MECHANISMS OF RESISTANCE TO ANTICANCER AGENTS. (Q35443005)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14153765%20AND%20SRC:MED&resulttype=core&format=json

29 November 2019

review article

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title

MECHANISMS OF RESISTANCE TO ANTICANCER AGENTS (English)

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29 November 2019

author name string

R W BROCKMAN

series ordinal

1

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29 November 2019

publication date

1 January 1963

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Advances in Cancer Research

29 November 2019

published in

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29 November 2019

volume

7

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29 November 2019

page(s)

129-234

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Biosynthesis of nucleic acid purines. III. Guanosine 5′-phosphate formation from xanthosine 5′-phosphate and l-glutamine

29 November 2019

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Further studies on deoxyribonucleic acid-dependent enzymatic synthesis of ribonucleic acid

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Chemical Effects of Ionizing Radiation on Deoxyribonucleic Acid in Dilute Aqueous Solution

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Some properties of Yoshida sarcoma cells resistant of methyl-bis-(beta-chlorethyl)-amine N-oxide

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A Comparative Study of the Mode of Action of X-Rays and Alkylating Agents

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Non-Protein Sulphydryl Group in the Original Strain and Sub-line of the Ascites Tumour resistant to Alkylating Reagents

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THE EFFECTS OF PYRIMIDINES ON THE GROWTH OF LACTOBACILLUS CASEI

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Symposium on the experimental pharmacology and clinical use of antimetabolites. VII. Folic acid antagonists

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Massive Incorporation of 5-Fluorouracil into a Bacterial Ribonucleic Acid

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Properties of L cells resistant to 5-bromodeoxyuridine

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Effect of 3-methylcholanthrene on the endocrine system and metabolism of the rat and its influence to retard growth of mammary tumors hitherto refractory

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Studies on the conversion of deoxyuridylic acid to thymidylic acid by a soluble extract from rat thymus

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The Enzymatic Incorporation of Ribonucleotides into RNA and the Role of DNA

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Biological activities of 6-mercaptopurine: effects on Streptococcus faecalis

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Mutagenic Action of Mitomycin C on Escherichia coli

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THE MECHANISM OF CHEMICAL MUTAGENESIS. I. KINETIC STUDIES ON THE ACTION OF TRIETHYLENE MELAMINE (TEM) AND AZASERINE.

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Mutagenic effect of azaserine in relation to azaserine resistance in Escherichia coli

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Genetic regulatory mechanisms in the synthesis of proteins

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Concentrative uptake of 6-diazo-5-oxo-L-norleucine by sarcoma 180, liver and muscle in vivo

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Permeability of Ehrlich Cells to Uracil, Thymine and Fluorouracil

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The chemistry of actinomycin D and related compounds

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Mechanism of resistance to 2,6-diaminopurine in Salmonella typhimurium

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7 January 2021

Alterations in purine nucleotide pyrophosphorylases and resistance to purine analogues

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7 January 2021

Amination of uridine nucleotides to cytidine nucleotides by soluble mammalian enzymes; role of glutamine and guanosine nucleotides

1 reference

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7 January 2021

Effects of 5-fluorodeoxyuridine and related halogenated pyrimidines on the sand-dollar embryo.

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7 January 2021

Biogenesis of the actinomycins

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7 January 2021

The selection and utilization of metabolic analogs for nucleic acid synthesis

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7 January 2021

Action of mitomycin C on nucleic acid metabolism in tumor and bacterial cells

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7 January 2021

Degradation of Deoxyribonucleic Acid in Escherichia coli Cells treated with Mitomycin C

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7 January 2021

Interaction of actinomycin C with constituents of nucleic acids

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7 January 2021

Action of Nucleic Acids on the Inhibition of Growth by Actinomycin of Neurospora crassa

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7 January 2021

Purine Metabolism in Tetrahymena and Its Relation to Malignant Cells in Mice

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7 January 2021

The mode of action of actinomycin D

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7 January 2021

Reduced Folic Acid Analogues as Antimetabolites

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7 January 2021

Relative stability to thermal denaturation of deoxyribonucleic acid (DNA) preparations containing bromodeoxyuridine

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7 January 2021

On the effect of some adenine derivatives on the incorporation in vitro of isotopically labelled compounds into the nucleic acids of Ehrlich ascites tumor cells

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7 January 2021

Biochemistry of viruses

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7 January 2021

Response to cortisone and development of cortisone resistance in a cortisone-sensitive lymphosarcoma of the mouse

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7 January 2021

Development of a leukaemia resistant to cyclophosphamide ('Cytoxan').

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7 January 2021

The effect of some purine deoxyribosides on the incorporation of [14C] formate and [32P] orthophosphate into DNA of ascites tumor cells in vitro

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7 January 2021

Origin of the resistance of leukaemic cells to folic acid antagonists.

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7 January 2021

Resistance in leukemic cells to an adenine antagonist, 6-mercaptopurine

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7 January 2021

Some aspects of drug resistance in neoplasms.

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7 January 2021

Development of resistance to folic acid antagonists in a transplantable lymphoid leukemia

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7 January 2021

Response of acute lymphocytic leukemias to the purine antagonist 6-mercaptopurine

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7 January 2021

The relative reactivities of deoxyribonucleotides and of the bases of DNA towards alkylating agents

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7 January 2021

Synthetic polynucleotides and the amino acid code

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7 January 2021

The effects of deoxycorticosterone and other steroids on Neurospora crassa

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7 January 2021

Enzymic formation of 6-mercaptopurine tibo tide.

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7 January 2021

Relationships in streptococci between growth and metabolism of glutamine

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7 January 2021

Effect of 8-azaguanine on utilization of methionine by B. cereus

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7 January 2021

The effects of 8-azaguanine on the biosynthesis of ribonucleic acid in Bacillus cereus

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7 January 2021

The effect of 4-amino-5-imidazolecarboxamide on the incorporation of purines into liver nucleic acids of the mouse

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7 January 2021

Resistance and cross-resistance of Escherichia coli mutants to anticancer agents. 1-Methyl-3-nitro-1-nitrosoguanidine

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7 January 2021

MULTIPLE FORMS OF ENZYMES: TISSUE, ONTOGENETIC, AND SPECIES SPECIFIC PATTERNS.

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7 January 2021

The metabolism of thymidine by murine leukemic lymphoblasts (L5178Y)

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7 January 2021

Inhibition of the growth of mouse leukemia cells in culture by 5-iododeoxyuridine

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7 January 2021

Characteristics and stabilization of DNAase-sensitive protein synthesis in E. coli extracts

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7 January 2021

Distribution of 8-azaguanine in the nucleic acids of Bacillus cereus.

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7 January 2021

Filament formation in E. coli induced by azaserine and other antineoplastic agents

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7 January 2021

Some effects of 5-bromouracil on a thymine-requiring mutant of escherichia coli

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7 January 2021

The action of polynucleotide phosphorylase on 5-halogenouridine-5′ pyrophosphates

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7 January 2021

Increased dihydrofolate reductase activity as a possible basis of drug resistance in leukaemia.

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7 January 2021

Studies on the metabolism of rat ascites tumor with nitrogen mustard sensitive and resistant strains. VI. Inhibition of the in vitro incorporation of C-14-orotic acid into nucleic acids by nitrogen mustard

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7 January 2021

Studies on the metabolism of ratascites-tumors with nitrogen mustard sensitive and resistant strains. IV. On the distribution of various enzymes in the cells of normal liver, regenerating liver and hepatoma.

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7 January 2021

Studies on the metabolism of rat ascites tumor with nitrogen mustard sensitive and resistant strains. V. P32-incorporation into ribonucleic acid in vitro

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7 January 2021

Studies on the metabolism of rat-ascites-tumor with nitrogen mustard sensitive and resistant strains. III. On the incorporation of labelled amino acids into protein in vitro

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7 January 2021

Studies on the metabolism of rat-ascites-tumor with nitrogen mustard sensitive and resistant strains. II. On the oxygen consumption and oxidative phosphorylation

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7 January 2021

Studies on the metabolism of rat-ascites-tumor with nitrogen mustard sensitive and resistant strains. I. On the aerobic and anaerobic glycolysis

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7 January 2021

Teleonomic mechanisms in cellular metabolism, growth, and differentiation

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7 January 2021

Reduction of 5′-cytidylic acid to deoxycytidylic acid by mammalian enzymes

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7 January 2021

Reduction of cytidine nucleotides to deoxycytidine nucleotides by mammalian enzymes

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7 January 2021

Studies concerning inhibition of the synthesis of deoxycytidine by phosphorylated derivatives of thymidine

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7 January 2021

Enzymic synthesis of coenzyme I in relation to chemical control of cell growth

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7 January 2021

Formation in vitro of deoxyadenosine triphosphate from deoxyadenosine in Ehrlich ascites cells

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7 January 2021

On the action mechanism of mitomycin C

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7 January 2021

On the mechanism of action of aminopterin

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7 January 2021

The dependence of cell-free protein synthesis in E. coli upon naturally occurring or synthetic polyribonucleotides

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7 January 2021

Deoxyribonucleic acid-dependent incorporation of nucleotides from nucleoside triphosphates into ribonucleic acid

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7 January 2021

Genetic transformation studies. II. Radiation sensitivity of halogen labeled DNA

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7 January 2021

Inhibition of dihydrofolic reductase by aminopterin and amethopterin

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7 January 2021

Effect of 8-azaguanine on ribonucleic acid and protein synthesis in Bacillus cereus, NCTC 569

1 reference

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7 January 2021

The effect of 8-azaguanine on the ribonucleic acid of the ribosomes in Bacillus cereus.

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7 January 2021

Induction of Phage Formation in the Lysogenic Escherichia coli K-12 by Mitomycin C

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7 January 2021

Bacterial uracil riboside phosphorylase

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7 January 2021

Folic acid antagonists

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Dihydrofolic Acid Reductase

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Studies on folic acid reduction

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Uridine and deoxyuridine phosphorylases from Ehrlich ascites tumor

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Variation in resistance patterns in different neoplasms.

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Sequential blocking of metabolic pathways in vivo

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7 January 2021

Fundamental mechanisms of alkylation

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7 January 2021

Synthesis and biological activities of iododeoxyuridine, an analog of thymidine

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7 January 2021

Incorporation of iododeoxyuridine into the deoxyribonucleic acid of mouse Ehrlich-ascites-tumor cells in vivo

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7 January 2021

Studies in the mouse of the pharmacology of 5-iododeoxyuridine, an analogue of thymidine

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7 January 2021

Limited thymidine uptake in Escherichia coli due to an inducible thymidine phosphorylase

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7 January 2021

[On the mode of action of actinomycins]

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7 January 2021

Purification and properties of a pyrimidine deoxyriboside phosphorylase from Escherichia coli

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7 January 2021

Effect of mitomycin C on the growth of some animal viruses

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7 January 2021

Bacteriocidal action of mitomycin C

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7 January 2021

Effect of actinomycin D on cellular nucleic acid synthesis and virus production

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7 January 2021

Bacteriocidal action of mitomycin C

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7 January 2021

Formation of deoxyguanosine 5′-phosphate from guanosine 5′-phosphate with enzymes from chick embryos

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7 January 2021

Formation of deoxycytidine 5′-phosphate from cytidine 5′-phosphate with enzymes from Escherichia coli

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7 January 2021

Possible Enzymic Mechanism for the Development of Resistance against Fluorouracil in Ascites Tumours

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7 January 2021

3-Enolpyruvylshikimate 5-phosphate, an intermediate in the biosynthesis of anthranillate

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7 January 2021

5-Fluorouracil and mucopeptide biosynthesis by Staphylococcus aureus

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7 January 2021

Characterization of resistance to amethopterin, 8-azaguanine and several fluorinated pyrimidines in the murine lymphocytic neoplasm, P388.

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7 January 2021

In vitro reactions of biological alkylating agents

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7 January 2021

6-Methylmercaptopurine: Identification as Metabolite of 6-Mercaptopurine in vivo and Its Activity in vitro

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7 January 2021

Utilization of preformed purines by sarcoma 180 or hepatoma 134 cells treated with 6-chloropurine or a combination of 6-chloropurine and azaserine

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7 January 2021

Observations on the site of 6-chloropurine-induced inhibition of purine biosynthesis

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7 January 2021

Inhibition of the biosynthesis of purines de novo by 6-chloropurine and azaserine in sensitive and naturally resistant ascites cells

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7 January 2021

Patterns of cellular controls operating in bacteriophage reproduction. II. Effect of 5-fluorouracil on metabolic events in bacteria infected with coliphage T2r

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

The production of actinomycins by controlled biosyntheses: the F actinomycins

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7 January 2021

[Effect of carcinostatic ethyleneimine compounds on the DPN content of therapy-resistant tumors].

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7 January 2021

Synthesis of Deoxyribonucleic Acid by Phage-infected Escherichia coli in the Presence of Mitomycin C

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Effect of mitomycin C on the synthesis of bacterial and viral deoxyribonucleic acid

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Severe Distortion by 5-Bromouracil of the Sequence Characteristics of a Bacterial Deoxyribonucleic Acid

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7 January 2021

Selective Inhibition of Formation of Deoxyribonucleic Acid in Escherichia coli by Mitomycin C

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7 January 2021

The utilization of antimetabolites in the study of biochemical processes in living organisms

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7 January 2021

The biochemistry of genetic factors

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7 January 2021

Transformation of Resistance to 8-Azaguanine in Diplococcus pneumoniae

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7 January 2021

Effects of 6-mercaptopurine on experimental tumors.

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7 January 2021

Biochemistry of cancer

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7 January 2021

Preferential incorporation of formate carbon into leukemic blood cells as indicated by autoradiography

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Further studies on formate incorporation by leukemic blood cells

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Accumulation of nucleic acid metabolites in Escherichia coli exposed to the action of 6-azauracil

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Inhibition of Escherichia coli polynucleotide phosphorylase by 6-azauridine diphosphate

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Studies on the mode of action of psicofuranine

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

The metabolism of 8-azapurines

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

The anti-tumour activity of 6-azauracil riboside

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

The biosynthesis of p-aminobenzoic acid: studies on the origin of the amino group

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Effects of halogenated pyrimidines on the growth of tobacco mosaic virus

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7 January 2021

Azaserine, A New Tumour-Inhibitory Substance: Studies with Crocker Mouse Sarcoma 180

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7 January 2021

A biochemical basis for resistance of L1210 mouse leukemia to 6-thioguanine.

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7 January 2021

Genetics of human cell lines. II. Method for determination of mutation rates to drug resistance.

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7 January 2021

Genetics of human cell lines. I. 8-Azaguanine resistance, a selective "single-step" marker

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

The reversible release of protein, ribonucleic acid and deoxyribonuclease from ribosomes

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7 January 2021

Formation of 2-azaadenine and 2, 6-diaminopurine analogues of adenosine triphosphate in human erythrocytes

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

The effect of 5-fluorodeoxyuridine on amphibian embryos

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Antagonists of purine and pyrimidine metabolites and of folic acid

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

THE MECHANISM OF BACTERIAL FRAGILITY PRODUCED BY 5-FLUOROURACIL: THE ACCUMULATION OF CELL WALL PRECURSORS.

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7 January 2021

Chromatographic studies of purine metabolism. I. The effect of azaserine on purine biosynthesis in E. coli using various C14-labeled precursors

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7 January 2021

Chromatographic studies of purine metabolism. III. Effects of A-methopterin on formate-C14 utilization in mice bearing susceptible and dependent L1210 leukemia

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7 January 2021

Enzymatic synthesis of deoxyribonucleic acid. X. Influence of bromouracil substitutions on replication

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7 January 2021

Synthesis of 5-chlorodeoxyuridine and a comparative study of 5-halodeoxyuridines in E. coli

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7 January 2021

The actinomycins and their importance in the treatment of tumors in animals and man. Introduction

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

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7 January 2021

The Structures of Mitomycins A, B and C and Porfiromycin--Part I

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7 January 2021

ENZYMATIC INCORPORATION OF RIBONUCLEOSIDE TRIPHOSPHATES INTO THE INTERPOLYNUCLEOTIDE LINKAGES OF RIBONUCLEIC ACID.

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

On the participation of DNA in RNA biosynthesis

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7 January 2021

Studies on the biosynthesis of deoxyribonucleic acid by extracts of mammalian cells. IV. The phosphorylation of thymidine

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Prevention of the inhibitory effects of urethan, formamide, and N-methylformamide on the growth of Escherichia coli.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Studies with mustards. III. In vivo fixation of C14 from nitrogen mustard-C14H3 in nucleic acid fractions of animal tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Studies with mustards. I. Ion-exchange chromatography of reaction mixtures of purines and pyrimidines with nitrogen mustard

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Studies with mustards. II. Paper chromatography and radioautography of reaction mixtures of various compounds with S35-sulfur mustard

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Potentiated inhibition of Escherichia coli by certain combinations of agents

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Development of mouse ascites tumor sublines resistant to triethylene melamine

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

The actinomycins and their importance in the treatment of tumors in animals and man. Historical background

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

A RIBONUCLEIC ACID FRACTION FROM YEAST RELATED IN COMPOSITION TO DESOXYRIBONUCLEIC ACID.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Effect of Aminopterin and Certain Purine Antagonists on Adenine Nucleotide Levels in Tissues of Tumor-Bearing Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

On the enzymic reduction of folic acid by a purified hydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Incorporation of Halogenated Pyrimidines into the Deoxyribonucleic Acids of Bacterium Coli and its Bacteriophages

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

REVERSAL OF AZASERINE BY PHENYLALANINE.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

The Effects of Nitrogen Mustard on Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Studies on the induction of thymine deficiency and on the effects of thymine and thymidine analogues in Escherichia coli.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Purine metabolism in bacteria. IV. L-azaserine as an inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Effect of deoxycorticosterone on the growth of microorganisms.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

Experimental cancer chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960983-5

7 January 2021

10.1016/S0065-230X(08)60983-5

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14153765%20AND%20SRC:MED&resulttype=core&format=json

29 November 2019

1 reference