A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I. (Q34827947)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12511593%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

title

A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I (English)

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16 December 2019

4

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16 December 2019

David L. Silver

6

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16 December 2019

author name string

Nan Wang

1

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16 December 2019

Wengen Chen

2

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16 December 2019

Birgit Agerholm-Larsen

5

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16 December 2019

Alan R Tall

7

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16 December 2019

Patrick Linsel-Nitschke

3

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16 December 2019

language of work or name

English

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publication date

1 January 2003

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Journal of Clinical Investigation

16 December 2019

published in

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16 December 2019

volume

111

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16 December 2019

issue

1

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16 December 2019

page(s)

99-107

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ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages. Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity

16 December 2019

cites work

1 reference

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Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I

8 July 2018

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Synthetic LXR ligand inhibits the development of atherosclerosis in mice

8 July 2018

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Helical apolipoproteins stabilize ATP-binding cassette transporter A1 by protecting it from thiol protease-mediated degradation

8 July 2018

1 reference

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Pivotal role of ABCA1 in reverse cholesterol transport influencing HDL levels and susceptibility to atherosclerosis

8 July 2018

1 reference

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Monocyte/macrophage expression of ABCA1 has minimal contribution to plasma HDL levels

8 July 2018

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Preferential ATP-binding cassette transporter A1-mediated cholesterol efflux from late endosomes/lysosomes

8 July 2018

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The structure of calpain.

8 July 2018

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ATP-binding cassette transporter A1 (ABCA1) functions as a cholesterol efflux regulatory protein

8 July 2018

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Apolipoprotein specificity for lipid efflux by the human ABCAI transporter

8 July 2018

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Role of LXRs in control of lipogenesis

8 July 2018

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Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

8 July 2018

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Tangier disease as a test of the reverse cholesterol transport hypothesis

8 July 2018

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8 July 2018

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Concentrations of electrophoretic and size subclasses of apolipoprotein A-I-containing particles in human peripheral lymph

8 July 2018

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ABCA1 is the cAMP-inducible apolipoprotein receptor that mediates cholesterol secretion from macrophages

8 July 2018

1 reference

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Specific binding of ApoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1.

8 July 2018

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Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor

8 July 2018

1 reference

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Calpain inhibitors as therapeutic agents in nerve and muscle degeneration

8 July 2018

1 reference

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Free cholesterol loading of macrophages induces apoptosis involving the fas pathway.

8 July 2018

1 reference

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The PEST domain of IkappaBalpha is necessary and sufficient for in vitro degradation by mu-calpain

8 July 2018

1 reference

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Stimulation of fecal steroid excretion after infusion of recombinant proapolipoprotein A-I. Potential reverse cholesterol transport in humans

8 July 2018

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Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

8 July 2018

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Molecular cloning of the human ATP-binding cassette transporter 1 (hABC1): evidence for sterol-dependent regulation in macrophages.

8 July 2018

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A large PEST-like sequence directs the ubiquitination, endocytosis, and vacuolar degradation of the yeast a-factor receptor

8 July 2018

1 reference

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PEST sequences and regulation by proteolysis

8 July 2018

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Human apolipoprotein A-I gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse

8 July 2018

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Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice

8 July 2018

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The cholesteryl ester cycle in macrophage foam cells. Continual hydrolysis and re-esterification of cytoplasmic cholesteryl esters.

8 July 2018

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The effects of subfractions of high density lipoprotein on cholesterol efflux from cultured fibroblasts. Regulation of low density lipoprotein receptor activity

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Protein serine/threonine phosphatase inhibitors suppress phenobarbital-induced Cyp2b10 gene transcription in mouse primary hepatocytes

26 October 2018

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Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers

26 October 2018

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12 December 2020

Engulfment of apoptotic cells involves the redistribution of membrane phosphatidylserine on phagocyte and prey

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12 December 2020

Method-dependent changes in "HDL-cholesterol" with recombinant apolipoprotein A-I(Milano) infusion in healthy volunteers

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12 December 2020

Hydrolysis and excretion of cytoplasmic cholesteryl esters by macrophages: stimulation by high density lipoprotein and other agents

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12 December 2020

Coronary heart disease prevalence and other clinical features in familial high-density lipoprotein deficiency (Tangier disease)

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12 December 2020

The amino-terminal hydrophobic region of the small subunit of calcium-activated neutral protease (CANP) is essential for its activation by phosphatidylinositol

1 reference

12 December 2020

Synthesis of a new cell penetrating calpain inhibitor (calpeptin)

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI200316808

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12511593%20AND%20SRC:MED&resulttype=core&format=json

release_qnhpoug23bhatig4rnv6d5mxfe

16 December 2019

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/qnhpoug23bhatig4rnv6d5mxfe

24 November 2022

mapped directly with Wikidata item

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16 December 2019

PubMed publication ID

12511593

1 reference