Phosphodiesterase 2A (Q21105011)

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mammalian protein found in Homo sapiens
  • cGMP-stimulated phosphodiesterase 4
  • cGSPDE
  • cGMP-stimulated phosphodiesterase 1
  • cyclic GMP-stimulated phosphodiesterase
  • cGMP-stimulated phosphodiesterase 2
  • CGS-PDE
  • PDE2A
  • cGMP-dependent 3',5'-cyclic phosphodiesterase
  • phosphodiesterase 2A, cGMP-stimulated
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Language Label Description Also known as
English
Phosphodiesterase 2A
mammalian protein found in Homo sapiens
  • cGMP-stimulated phosphodiesterase 4
  • cGSPDE
  • cGMP-stimulated phosphodiesterase 1
  • cyclic GMP-stimulated phosphodiesterase
  • cGMP-stimulated phosphodiesterase 2
  • CGS-PDE
  • PDE2A
  • cGMP-dependent 3',5'-cyclic phosphodiesterase
  • phosphodiesterase 2A, cGMP-stimulated

Statements

molecular function
cGMP binding
determination method or standard
IDA
IEA
IMP
5 references
retrieved
21 June 2018
stated in
Structural determinants for inhibitor specificity and selectivity in PDE2A using the wheat germ in vitro translation system
GOA
curator
UniProt
UniProt protein ID
O00408
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00408&geneProductId=UniProtKB:O00408
determination method or standard
IMP
retrieved
21 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O00408
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00408&geneProductId=UniProtKB:O00408
determination method or standard
IEA
retrieved
21 June 2018
stated in
Phosphodiesterase 2A forms a complex with the co-chaperone XAP2 and regulates nuclear translocation of the aryl hydrocarbon receptor
GOA
curator
UniProt
UniProt protein ID
O00408
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00408&geneProductId=UniProtKB:O00408
determination method or standard
IDA
retrieved
21 June 2018
stated in
Mechanism for the allosteric regulation of phosphodiesterase 2A deduced from the X-ray structure of a near full-length construct
GOA
curator
UniProt
UniProt protein ID
O00408
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00408&geneProductId=UniProtKB:O00408
determination method or standard
IDA
retrieved
21 June 2018
stated in
Binding of cyclic nucleotides to phosphodiesterase 10A and 11A GAF domains does not stimulate catalytic activity
GOA
curator
UniProt
UniProt protein ID
O00408
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00408&geneProductId=UniProtKB:O00408
determination method or standard
IDA
cGMP binding
determination method or standard
IBA
IDA
IEA
IMP
6 references
retrieved
8 April 2019
stated in
Structural determinants for inhibitor specificity and selectivity in PDE2A using the wheat germ in vitro translation system
GOA
curator
UniProt
UniProt protein ID
O00408
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00408
determination method or standard
IMP
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O00408
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00408
determination method or standard
IEA
retrieved
8 April 2019
stated in
Binding of cyclic nucleotides to phosphodiesterase 10A and 11A GAF domains does not stimulate catalytic activity
GOA
curator
UniProt
UniProt protein ID
O00408
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00408
determination method or standard
IDA
retrieved
8 April 2019
stated in
Mechanism for the allosteric regulation of phosphodiesterase 2A deduced from the X-ray structure of a near full-length construct
GOA
curator
UniProt
UniProt protein ID
O00408
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00408
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phosphodiesterase 2A forms a complex with the co-chaperone XAP2 and regulates nuclear translocation of the aryl hydrocarbon receptor
GOA
curator
UniProt
UniProt protein ID
O00408
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00408
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00408
determination method or standard
IBA
cell component
biological process
cAMP catabolic process
determination method or standard
IDA
IMP
4 references
retrieved
27 February 2018
stated in
Iloprost- and isoproterenol-induced increases in cAMP are regulated by different phosphodiesterases in erythrocytes of both rabbits and humans
GOA
curator
UniProt
UniProt protein ID
O00408
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00408&geneProductId=UniProtKB:O00408
determination method or standard
IMP
retrieved
27 February 2018
stated in
Structural determinants for inhibitor specificity and selectivity in PDE2A using the wheat germ in vitro translation system
GOA
curator
UniProt
UniProt protein ID
O00408
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00408&geneProductId=UniProtKB:O00408
determination method or standard
IDA
retrieved
27 February 2018
stated in
Differential regulation of endothelial cell permeability by cGMP via phosphodiesterases 2 and 3
GOA
curator
UniProt
UniProt protein ID
O00408
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00408&geneProductId=UniProtKB:O00408
determination method or standard
IDA
retrieved
27 February 2018
stated in
Differentiation of human monocytes in vitro with granulocyte-macrophage colony-stimulating factor and macrophage colony-stimulating factor produces distinct changes in cGMP phosphodiesterase expression
GOA
curator
UniProt
UniProt protein ID
O00408
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00408&geneProductId=UniProtKB:O00408
determination method or standard
IDA

Identifiers

Ensembl protein ID
 
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