The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities. (Q27934866)

PubMed

1 December 2016

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19060898%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19060898%20AND%20SRC:MED&resulttype=core&format=json

Exosome non-catalytic core subunit CSL4 YNL232W

18 January 2020

main subject

1 reference

Exosome catalytic subunit DIS3 YOL021C

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Ana Barbas

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19060898%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Filipa Pereira Reis

4

1 reference

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18 January 2020

Cecília Maria Arraiano

7

1 reference

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18 January 2020

author name string

Daneen Schaeffer

1

1 reference

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18 January 2020

Maya Sanchez-Rotunno

6

1 reference

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18 January 2020

Borislava Tsanova

2

1 reference

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18 January 2020

Eeshita Ghosh Dastidar

5

1 reference

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18 January 2020

Ambro van Hoof

8

1 reference

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18 January 2020

language of work or name

English

0 references

publication date

7 December 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19060898%20AND%20SRC:MED&resulttype=core&format=json

Nature Structural & Molecular Biology

18 January 2020

published in

2 references

PubMed

1 December 2016

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19060898%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

16

1 reference

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18 January 2020

issue

1

1 reference

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18 January 2020

page(s)

56-62

1 reference

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SMG6 promotes endonucleolytic cleavage of nonsense mRNA in human cells

18 January 2020

cites work

1 reference

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Crystal structure of PAE0151 from Pyrobaculum aerophilum, a PIN-domain (VapC) protein from a toxin-antitoxin operon

20 March 2017

1 reference

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Structure of the active subunit of the yeast exosome core, Rrp44: diverse modes of substrate recruitment in the RNase II nuclease family

20 March 2017

1 reference

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Insights into the mechanism of progressive RNA degradation by the archaeal exosome

20 March 2017

1 reference

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Architecture of the yeast Rrp44 exosome complex suggests routes of RNA recruitment for 3' end processing

20 March 2017

1 reference

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A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism

20 March 2017

1 reference

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The exosome subunit Rrp44 plays a direct role in RNA substrate recognition

20 March 2017

1 reference

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Reconstitution, activities, and structure of the eukaryotic RNA exosome

20 March 2017

1 reference

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A single subunit, Dis3, is essentially responsible for yeast exosome core activity

20 March 2017

1 reference

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Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex

20 March 2017

1 reference

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The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation

20 March 2017

1 reference

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Yeast transcripts cleaved by an internal ribozyme provide new insight into the role of the cap and poly(A) tail in translation and mRNA decay

20 March 2017

1 reference

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MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies

20 March 2017

1 reference

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A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies

20 March 2017

1 reference

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PIN domain of Nob1p is required for D-site cleavage in 20S pre-rRNA

20 March 2017

1 reference

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Cytoplasmic foci are sites of mRNA decay in human cells

20 March 2017

1 reference

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Distant structural homology leads to the functional characterization of an archaeal PIN domain as an exonuclease

20 March 2017

1 reference

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The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic foci

20 March 2017

1 reference

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Functional profiling of the Saccharomyces cerevisiae genome

20 March 2017

1 reference

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Exosome-mediated recognition and degradation of mRNAs lacking a termination codon

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615074

Arabidopsis thaliana exosome subunit AtRrp4p is a hydrolytic 3'-->5' exonuclease containing S1 and KH RNA-binding domains

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615074

Exoribonuclease superfamilies: structural analysis and phylogenetic distribution

20 March 2017

1 reference

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Prediction of the archaeal exosome and its connections with the proteasome and the translation and transcription machineries by a comparative-genomic approach

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615074

A duplicated fold is the structural basis for polynucleotide phosphorylase catalytic activity, processivity, and regulation

20 March 2017

1 reference

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Function of the ski4p (Csl4p) and Ski7p proteins in 3'-to-5' degradation of mRNA

20 March 2017

1 reference

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Three conserved members of the RNase D family have unique and overlapping functions in the processing of 5S, 5.8S, U4, U5, RNase MRP and RNase P RNAs in yeast

20 March 2017

1 reference

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Yeast exosome mutants accumulate 3'-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAs

20 March 2017

1 reference

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Large-scale analysis of the yeast genome by transposon tagging and gene disruption

20 March 2017

1 reference

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Functions of the exosome in rRNA, snoRNA and snRNA synthesis

20 March 2017

1 reference

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The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

20 March 2017

1 reference

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The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex

20 March 2017

1 reference

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Dob1p (Mtr4p) is a putative ATP-dependent RNA helicase required for the 3' end formation of 5.8S rRNA in Saccharomyces cerevisiae

20 March 2017

1 reference

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The proofreading domain of Escherichia coli DNA polymerase I and other DNA and/or RNA exonuclease domains

20 March 2017

1 reference

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The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases

20 March 2017

1 reference

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Comparative sequence analysis of ribonucleases HII, III, II PH and D

20 March 2017

1 reference

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A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

20 March 2017

1 reference

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Structural basis of 3' end RNA recognition and exoribonucleolytic cleavage by an exosome RNase PH core

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615074

The archaeal exosome core is a hexameric ring structure with three catalytic subunits

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615074

A mouse cytoplasmic exoribonuclease (mXRN1p) with preference for G4 tetraplex substrates

20 March 2017

1 reference

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Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells

20 March 2017

1 reference

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Turnover mechanisms of the stable yeast PGK1 mRNA

20 March 2017

1 reference

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An equivalent metal ion in one- and two-metal-ion catalysis

7 April 2017

1 reference

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Exoribonucleases and their multiple roles in RNA metabolism

29 September 2017

1 reference

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Ribonuclease E is a 5'-end-dependent endonuclease

29 September 2017

1 reference

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Synthetic lethality of sep1 (xrn1) ski2 and sep1 (xrn1) ski3 mutants of Saccharomyces cerevisiae is independent of killer virus and suggests a general role for these genes in translation control

29 September 2017

1 reference

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VapC-1 of nontypeable Haemophilus influenzae is a ribonuclease

29 September 2017

1 reference

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A protein complex mediating mRNA degradation in Escherichia coli.

2 June 2018

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2 June 2018

1 reference

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Genome-wide high-resolution mapping of exosome substrates reveals hidden features in the Arabidopsis transcriptome

2 June 2018

1 reference

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Unravelling the dynamics of RNA degradation by ribonuclease II and its RNA-bound complex.

27 November 2018

1 reference

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Crystal structure of a PIN (PilT N-terminus) domain (AF0591) from Archaeoglobus fulgidus at 1.90 A resolution

27 November 2018

1 reference

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Copurification of E. coli RNAase E and PNPase: evidence for a specific association between two enzymes important in RNA processing and degradation.

27 November 2018

1 reference

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Structural framework for the mechanism of archaeal exosomes in RNA processing

27 November 2018

1 reference

New Insights into the Mechanism of RNA Degradation by Ribonuclease II

31 March 2020

1 reference

A single mutation in Escherichia coli ribonuclease II inactivates the enzyme without affecting RNA binding

31 March 2020

1 reference

Characterization of the functional domains of Escherichia coli RNase II.

31 March 2020

1 reference

Drosophila gene tazman, an orthologue of the yeast exosome component Rrp44p/Dis3, is differentially expressed during development.

31 March 2020

1 reference

Endonucleolytic RNA cleavage by a eukaryotic exosome

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB.1528

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19060898%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

18 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19060898%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

2 references

PubMed

1 December 2016