ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis (Q24316186)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1903064

regulation of reverse cholesterol transport

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1903062

negative regulation of reverse cholesterol transport

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1903063

Nuclear receptor subfamily 1 group H member 2

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ATP binding cassette subfamily A member 1

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ATP binding cassette subfamily A member 12

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protein localization to plasma membrane

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Nuclear receptor subfamily 1, group H, member 2

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ATP-binding cassette, sub-family A (ABC1), member 1

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ATP-binding cassette, sub-family A (ABC1), member 12

1 reference

1 reference

Benjamin T Kile

13

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Garry L. Jennings

object named as

Garry Jennings

11

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author name string

Ying Fu

1

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Nigora Mukhamedova

2

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Sally Ip

3

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Wilissa D'Souza

4

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Katya J Henley

5

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Tia DiTommaso

6

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Rajitha Kesani

7

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Michael Ditiatkovski

8

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Lynelle Jones

9

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Rachael M Lane

10

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Ian M Smyth

12

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Dmitri Sviridov

On the mechanism for PPAR agonists to enhance ABCA1 gene expression

14

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language of work or name

English

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publication date

6 August 2013

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published in

Cell Metabolism

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volume

18

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issue

2

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page(s)

225-38

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cites work

1 reference

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7 January 2021

ABC transporters, atherosclerosis and inflammation

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The role of different regions of ATP-binding cassette transporter A1 in cholesterol efflux

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Role of cholesterol and lipid organization in disease

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In vitro cultivation and differentiation of fetal liver stem cells from mice

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Flow-cytometric separation and enrichment of hepatic progenitor cells in the developing mouse liver

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Synthetic LXR ligand inhibits the development of atherosclerosis in mice

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Cellular localization and trafficking of the human ABCA1 transporter

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Novel insights into the cellular mechanisms of the anti-inflammatory effects of NF-kappaB essential modulator binding domain peptides

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Liver X receptor beta (LXRbeta) interacts directly with ATP-binding cassette A1 (ABCA1) to promote high density lipoprotein formation during acute cholesterol accumulation

1 reference

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7 January 2021

ABCA12 maintains the epidermal lipid permeability barrier by facilitating formation of ceramide linoleic esters

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Mutations in ABCA12 underlie the severe congenital skin disease harlequin ichthyosis.

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Harlequin ichthyosis model mouse reveals alveolar collapse and severe fetal skin barrier defects

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LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor

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Identification of the cAMP-responsive enhancer of the murine ABCA1 gene: requirement for CREB1 and STAT3/4 elements

1 reference

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7 January 2021

Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses

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Liver x receptor signaling pathways and atherosclerosis

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Liver X receptors as integrators of metabolic and inflammatory signaling

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Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo

1 reference

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A gel-based method for purification of apolipoprotein A-I from small volumes of plasma.

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Demethylation using the epigenetic modifier, 5-azacytidine, increases the efficiency of transient transfection of macrophages

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HIV-1 Nef mobilizes lipid rafts in macrophages through a pathway that competes with ABCA1-dependent cholesterol efflux

1 reference

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cAMP induces ABCA1 phosphorylation activity and promotes cholesterol efflux from fibroblasts

1 reference

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7 January 2021

Enhancing apolipoprotein A-I-dependent cholesterol efflux elevates cholesterol export from macrophages in vivo

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Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL

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Quantitative colocalization analysis of multicolor confocal immunofluorescence microscopy images: pushing pixels to explore biological phenomena

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Human immunodeficiency virus impairs reverse cholesterol transport from macrophages

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A mouse model of harlequin ichthyosis delineates a key role for Abca12 in lipid homeostasis

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Self-improvement of keratinocyte differentiation defects during skin maturation in ABCA12-deficient harlequin ichthyosis model mice.

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7 January 2021