Developmental drift as a mechanism for aging: lessons from nematodes (Q38152283)

29 August 2017

title

Developmental drift as a mechanism for aging: lessons from nematodes (English)

1 reference

29 August 2017

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24122213%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Marco Lezzerini

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24122213%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Reuben L Smith

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24122213%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

publication date

1 December 2013

1 reference

29 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24122213%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24122213%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24122213%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

693-701

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24122213%20AND%20SRC:MED&resulttype=core&format=json

Motif module map reveals enforcement of aging by continual NF-kappaB activity

1 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Reversal of aging by NFkappaB blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Answering the ultimate question "what is the proximal cause of aging?"

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Quantitative measures of aging in the nematode Caenorhabditis elegans. I. Population and longitudinal studies of two behavioral parameters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

An elt-3/elt-5/elt-6 GATA transcription circuit guides aging in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

ceh-16/engrailed patterns the embryonic epidermis of Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Wnt/β-catenin signaling and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Lifespan regulation by evolutionarily conserved genes essential for viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Timing requirements for insulin/IGF-1 signaling in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Age-associated elevation of hypothalamic, threshold to feedback control, and its role in development, ageine, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Against the oxidative damage theory of aging: superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

In vivo spectrofluorimetry reveals endogenous biomarkers that report healthspan and dietary restriction in Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Multiple redundant Wnt signaling components function in two processes during C. elegans vulval development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

C. elegans GATA factors EGL-18 and ELT-6 function downstream of Wnt signaling to maintain the progenitor fate during larval asymmetric divisions of the seam cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Opposing Wnt pathways orient cell polarity during organogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Viewing molecular mechanisms of ageing through a lens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Aging: a theory based on free radical and radiation chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Shared principles in NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Caenorhabditis elegans lifespan extension caused by treatment with an orally active ROS-generator is dependent on DAF-16 and SIR-2.1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Genomic analysis of gene expression in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Asymmetric localization of numb in the chick somite and the influence of myogenic signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Metabolic networks of longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

The many faces of insulin-like peptide signalling in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Protein oxidation during aging of the nematode Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Aging can be genetically dissected into component processes using long-lived lines of Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Changes in gene expression associated with developmental arrest and longevity in Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

A C. elegans mutant that lives twice as long as wild type

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

GATA6 haploinsufficiency causes pancreatic agenesis in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

A small-molecule agonist of the Wnt signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Augmented Wnt signaling in a mammalian model of accelerated aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Transcriptional profile of aging in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Wnt/beta-catenin signaling: components, mechanisms, and diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Loss of intestinal nuclei and intestinal integrity in aging C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Reproduction and longevity: secrets revealed by C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Genetic analysis of age-dependent defects of the Caenorhabditis elegans touch receptor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Integration of β-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

The overexpression of major antioxidant enzymes does not extend the lifespan of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

A new look at TCF and beta-catenin through the lens of a divergent C. elegans Wnt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

OrthoList: a compendium of C. elegans genes with human orthologs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Quantitative evidence for conserved longevity pathways between divergent eukaryotic species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Regulation and cell autonomy during postembryonic development of Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Prediction of C. elegans longevity genes by human and worm longevity networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Spontaneous age-related neurite branching in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

The endocrine regulation of aging by insulin-like signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Model organisms as a guide to mammalian aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Superoxide dismutase is dispensable for normal animal lifespan

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

The longevity of Caenorhabditis elegans in soil

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Pleiotropy, Natural Selection, and the Evolution of Senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

The trifecta of aging in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

The signaling hubs at the crossroad of longevity and age-related disease networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

The GATA transcription factor egl-27 delays aging by promoting stress resistance in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

A Measurable increase in oxidative damage due to reduction in superoxide detoxification fails to shorten the life span of long-lived mitochondrial mutants of Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Direct and indirect gene regulation by a life-extending FOXO protein in C. elegans: roles for GATA factors and lipid gene regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

GATA Transcription Factors and Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3

Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9462-3