotic therapy
• Asymptomatic UTI- no treatment required
except in special situations.
• Non- specific therapy:
more water intake.
Maintaining acidity of urine by fluids like
canberry juice.
17. ANTI-MICROBIAL THERAPY
Goals of therapy:
• Elimination of infection
• Relief of acute symptoms
• Prevention of recurrence and long
Antibacterial agents- common medicines
include ampicillin, trimethoprim.
18. CONCLUSION
• Urinary tract infections are the 2nd most common
bacterial infections.
• Women are the most infected subjects in the
population.
• Development of resistance to antibiotics by the
bacteria result in problems during the treatment
and lead to relapse or recurrence.
• Recent advances such as development of
immunologicals like intranasal vaccines may result
in life time cure of the infection in future.
19. NURSING CONSIDERATION
Reducing pain- antimicrobial therapy, antispasmodics, hot tube
bath.
Maintain adequate elimination pattern is encourage lot of fluids,
avoid the cause.
Give knowledge- perineal hygiene, void every 2-3 hours/day, if
cause is sexual intercourse void immediately and take anti-
microbial, avoid indwelling catheter.
Assess vital signs.