CD14 cooperates with complement receptor 3 to mediate MyD88-independent phagocytosis of Borrelia burgdorferi (Q28257106)

12

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author name string

Kelly L Hawley

1

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Chris M Olson

2

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Juan M Iglesias-Pedraz

3

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Nicolás Navasa

4

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Jorge L Cervantes

5

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Melissa J Caimano

6

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Hooman Izadi

7

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Utpal Pal

9

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Juan C Salazar

10

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Justin D Radolf

Proceedings of the National Academy of Sciences of the United States of America

11

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language of work or name

English

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publication date

24 January 2012

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published in

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volume

109

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issue

4

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page(s)

1228-32

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cites work

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Live imaging reveals a biphasic mode of dissemination of Borrelia burgdorferi within ticks

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Downstream signals for MyD88-mediated phagocytosis of Borrelia burgdorferi can be initiated by TRIF and are dependent on PI3K.

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Activation of human monocytes by live Borrelia burgdorferi generates TLR2-dependent and -independent responses which include induction of IFN-beta

29 September 2017

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Local production of IFN-gamma by invariant NKT cells modulates acute Lyme carditis

29 September 2017

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Distinct roles for MyD88 and Toll-like receptors 2, 5, and 9 in phagocytosis of Borrelia burgdorferi and cytokine induction

29 September 2017

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CD44-mediated phagocytosis induces inside-out activation of complement receptor-3 in murine macrophages

29 September 2017

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Borrelia burgdorferi BBB07 interaction with integrin alpha3beta1 stimulates production of pro-inflammatory mediators in primary human chondrocytes

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Phagocytosis of Borrelia burgdorferi and Treponema pallidum potentiates innate immune activation and induces gamma interferon production

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Cross-talk between CD14 and complement receptor 3 promotes phagocytosis of mycobacteria: regulation by phosphatidylinositol 3-kinase and cytohesin-1.

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Integrin activation takes shape

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29 September 2017

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Integrin CR3 mediates the binding of nonspecifically opsonized Borrelia burgdorferi to human phagocytes and mammalian cells

29 September 2017

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29 September 2017

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Recruitment of macrophages and polymorphonuclear leukocytes in Lyme carditis

2 June 2018

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Complement receptor 3 binds the Borrelia burgdorferi outer surface proteins OspA and OspB in an iC3b-independent manner

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Integrin activation by bacterial fimbriae through a pathway involving CD14, Toll-like receptor 2, and phosphatidylinositol-3-kinase

27 November 2018

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Cutting edge: cells that carry A null allele for toll-like receptor 2 are capable of responding to endotoxin.

27 November 2018

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Surface receptors of neutrophils towards B. burgdorferi

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12 December 2020

Activation of human monocytic cells by Borrelia burgdorferi and Treponema pallidum is facilitated by CD14 and correlates with surface exposure of spirochetal lipoproteins

1 reference

12 December 2020

Signaling through CD14 attenuates the inflammatory response to Borrelia burgdorferi, the agent of Lyme disease

1 reference

12 December 2020

Peptide-mediated interference of TIR domain dimerization in MyD88 inhibits interleukin-1-dependent activation of NF-{kappa}B

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12 December 2020

Critical role for serum opsonins and complement receptors CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in phagocytosis of Francisella tularensis by human dendritic cells (DC): uptake of Francisella leads to activation of immature DC and intracellular survi

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12 December 2020

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12 December 2020

Integrin regulation of leukocyte inflammatory functions. CD11b/CD18 enhancement of the tumor necrosis factor-alpha responses of monocytes

1 reference

12 December 2020

Involvement of CD14 and complement receptors CR3 and CR4 in nuclear factor-kappaB activation and TNF production induced by lipopolysaccharide and group B streptococcal cell walls

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12 December 2020