Recombinant vaccines against leptospirosis. (Q40005348)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22048111%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Recombinant vaccines against leptospirosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22048111%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22048111%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Alan J.A. McBride

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22048111%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

author name string

André A Grassmann

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22048111%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Daiane D Hartwig

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22048111%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Samuel R Félix

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22048111%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Éverton F da Silva

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22048111%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

publication date

1 November 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22048111%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22048111%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22048111%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22048111%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

page(s)

1215-1224

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22048111%20AND%20SRC:MED&resulttype=core&format=json

Leptospirosis: a zoonotic disease of global importance

15 January 2020

cites work

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Leptospirosis: skin wounds and control strategies, Thailand, 1999.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Leptospira: the dawn of the molecular genetics era for an emerging zoonotic pathogen

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Epidemic leptospirosis associated with pulmonary hemorrhage-Nicaragua, 1995.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Leptospirosis in "Eco-Challenge" athletes, Malaysian Borneo, 2000.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Sporadic urban leptospirosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Impact of environment and social gradient on Leptospira infection in urban slums

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

21 January 2018

The antipoverty vaccines

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Further determination of DNA relatedness between serogroups and serovars in the family Leptospiraceae with a proposal for Leptospira alexanderi sp. nov. and four new Leptospira genomospecies

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Leptospira and leptospirosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

An imprint method for detecting leptospires in the hamster model of vaccine-mediated immunity for leptospirosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Comparative genomics of two Leptospira interrogans serovars reveals novel insights into physiology and pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Genome reduction in Leptospira borgpetersenii reflects limited transmission potential

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Leptospirosis-associated severe pulmonary hemorrhagic syndrome, Salvador, Brazil

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Clinical spectrum of pulmonary involvement in leptospirosis in a region of endemicity, with quantification of leptospiral burden

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

High serum nitric oxide levels in patients with severe leptospirosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

HLA-DQ6 and ingestion of contaminated water: possible gene-environment interaction in an outbreak of Leptospirosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Determining risk for severe leptospirosis by molecular analysis of environmental surface waters for pathogenic Leptospira

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Evaluation of four whole-cell Leptospira-based serological tests for diagnosis of urban leptospirosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

A mountain out of a molehill: do we treat acute leptospirosis, and if so, with what?

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Strategies for diagnosis and treatment of suspected leptospirosis: a cost-benefit analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

A monoclonal antibody reacting with a determinant on leptospiral lipopolysaccharide protects guinea pigs against leptospirosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Persistence of anti-leptospiral IgM, IgG and agglutinating antibodies in patients presenting with acute febrile illness in Barbados 1979-1989.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Protective killed Leptospira borgpetersenii vaccine induces potent Th1 immunity comprising responses by CD4 and gammadelta T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Comparison of three different leptospiral vaccines for induction of a type 1 immune response to Leptospira borgpetersenii serovar Hardjo.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

A Leptospira borgpetersenii Serovar Hardjo Vaccine Induces a Th1 Response, Activates NK Cells, and Reduces Renal Colonization

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

A methylated phosphate group and four amide-linked acyl chains in leptospira interrogans lipid A. The membrane anchor of an unusual lipopolysaccharide that activates TLR2

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Differential TLR recognition of leptospiral lipid A and lipopolysaccharide in murine and human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Toll-like receptor 4 protects against lethal Leptospira interrogans serovar icterohaemorrhagiae infection and contributes to in vivo control of leptospiral burden

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Potent innate immune response to pathogenic leptospira in human whole blood

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Current status of leptospirosis in Japan and Philippines

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Leptospirosis in the Asia Pacific region

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Pathogenic Leptospira species express surface-exposed proteins belonging to the bacterial immunoglobulin superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Expression and immunologic characterization of recombinant heat shock protein 58 of Leptospira species: a major target antigen of the humoral immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

LipL21 Is a Novel Surface-Exposed Lipoprotein of Pathogenic Leptospira Species

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Characterization of the immunogenic and antigenic potential of putative lipoproteins from Leptospira interrogans.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

In silico and microarray-based genomic approaches to identifying potential vaccine candidates against Leptospira interrogans

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

The leptospiral major outer membrane protein LipL32 is a lipoprotein expressed during mammalian infection

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Global analysis of outer membrane proteins from Leptospira interrogans serovar Lai.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Molecular evolution and mosaicism of leptospiral outer membrane proteins involves horizontal DNA transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Identification of the hemolysis-associated protein 1 as a cross-protective immunogen of Leptospira interrogans by adenovirus-mediated vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Protection against Leptospira interrogans sensu lato challenge by DNA immunization with the gene encoding hemolysin-associated protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Recombinant Mycobacterium bovis BCG expressing the LipL32 antigen of Leptospira interrogans protects hamsters from challenge.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Genetic diversity of the Leptospiral immunoglobulin-like (Lig) genes in pathogenic Leptospira spp.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Distribution of the leptospiral immunoglobulin-like (lig) genes in pathogenic Leptospira species and application of ligB to typing leptospiral isolates

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Physiological osmotic induction of Leptospira interrogans adhesion: LigA and LigB bind extracellular matrix proteins and fibrinogen

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Heterologous expression of pathogen-specific genes ligA and ligB in the saprophyte Leptospira biflexa confers enhanced adhesion to cultured cells and fibronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

The multifunctional LigB adhesin binds homeostatic proteins with potential roles in cutaneous infection by pathogenic Leptospira interrogans

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Leptospira immunoglobulin‐like protein B (LigB) binding to the C‐terminal fibrinogen αC domain inhibits fibrin clot formation, platelet adhesion and aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

A domain of the Leptospira LigB contributes to high affinity binding of fibronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Leptospiral immunoglobulin-like proteins elicit protective immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

High yield expression of leptospirosis vaccine candidates LigA and LipL32 in the methylotrophic yeast Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Immunoprotection of recombinant leptospiral immunoglobulin-like protein A against Leptospira interrogans serovar Pomona infection

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Evaluation of protective immunity of Leptospira immunoglobulin like protein A (LigA) DNA vaccine against challenge in hamsters.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Immunogenicity and protective efficacy of recombinant Leptospira immunoglobulin-like protein B (rLigB) in a hamster challenge model

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Evaluation of novel fusion proteins derived from extracellular matrix binding domains of LigB as vaccine candidates against leptospirosis in a hamster model

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Advances in saponin-based adjuvants

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Immune mechanisms of protection: can adjuvants rise to the challenge?

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Leptospira immunoglobulin-like protein A variable region (LigAvar) incorporated in liposomes and PLGA microspheres produces a robust immune response correlating to protective immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Immunogenicity of the recombinant leptospiral putative outer membrane proteins as vaccine candidates.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Leptosome-entrapped leptospiral antigens conferred significant higher levels of protection than those entrapped with PC-liposomes in a hamster model

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Immune response and prophylactic efficacy of smegmosomes in a hamster model of leptospirosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

The OmpA-like protein Loa22 is essential for leptospiral virulence

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Molecular cloning and characterization of a novel leptospiral lipoprotein with OmpA domain

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Identification and characterization of OmpA-like proteins as novel vaccine candidates for Leptospirosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Characterization of leptospiral proteins that afford partial protection in hamsters against lethal challenge with Leptospira interrogans

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Canine leptospirosis--do we have a problem?

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Diagnosis of leptospirosis: a reemerging disease of companion animals

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

THE ETIOLOGY, MODE OF INFECTION, AND SPECIFIC THERAPY OF WEIL'S DISEASE (SPIROCHAETOSIS ICTEROHAEMORRHAGICA).

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Preliminary characterization of Mus musculus-derived pathogenic strains of Leptospira borgpetersenii serogroup Ballum in a hamster model

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

The terminal portion of leptospiral immunoglobulin-like protein LigA confers protective immunity against lethal infection in the hamster model of leptospirosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Characterization of virulence of Leptospira isolates in a hamster model

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Highly virulent Leptospira borgpetersenii strain characterized in the hamster model

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

THE RAT AS A CARRIER OF SPIROCHAETA ICTEROHAEMORRHAGIAE, THE CAUSATIVE AGENT OF WEIL'S DISEASE (SPIROCHAETOSIS ICTEROHAEMORRHAGICA).

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Rattus norvegicus as a model for persistent renal colonization by pathogenic Leptospira interrogans

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Changes in lipopolysaccharide O antigen distinguish acute versus chronic Leptospira interrogans infections

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Attenuated nephritis in inducible nitric oxide synthase knockout C57BL/6 mice and pulmonary hemorrhage in CB17 SCID and recombination activating gene 1 knockout C57BL/6 mice infected with Leptospira interrogans

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

THE SERUM TREATMENT OF WEIL'S DISEASE (SPIROCHAETOSIS ICTEROHAEMORRHAGICA).

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Pathogenesis of leptospirosis: the influence of genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Clinical diagnosis and geographic distribution of leptospirosis, Thailand

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

TLR4- and TLR2-mediated B cell responses control the clearance of the bacterial pathogen, Leptospira interrogans

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944

Outbreak of Leptospirosis among Triathlon Participants and Community Residents in Springfield, Illinois, 1998

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FHV.7.11.17944