Biological function of PDGF-induced PI-3 kinase activity: its role in alpha PDGF receptor-mediated mitogenic signaling. (Q36234748)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7929590%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

title

Biological function of PDGF-induced PI-3 kinase activity: its role in alpha PDGF receptor-mediated mitogenic signaling (English)

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28 October 2019

2

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28 October 2019

author name string

J C Yu

1

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28 October 2019

D Mahadevan

3

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28 October 2019

W Li

4

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28 October 2019

K A Meyers

5

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28 October 2019

J H Pierce

6

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28 October 2019

M A Heidaran

7

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28 October 2019

language of work or name

English

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publication date

1 October 1994

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28 October 2019

published in

Journal of Cell Biology

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28 October 2019

volume

127

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28 October 2019

issue

2

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28 October 2019

page(s)

479-487

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The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

28 October 2019

cites work

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Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

1 October 2017

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Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

1 October 2017

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Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively

1 October 2017

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Structural coincidence of alpha PDGFR epitopes binding to platelet-derived growth factor-AA and a potent neutralizing monoclonal antibody.

1 October 2017

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Comparison of biological properties and transforming potential of human PDGF-A and PDGF-B chains

1 October 2017

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Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

1 October 2017

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Independent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathways

1 October 2017

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Platelet-derived growth factor (PDGF) binding promotes physical association of PDGF receptor with phospholipase C

1 October 2017

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Phosphatidylinositol kinase activity associates with viral p60src protein

1 October 2017

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Signal transduction by the platelet-derived growth factor receptor

1 October 2017

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Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro

1 October 2017

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PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

1 October 2017

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Role of phosphatidylinositol kinase in PDGF receptor signal transduction

1 October 2017

1 reference

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Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae

1 October 2017

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Macrophage-colony-stimulating factor (CSF-1) induces proliferation, chemotaxis, and reversible monocytic differentiation in myeloid progenitor cells transfected with the human c-fms/CSF-1 receptor cDNA

1 October 2017

1 reference

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Thrombin-dependent association of phosphatidylinositol-3 kinase with p60c-src and p59fyn in human platelets

1 October 2017

1 reference

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Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase

1 October 2017

1 reference

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Raf-1 protein kinase is required for growth of induced NIH/3T3 cells

1 October 2017

1 reference

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Defective regulation of mitogen-activated protein kinase activity in a 3T3 cell variant mitogenically nonresponsive to tetradecanoyl phorbol acetate

1 October 2017

1 reference

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Phosphorylation of c-jun mediated by MAP kinases.

1 October 2017

1 reference

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Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases

1 October 2017

1 reference

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cDNA cloning of a Novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor

1 October 2017

1 reference

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Oncogenes and signal transduction

1 October 2017

1 reference

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Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

1 October 2017

1 reference

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Deletion or substitution within the alpha platelet-derived growth factor receptor kinase insert domain: effects on functional coupling with intracellular signaling pathways

1 October 2017

1 reference

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Platelet-derived growth factor (PDGF)-dependent association of phospholipase C-gamma with the PDGF receptor signaling complex

1 October 2017

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Tyrosine mutations within the alpha platelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transduction

1 October 2017

1 reference

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GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit

1 October 2017

1 reference

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Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

1 October 2017

1 reference

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SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors

1 October 2017

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Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors

1 October 2017

1 reference

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Activation of the MAP kinase pathway by the protein kinase raf

1 October 2017

1 reference

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Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit

1 October 2017

1 reference

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Raf-1 activates MAP kinase-kinase

1 October 2017

1 reference

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Modification of the 85-kilodalton subunit of phosphatidylinositol-3 kinase in platelet-derived growth factor-stimulated cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2120211

Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2120211

Differences in substrate specificities of alpha and beta platelet-derived growth factor (PDGF) receptors. Correlation with their ability to mediate PDGF transforming functions

1 October 2017

1 reference

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Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells

29 June 2018

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erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells

29 June 2018

1 reference

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PDGF induction of tyrosine phosphorylation of GTPase activating protein

29 June 2018

1 reference

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Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor

29 June 2018

1 reference

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Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

29 June 2018

1 reference

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PDGF beta-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex

29 June 2018

1 reference

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MAP kinases: charting the regulatory pathways

29 June 2018

1 reference

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Transformation of NIH3T3 fibroblasts by an expression vector for the human epidermal growth factor precursor.

29 June 2018

1 reference

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Signal transduction through the EGF receptor transfected in IL-3-dependent hematopoietic cells

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7929590

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.127.2.479

1 reference

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28 October 2019

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28 October 2019

PubMed publication ID

7929590

1 reference

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