Differential activities of murine single minded 1 (SIM1) and SIM2 on a hypoxic response element. Cross-talk between basic helix-loop-helix/per-Arnt-Sim homology transcription factors (Q24292132)

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Language	Label	Description	Also known as
English	Differential activities of murine single minded 1 (SIM1) and SIM2 on a hypoxic response element. Cross-talk between basic helix-loop-helix/per-Arnt-Sim homology transcription factors	scientific article

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scholarly article

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Differential activities of murine single minded 1 (SIM1) and SIM2 on a hypoxic response element. Cross-talk between basic helix-loop-helix/per-Arnt-Sim homology transcription factors (English)

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Endothelial PAS domain protein 1

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GOA release 2020-03-11

aryl hydrocarbon receptor

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GOA release 2020-03-11

Hypoxia inducible factor 1 subunit alpha

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GOA release 2020-03-11

Aryl hydrocarbon receptor nuclear translocator 2

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GOA release 2020-03-11

regulation of transcription, DNA-templated

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GOA release 2020-03-11

Single-minded family bHLH transcription factor 2

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GOA release 2020-03-11

Aryl hydrocarbon receptor nuclear translocator 2

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GOA release 2020-03-11

Single-minded family bHLH transcription factor 1

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GOA release 2020-03-11

Endothelial PAS domain protein 1

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GOA release 2020-03-11

Aryl-hydrocarbon receptor

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GOA release 2020-03-11

Aryl hydrocarbon receptor nuclear translocator

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GOA release 2020-03-11

Hypoxia inducible factor 1, alpha subunit

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GOA release 2020-03-11

author name string

Susan L Woods

1

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Murray L Whitelaw

2

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language of work or name

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publication date

22 March 2002

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Journal of Biological Chemistry

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277

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12

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10236-43

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The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development

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The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling

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HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

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Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

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Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice

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The PAS superfamily: sensors of environmental and developmental signals

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Molecular bases for circadian clocks

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Mop3 is an essential component of the master circadian pacemaker in mammals

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21 January 2018

The Drosophila single-minded gene encodes a helix-loop-helix protein that acts as a master regulator of CNS midline development

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Tubulogenesis in Drosophila: a requirement for the trachealess gene product

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trachealess encodes a bHLH-PAS protein that is an inducer of tracheal cell fates in Drosophila

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Remembrance of things PAS: regulation of development by bHLH-PAS proteins

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Two new members of the murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesis

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21 January 2018

Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome

1 reference

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21 January 2018

Two murine homologs of the Drosophila single-minded protein that interact with the mouse aryl hydrocarbon receptor nuclear translocator protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110752200

21 January 2018

cDNA cloning of a murine homologue of Drosophila single-minded, its mRNA expression in mouse development, and chromosome localization.

1 reference

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21 January 2018

Characterization of msim, a murine homologue of the Drosophila sim transcription factor.

1 reference

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21 January 2018

The mammalian single-minded (SIM) gene: mouse cDNA structure and diencephalic expression indicate a candidate gene for Down syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110752200

21 January 2018

Molecular mechanisms of human single-minded 2 (SIM2) gene expression: identification of a promoter site in the SIM2 genomic sequence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110752200

21 January 2018

Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110752200

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Profound obesity associated with a balanced translocation that disrupts the SIM1 gene

1 reference

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Sim1 haploinsufficiency causes hyperphagia, obesity and reduction of the paraventricular nucleus of the hypothalamus

1 reference

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21 January 2018

CNS midline enhancers of the Drosophila slit and Toll genes

1 reference

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A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110752200

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Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110752200

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Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110752200

21 January 2018

cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS factor (Arnt2) with close sequence similarity to the aryl hydrocarbon receptor nuclear translocator (Arnt)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110752200

21 January 2018

The murine Sim-2 gene product inhibits transcription by active repression and functional interference

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110752200

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DNA Binding Specificities and Pairing Rules of the Ah Receptor, ARNT, and SIM Proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110752200

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The PAS domain confers target gene specificity of Drosophila bHLH/PAS proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110752200

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Interaction between the bHLH-PAS protein Trachealess and the POU-domain protein Drifter, specifies tracheal cell fates.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110752200

21 January 2018

Different transcriptional properties of mSim-1 and mSim-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110752200

21 January 2018

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

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Development of a bicistronic vector driven by the human polypeptide chain elongation factor 1alpha promoter for creation of stable mammalian cell lines that express very high levels of recombinant proteins

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Multiple roles of ligand in transforming the dioxin receptor to an active basic helix-loop-helix/PAS transcription factor complex with the nuclear protein Arnt

1 reference

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Definition of a dioxin receptor mutant that is a constitutive activator of transcription: delineation of overlapping repression and ligand binding functions within the PAS domain

1 reference

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Identification of transactivation and repression functions of the dioxin receptor and its basic helix-loop-helix/PAS partner factor Arnt: inducible versus constitutive modes of regulation

1 reference

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A common multiple cloning site in a set of vectors for expression of eukaryotic genes in mammalian, insect and bacterial cells

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The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase

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Cross-coupling of signal transduction pathways: the dioxin receptor mediates induction of cytochrome P-450IA1 expression via a protein kinase C-dependent mechanism

1 reference

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Ligand-dependent recruitment of the Arnt coregulator determines DNA recognition by the dioxin receptor

1 reference

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Possible function of Ah receptor nuclear translocator (Arnt) homodimer in transcriptional regulation

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Analysis of chromatin structure by in vivo formaldehyde cross-linking.

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Cloning and expression analysis of a novel mouse gene with sequence similarity to the Drosophila fat facets gene

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Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha

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Purification and characterization of hypoxia-inducible factor 1

1 reference

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Expression of ARNT, ARNT2, HIF1 alpha, HIF2 alpha and Ah receptor mRNAs in the developing mouse.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110752200

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Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

1 reference

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Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

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Hypoxia increases the association of 4E-binding protein 1 with the initiation factor 4E in isolated rat hepatocytes

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Mild impairment of learning and memory in mice overexpressing the mSim2 gene located on chromosome 16: an animal model of Down's syndrome

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Identification of a novel mechanism of regulation of Ah (dioxin) receptor function

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Allosteric effects of DNA on transcriptional regulators

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Allosteric effects of Pit-1 DNA sites on long-term repression in cell type specification

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Unifying theory of hypoxia tolerance: molecular/metabolic defense and rescue mechanisms for surviving oxygen lack.

1 reference

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Translation of vascular endothelial growth factor mRNA by internal ribosome entry: implications for translation under hypoxia

1 reference

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Mice trisomic for a bacterial artificial chromosome with the single-minded 2 gene (Sim2) show phenotypes similar to some of those present in the partial trisomy 16 mouse models of Down syndrome

1 reference

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ARNT2 acts as the dimerization partner of SIM1 for the development of the hypothalamus

1 reference

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21 January 2018

Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway

1 reference

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21 January 2018

Efficient translation of mouse hypoxia-inducible factor-1alpha under normoxic and hypoxic conditions

1 reference

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Functional interactions between Drosophila bHLH/PAS, Sox, and POU transcription factors regulate CNS midline expression of the slit gene.

1 reference

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based on heuristic

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Modifications of vectors pEF-BOS, pcDNA1 and pcDNA3 result in improved convenience and expression

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10.1074/JBC.M110752200

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Consolidated OpenCitations Corpus – April 2017

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OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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