DISC1-ATF4 transcriptional repression complex: dual regulation of the cAMP-PDE4 cascade by DISC1. (Q37061724)

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28 February 2020

title

DISC1-ATF4 transcriptional repression complex: dual regulation of the cAMP-PDE4 cascade by DISC1 (English)

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1

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author name string

C Frank

2

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K Ishizuka

3

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A Baccarella

4

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Y-U Park

5

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28 February 2020

Z Flood

6

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S K Park

7

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A Sawa

8

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L-H Tsai

9

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language of work or name

English

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publication date

16 April 2013

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28 February 2020

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volume

18

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issue

8

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page(s)

898-908

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Dopamine supports coupling of attention-related networks

28 February 2020

cites work

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A new model of Pde4d deficiency: genetic knock-down of PDE4D enzyme in rats produces an antidepressant phenotype without spatial cognitive effects.

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DISC1 variants 37W and 607F disrupt its nuclear targeting and regulatory role in ATF4-mediated transcription

29 September 2017

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29 September 2017

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PKA phosphorylation of NDE1 is DISC1/PDE4 dependent and modulates its interaction with LIS1 and NDEL1

29 September 2017

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NMDA receptor regulates migration of newly generated neurons in the adult hippocampus via Disrupted-In-Schizophrenia 1 (DISC1)

29 September 2017

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29 September 2017

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Catecholamine influences on dorsolateral prefrontal cortical networks

29 September 2017

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DISC1-dependent switch from progenitor proliferation to migration in the developing cortex

29 September 2017

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Mutant DISC1 affects methamphetamine-induced sensitization and conditioned place preference: a comorbidity model.

29 September 2017

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Control of activating transcription factor 4 (ATF4) persistence by multisite phosphorylation impacts cell cycle progression and neurogenesis.

29 September 2017

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Dixdc1 is a critical regulator of DISC1 and embryonic cortical development

29 September 2017

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Gene models of schizophrenia: DISC1 mouse models

29 September 2017

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Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits

29 September 2017

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Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

29 September 2017

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Underpinning compartmentalised cAMP signalling through targeted cAMP breakdown

29 September 2017

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Differential association of phosphodiesterase 4D isoforms with beta2-adrenoceptor in cardiac myocytes

29 September 2017

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ATF4-dependent transcription mediates signaling of amino acid limitation

29 September 2017

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DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212

29 September 2017

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Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling

29 September 2017

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Development of hippocampal mossy fiber synaptic outputs by new neurons in the adult brain

29 September 2017

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Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly.

29 September 2017

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Recruitment of PCM1 to the centrosome by the cooperative action of DISC1 and BBS4: a candidate for psychiatric illnesses

29 September 2017

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Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain

29 September 2017

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29 September 2017

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Isoform-selective susceptibility of DISC1/phosphodiesterase-4 complexes to dissociation by elevated intracellular cAMP levels.

29 September 2017

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Activating transcription factor 4.

29 September 2017

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29 September 2017

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ATF4 differentially regulates transcriptional activation of myeloid-specific genes by C/EBPepsilon and C/EBPalpha

29 September 2017

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DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1

29 September 2017

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DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1

29 September 2017

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Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice

29 September 2017

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A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development

29 September 2017

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DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling

29 September 2017

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Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia

29 September 2017

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Identification and characterization of PDE4A11, a novel, widely expressed long isoform encoded by the human PDE4A cAMP phosphodiesterase gene

29 September 2017

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Leptin regulation of bone resorption by the sympathetic nervous system and CART

29 September 2017

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Splice variants of the cyclic nucleotide phosphodiesterase PDE4D are differentially expressed and regulated in rat tissue.

29 September 2017

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DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation

29 September 2017

1 reference

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Cyclic AMP-dependent transcriptional up-regulation of phosphodiesterase 4D5 in human airway smooth muscle cells. Identification and characterization of a novel PDE4D5 promoter

29 September 2017

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ATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene

29 September 2017

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Disruption of two novel genes by a translocation co-segregating with schizophrenia

29 September 2017

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Subcellular localization of rolipram-sensitive, cAMP-specific phosphodiesterases. Differential targeting and activation of the splicing variants derived from the PDE4D gene

29 September 2017

1 reference

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Identification of cyclic AMP-phosphodiesterase variants from the PDE4D gene expressed in human peripheral mononuclear cells

29 September 2017

1 reference

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Site-directed mutagenesis by overlap extension using the polymerase chain reaction

29 September 2017

1 reference

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Phosphodiesterase-4D knock-out and RNA interference-mediated knock-down enhance memory and increase hippocampal neurogenesis via increased cAMP signaling

29 September 2017

1 reference

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Characterization of an intronic promoter of a cyclic adenosine 3',5'-monophosphate (cAMP)-specific phosphodiesterase gene that confers hormone and cAMP inducibility.

27 June 2018

1 reference

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Synergistic interactions between PDE4B and GSK-3: DISC1 mutant mice

27 June 2018

1 reference

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Phosphorylation of cAMP-specific PDE4A5 (phosphodiesterase-4A5) by MK2 (MAPKAPK2) attenuates its activation through protein kinase A phosphorylation.

4 September 2018

1 reference

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Enhanced dopamine function in DISC1-L100P mutant mice: implications for schizophrenia

4 September 2018

1 reference

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Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus.

4 September 2018

1 reference

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Identification and molecular characterization of a novel PDE4D11 cAMP-specific phosphodiesterase isoform.

4 September 2018

1 reference

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Induction of activating transcription factors (ATFs) ATF2, ATF3, and ATF4 in the nucleus accumbens and their regulation of emotional behavior.

4 September 2018

1 reference

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Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia.

4 September 2018

1 reference

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Differential expression of PDE4 cAMP phosphodiesterase isoforms in inflammatory cells of smokers with COPD, smokers without COPD, and nonsmokers

4 September 2018

1 reference

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The gene encoding phosphodiesterase 4D confers risk of ischemic stroke

4 September 2018

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Antidepressant-like profile and reduced sensitivity to rolipram in mice deficient in the PDE4D phosphodiesterase enzyme

4 September 2018

1 reference

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Regulation of cAMP-specific phosphodiesterases type 4B and 4D (PDE4) splice variants by cAMP signaling in primary cortical neurons

4 September 2018

1 reference

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Is up-regulation of phosphodiesterase 4 activity by PGE2 involved in the desensitization of beta-mimetics in late pregnancy human myometrium?

4 September 2018

1 reference

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Co-ordinated action of DISC1, PDE4B and GSK3β in modulation of cAMP signalling

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23587879

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/MP.2013.38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23587879%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23587879%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

PubMed publication ID

23587879

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23587879%20AND%20SRC:MED&resulttype=core&format=json