Molecular determinants of metabotropic glutamate receptor signaling. (Q32140641)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11239574%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

review article

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title

Molecular determinants of metabotropic glutamate receptor signaling (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11239574%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

author name string

A De Blasi

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11239574%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

J Pin

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11239574%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

publication date

1 March 2001

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Trends in Pharmacological Sciences

5 November 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11239574%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

volume

22

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5 November 2019

issue

3

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5 November 2019

page(s)

114-120

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The metabotropic glutamate receptor (mGluR1 alpha) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction.

5 November 2019

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The non-competitive antagonists 2-methyl-6-(phenylethynyl)pyridine and 7-hydroxyiminocyclopropan[b]chromen-1a-carboxylic acid ethyl ester interact with overlapping binding pockets in the transmembrane region of group I metabotropic glutamate recepto

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How receptors talk to trimeric G proteins

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Domains involved in the specificity of G protein activation in phospholipase C-coupled metabotropic glutamate receptors.

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The second intracellular loop of metabotropic glutamate receptor 1 cooperates with the other intracellular domains to control coupling to G-proteins.

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Role of the second and third intracellular loops of metabotropic glutamate receptors in mediating dual signal transduction activation

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Amino acids in the second and third intracellular loops of the parathyroid Ca2+-sensing receptor mediate efficient coupling to phospholipase C.

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Metabotropic glutamate receptor 5 is a disulfide-linked dimer

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7 January 2021

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7 January 2021

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Protein kinase C and A3 adenosine receptor activation inhibit presynaptic metabotropic glutamate receptor (mGluR) function and uncouple mGluRs from GTP-binding proteins.

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Phorbol ester and forskolin suppress the presynaptic inhibitory action of group-II metabotropic glutamate receptor at rat hippocampal mossy fibre synapse

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Activation of PKC disrupts presynaptic inhibition by group II and group III metabotropic glutamate receptors and uncouples the receptor from GTP-binding proteins

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RGS4 and GAIP are GTPase-activating proteins for Gq alpha and block activation of phospholipase C beta by gamma-thio-GTP-Gq alpha

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7 January 2021

RGS4 inhibits signaling by group I metabotropic glutamate receptors.

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Expression of RGS2 alters the coupling of metabotropic glutamate receptor 1a to M-type K+ and N-type Ca2+ channels

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7 January 2021

10.1016/S0165-6147(00)01635-7

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5 November 2019

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24 November 2022

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