The S. cerevisiae SAGA complex functions in vivo as a coactivator for transcriptional activation by Gal4. (Q27940298)

1 December 2016

title

The S. cerevisiae SAGA complex functions in vivo as a coactivator for transcriptional activation by Gal4. (English)

1 reference

Transcriptional regulator SPT3 YDR392W

1 December 2016

main subject

1 reference

GOA release 2020-03-11

author name string

E Larschan

series ordinal

1

0 references

F Winston

series ordinal

2

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language of work or name

English

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publication date

1 August 2001

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1 reference

Recruitment of HAT complexes by direct activator interactions with the ATM-related Tra1 subunit

1 December 2016

volume

15

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issue

15

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page(s)

1946-56

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cites work

1 reference

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20 March 2017

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Evidence for Gal3p's cytoplasmic location and Gal80p's dual cytoplasmic-nuclear location implicates new mechanisms for controlling Gal4p activity in Saccharomyces cerevisiae

20 March 2017

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Distinct classes of yeast promoters revealed by differential TAF recruitment

20 March 2017

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Inhibition of TATA-binding protein function by SAGA subunits Spt3 and Spt8 at Gcn4-activated promoters

20 March 2017

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Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle- and developmentally regulated promoter.

20 March 2017

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Functional organization of the yeast SAGA complex: distinct components involved in structural integrity, nucleosome acetylation, and TATA-binding protein interaction.

20 March 2017

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A transcriptional activating region with two contrasting modes of protein interaction

20 March 2017

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Characterization of a human homologue of the Saccharomyces cerevisiae transcription factor spt3 (SUPT3H)

20 March 2017

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Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family

20 March 2017

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A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation

20 March 2017

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An activator target in the RNA polymerase II holoenzyme

20 March 2017

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Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex

20 March 2017

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ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3.

20 March 2017

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SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast

20 March 2017

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Human TAF(II28) promotes transcriptional stimulation by activation function 2 of the retinoid X receptors

20 March 2017

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ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription

20 March 2017

1 reference

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Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription.

20 March 2017

1 reference

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Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID

20 March 2017

1 reference

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Specific DNA binding of GAL4, a positive regulatory protein of yeast

20 March 2017

1 reference

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SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae, encodes an acidic nuclear protein with a carboxy-terminal repeat

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Evidence that SNF2/SWI2 and SNF5 activate transcription in yeast by altering chromatin structure

20 March 2017

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Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications

20 March 2017

1 reference

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Multifunctional yeast high-copy-number shuttle vectors

20 March 2017

1 reference

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Construction of a set of convenient Saccharomyces cerevisiae strains that are isogenic to S288C

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

SAGA is an essential in vivo target of the yeast acidic activator Gal4p

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of Jun

20 March 2017

1 reference

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Regulation of gene expression by TBP-associated proteins

20 March 2017

1 reference

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Histone acetyltransferases

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Binding of TBP to promoters in vivo is stimulated by activators and requires Pol II holoenzyme

7 April 2017

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Transcriptional activators direct histone acetyltransferase complexes to nucleosomes

7 April 2017

1 reference

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Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains

7 April 2017

1 reference

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Redundant roles for the TFIID and SAGA complexes in global transcription

7 April 2017

1 reference

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Distribution of acetylated histones resulting from Gal4-VP16 recruitment of SAGA and NuA4 complexes

29 September 2017

1 reference

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Multiple signals regulate GAL transcription in yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

The Spt components of SAGA facilitate TBP binding to a promoter at a post-activator-binding step in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

The Gal3p-Gal80p-Gal4p transcription switch of yeast: Gal3p destabilizes the Gal80p-Gal4p complex in response to galactose and ATP.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Histone acetyltransferase complexes can mediate transcriptional activation by the major glucocorticoid receptor activation domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

The SAGA of Spt proteins and transcriptional analysis in yeast: past, present, and future

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Synergistic transcriptional activation by TATA-binding protein and hTAFII28 requires specific amino acids of the hTAFII28 histone fold

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Cell cycle-regulated histone acetylation required for expression of the yeast HO gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

The Gcn4p activation domain interacts specifically in vitro with RNA polymerase II holoenzyme, TFIID, and the Adap-Gcn5p coactivator complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Essential functional interactions of SAGA, a Saccharomyces cerevisiae complex of Spt, Ada, and Gcn5 proteins, with the Snf/Swi and Srb/mediator complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function in vivo.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Quantitation of putative activator-target affinities predicts transcriptional activating potentials

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Characterization of NGG1, a novel yeast gene required for glucose repression of GAL4p-regulated transcription.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Mapping Polycomb-repressed domains in the bithorax complex using in vivo formaldehyde cross-linked chromatin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

GAL4 interacts with TATA-binding protein and coactivators

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Transcriptional regulation in the yeast GAL gene family: a complex genetic network

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

In vivo DNA-binding properties of a yeast transcription activator protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Yeast regulatory gene GAL3: carbon regulation; UASGal elements in common with GAL1, GAL2, GAL7, GAL10, GAL80, and MEL1; encoded protein strikingly similar to yeast and Escherichia coli galactokinases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

GAL4 protein: purification, association with GAL80 protein, and conserved domain structure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Eukaryotic coactivators associated with the TATA box binding protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

A conserved motif present in a class of helix-loop-helix proteins activates transcription by direct recruitment of the SAGA complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

The SAGA unfolds: convergence of transcription regulators in chromatin-modifying complexes.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

The yeast galactose genetic switch is mediated by the formation of a Gal4p-Gal80p-Gal3p complex

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Essential and redundant functions of histone acetylation revealed by mutation of target lysines and loss of the Gcn5p acetyltransferase

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

pMPY-ZAP: a reusable polymerase chain reaction-directed gene disruption cassette for Saccharomyces cerevisiae.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

The organization and transcription of the galactose gene cluster of Saccharomyces

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Nondissociation of GAL4 and GAL80 in vivo after galactose induction

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

A transcriptionally active form of GAL4 is phosphorylated and associated with GAL80

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Identification and analysis of homologues of Saccharomyces cerevisiae Spt3 suggest conserved functional domains

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Structure/functional properties of the yeast dual regulator protein NGG1 that are required for glucose repression.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

The acidic transcriptional activation domains of herpes virus VP16 and yeast HAP4 have different co-factor requirements.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312753

Gcn4 activator targets Gcn5 histone acetyltransferase to specific promoters independently of transcription

27 November 2018

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12 December 2020

Critical structural elements of the VP16 transcriptional activation domain

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12 December 2020

A simplified formaldehyde fixation and immunoprecipitation technique for studying protein-DNA interactions

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12 December 2020

SPT3 interacts with TFIID to allow normal transcription in Saccharomyces cerevisiae

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12 December 2020

Characterization of Physical Interactions of the Putative Transcriptional Adaptor, ADA2, with Acidic Activation Domains and TATA-binding Protein

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12 December 2020

yTAFII61 has a general role in RNA polymerase II transcription and is required by Gcn4p to recruit the SAGA coactivator complex

1 reference

12 December 2020

Identifiers

DOI

10.1101/GAD.911501

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