Hypoxia-inducible factor 1alpha (HIF-1alpha)-mediated hypoxia increases BACE1 expression and beta-amyloid generation (Q40170530)

18 September 2017

title

Hypoxia-inducible factor 1alpha (HIF-1alpha)-mediated hypoxia increases BACE1 expression and beta-amyloid generation (English)

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18 September 2017

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Xian Zhang

1

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18 September 2017

Kun Zhou

2

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18 September 2017

Ruishan Wang

3

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18 September 2017

Jiankun Cui

4

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18 September 2017

Stuart A Lipton

5

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18 September 2017

Francesca-Fang Liao

6

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18 September 2017

Huaxi Xu

7

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18 September 2017

Yun-wu Zhang

8

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18 September 2017

language of work or name

English

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publication date

15 February 2007

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Journal of Biological Chemistry

18 September 2017

number of pages

8

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based on heuristic

inferred from page(s)

published in

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18 September 2017

volume

282

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18 September 2017

issue

15

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18 September 2017

page(s)

10873-10880

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Pathological and physiological functions of presenilins

18 September 2017

cites work

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21 January 2018

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21 January 2018

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21 January 2018

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BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein

21 January 2018

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21 January 2018

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21 January 2018

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BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease

21 January 2018

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21 January 2018

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21 January 2018

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The transcription factor Yin Yang 1 is an activator of BACE1 expression

21 January 2018

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Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease

21 January 2018

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21 January 2018

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HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

21 January 2018

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21 January 2018

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21 January 2018

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Accelerated accumulation of N- and C-terminal beta APP fragments and delayed recovery of microtubule-associated protein 1B expression following stroke in aged rats.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Chronic hypoxia in the human neuroblastoma SH-SY5Y causes reduced expression of the putative alpha-secretases, ADAM10 and TACE, without altering their mRNA levels

21 January 2018

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Altered processing of amyloid precursor protein in the human neuroblastoma SH-SY5Y by chronic hypoxia

21 January 2018

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Altered processing of the amyloid precursor protein and decreased expression of ADAM 10 by chronic hypoxia in SH-SY5Y: no role for the stress-activated JNK and p38 signalling pathways

21 January 2018

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21 January 2018

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21 January 2018

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Increased BACE1 maturation contributes to the pathogenesis of Alzheimer's disease in Down syndrome

21 January 2018

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Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M608856200

1 reference

release_ef77lvyyvbfs3g32pn52rgmvwu

18 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ef77lvyyvbfs3g32pn52rgmvwu

mapped directly with Wikidata item

24 November 2022

based on heuristic

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