Dysregulation of Met receptor tyrosine kinase activity in invasive tumors (Q34584046)

3 August 2017

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title

Dysregulation of Met receptor tyrosine kinase activity in invasive tumors (English)

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3 August 2017

author name string

Alla Danilkovitch-Miagkova

series ordinal

1

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3 August 2017

Berton Zbar

series ordinal

2

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3 August 2017

language of work or name

English

0 references

publication date

1 April 2002

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Journal of Clinical Investigation

3 August 2017

published in

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3 August 2017

volume

109

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3 August 2017

issue

7

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3 August 2017

page(s)

863-867

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The cadherin-catenin adhesion system in signaling and cancer

3 August 2017

cites work

1 reference

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Invasive growth: from development to metastasis

7 July 2018

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Oncogenic mutants of RON and MET receptor tyrosine kinases cause activation of the beta-catenin pathway

7 July 2018

1 reference

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Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice

7 July 2018

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Structural basis of oncogenic activation caused by point mutations in the kinase domain of the MET proto-oncogene: modeling studies

7 July 2018

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A novel germ line juxtamembrane Met mutation in human gastric cancer

7 July 2018

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Cross-talk between the proto-oncogenes Met and Ron

7 July 2018

1 reference

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Enhanced transformation by a plasma membrane-associated met oncoprotein: activation of a phosphoinositide 3'-kinase-dependent autocrine loop involving hyaluronic acid and CD44.

7 July 2018

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Cross-talk between epidermal growth factor receptor and c-Met signal pathways in transformed cells

7 July 2018

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Novel mutation in the ATP-binding site of the MET oncogene tyrosine kinase in a HPRCC family

7 July 2018

1 reference

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Cross-talk between CD44 and c-Met in B cells

7 July 2018

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Novel mutations of the MET proto-oncogene in papillary renal carcinomas.

7 July 2018

1 reference

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Uncoupling signal transducers from oncogenic MET mutants abrogates cell transformation and inhibits invasive growth

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150937

Activating mutations for the met tyrosine kinase receptor in human cancer

7 July 2018

1 reference

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Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas

7 July 2018

1 reference

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Transgenic expression in the liver of truncated Met blocks apoptosis and permits immortalization of hepatocytes

7 July 2018

1 reference

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Cellular adherence elicits ligand-independent activation of the Met cell-surface receptor

7 July 2018

1 reference

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Transgenic expression of tpr-met oncogene leads to development of mammary hyperplasia and tumors

7 July 2018

1 reference

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Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase

7 July 2018

1 reference

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Structural and functional domains critical for constitutive activation of the HGF-receptor (Met).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150937

Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150937

Defective posttranslational processing activates the tyrosine kinase encoded by the MET proto-oncogene (hepatocyte growth factor receptor).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150937

Evidence for non-covalent clusters of the c-met proto-oncogene product

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150937

Tumorigenesis mediated by MET mutant M1268T is inhibited by dominant-negative Src.

7 July 2018

1 reference

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Overexpression of the hepatocyte growth factor (HGF) receptor (Met) and presence of a truncated and activated intracellular HGF receptor fragment in locally aggressive/malignant human musculoskeletal tumors.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150937

Different point mutations in the met oncogene elicit distinct biological properties.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150937

Signaling requirements for oncogenic forms of the Met tyrosine kinase receptor.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150937

Molecular cloning of a new transforming gene from a chemically transformed human cell line.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150937

Constitutive activation of c-Met in liver metastatic B16 melanoma cells depends on both substrate adhesion and cell density and is regulated by a cytosolic tyrosine phosphatase activity

27 October 2018

1 reference

12 December 2020

Somatic mutations of the MET oncogene are selected during metastatic spread of human HNSC carcinomas

1 reference

12 December 2020

Somatic mutations in the kinase domain of the Met/hepatocyte growth factor receptor gene in childhood hepatocellular carcinomas

1 reference

12 December 2020

Heparan Sulfate-modified CD44 Promotes Hepatocyte Growth Factor/Scatter Factor-induced Signal Transduction through the Receptor Tyrosine Kinase c-Met

1 reference

12 December 2020

Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression

1 reference

12 December 2020

The Met/HGF receptor is over-expressed in human osteosarcomas and is activated by either a paracrine or an autocrine circuit

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI0215418

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3 August 2017

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3 August 2017

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